Nicotinic agonists promoted the activation of nicotinic acetylcholine α7 receptors (α7 nAChR) in neurons, but failed to activate these receptors in mouse peritoneal macrophages
Figure 2.
Examples of nicotinic ionic current in rat hippocampal neurons. ACh (1 mM e 0,1 mM, A e B) and choline (1 mM e 0,1 mM, C and D) were applied with or without PNU-120596 (10 μM) in 0.5 s pulses, as indicated by the horizontal bar. Cells were maintained at a potential of - 60 mV.