Case Report Open Access December 09, 2025

Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality

1
Specialist, Department of Obstetrics and Gynecology, Maternity and Children Hospital, Al-Kharj, Saudi Arabia
2
Consultant, Department of Obstetrics and Gynecology, Maternity and Children Hospital, Al-Kharj, Saudi Arabia
3
Consultant (Obs./Gyn.), King Saud Medical City, Riyadh, Saudi Arabia
4
MFM Consultant, King Saud Medical City, Riyadh, Saudi Arabia
Page(s): 24-27
Received
October 30, 2025
Revised
December 03, 2025
Accepted
December 08, 2025
Published
December 09, 2025
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright: Copyright © The Author(s), 2025. Published by Scientific Publications
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APA Style
Atif, N. , Atif, N. Bedairy, M. H. H. , Bedairy, M. H. H. Almadani, H. I. , & Almadani, H. I. (2025). Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality. Current Research in Public Health, 4(1), 24-27. https://doi.org/10.31586/ujog.2025.6236
ACS Style
Atif, N. ; Atif, N. Bedairy, M. H. H. ; Bedairy, M. H. H. Almadani, H. I. ; Almadani, H. I. Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality. Current Research in Public Health 2025 4(1), 24-27. https://doi.org/10.31586/ujog.2025.6236
Chicago/Turabian Style
Atif, Noreen, Noreen Atif. Mohamed Hassan Hussein Bedairy, Mohamed Hassan Hussein Bedairy. Hana Ibrahim Almadani, and Hana Ibrahim Almadani. 2025. "Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality". Current Research in Public Health 4, no. 1: 24-27. https://doi.org/10.31586/ujog.2025.6236
AMA Style
Atif N, Atif NBedairy MHH, Bedairy MHHAlmadani HI, Almadani HI. Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality. Current Research in Public Health. 2025; 4(1):24-27. https://doi.org/10.31586/ujog.2025.6236
@Article{crph6236,
AUTHOR = {Atif, Noreen and Bedairy, Mohamed Hassan Hussein and Almadani, Hana Ibrahim and Almajali, Ansam Rateb},
TITLE = {Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality},
JOURNAL = {Current Research in Public Health},
VOLUME = {4},
YEAR = {2025},
NUMBER = {1},
PAGES = {24-27},
URL = {https://www.scipublications.com/journal/index.php/UJOG/article/view/6236},
ISSN = {2831-5162},
DOI = {10.31586/ujog.2025.6236},
ABSTRACT = {Introduction: Colorectal cancer during pregnancy is a complex and rare condition often presenting with benign gastrointestinal symptoms that overlap with normal pregnancy related changes, leading to delayed or misdiagnosis. Further, hepatic metastases may complicate recognition, especially when initially interpreted as benign lesions such as hemangiomas. So, early identification and management are crucial and remain challenging for optimizing maternal and fetal outcomes. Clinical Description: A case of 39-year-old gravida 5 para 4 at 24 weeks+1 day with chronic hypothyroidism, longstanding anemia and a one year history of epigastric + right upper quadrant pain with suspected hemorrhage from a known liver hemangioma. Further imaging suggested a malignant hepatic lesion where colonoscopy and biopsy confirmed stage IV metastatic colon adenocarcinoma with liver and adrenal metastases. Her condition deteriorated and delivered a stillborn infant at 26 weeks of 780 grams following placental abruption. She continued to decline despite supportive care and died. Conclusion: This case illustrates the diagnostic challenges of colorectal cancer in pregnancy where nonspecific symptoms and inaccurate imaging results contributed to delayed diagnosis. The aggressive nature of the disease emphasizes the importance of prompt diagnosis and integrated care approach to improve both maternal and fetal outcome.},
}
%0 Journal Article
%A Atif, Noreen
%A Bedairy, Mohamed Hassan Hussein
%A Almadani, Hana Ibrahim
%A Almajali, Ansam Rateb
%D 2025
%J Current Research in Public Health

%@ 2831-5162
%V 4
%N 1
%P 24-27

%T Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality
%M doi:10.31586/ujog.2025.6236
%U https://www.scipublications.com/journal/index.php/UJOG/article/view/6236
TY  - JOUR
AU  - Atif, Noreen
AU  - Bedairy, Mohamed Hassan Hussein
AU  - Almadani, Hana Ibrahim
AU  - Almajali, Ansam Rateb
TI  - Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality
T2  - Current Research in Public Health
PY  - 2025
VL  - 4
IS  - 1
SN  - 2831-5162
SP  - 24
EP  - 27
UR  - https://www.scipublications.com/journal/index.php/UJOG/article/view/6236
AB  - Introduction: Colorectal cancer during pregnancy is a complex and rare condition often presenting with benign gastrointestinal symptoms that overlap with normal pregnancy related changes, leading to delayed or misdiagnosis. Further, hepatic metastases may complicate recognition, especially when initially interpreted as benign lesions such as hemangiomas. So, early identification and management are crucial and remain challenging for optimizing maternal and fetal outcomes. Clinical Description: A case of 39-year-old gravida 5 para 4 at 24 weeks+1 day with chronic hypothyroidism, longstanding anemia and a one year history of epigastric + right upper quadrant pain with suspected hemorrhage from a known liver hemangioma. Further imaging suggested a malignant hepatic lesion where colonoscopy and biopsy confirmed stage IV metastatic colon adenocarcinoma with liver and adrenal metastases. Her condition deteriorated and delivered a stillborn infant at 26 weeks of 780 grams following placental abruption. She continued to decline despite supportive care and died. Conclusion: This case illustrates the diagnostic challenges of colorectal cancer in pregnancy where nonspecific symptoms and inaccurate imaging results contributed to delayed diagnosis. The aggressive nature of the disease emphasizes the importance of prompt diagnosis and integrated care approach to improve both maternal and fetal outcome.
DO  - Hidden Malignancy in Pregnancy: Metastatic Adenocarcinoma of Colon Disguised as Liver Hemangioma Leading to Maternal Mortality
TI  - 10.31586/ujog.2025.6236
ER  -