Race, Poverty Status at Birth, and DNA Methylation of Youth at Age 15

Table 4.

Summary of SEM by Sex

Standardized Coefficient std. err. 95% CI p

Females

Structural

DNAm Grim (k6mk_pcgrim)

Household Income to Poverty Ratio (SEP) at Birth -0.03 0.05 -0.12 0.07 0.604

Black 0.20 0.06 0.09 0.31 < 0.001

Latino 0.11 0.06 0.00 0.22 0.047

Immune Cells % 12.93 0.47 12.00 13.85 < 0.001

Household Income to Poverty Ratio (SEP) at Birth

Black -0.22 0.05 -0.32 -0.13 < 0.001

Latino -0.18 0.05 -0.27 -0.08 < 0.001

Immune Cells % 0.41 0.04 0.33 0.48 < 0.001

Intercept 1.00 0.09 0.82 1.18 < 0.001

Males

Structural

DNAm Grim (k6mk_pcgrim)

Household Income to Poverty Ratio (SEP) at Birth -0.14 0.05 -0.24 -0.05 0.003

Black 0.09 0.05 -0.02 0.19 0.093

Latino 0.00 0.05 -0.10 0.10 0.993

Immune Cells % 12.57 0.44 11.71 13.42 < 0.001


Household Income to Poverty Ratio (SEP) at Birth

Black -0.20 0.04 -0.29 -0.11 < 0.001

Latino -0.13 0.04 -0.22 -0.05 0.002

Immune Cells % 0.47 0.04 0.39 0.54 < 0.001

Intercept 0.89 0.08 0.74 1.05 < 0.001