The Future of Longevity Medicine from the Lens of Digital Therapeutics

Table 1.

Details of digital therapeutics in Longevity currently available in the market

SlNo Company Name & Country of Origin Indication Features

1 AgeX Therapeutics 16
United States
Regenerative Medicine Specializes in regenerative medicine using pluripotent stem cells. Focused on tissue engineering and cell-based therapies.
2 Altos Labs 17
UK
Cellular Rejuvenation Focuses on cellular rejuvenation programming to reverse age-related decline. High-profile team includes leading scientists and significant funding from Jeff Bezos.
3 Amazentis (Timeline) 18
Switzerland 
Mitophagy & Muscle Health Pioneers in research on mitophagy and mitochondrial health. Offers Urolithin A-based products for improving muscle and cell performance.
4 Apollo Health Ventures19
Germany
Aging Research Investment Venture capital firm targeting companies with potential breakthroughs in aging. Supports translational research to bridge science and application.
5 BioAge Labs 20
United States
Aging Biomarker Discovery Leverages human aging data to identify biomarkers and drug targets to combat aging-related diseases.
6 BioXtek21
United States
Regenerative Technology Cutting-edge platform leverages the regenerative properties of amniotic membrane and other birth-derived tissues to address various age-related conditions.
7 Calico Labs22
United States
Aging-related Therapies Backed by Google’s Alphabet, focused on understanding the biology of aging. Develops therapies targeting age-related diseases through collaboration with AbbVie.
8 Caristo Diagnostics23
Oxford, England
Cardiovascular aging AI-based tool capable of predicting heart attacks up to a decade in advance by assessing coronary inflammation. This technology provides clinicians with a powerful tool to identify at-risk individuals and implement preventive measures.
9 CHARACTER BIOSCIENCES 24
USA
Disease Progression Integrates genomics, longitudinal clinical and imaging data, machine learning, and novel experimental approaches to identify the molecular drivers of disease progression and develop innovative targeted medicines. 
10 Chromadex (Tru Niagen) 25
United States
NAD+ Mitochondrial Health Specializes in NAD+precursors to improve mitochondrial health. Products aimed at boosting energy and cellular repair.
11 Deep Longevity26
Hong Kong
AI for Biological Age Builds AI-driven models to measure biological age and predict longevity based on health and lifestyle factors.
12 Dorian Therapeutics 27
 USA
Senescence Therapies They are developing senoblockers, a new class of therapeutics with a double function: blocking senescence while reactivating the regeneration capacity of a tissue. 
13 Elysium Health28
United States
NAD+ Boosters & Aging Offers consumer-facing products like NAD+ boosters and health supplements. Develops and 12commercializes epigenetic biomarkers for aging.
14 Glycan age29
UK 
Biological Age Testing Glycan Age is a simple,  test that analyses  glycobiology. Taking a GlycanAge® test is a vital step to determine once biological age.  
15 Gero30
Singapore
Aging Biomarker Models Develops AI-driven solutions to study biomarkers of aging and resilience. Known for predictive models of healthspan.
16 Insilico Medicine 31
Hong Kong
Aging Research Combines AI with genomics to identify therapeutic targets for age-related diseases. Leader in using deep learning for drug discovery and aging research.
17 Juvenescence 32
United Kingdom
Aging-related Diseases A biotech company investing in and developing drugs to target aging and age-related conditions. Broad portfolio includes senolytics and metabolic regulators.
18 Libella Gene Therapeutics 33
United States
Telomere Lengthening Focused on telomere lengthening through gene therapy. Clinical trials for aging-related diseases are underway.
19 Life Biosciences 34
United States
Cellular Health Aging Aims to combat aging through research in epigenetics, mitochondrial health, and senescence. Focuses on restoring cellular health to extend lifespan.
20 Longevity Vision Fund 35
United States
Aging & Longevity Investment Focuses on funding startups in aging and longevity science. Invests in innovations targeting healthspan and lifespan extension.
21 MICREGEN 36
UK
Stem Cell Therapies Innovative approach in developing the Secretomix® platform to produce various secretome formulations from its first clinical grade master and working cell banks, could change how multiple critical and chronic problems are managed- not just the symptoms, but the root causes of diseases. They are primarily working on stem cells.  
22 ONE SKIN 37
USA
Skin Aging Reversal Their products focus on skin longevity. One Skin’s proprietary peptide, OS-01, is an ingredient designed to reduce skin's biological age by improving skin barrier, supporting DNA damage repair, and preventing the accumulation of aged cells. 
23 Oisín Biotechnologies 38
USA
Aging-related diseases Longevity therapeutics platform company focused on creating genetic medicines to combat a variety of age related diseases. Oisín Biotechnologies is developing a highly precise, DNA-targeted intervention to clear the senescent cells. As a recent study has shown, clearing senescent cells both reduces negative effects of aging pathologies and also extends median lifespan and survival. 
24 PULSE SIGHT 39
France
Age-related Macular Degeneration Ophthalmology drug development company developing disruptive non-viral gene therapies with minimally invasive delivery technology to treat AMD.
25 Rejuvenate Bio 40
United States
Gene Therapy Aging Utilizes gene therapy to reverse age-related conditions in animals and humans. Targeting cardiovascular and metabolic diseases.
26 SUZHOU Ruiming41
China
Age-related Macular Degeneration The company has developed an eye-drop drug delivery technology for fundus diseases which include age-related wet macular degeneration (AMD), retinal vein occlusion, and diabetic macular edema. 
27 S-Biomedic 42
Belgium
Skin Health Solutions Focused on skin health by pioneering the development of Pro- and Post-biotic ingredients from true skin commensals. 
28 SeaBeLife Biotech 43
France 
Neurodegenerative diseases Focuses on the development of molecules designed to block regulated necrosis – also known as regulated cell death.
29 Sirona Biochem Corp 44
Canada
Skin Health Solutions Developed a novel anti-aging compound designed to reverse the effects of aging on facial skin.
30 Thorne HealthTech 45
United States
Personalized Longevity Provides personalized health insights through testing kits. Focuses on nutritional solutions and longevity interventions.
31 Turn Biotechnologies 46
United States
Epigenetic Reprogramming Uses epigenetic reprogramming to restore youthful cell function. Targets applications in skin and muscle rejuvenation.
32 Unity Biotechnology 47
United States
Senolytic Therapies Focuses on eliminating senescent cells to address diseases like osteoarthritis, fibrosis, and neurodegenerative conditions.