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Case Report: Unmasking Meigs’ Syndrome and the resolution of persistent Ascites after Oophorectomy in an 18-year-old Female at Cleveland Specialized Clinic Wampewo

Global Journal of Medical Case Reports | Vol 4, Issue 1

Table 1. _Timeline">Table 1. Timeline of Patient’scare timeline

Date Event Details
February2023 Initial presentation 18-year-old female presented with severe breathlessness, gross abdominal distention due to persistent ascites, generalized weakness, and pallor.
March 2023Initial Diagnostic workupBlood tests (CBC, LFTs, RFTs), tumor markers, and imaging studies (ultrasound scan, CT scan, Echo, ECG) performed; all results were unremarkable
April 2023Repeated paracenteses, and thoracenteses Ascitic fluid drained, providing temporary relief. Ascitic fluid analysis showed transudative pattern; GeneXpert analysis for TB was Negative.
May 2023Persistent symptoms Re-accumulation of ascitic fluids within one week despite diuretic therapy and multiple presentences
June 2023Extended diagnostics investigation Additional tests conducted: Chest X-ray, ECG, echocardiogram, serological tests for infections (HIV, HBV, HBC) all Negative, histopathology report Negative
Jully 2023Specialist referral and continued monitoring Referral to a specialist; continued monitoring and symptomatic management with no significant improvement
August 2023Decision for Exploratory laparotomyDue to persistent unexplained ascites and negative findings, a decision was made to perform an exploratory laparotomy.
September 2023Continued monitoring a waiting for Fund Continued monitoring and control of ascites and pleural effusion, with diuretics and paracenteses and thoracenteses as waiting for funds
October 2023Exploratory laparotomy performed Bilateral oophorectomy and salpingectomy performed; intraoperative findings revealed bilateral ovarian tumors
November 2023Histopathology results Histopathology confirmed benign ovarian fibromas consistent with Meigs’ Syndrome; No evidence of malignancy
December 2023Postoperative recovery Patient experienced complete resolution of symptoms, with no further ascites accumulation or abdominal distension
January- February 2024Follow-up Examination 1. Follow-up visit showed stable condition, no recurrence of symptoms, normal physical examination, with maintenance small dose of diuretics
March-April 2024Second last follow-up examination Patient remained asymptomatic with no recurrence of ascites, overall clinical status was stable, and the patient resumed normal activities.
June 2024Final follow-up examination Patient withdrawn from all drugs. Patient remained asymptomatic with no recurrence of ascites.