5-fluorouracil Improves the Testicular Antioxidant Status and Alleviates Oxidative Stress in Male Albino Rats Treated with Cyclophosphamide

Table 1.

Testis totalantioxidant, glutathione, glutathione reductase, and catalase of rat treatedwith cyclophosphamide and/or 5-fluorouracil

Groups Parameters	Control	CPA	5-FU	CPA – 5-FU
Groups Parameters	Mean±SE	Mean±SE	Mean±SE	Mean±SE
Testis total antioxidant (U/g tissue)	1.32±0.09 ^bcd	0.83±0.12^acd	1.04±0.10^ab	1.12±0.07^ab
Testis glutathione (U/g tissue)	18.05±0.97^bcd	9.62±0.75^acd	13.93±0.82^abd	11.74±0.84^abc
Testes glutathione reductase (U/g tissue)	42.10±1.57^bcd	24.91±1.86^acd	32.79±1.45^ab	33.08±1.27^ab
Testes catalase (U/tissue)	40.15±1.72^bcd	23.52±1.69^acd	32.45±1.17^abd	35.26±2.00^abc

Significance at P > 0.05. CPA: cyclophosphamide; 5-FU: Fluorouracil, ^a Comparison of control and other groups; ^b Comparison of CPA and other groups; ^c Comparison of 5-FU and other groups; ^d Comparison of CPA – 5-FU and other groups

5-fluorouracil Improves the Testicular Antioxidant Status and Alleviates Oxidative Stress in Male Albino Rats Treated with Cyclophosphamide

Table 1.

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