The present paper attempts to investigate the problem of Fault Tolerant Control for a class of uncertain neutral time delay systems. In the first time, we consider an additive control that is based on adding a term to the nominal law when the fault occurs. This approach will be designed in three steps. The first step is fault detection while the second one is fault estimation. For these two steps, we consider the adaptive observer to guarantee the detection and estimation of the fault. The third step is the fault compensation. Lyapunov method and Linear Matrix Inequality (LMI) techniques were considered to improve the main method. Second, we propose a Pseudo Inverse Method "PIM" and determine the error between the closed loop and the nominal system. Finally, simulation results are presented to prove the theoretical development for an example of an uncertain neutral time delay system.