Mashhad is one of the important metropolitans in the northeast of Iran with over 25 million tourists per year. After evaluating the physical space of Mashhad in terms of semantics and identity with the aim of promoting tourism, 127 valuable places with cultural, historical, and religious values were identified, assessed, and analyzed using a Geographic Information Systems (GIS). Therefore, the appropriate distribution of tourist routes for travelers to visit the city of Mashhad was done and 10 corridors and zones were selected. The basis of this choice was the existence of a valuable place at origin and destination of the routes and the existence of appropriate tourism, commercial, welfare and cultural infrastructure and ability to access various uses. Percentage and number of valuable places in each proposed route necessarily meant percentage of the total, excluding repetition in other routes.