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Review Article Open Access August 09, 2023

Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review

Shafqat Rasul 1, Abid Rashid 2, Muhammad Akram 1,*, Umme Laila 1, Rida Zainab 1, Muhammad Talha Khalil 1, Hadji Seydou Mbaye 3, Mourad Ben Said 4, 5, Hanan Sneed Alharbi 6, Hanadi Husni Alabed 7 and Mahmoud Abdel Hameed Shahin 8
1
Department of Eastern Medicine, Government College University Faisalabad, Pakistan
2
Faculty of Medical Sciences, Government College University Faisalabad, Pakistan
3
BCNet International Working Group, IARC/WHO, Dakar, Senegal
4
Service de MicrobiologieetImmunologie, EcoleNationale de MédecineVétérinaire, Univ. Manouba, 2020 SidiThabet, Tunisia
5
Institut Supérieur de Biotechnologie de SidiThabet, Département des Sciences Fondamentales, Univ. Manouba, SidiThabet, Tunisia
6
Nursing department, Ohud hospital, Madinah, KSA
7
Education department, Gama Hospital, Khobar, KSA
8
Associate Professor, Nursing Department, Prince Sultan Military College of Health Sciences, Dhahran, KSA
Publihed in: Current Research in Public Health (Volume 2, Issue 2, 2023)
Page(s): 102-121
DOI: 10.31586/wjcor.2023.727
Received
June 11, 2023
Revised
July 11, 2023
Accepted
August 08, 2023
Published
August 09, 2023
Keywords
Calotropis procera; Medicinal uses; Pharmacological uses; anti-Cancer and anti-fungal activities
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright: Copyright © The Author(s), 2023. Published by Scientific Publications
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Cite This Article

APA Style
Rasul, S. , Rasul, S. Rashid, A. , Rashid, A. Akram, M. , Akram, M. Laila, U. , Laila, U. Zainab, R. , Zainab, R. Khalil, M. T. , Khalil, M. T. Mbaye, H. S. , Mbaye, H. S. Said, M. B. , Said, M. B. Alharbi, H. S. , Alharbi, H. S. Alabed, H. H. , & Alabed, H. H. (2023). Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review. Current Research in Public Health, 2(2), 102-121. https://doi.org/10.31586/wjcor.2023.727
ACS Style
Rasul, S. ; Rasul, S. Rashid, A. ; Rashid, A. Akram, M. ; Akram, M. Laila, U. ; Laila, U. Zainab, R. ; Zainab, R. Khalil, M. T. ; Khalil, M. T. Mbaye, H. S. ; Mbaye, H. S. Said, M. B. ; Said, M. B. Alharbi, H. S. ; Alharbi, H. S. Alabed, H. H. ; Alabed, H. H. Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review. Current Research in Public Health 2023 2(2), 102-121. https://doi.org/10.31586/wjcor.2023.727
Chicago/Turabian Style
Rasul, Shafqat, Shafqat Rasul. Abid Rashid, Abid Rashid. Muhammad Akram, Muhammad Akram. Umme Laila, Umme Laila. Rida Zainab, Rida Zainab. Muhammad Talha Khalil, Muhammad Talha Khalil. Hadji Seydou Mbaye, Hadji Seydou Mbaye. Mourad Ben Said, Mourad Ben Said. Hanan sneed Alharbi, Hanan sneed Alharbi. Hanadi Husni Alabed, and Hanadi Husni Alabed. 2023. "Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review". Current Research in Public Health 2, no. 2: 102-121. https://doi.org/10.31586/wjcor.2023.727
AMA Style
Rasul S, Rasul SRashid A, Rashid AAkram M, Akram MLaila U, Laila UZainab R, Zainab RKhalil MT, Khalil MTMbaye HS, Mbaye HSSaid MB, Said MBAlharbi HS, Alharbi HSAlabed HH, Alabed HH. Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review. Current Research in Public Health. 2023; 2(2):102-121. https://doi.org/10.31586/wjcor.2023.727 
@Article{crph727,
AUTHOR = {Rasul, Shafqat and Rashid, Abid and Akram, Muhammad and Laila, Umme and Zainab, Rida and Khalil, Muhammad Talha and Mbaye, Hadji Seydou and Said, Mourad Ben and Alharbi, Hanan sneed and Alabed, Hanadi Husni and Shahin, Mahmoud Abdel Hameed},
TITLE = {Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review},
JOURNAL = {Current Research in Public Health},
VOLUME = {2},
YEAR = {2023},
NUMBER = {2},
PAGES = {102-121},
URL = {https://www.scipublications.com/journal/index.php/WJCOR/article/view/727},
ISSN = {2831-5162},
DOI = {10.31586/wjcor.2023.727},
ABSTRACT = {Calotropis procera, a medicinally important plant found in Asia, was explored for its anticancer and antibacterial properties in this study. The leaves of C. procera were extracted using methanol and FTIR and UV-VIS spectrophotometry were used to characterize them. Using the MTT assay and the disc diffusion test, the extract was examined for anticancer activity against the MCF7 breast cancer cell line and antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). The methanolic fraction of C. procera was found to be efficient against the MCF7 cell line and dramatically suppressed MRSA growth.  The metabolic fraction of C. procera leaves is important in suppressing the growth of the MCF7 cell line, and it has the potential to be an effective antibacterial agent, according to our findings. The implications of Calotropis procera for all healthcare professionals including oncologists, physicians, pharmacists, nurses, and nutritional therapists are significant. With the increasing incidence of cancer and antibiotic-resistant bacterial infections, there is a growing need for new, effective, and safer herbal treatments.},
}
%0 Journal Article
%A Rasul, Shafqat
%A Rashid, Abid
%A Akram, Muhammad
%A Laila, Umme
%A Zainab, Rida
%A Khalil, Muhammad Talha
%A Mbaye, Hadji Seydou
%A Said, Mourad Ben
%A Alharbi, Hanan sneed
%A Alabed, Hanadi Husni
%A Shahin, Mahmoud Abdel Hameed
%D 2023
%J Current Research in Public Health

%@ 2831-5162
%V 2
%N 2
%P 102-121

%T Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review
%M doi:10.31586/wjcor.2023.727
%U https://www.scipublications.com/journal/index.php/WJCOR/article/view/727

TY  - JOUR
AU  - Rasul, Shafqat
AU  - Rashid, Abid
AU  - Akram, Muhammad
AU  - Laila, Umme
AU  - Zainab, Rida
AU  - Khalil, Muhammad Talha
AU  - Mbaye, Hadji Seydou
AU  - Said, Mourad Ben
AU  - Alharbi, Hanan sneed
AU  - Alabed, Hanadi Husni
AU  - Shahin, Mahmoud Abdel Hameed
TI  - Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review
T2  - Current Research in Public Health
PY  - 2023
VL  - 2
IS  - 2
SN  - 2831-5162
SP  - 102
EP  - 121
UR  - https://www.scipublications.com/journal/index.php/WJCOR/article/view/727
AB  - Calotropis procera, a medicinally important plant found in Asia, was explored for its anticancer and antibacterial properties in this study. The leaves of C. procera were extracted using methanol and FTIR and UV-VIS spectrophotometry were used to characterize them. Using the MTT assay and the disc diffusion test, the extract was examined for anticancer activity against the MCF7 breast cancer cell line and antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). The methanolic fraction of C. procera was found to be efficient against the MCF7 cell line and dramatically suppressed MRSA growth.  The metabolic fraction of C. procera leaves is important in suppressing the growth of the MCF7 cell line, and it has the potential to be an effective antibacterial agent, according to our findings. The implications of Calotropis procera for all healthcare professionals including oncologists, physicians, pharmacists, nurses, and nutritional therapists are significant. With the increasing incidence of cancer and antibiotic-resistant bacterial infections, there is a growing need for new, effective, and safer herbal treatments.
DO  - Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review
TI  - 10.31586/wjcor.2023.727
ER  -