|
| Characteristics |
Total (n = 2137) |
Serum Alpha-1-Acid Glycoprotein (g/L) |
p |
|
|
| Q1 (n = 534) |
Q2 (n = 529) |
Q3 (n = 538) |
Q4 (n = 536) |
|
|
| α1-AGP, g/L |
0.82±0.2 |
0.50±0.1 |
0.70±0.0 |
0.80±0.0 |
1.10±0.2 |
<0.001 |
|
| Age, years |
34.6 ± 8.5 |
34.3 ± 8.5 |
34.4 ± 8.8 |
34.8 ± 8.4 |
35.1 ± 8.5 |
0.381 |
|
| Race, n (%) |
|
|
|
|
|
0.219 |
|
| Non-Hispanic White |
686 (32.1) |
156 (29.2) |
166 (31.4) |
172 (32.0) |
192 (35.8) |
|
|
| Non-Hispanic Black |
431 (20.2) |
115 (21.5) |
105 (19.8) |
99 (18.4) |
112 (20.9) |
|
|
| Mexican American |
391 (18.3) |
105 (19.7) |
99 (18.7) |
110 (20.4) |
77 (14.4) |
|
|
| Other Race |
629 (29.4) |
158 (29.6) |
159 (30.1) |
157 (29.2) |
155 (28.9) |
|
|
| Educational level, n (%) |
|
|
|
|
|
0.308 |
|
| High school or less |
151 (7.1) |
37 (6.9) |
46 (8.7) |
37 (6.9) |
31 (5.8) |
|
|
| Some College |
615 (28.8) |
153 (28.7) |
154 (29.1) |
167 (31.0) |
141 (26.4) |
|
|
| College or above |
1370 (64.1) |
344 (64.4) |
329 (62.2) |
334 (62.1) |
363 (67.9) |
|
|
| Marital status, n (%) |
|
|
|
|
|
0.121 |
|
| Married or living with partner |
1271 (59.5) |
322 (60.3) |
298 (56.3) |
340 (63.2) |
311 (58.1) |
|
|
| Living alone |
865 (40.5) |
212 (39.7) |
231 (43.7) |
198 (36.8) |
224 (41.9) |
|
|
| Hypertension, n (%) |
339 (15.9) |
72 (13.5) |
84 (15.9) |
92 (17.1) |
91 (17.0) |
0.333 |
|
| Diabetes, n (%) |
115 (5.4) |
32 (6.0) |
26 (4.9) |
28 (5.2) |
29 (5.4) |
0.887 |
|
| Physical activity, n (%) |
|
|
|
|
|
0.060 |
|
| Sedentary |
1184 (55.5) |
284 (53.2) |
280 (52.9) |
307 (57.1) |
313 (58.6) |
|
|
| Moderate |
551 (25.8) |
137 (25.7) |
158 (29.9) |
139 (25.8) |
117 (21.9) |
|
|
| Vigorous |
400 (18.7) |
113 (21.2) |
91 (17.2) |
92 (17.1) |
104 (19.5) |
|
|
| Smoking status, n (%) |
|
|
|
|
|
0.251 |
|
| Never |
1491 (69.8) |
381 (71.3) |
381 (72.0) |
368 (68.5) |
361 (67.5) |
|
|
| Former |
258 (12.1) |
60 (11.2) |
63 (11.9) |
75 (14.0) |
60 (11.2) |
|
|
| Current |
386 (18.1) |
93 (17.4) |
85 (16.1) |
94 (17.5) |
114 (21.3) |
|
|
| BMI, kg/m2 |
30.0 ± 8.1 |
30.0 ± 7.8 |
30.0 ± 8.1 |
29.9 ± 8.2 |
30.0 ± 8.4 |
0.998 |
|
| SBP, mmHg |
114.7 ± 13.4 |
114.3 ± 12.6 |
115.2 ± 13.1 |
114.8 ± 13.4 |
114.5 ± 14.2 |
0.751 |
|
| DBP, mmHg |
69.9 ± 10.6 |
69.5 ± 10.4 |
69.4 ± 11.1 |
70.2 ± 10.0 |
70.3 ± 10.8 |
0.334 |
|
| WBC, *109/L |
7.7 ± 2.3 |
6.9 ± 2.0 |
7.6 ± 2.1 |
7.6 ± 2.0 |
8.8 ± 2.6 |
<0.001 |
|
| HGB, g/dL |
13.0 ± 1.3 |
12.9 ± 1.2 |
13.0 ± 1.2 |
13.1 ± 1.3 |
13.0 ± 1.5 |
0.289 |
|
| eGFR, mL/min/1.73m2 |
111.7 ± 17.9 |
113.4 ± 18.2 |
112.5 ± 18.2 |
112.0 ± 17.5 |
109.1 ± 17.5 |
<0.001 |
|
| ACR, mg/g |
7.4 (5.1, 12.4) |
7.4 (5.4, 12.6) |
7.8 (5.4, 13.5) |
7.6 (5.1, 12.4) |
7.0 (4.8, 10.9) |
0.005 |
|
| Vitamin D, nmol/L |
56.3 ± 25.5 |
54.6 ± 24.3 |
56.4 ± 23.9 |
55.2 ± 26.7 |
59.1 ± 27.0 |
0.020 |
|
| ALB, g/L |
41.0 ± 3.7 |
41.2 ± 3.9 |
41.0 ± 3.8 |
41.0 ± 3.4 |
40.9 ± 3.9 |
0.711 |
|
| Uric acid, umol/L |
268.9 ± 67.9 |
245.9 ± 58.2 |
260.1 ± 58.0 |
274.2 ± 65.3 |
295.3 ± 78.1 |
<0.001 |
|
| BUN, mmol/L |
4.2 ± 1.4 |
4.2 ± 1.3 |
4.1 ± 1.2 |
4.3 ± 1.7 |
4.2 ± 1.3 |
0.364 |
|
| Bicarbonate, mmol/L |
24.0 ± 2.3 |
24.1 ± 2.3 |
24.0 ± 2.1 |
23.9 ± 2.3 |
24.0 ± 2.2 |
0.448 |
|
| Calcium, mmol/L |
2.3 ± 0.1 |
2.3 ± 0.1 |
2.3 ± 0.1 |
2.3 ± 0.1 |
2.3 ± 0.1 |
0.542 |
|
| Phosphorus, mmol/L |
1.2 ± 0.2 |
1.2 ± 0.2 |
1.2 ± 0.2 |
1.2 ± 0.2 |
1.2 ± 0.2 |
0.006 |
|
| Cholesterol, mmol/L |
4.8 ± 1.0 |
4.8 ± 1.0 |
4.8 ± 1.0 |
4.8 ± 1.0 |
4.7 ± 0.9 |
0.103 |
|
| HDL, mmol/L |
1.5 ± 0.4 |
1.7 ± 0.4 |
1.5 ± 0.4 |
1.4 ± 0.4 |
1.3 ± 0.4 |
<0.001 |
|
| Triglycerides, mmol/L |
1.4 ± 0.9 |
1.1 ± 0.8 |
1.3 ± 0.9 |
1.4 ± 0.9 |
1.6 ± 0.9 |
<0.001 |
|
| HbA1c, % |
5.5 ± 0.9 |
5.3 ± 0.6 |
5.4 ± 0.8 |
5.6 ± 0.9 |
5.7 ± 1.0 |
<0.001 |
|
| Folate, nmol/L |
1114.9 ± 459.1 |
1090.8 ± 417.6 |
1100.4 ± 438.5 |
1089.3 ± 427.2 |
1179.0 ± 537.9 |
0.003 |
|
| hs-CRP, mg/L |
2.4 (0.8, 5.4) |
0.7 (0.4, 2.0) |
1.4 (0.7, 3.4) |
2.8 (1.4, 5.3) |
6.3 (3.3, 11.6) |
<0.001 |
|
| Ferritin, ug/L |
41.0 (20.5, 75.5) |
36.8 (19.4, 69.5) |
39.6 (20.7, 72.7) |
42.5 (21.5, 76.8) |
48.0 (20.9, 83.0) |
0.015 |
|
|
α1-AGP, Serum Alpha-1-Acid Glycoprotein; BMI, Body Mass Index; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure; WBC, White Blood Cell count; HGB, Hemoglobin; eGFR, Estimated Glomerular Filtration Rate; ACR, Albumin-to-Creatinine Ratio; ALB, Albumin; BUN, Blood Urea Nitrogen; HDL, High-Density Lipoprotein; HbA1c, Hemoglobin A1c; hs-CRP, High-Sensitivity C-Reactive Protein.
|
