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Association Between Cystatin C and 1-Year Readmission Risk in Heart Failure Patients with or without Chronic Kidney Disease

Global Journal of Cardiovascular Diseases | Vol 5, Issue 1

Table 1. BaselineCharacteristics of the Study Population.

Variables Total (n = 889) Non-CKD (n = 639) CKD (n = 250) p
Patient characteristics        
gender, n (%)       0.016
male 384 (43.19) 260 (40.69) 124 (49.60)  
female 505 (56.81) 379 (59.31) 126 (50.40)  
age, n (%)       0.205
<80 566 (63.67) 415 (64.95) 151 (60.40)  
≥80 323 (36.33) 224 (35.05) 99 (39.60)  
BMI, kg/m2 20.55 (18.38, 23.44) 20.70 (18.34, 23.44) 20.41 (18.59, 23.48) 0.961
MAP, mmHg 93.52 ± 16.08 93.71 ± 16.45 93.02 ± 15.12 0.564
NYHA, n (%)       0.241
II 112 (12.60) 85 (13.30) 27 (10.80)  
III 461 (51.86) 337 (52.74) 124 (49.60)  
IV 316 (35.55) 217 (33.96) 99 (39.60)  
CCI score 2.0 (1.0, 3.0) 1.0 (1.0, 2.0) 3.0 (2.0, 3.0) < 0.001
Comorbidities        
COPD, n (%)       0.954
no 785 (88.30) 564 (88.26) 221 (88.40)  
yes 104 (11.70) 75 (11.74) 29 (11.60)  
diabetes, n (%)       < 0.001
no 641 (72.10) 491 (76.84) 150 (60.00)  
yes 248 (27.90) 148 (23.16) 100 (40.00)  
Laboratory values        
WBC, *109/L 7.17 ± 3.33 7.06 ± 3.10 7.47 ± 3.84 0.099
Hb, g/L 113.75 ± 24.52 115.70 ± 24.67 108.78 ± 23.44 < 0.001
PLT, *109/L 142.12 ± 64.97 139.86 ± 66.20 147.88 ± 61.47 0.098
ALB, g/L 36.86 ± 4.74 36.99 ± 4.77 36.52 ± 4.64 0.189
LDL, mmol/L 1.82 ± 0.73 1.82 ± 0.72 1.82 ± 0.75 0.985
HDL, mmol/L 1.10 ± 0.33 1.11 ± 0.32 1.09 ± 0.34 0.367
Potassium, mmol/L 4.01 ± 0.70 3.92 ± 0.65 4.25 ± 0.77 < 0.001
cystatin, mg/L 1.59 (1.26, 2.27) 1.44 (1.20, 1.89) 2.28 (1.74, 3.12) < 0.001
D.dimer, mg/L 1.23 (0.80, 1.99) 1.18 (0.76, 1.99) 1.36 (0.89, 1.99) 0.010
hsTnI, ng/ml 0.06 (0.03, 0.13) 0.06 (0.02, 0.12) 0.08 (0.04, 0.15) < 0.001
BNP, pg/ml 838.29 (311.83, 1734.42) 782.62 (288.06, 1642.82) 970.29 (380.33, 2021.05) 0.045