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Journal of Cellular Neuroscience
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  5. Volume 2, Number 1, 2025
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  7. Table 2

Mean Diffusivity of the Left Caudal Anterior Cingulate Cortex and Past Major Depressive Disorder in Adolescents: Evidence from the ABCD Study

Table 2.

Bivariate Correlations (Spearman)
    MD-MRI Age Male Pubertal initiation Neighbor-hoodincome Trauma Discrimination Financial Difficulty HH Income Parental Education Married /Partnered Family MDD
Age rho -.032**                      
  p 0.006                      
Male rho -.025* .024*                    
  p 0.030 0.030                    
Pubertal Initiation rho -0.021 .133** -.092**                  
  p 0.103 0.000 0.000                  
Neighborhood Income rho .075** .050** 0.017 -.077**                
  p 0.000 0.000 0.136 0.000                
Trauma (Any) rho -0.005 0.013 -0.018 .052** -.095**              
  p 0.671 0.261 0.122 0.000 0.000              
Discrimination rho -0.006 -.027* .095** .100** -.161** .045**            
  p 0.625 0.021 0.000 0.000 0.000 0.000            
Financial difficulty (n) rho -.038** -0.005 0.010 .028* -.298** .157** .108**          
  p 0.001 0.631 0.358 0.025 0.000 0.000 0.000          
HH Income rho .083** .034** 0.003 -.064** .589** -.124** -.192** -.454**        
  p 0.000 0.004 0.778 0.000 0.000 0.000 0.000 0.000        
Highest parental education rho .067** 0.005 -0.002 -.057** .478** -.089** -.144** -.325** .597**      
  p 0.000 0.672 0.863 0.000 0.000 0.000 0.000 0.000 0.000      
Married or partnered family rho 0.011 -0.004 0.009 -.047** .272** -.125** -.114** -.256** .470** .268**    
  p 0.351 0.710 0.405 0.000 0.000 0.000 0.000 0.000 0.000 0.000    
Past MDD rho 0.009 0.013 0.012 .030* -.029* .040** .079** .057** -.047** -.032* -.033**  
  p 0.509 0.300 0.326 0.035 0.025 0.002 0.000 0.000 0.000 0.012 0.009  
Suicide Attempt rho -0.008 -0.015 0.014 .041* -.070** .047* .094** .087** -.107** -.061** -.081** .043*
  p 0.654 0.403 0.436 0.036 0.000 0.011 0.000 0.000 0.000 0.001 0.000 0.023

Note: MD-MRI = Mean diffusivity within parcellation of gray matter-white matter contrast associated with cortical ROI left-caudal anterior cingulate; Neighborhood SES: Residential history derived - Area Deprivation Index: Median family income; Past MDD: previous diagnosis of major depressive disorder.