Hippocampus Functional Connectivity, Impulsivity, and Subsequent Substance Use

Table 3. Summary of SEM

	B	SE	95%	p
Structural
Predictor		Outcome
Sex (Male)	→	Hippocampus rsFC	0.500	0.008	0.484	0.516	0.000


Hippocampus rsFC	→	Urgency	-0.015	0.024	-0.061	0.031	0.524
Age	→	Urgency	0.205	0.003	0.199	0.210	0.000
Sex (Male)	→	Urgency	0.123	0.013	0.097	0.149	0.000


Hippocampus rsFC	→	Substance Use in the Future	-0.039	0.022	-0.083	0.005	0.082
Urgency	→	Substance Use in the Future	0.052	0.017	0.019	0.084	0.002
Age	→	Substance Use in the Future	0.008	0.004	0.001	0.016	0.018
Sex (Male)	→	Substance Use in the Future	-0.012	0.013	-0.037	0.013	0.362

Measurement

Cingulo Parietal Network (Right)	→	Hippocampus rsFC	0.752	0.009	0.735	0.769	0.000
Default Mode Network (Left)	→	Hippocampus rsFC	0.465	0.009	0.448	0.482	0.000
Sensory Motor Network (Left)	→	Hippocampus rsFC	0.439	0.009	0.421	0.456	0.000
Visual Network (Left)	→	Hippocampus rsFC	0.340	0.009	0.322	0.358	0.000

Positive Urgency	→	Urgency	0.670	.006	0.659	0.681	0.000
Negative Urgency	→	Urgency	0.789	0.007	0.776	0.802	0.000

Tobacco Use	→	Substance Use in the Future	0.748	0.019	0.711	0.784	0.000
Marijuana Use	→	Substance Use in the Future	0.595	0.015	0.566	0.624	0.000