This work presents the results of an ethnobotanical research carried out in the territory of Serre Calabre, province of Vibo Valentia (Calabria, southern Italy). In this territory, the bond between the residents and the rural environment is still strong, because the small urban centers are placed in a predominantly agricultural and forestry environment still managed in a traditional way. The survey took place between January 2019 and July 2021. Data were collected through semi-structured interviews with locals. As many as 17 informants were interviewed and a total of 185 interviews were recorded. Plant specimens were collected under the indication of the informants and then deposited at the herbarium of the Mediterranean University of Reggio Calabria (REGGIO). The data were stored on a digital database and then statistically analyzed some synthetic indexes have also been calculated, such as Relative Frequency of Citation (RFC) and the Cultural Importance Index (CI). The investigation allowed to identify 84 taxa belonging to 39 different families, among which the most represented are Lamiaceae (23 interviews, 9 taxa), Asteraceae (22 interviews, 12 taxa). The identified taxa were prevalently cited for alimentary (46 interviews, 32 taxa) and healing (55, 27) uses. The results obtained show how the traditional knowledge about plants in the Serre Calabre area is still alive, however it is exclusive heritage of elderly people and often only in one or just a few informants. In fact, many practices are no longer in use and will not be transferred to the new generations.

The teaching-learning relationship of natural medicine is key to avoid health problems in the population; adulterations and falsifications of frequently used plants are evident. The aim of this study is to raise public awareness and to urge institutions to incorporate contents in the student's curriculum. The curricula of different educational levels are analyzed to check the level of knowledge on the use of medicinal plants, as well as some regulations on quality controls. Of the wide range of species that are consumed by the population, some are detected in which adulterations and falsifications occur, although there is no danger in some cases, such as chamomiles, if a falsification occurs when consuming the whole plant instead of the flowering tops, which is where the properties reside. In other cases, adulteration occurs, generally unintentional, but very dangerous to health, such as horsetail. For a more effective quality control, we need public awareness and highly specialized personnel, with the capacity to inspect crops, markets and companies.

Chemical solvents are commonly used to prevent microbial growth; dangerous to human health and have limited antibacterial properties. On the other hand, Nanoparticles made of metallic elements (such as copper, silver, and gold) have several uses in the field of biotechnology. Silver nanoparticles are more efficient in their antimicrobial, antibacterial, anti-inflammatory and anti-cancer properties. The current study aimed to determine the green synthesis of silver nanoparticles and their antibacterial activity from the aqueous extracts of leaves of Couroupita guianensis, Punica granatum, Vitex negundo, Cirtrus maxima. AgNPs of plant extracts were prepared using silver nitrate with the respective plant extract. Then they were characterized by FTIR analysis. The respective functional groups in the synthesized silver nanoparticles were confirmed with FTIR Spectra. The antibacterial activities of the synthesized nanoparticle extract were observed by zone of inhibition. From the results, the nanoparticles synthesized from the plants extract could pave a way to formulate a drug to treat microbial infection.