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Nicotinic agonists promoted the activation of nicotinic acetylcholine α7 receptors (α7 nAChR) in neurons, but failed to activate these receptors in mouse peritoneal macrophages
Universal Journal of Pharmacy and Pharmacology
| Vol 1, Issue 1
Table 5. Number ofperitoneal macrophages stimulated with LPS for 4 h that responded tostimulation with ATP-Na+ (1 mM) and with acetylcholine (ACh; 100μM) associated with PNU-120596 (10 μM) by the whole cell patch clamptechnique. (+): Presence of ionic current greater than basal noise.
| 1 mM | ACh 0,1 mM + PNU 10 μM | |
| + | - | |
| + | 0 | 23 |
| - | 0 | 0 |