Cyclophosphamide Induces Hepatorenal Toxicity and Attenuation by 5-fluorouracil in Male Albino Rats

Table 1.

Serum total protein, albumin, and globulinconcentrations of rats treated with cyclophosphamide and/or 5-fluorouracil

Groups Parameters	Control	CPA	5-FU	CPA – 5-FU
Groups Parameters	Mean±SE	Mean±SE	Mean±SE	Mean±SE
Serum total protein concentration (g/dl)	10.01±0.73 ^bc	7.93±0.26^acd	9.32±0.36^ab	9.67±0.58^b
Serum albumin concentration (g/dl)	4.23±0.15^bd	3.39±0.61^acd	4.54±0.35^b	4.40±0.13^ab
Serum globulin concentration (g/dl)	5.82±0.17^bd	3.30±0.37^acd	4.96±0.40^ab	5.22±0.57^b

Significance at P > 0.05. CPA: cyclophosphamide; 5-FU: Fluorouracil, ^a Comparison of control and other groups; ^b Comparison of CPA and other groups_;^c Comparison of 5-FU and other groups; ^d Comparison of CPA – 5-FU and other groups

Cyclophosphamide Induces Hepatorenal Toxicity and Attenuation by 5-fluorouracil in Male Albino Rats

Table 1.

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