Depression, Subjective Health, Obesity, and Multimorbidity are Associated with Epigenetic Age Acceleration
Table 2.
Heatmap showing age and sex-adjustedassociations
|
| |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
13 |
14 |
15 |
16 |
17 |
18 |
19 |
20 |
21 |
|
|
| 1 HORVATH |
1.00 |
.43* |
.27* |
.57* |
.52* |
-.16* |
.19* |
.16* |
.06* |
-.24* |
.24* |
.06* |
.08* |
.03 |
.05* |
.03* |
.03 |
.01 |
.04* |
.03 |
.00 |
|
|
| 2 HANNUM |
|
1.00 |
.41* |
.53* |
.35* |
.13* |
.30* |
.22* |
.36* |
-.15* |
.39* |
.19* |
.07* |
.07* |
.05* |
.04* |
.01 |
-.01 |
.04* |
.08* |
.03 |
|
|
| 3 LEVINE |
|
|
1.00 |
.23* |
.33* |
.32* |
.43* |
.04* |
.38* |
-.26* |
.14* |
.35* |
.13* |
.11* |
.05* |
.07* |
.03 |
.01 |
.10* |
.13* |
.04* |
|
|
| 4 HORVATH-SKIN |
|
|
|
1.00 |
.37* |
-.09* |
.19* |
.17* |
.07* |
-.14* |
.38* |
.09* |
.08* |
.04* |
.03* |
.04* |
.03 |
.01 |
.06* |
.07 |
.04* |
|
|
| 5 LIN |
|
|
|
|
1.00 |
.13* |
.28* |
-.05* |
.09* |
-.30* |
.17* |
.06* |
.04* |
.03 |
.01 |
.03* |
.00 |
-.01 |
.03* |
.01 |
-.01 |
|
|
| 6 WEIDNER |
|
|
|
|
|
1.00 |
.52* |
.11* |
.20* |
-.06* |
.04* |
.11* |
-.01 |
.01 |
.02 |
.02 |
.00 |
-.02 |
.02 |
.02 |
.00 |
|
|
| 7 VIDALBRALO |
|
|
|
|
|
|
1.00 |
-.09* |
.35* |
-.50* |
.05* |
.25* |
.07* |
.03* |
.07* |
.04* |
.01 |
.01 |
.03* |
.05* |
.01 |
|
|
| 8 YANG |
|
|
|
|
|
|
|
1.00 |
.10* |
.22* |
.16* |
-.01 |
.01 |
.06* |
.02 |
-.02 |
.00 |
-.01 |
.03 |
.12* |
.07* |
|
|
| 9 ZHANG |
|
|
|
|
|
|
|
|
1.00 |
-.15* |
.04* |
.52* |
.17* |
.11* |
.06* |
.07* |
.08* |
.05* |
.08* |
.18* |
.10* |
|
|
| 10 BOCKLANDT |
|
|
|
|
|
|
|
|
|
1.00 |
.00 |
-.13* |
-.02 |
.01 |
-.04* |
.00 |
.00 |
-.03* |
.01 |
.01 |
.03* |
|
|
| 11 GARAGNANI |
|
|
|
|
|
|
|
|
|
|
1.00 |
.08* |
.04* |
.03 |
.02 |
.02 |
.02 |
.02 |
.02 |
.04* |
.04* |
|
|
| 12 GRIMAGE |
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.22* |
.11* |
.04* |
.09* |
.10* |
.05* |
.07* |
.23* |
.13* |
|
|
| 13 CMC n |
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.50* |
.28* |
.49* |
.33* |
.44* |
.32* |
.46* |
.29* |
|
|
| 14 Diabetes |
|
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.03* |
.11* |
.08* |
.08* |
.26* |
.28* |
.13* |
|
|
| 15 Cancer |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.06* |
.00 |
.05* |
.04* |
.05* |
-.01 |
|
|
| 16 Heart Disease |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.12* |
.09* |
.10* |
.21* |
.10* |
|
|
| 17 Stroke |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.08* |
.05* |
.16* |
.11* |
|
|
| 18 Psychiatric Conditions |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.06* |
.19* |
.33* |
|
|
| 19 BMI |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.26* |
.11* |
|
|
| 20 SRH |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
.41* |
|
|
| 21 CES-D |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1.00 |
|
|
|
|