Mutational Analysis of Driver and Non-driver Mutations of Philadelphia Chromosome-negative Myeloproliferative Neoplasms; Diagnosis and Recent Advances in Treatment
Figure 5.
Acquired mutations associated with MPN pathogenesis showing constitutive activation of JAK/STAT, MAPK, and PI3K/Akt pathways; driver mutations (JAK2, CALR and MPL) in red; other mutations in yellow.