Article Open Access September 18, 2025

Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?

1
Department of Psychiatry, Charles R Drew University of Medicine and Science, Los Angeles, CA, USA
2
Department of Internal Medicine, Charles R Drew University of Medicine and Science, Los Angeles, CA, USA
3
Department of Public Health, Charles R Drew University of Medicine and Science, Los Angeles, CA, USA
4
Charles R Drew University of Medicine and Science, Los Angeles, CA, USA
5
Mayfair High School, Lakewood, CA, USA
6
Marginalization-related Diminished Returns Center, Los Angeles, CA, USA
7
Department of Health Science, College of Health & Human Services, California State University Long Beach, Long Beach, CA, USA
8
Center for Global Health, College of Health & Human Services, California State University Long Beach, Long Beach, CA, USA
Page(s): 38-51
Received
July 17, 2025
Revised
August 10, 2025
Accepted
September 16, 2025
Published
September 18, 2025
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright: Copyright © The Author(s), 2025. Published by Scientific Publications
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APA Style
Assari, S. , Assari, S. Donovan, A. , Donovan, A. Pallera, J. A. , Pallera, J. A. Assari, G. , Assari, G. Najand, B. , Najand, B. Alaei, K. , & Alaei, K. (2025). Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?. Current Research in Public Health, 5(1), 38-51. https://doi.org/10.31586/ojp.2025.6188
ACS Style
Assari, S. ; Assari, S. Donovan, A. ; Donovan, A. Pallera, J. A. ; Pallera, J. A. Assari, G. ; Assari, G. Najand, B. ; Najand, B. Alaei, K. ; Alaei, K. Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?. Current Research in Public Health 2025 5(1), 38-51. https://doi.org/10.31586/ojp.2025.6188
Chicago/Turabian Style
Assari, Shervin, Shervin Assari. Alexandra Donovan, Alexandra Donovan. John Ashley Pallera, John Ashley Pallera. Gandom Assari, Gandom Assari. Babak Najand, Babak Najand. Kamiar Alaei, and Kamiar Alaei. 2025. "Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?". Current Research in Public Health 5, no. 1: 38-51. https://doi.org/10.31586/ojp.2025.6188
AMA Style
Assari S, Assari SDonovan A, Donovan APallera JA, Pallera JAAssari G, Assari GNajand B, Najand BAlaei K, Alaei K. Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?. Current Research in Public Health. 2025; 5(1):38-51. https://doi.org/10.31586/ojp.2025.6188
@Article{crph6188,
AUTHOR = {Assari, Shervin and Donovan, Alexandra and Pallera, John Ashley and Assari, Gandom and Najand, Babak and Alaei, Kamiar and Alaei, Arash},
TITLE = {Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?},
JOURNAL = {Current Research in Public Health},
VOLUME = {5},
YEAR = {2025},
NUMBER = {1},
PAGES = {38-51},
URL = {https://www.scipublications.com/journal/index.php/OJP/article/view/6188},
ISSN = {2831-5162},
DOI = {10.31586/ojp.2025.6188},
ABSTRACT = {Background: Sexual and gender minority (SGM) youth are at elevated risk for adverse mental health and substance use outcomes. Stressors such as family conflict, discrimination, and trauma have been suggested as possible mediators of these disparities. Aims: This study examined whether family conflict, discrimination, and trauma mediate the associations between SGM identity and adverse outcomes, including suicide attempt, major depressive disorder (MDD), nicotine use, and marijuana use. Methods: Participants were children from the Adolescent Brain Cognitive Development (ABCD) study. SGM identity was reported at baseline, while outcomes included past MDD and suicide attempts as well as future nicotine and marijuana use. Structural equation modeling (SEM) was used to test both direct and indirect pathways linking SGM identity to mental health and behavioral outcomes. Results: No significant mediation was found through family conflict, discrimination, or trauma. Instead, effects of SGM identity were primarily direct: SGM youth had higher odds of past suicide attempts and MDD, as well as future marijuana use, but not future nicotine use. Stressor variables, however, were independently associated with outcomes. Discrimination predicted all outcomes; trauma was positively associated with suicide, nicotine, and marijuana use but not MDD; and family conflict predicted all outcomes except MDD. Conclusion: Family conflict, discrimination, and trauma did not mediate SGM disparities in mental health and substance use, but each emerged as an independent predictor of risk. These findings highlight the complexity of mechanisms underlying SGM-related disparities and suggest the need for future research to explore additional pathways and contextual influences.},
}
%0 Journal Article
%A Assari, Shervin
%A Donovan, Alexandra
%A Pallera, John Ashley
%A Assari, Gandom
%A Najand, Babak
%A Alaei, Kamiar
%A Alaei, Arash
%D 2025
%J Current Research in Public Health

%@ 2831-5162
%V 5
%N 1
%P 38-51

%T Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?
%M doi:10.31586/ojp.2025.6188
%U https://www.scipublications.com/journal/index.php/OJP/article/view/6188
TY  - JOUR
AU  - Assari, Shervin
AU  - Donovan, Alexandra
AU  - Pallera, John Ashley
AU  - Assari, Gandom
AU  - Najand, Babak
AU  - Alaei, Kamiar
AU  - Alaei, Arash
TI  - Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?
T2  - Current Research in Public Health
PY  - 2025
VL  - 5
IS  - 1
SN  - 2831-5162
SP  - 38
EP  - 51
UR  - https://www.scipublications.com/journal/index.php/OJP/article/view/6188
AB  - Background: Sexual and gender minority (SGM) youth are at elevated risk for adverse mental health and substance use outcomes. Stressors such as family conflict, discrimination, and trauma have been suggested as possible mediators of these disparities. Aims: This study examined whether family conflict, discrimination, and trauma mediate the associations between SGM identity and adverse outcomes, including suicide attempt, major depressive disorder (MDD), nicotine use, and marijuana use. Methods: Participants were children from the Adolescent Brain Cognitive Development (ABCD) study. SGM identity was reported at baseline, while outcomes included past MDD and suicide attempts as well as future nicotine and marijuana use. Structural equation modeling (SEM) was used to test both direct and indirect pathways linking SGM identity to mental health and behavioral outcomes. Results: No significant mediation was found through family conflict, discrimination, or trauma. Instead, effects of SGM identity were primarily direct: SGM youth had higher odds of past suicide attempts and MDD, as well as future marijuana use, but not future nicotine use. Stressor variables, however, were independently associated with outcomes. Discrimination predicted all outcomes; trauma was positively associated with suicide, nicotine, and marijuana use but not MDD; and family conflict predicted all outcomes except MDD. Conclusion: Family conflict, discrimination, and trauma did not mediate SGM disparities in mental health and substance use, but each emerged as an independent predictor of risk. These findings highlight the complexity of mechanisms underlying SGM-related disparities and suggest the need for future research to explore additional pathways and contextual influences.
DO  - Does Stress Explain the Effects of Sexual/Gender Minority Status on Children’s Behavioral and Emotional Risk?
TI  - 10.31586/ojp.2025.6188
ER  -