High levels of occupational noise and vibration remain a problem in all regions of the world. In Nigeria, 12−15% of the workforce are exposed to these hazards by WHO, 2001. This research intends to achieve the following objectives; To assess the noise emitted during the moulding of various types of blocks, to determine the level of vibration induced to workers of block moulders during activities and to determine the effect of noise and vibration on workers. The following materials and equipment were used; QT40B manual block moulding machine, LM2-45 Mobile Block moulding Machine, Lister powered block moulding machine, QTJ4-40 block moulding machine using 9 and 6 inches Plates, Vibrometer and Noise monitor. The workers were exposed to noise levels above 75dB and vibration levels above 5ms-2 set as upper limit values in the Directive 44/EC from 2002 – on the Minimum Health and safety Requirements Regarding to Exposure of Workers to the Risk Arising from Physical Agents Vibration.