Nicotinic agonists promoted the activation of nicotinic acetylcholine α7 receptors (α7 nAChR) in neurons, but failed to activate these receptors in mouse peritoneal macrophages
Figure 5.
Examples of ionic currents in RAW 264.7 cells. ACh (1 mM), ACh (0,1 mM) associated with PNU-120596 (10 μM) and ATP-Na+ (1 mM) were applied in 0.5 s pulses, as indicated by the horizontal bar. The cell was maintained at a potential of - 60 mV; representative records of 25 cells from 4 culture plates of 2 animals.