Science Publications

Sign Up
Sign In
Submit
Universal Journal of Pharmacy and Pharmacology
Download PDF XML
  1. Home
  2. Journals
  3. Universal Journal of Pharmacy and Pharmacology
  4. Archive
  5. Volume 1, Number 1, 2022
  6. Article
  7. Table 1

5-Fluorouracil Ameliorates the Hematotoxicity Induced by Cyclophosphamide in Male Albino Rats

Table 1.

WBCs, RBCs, and platelets count, Hb,and Hct of rat treated with cyclophosphamideand/or 5-fluorouracil.

Groups

Parameters

Control

CPA

5-FU

CPA – 5-FU

Mean±E

Mean±E

Mean±E

Mean±E

WBCs count (x103/µ)

13.64±.65 bcd

5.10±.50 acd

10.0±.54 abd

3.36±.63 abc

RBCs count (x106/µ)

7.57±.22 bcd

4.78±.16 acd

5.72±.38 ab

5.52±.47 ab

Hemoglobin concentration (g/dl)

14.42±.66 bcd

8.94±.40 acd

12.04±.63 abd

11.54±.53 abc

Hematocrit (%)

44.12±.15 bcd

24.96±.86 acd

34.38±.77 ab

33.66±.85 ab

Platelets count (103/μl)

910.8±4.7 bc

149.2±9.1 acd

637.6±5.7 abd

876.4±1.6 bc

Significance at P < 0.05. CPA: cyclophosphamide; 5-FU: Fluorouracil, a Comparison of control and other groups; b Comparison of CPA and other groups; c Comparison of 5-FU and other groups; d Comparison of CPA - 5-FU and other groups.
Significance at P < 0.05. CPA: cyclophosphamide; 5-FU: Fluorouracil, a Comparison of control and other groups; b Comparison of CPA and other groups; c Comparison of 5-FU and other groups; d Comparison of CPA - 5-FU and other groups.