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Nicotinic agonists promoted the activation of nicotinic acetylcholine α7 receptors (α7 nAChR) in neurons, but failed to activate these receptors in mouse peritoneal macrophages
Table 6.
Number of peritonealmacrophages stimulated with LPS for 24 h that responded to stimulation withATP-Na+ (1 mM), with acetylcholine (ACh; 1 mM) and with ACh andCholine (100 μM and 1 mM respectively) associated with PNU-120596 ( 10μM) using the whole cell patch clamp technique. (+): Presence of ioniccurrent greater than basal noise.