Poverty Status at Birth Predicts Epigenetic Changes at Age 15
Table 4.
Summary of Structural Equation Modeling (SEM) by Sex
|
|
Coefficient |
std. err. |
[95% conf. |
interval] |
P>z |
|
|
| Females |
|
|
|
|
|
|
|
| Maternal Education at Childbirth |
|
|
|
|
|
|
|
| Ethnicity (Latino) |
-0.19 |
0.05 |
-0.30 |
-0.08 |
0.001 |
|
|
| Race (Black) |
-0.19 |
0.05 |
-0.29 |
-0.08 |
0.001 |
|
|
| Intercept |
2.42 |
0.11 |
2.21 |
2.63 |
< 0.001 |
|
|
|
|
|
|
|
|
|
|
| Income to Poverty Ratio at Childbirth |
|
|
|
|
|
|
|
| Maternal Education at Childbirth |
0.46 |
0.04 |
0.39 |
0.54 |
< 0.001 |
|
|
| Married Household at Childbirth |
0.28 |
0.04 |
0.20 |
0.36 |
< 0.001 |
|
|
| Ethnicity (Latino) |
-0.12 |
0.05 |
-0.21 |
-0.03 |
0.009 |
|
|
| Race (Black) |
-0.18 |
0.05 |
-0.27 |
-0.09 |
< 0.001 |
|
|
| Intercept |
0.04 |
0.12 |
-0.19 |
0.27 |
0.742 |
|
|
|
|
|
|
|
|
|
|
| Married Household at Childbirth |
|
|
|
|
|
|
|
| Ethnicity (Latino) |
-0.15 |
0.05 |
-0.26 |
-0.05 |
0.005 |
|
|
| Race (Black) |
-0.25 |
0.05 |
-0.35 |
-0.14 |
< 0.001 |
|
|
| Intercept |
0.85 |
0.08 |
0.68 |
1.01 |
< 0.001 |
|
|
|
|
|
|
|
|
|
|
| DNA Methylation (Age 15) |
|
|
|
|
|
|
|
| Income to Poverty Ratio at Birth |
-0.06 |
0.05 |
-0.15 |
0.03 |
0.206 |
|
|
| Intercept |
4.53 |
0.16 |
4.21 |
4.85 |
< 0.001 |
|
|
|
|
|
|
|
|
|
|
| Males |
|
|
|
|
|
|
|
| Maternal Education at Childbirth |
|
|
|
|
|
|
|
| Ethnicity (Latino) |
-0.20 |
0.05 |
-0.30 |
-0.10 |
< 0.001 |
|
|
| Race (Black) |
-0.17 |
0.05 |
-0.27 |
-0.07 |
0.001 |
|
|
| Intercept |
2.39 |
0.10 |
2.19 |
2.58 |
< 0.001 |
|
|
|
|
|
|
|
|
|
|
| Income to Poverty Ratio at Childbirth |
|
|
|
|
|
|
|
| Maternal Education at Childbirth |
0.40 |
0.04 |
0.32 |
0.49 |
< 0.001 |
|
|
| Married Household at Childbirth |
0.33 |
0.04 |
0.25 |
0.42 |
< 0.001 |
|
|
| Ethnicity (Latino) |
-0.07 |
0.04 |
-0.16 |
0.01 |
0.095 |
|
|
| Race (Black) |
-0.18 |
0.04 |
-0.26 |
-0.09 |
< 0.001 |
|
|
| Intercept |
0.10 |
0.11 |
-0.13 |
0.32 |
0.400 |
|
|
|
|
|
|
|
|
|
|
| Married Household at Childbirth |
|
|
|
|
|
|
|
| Ethnicity (Latino) |
-0.07 |
0.05 |
-0.18 |
0.03 |
0.144 |
|
|
| Race (Black) |
-0.22 |
0.05 |
-0.31 |
-0.12 |
< 0.001 |
|
|
| Intercept |
0.80 |
0.07 |
0.65 |
0.94 |
< 0.001 |
|
|
|
|
|
|
|
|
|
|
| DNA Methylation (Age 15) |
|
|
|
|
|
|
|
| Income to Poverty Ratio at Birth |
-0.13 |
0.05 |
-0.22 |
-0.04 |
0.005 |
|
|
| Intercept |
3.99 |
0.14 |
3.70 |
4.27 |
< 0.001 |
|
|
DNA methylation was measured using PhenoAge biological clock at age 15.
|
|
