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Drug-Receptor Interaction of Peptidic HIV-1 Protease: Intermolecular Interaction-III

Online Journal of Microbiological Research | Vol 3, Issue 1

Table 5. Classification of compounds (acid/A or base/B) withrespect to receptor amino acids

No.χDValIleNo.χDValIle


χR =4.71χR =4.88χR =4.71χR =4.88
14.97AA275.47AA
25.01AA284.97AA
35.36AA294.74AB
45.01AA304.92AA
54.98AA314.93AA
65.02AA325.16AA
75.06AA335.10AA
85.34AA345.19AA
94.94AA354.88AA
105.33AA364.96AA
114.93AA374.89AA
125.37AA384.89AA
135.03AA394.85AB
145.33AA404.90AA
154.97AA414.99AA
165.12AA424.94AA
175.33AA434.87AB
184.92AA444.95AA
194.90AA454.83AB
204.93AA464.82AB
215.02AA474.89AA
225.17AA484.80AB
234.88AA494.90AA
245.40AA504.99AA
254.84AB514.97AA
264.53BB    

χ: electronegativity, R: receptor amino acid, D stand for drug (HIV-1-PRIs), Val: valine, Ile: isoleucine, A: acid and B: base.