Back to Article
Cyclophosphamide Induces Hepatorenal Toxicity and Attenuation by 5-fluorouracil in Male Albino Rats
World Journal of Clinical Medicine Research
| Vol 2, Issue 1
Table 1. Serum total protein, albumin, and globulinconcentrations of rats treated with cyclophosphamide and/or 5-fluorouracil
| Groups Parameters | Control | CPA | 5-FU | CPA – 5-FU |
| Mean±SE | Mean±SE | Mean±SE | Mean±SE | |
| Serum total protein concentration (g/dl) | 10.01±0.73 bc | 7.93±0.26 acd | 9.32±0.36 ab | 9.67±0.58 b |
| Serum albumin concentration (g/dl) | 4.23±0.15 bd | 3.39±0.61 acd | 4.54±0.35 b | 4.40±0.13 ab |
| Serum globulin concentration (g/dl) | 5.82±0.17 bd | 3.30±0.37 acd | 4.96±0.40 ab | 5.22±0.57 b |
Significance at P > 0.05. CPA: cyclophosphamide; 5-FU: Fluorouracil, a Comparison of control and other groups; b Comparison of CPA and other groups; c Comparison of 5-FU and other groups; d Comparison of CPA – 5-FU and other groups