Nicotinic agonists promoted the activation of nicotinic acetylcholine α7 receptors (α7 nAChR) in neurons, but failed to activate these receptors in mouse peritoneal macrophages

Table 1.

Number of peritonealmacrophages that responded to stimulation with ATP-Na+ (1 mM) andwith ACh (1 mM) by the whole cell patch clamp technique. (+): Presence of ioniccurrent greater than basal noise.

ATP

1 mM

ACh 1 mM

+

-

+

0

38

-

0

9