The purpose of the study was to examine Colleges of Education students’ attitudes toward the teaching and learning of Social Studies in the Ashanti region. Quantitatively, descriptive survey research design was employed for the study to examine the attitudes of Colleges of Education students toward the teaching and learning of Social Studies in the Ashanti region. The population for the study comprised all the second year (form 2) Social Studies students from the four (4) selected Colleges of Education in the Ashanti Region. Purposive and simple random sampling techniques were used to select four (4) Colleges of Education (St. Louis, Wesley, St. Monica's and Offinso Colleges of Education), and two-hundred seventy-seven (277) second year Social Studies students for the study. The main instrument used for data collection was questionnaire. The quantitative data obtained was coded into Statistical Product for Service Solution (SPSS) (version 26.0) and analyzed using descriptive statistics involving tables, frequencies and percentages for each item. “Strongly Agree”, “Agree”, “Strongly Disagree”, “Disagree” were all used in the analysis for easy presentation and understanding. The study revealed that students were able to dedicate much time to studying the subject in order to acquire relevant knowledge, positive attitudes and skills as well as solve societal problems stems from their ability to have good perception of the subject. The study also concludes that varying techniques of teaching is a key factor in enabling students to develop keen interest in Social Studies. It arouses and sustain students’ interest in the subject, they must not neglect employing methods that are student-centered. It is recommended that teachers should vary their methods of teaching to focus more on the use of child-centered techniques of teaching. It is also recommended that, teaching universities and colleges of education should collaboration with Ministry of Education, T-TEL and other Non-governmental educational organizations to organise workshops, and seminars to help Social Studies teachers on the use of vary teaching techniques in evaluating students learning.