Open Journal of Medical Sciences <p>Open Journal of Medical Sciences(OJMS) is an international, peer-reviewed, open access, scientific journal, providing a platform for advances in basic, translational and clinical research. The journal aims to publish original research, review articles and short communications about molecular and cellular processes in disease, in order to increase understanding of the fundamental principles and biological questions of medicine. Researchers in academic and clinical settings as well as health professionals are encouraged to publish their theoretical and experimental results in this journal, which aims to integrate expertise from the molecular and translational sciences, therapeutics, and diagnostics in different medical specialties.</p> en-US Open Journal of Medical Sciences 2770-5544 A Case Report of Sagittal Sinus Thrombosis and Pulmonary Embolism in an Asymptomatic SARS-CoV-2 Infection <p><strong>Background: </strong>Vascular thrombotic events such as pulmonary embolisms have been frequently reported in the course of SARS-Cov-2 infection. However, sagittal sinus thrombus is extremely rare, and patients may lack other appealing Covid-19 infection symptoms. <strong>Case report: </strong>46-year-old female with past medical history of Hyperlipidemia, Hypertension presented to Emergency room with headache, chest pain, vomiting. SARS-CoV-2 IgG Antibodies were reactive. Except for elevated PTT-Lupus Anticoagulant at 50 Sec, Hypercoagulable workup was negative. The MRI venogram findings were consistent with the Dural thrombus of superior sagittal sinus. Patient subsequently developed chest pain, and Computed tomography angiography found pulmonary emboli within segmental branches of the right lower lobe pulmonary artery. Patient was managed in the ICU with Heparin and switched to Coumadin for discharged. <strong>Conclusion:</strong> The incidence of Cerebral Venous Sinus thrombus (CVST) among Covid-19 patients is inferior to 0.02%. And most of the patients lack typical Covid-19 presentations such as pneumonia. The lack of symptoms may promote the insidious course of pre-thrombotic events that lead to CVST. However more Retrospective studies are necessary to established consistent odd ratios. Due to the higher mortality associated with CVST and the ongoing of Covid-19 pandemic, we recommend a higher level of clinical suspicion.</p> Alexa Kahn Hafsa Sabzposh Derman Ozdemir Mohammad Zaman Copyright (c) 2021 Open Journal of Medical Sciences 2022-06-28 2022-06-28 5 8 Idiopathic Retroperitoneal Fibrosis: A Case of Women 75-years Old Without Ureteral Involvement <p>A 75-year-old female is referred for evaluation of a progressive leg swelling. Angiological and MRI evaluation show the presence of inflammatory tissue surrounding the aorta and the left iliac vessels, causing significant stenosis. Upon suspicion of retroperitoneal fibrosis, we actively seek for secondary causes such as malignancies, autoimmune diseases and infections, as well as IgG4-related disease. All investigations result negative and we make the diagnosis of idiopathic retroperitoneal fibrosis. Steroid therapy was started and we observed a rapid amelioration of symptoms and radiological disappearance of the inflammatory tissue around the aorta.</p> Fabrizio Foieni Alina Liedke Luca Spinedi Rita Monotti Copyright (c) 2021 Open Journal of Medical Sciences 2021-12-13 2021-12-13 1 4 Measurement of conversion factor into mean glandular dose in mammography using OSL dosimeters <p><strong>Background: </strong>Currently, the DRL quantity in mammography are evaluated in terms of mean glandular dose (MGD). Since the MGD cannot be measured directly, it can be obtained by calculation using the equation (D=K*g*c*s). In previous studies, the conversion factor g was calculated by Monte Carlo simulation and is not reported from actual measurements. In this study, we focused on the g-factor, which is a conversion factor to the MGD at 50% glandularity, and attempted to measure it using a nanoDot dosimeter to see if it can be used in mammography. <strong>Methods: </strong>The nanoDot dosimeters were inserted in a PMMA phantom at depths ranging from 0 cm to 6 cm in 1 cm increments, and measurements were made in three HVLs of 0.3 mmAl, 0.35 mmAl, and 0.4 mmAl HVL. The g-factor was calculated from the nanoDot dosimeter values using a conversion equation. <strong>Results and Discussion:</strong> The measured g-factors for all the HVLs were in close agreement with those of Dance et al. The values of the previous studies did not include the backscatter factor, which may have underestimated the MGD. The difference was smaller for the 0.4 mm Al. Compared to the other HVLs, the 0.4 mm Al was measured without a compression plate, which may have been influenced by the presence or absence of a compression plate. <strong>Conclusion:</strong> The nanoDot dosimeters were used to calculate g-factors. The results agreed with those of previous studies within uncertainty. This indicates that nanoDot dosimeters can be used in the mammography field.</p> Yasuki Asada Honoka Inagaki Kaito Iwase Mio Taniguchi Yuya Nagake Miuna Hayashi Copyright (c) 2021 Open Journal of Medical Sciences 2022-10-29 2022-10-29 9 16