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Universal Journal of Pharmacy and Pharmacology
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  3. Universal Journal of Pharmacy and Pharmacology
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  5. Volume 1, Number 1, 2022
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  7. Table 2

5-Fluorouracil Ameliorates the Hematotoxicity Induced by Cyclophosphamide in Male Albino Rats

Table 2.

Lymphocytes, neutrophils, eosinophils,and monocytes Count (x103/礚) of rat treated with cyclophosphamide and/or 5-fluorouracil.

Groups

Parameters

Control

CPA

5-FU

CPA – 5-FU

Mean±E

Mean±E

Mean±E

Mean±E

Lymphocytes Count (x103/µ)

6.22±.24 b

1.62±.15 acd

5.66±.58 b

6.0±.17 b

Neutrophils Count (x103/µ)

7.54±.14 bcd

2.98±.15 ad

3.06±.19 ad

4.0±.38 abc

Eosinophils Count (x103/µ)

0.56±.05 bcd

0.36±.05 ad

0.36±.05 ad

0.44±.05 abc

Monocytes Count (x103/µ)

0.46±.05 bcd

0.24±.05 acd

0.36±.02 ab

0.37±.03 ab

Significance at

Significance at P < 0.05. CPA: cyclophosphamide; 5-FU: Fluorouracil, a Comparison of control and other groups; b Comparison of CPA and other groups; c Comparison of 5-FU and other groups; d Comparison of CPA – 5-FU and other groups.