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Open Access April 10, 2025

Assessment of the Knowledge, Attitude, and Practice of Sokoine University Students Regarding Endocrine Disruptors Coming from Plastic Chemicals

Athuman Rashid Said, Frida Richard Mgonja

Journal of Biomedical and Life Sciences 2025, 5(1), 58-66. DOI: 10.31586/jbls.2025.1274

Abstract Objective: The knowledge, attitudes, and practices of SUA students about the use of plastics containing endocrine disruptors were investigated in this study. Methodology: A study with 150 participants was conducted to assess individuals' knowledge about endocrine disruptors, attitudes, and plastic use practices. Results: The findings indicate that the participants possessed an [...] Read more.

Objective: The knowledge, attitudes, and practices of SUA students about the use of plastics containing endocrine disruptors were investigated in this study. Methodology: A study with 150 participants was conducted to assess individuals' knowledge about endocrine disruptors, attitudes, and plastic use practices. Results: The findings indicate that the participants possessed an average degree of knowledge 50.2 ± 3.85 with the main emphasis of awareness being generic concepts rather than specific substances. Regarding the potential health impacts of endocrine-disrupting chemicals present in plastics, respondents' attitudes ranged from fair to positive, with a mean score of 3.5 ±0.09 indicating a fair attitude overall. Conclusion: It is important to practice polite behavior and increase public awareness of safe plastic disposal methods. Surprising only 38.0% of the participants mentioned that they refrain from heating their food in plastic containers to reduce their exposure to plastics. Students' practices revealed a notable dependence on plastic products despite their awareness of the concerns surrounding endocrine disruptors, as most of them reported using plastic water bottles, plastic cups, and plastic bags almost always. Additionally, only 20.7% of the respondents consistently implemented strategies to prevent exposure to endocrine-disrupting chemicals. Recommendation: The study recommended increasing the use of cleaner plastic substitutes and improving educational programs to convert information into practical actions. Policies that encourage environmentally friendly behavior and raise public awareness of safe plastic disposal techniques should be put into practice.

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Open Access January 11, 2025

Exploring LiDAR Applications for Urban Feature Detection: Leveraging AI for Enhanced Feature Extraction from LiDAR Data

Olly Harouni, Alan Forghani, Maria Rashidi, Payam Rahnamayiezekavat

World Journal of Geomatics and Geosciences 2025, 4(1), 1-11. DOI: 10.31586/wjgg.2025.1242

Abstract The integration of LiDAR and Artificial Intelligence (AI) has revolutionized feature detection in urban environments. LiDAR systems, which utilize pulsed laser emissions and reflection measurements, produce detailed 3D maps of urban landscapes. When combined with AI, this data enables accurate identification of urban features such as buildings, green spaces, and infrastructure. This synergy is [...] Read more.

The integration of LiDAR and Artificial Intelligence (AI) has revolutionized feature detection in urban environments. LiDAR systems, which utilize pulsed laser emissions and reflection measurements, produce detailed 3D maps of urban landscapes. When combined with AI, this data enables accurate identification of urban features such as buildings, green spaces, and infrastructure. This synergy is crucial for enhancing urban development, environmental monitoring, and advancing smart city governance. LiDAR, known for its high-resolution 3D data capture capabilities, paired with AI, particularly deep learning algorithms, facilitates advanced analysis and interpretation of urban areas. This combination supports precise mapping, real-time monitoring, and predictive modeling of urban growth and infrastructure. For instance, AI can process LiDAR data to identify patterns and anomalies, aiding in traffic management, environmental oversight, and infrastructure maintenance. These advancements not only improve urban living conditions but also contribute to sustainable development by optimizing resource use and reducing environmental impacts. Furthermore, AI-enhanced LiDAR is pivotal in advancing autonomous navigation and sophisticated spatial analysis, marking a significant step forward in urban management and evaluation. The reviewed paper highlights the geometric properties of LiDAR data, derived from spatial point positioning, and underscores the effectiveness of machine learning algorithms in object extraction from point clouds. The study also covers concepts related to LiDAR imaging, feature selection methods, and the identification of outliers in LiDAR point clouds. Findings demonstrate that AI algorithms, especially deep learning models, excel in analyzing high-resolution 3D LiDAR data for accurate urban feature identification and classification. These models leverage extensive datasets to detect patterns and anomalies, improving the detection of buildings, roads, vegetation, and other elements. Automating feature extraction with AI minimizes the need for manual analysis, thereby enhancing urban planning and management efficiency. Additionally, AI methods continually improve with more data, leading to increasingly precise feature detection. The results indicate that the pulse emitted by continuous wave LiDAR sensors changes when encountering obstacles, causing discrepancies in measured physical parameters.

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Open Access April 29, 2024

Floristic composition of vascular epiphytes in a disturbed forest of the Douala- Edea National Park (Cameroon)

Jacques Bruno Ngotta Biyon, Constant Borel Kenfack, Seraphine Ebenye Mokake, Danielle Magloire Bell, Jean Lagarde Betti

Research Journal of Ecology and Environmental Sciences 2024, 4(1), 29-42. DOI: 10.31586/rjees.2024.701

Abstract The Douala-Edea National Park is a coastal protected area that opens to the Atlantic Ocean, and contains an abundant wildlife which finds a privilege habitat there, and certain taxa such as epiphytes, which are of particular interest for conservation. In many tropical forests, vascular epiphytes are one of the richest taxa, with major impacts on the nutrient and hydrological cycles. The aim of this research was to study the effect of the disturbance of habitat on the floristic composition of vascular epiphytes in the Douala-Edea National Park. This study was carried out between January - April 2021 in three types of disturbed habitats at the northern part of the park. Three plots of 100 m × 100 m dimensions were laid out across three ecosystems along the Sanaga river. The sampling method consisted in the direct observation of five adjacent transects of 100 m x 20 m dimensions inside each plot. Epiphytes species were evaluated on all trees of DBH ≥10 cm. Epiphytes' life-forms and the position on the host trees occupied by the epiphytes were also recorded. A total of 18 species belonging to 16 genera and 13 families were identified. Culcasia sp. was the most common species with a relative frequency of 30.27%. Biological indicators were represented by Ferns, with four species, and Orchidaceae, with one species. [...] Read more.

The Douala-Edea National Park is a coastal protected area that opens to the Atlantic Ocean, and contains an abundant wildlife which finds a privilege habitat there, and certain taxa such as epiphytes, which are of particular interest for conservation. In many tropical forests, vascular epiphytes are one of the richest taxa, with major impacts on the nutrient and hydrological cycles. The aim of this research was to study the effect of the disturbance of habitat on the floristic composition of vascular epiphytes in the Douala-Edea National Park. This study was carried out between January - April 2021 in three types of disturbed habitats at the northern part of the park. Three plots of 100 m × 100 m dimensions were laid out across three ecosystems along the Sanaga river. The sampling method consisted in the direct observation of five adjacent transects of 100 m x 20 m dimensions inside each plot. Epiphytes species were evaluated on all trees of DBH ≥10 cm. Epiphytes' life-forms and the position on the host trees occupied by the epiphytes were also recorded. A total of 18 species belonging to 16 genera and 13 families were identified. Culcasia sp. was the most common species with a relative frequency of 30.27%. Biological indicators were represented by Ferns, with four species, and Orchidaceae, with one species. The epiphytes species richness was highest in the low disturbed habitat (13 species), and lowest in the highly disturbed habitat (8 species). Strict epiphytes were highly recorded in the low disturbed habitat (6 species), and were absent in the highly disturbed habitat. Hemi-epiphytes were the commonest life-form (12 species) in the highly disturbed habitat, and have been defined as indicators of the perturbation of the habitat. Canopy was mostly sollicitated by epiphytes in the low disturbed habitat (66.25%) than the moderate disturbed habitat (49.85%), and highly disturbed habitat (30.66%). It has been found that the different forest sites have an influence on the typology of epiphytic species, and therefore, epiphytic flora should be managed for the conservation of the biodiversity in tropical forests.

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Article

Open Access October 07, 2023

A Systematic Review of Observational Studies Focusing on Impact of Telehealth Consultation in Osteoporosis Management during the Pandemic

Samia Amin, Oishi Barua, Farjana Masud ; Sumaiya Monjur, Tahsin Munajja, Ashish Joshi

Current Research in Public Health 2023, 3(2), 119-127. DOI: 10.31586/crph.2023.768

Abstract Background: The COVID-19 pandemic disrupted routine osteoporosis care due to clinic closures and limited in-person consultations. Telehealth emerged as an alternative model enabling remote care delivery and monitoring. However, previous reviews on telehealth either did not include the pandemic period or had a limited focus in scope. Evidence synthesized specifically for osteoporosis care [...] Read more.

Background: The COVID-19 pandemic disrupted routine osteoporosis care due to clinic closures and limited in-person consultations. Telehealth emerged as an alternative model enabling remote care delivery and monitoring. However, previous reviews on telehealth either did not include the pandemic period or had a limited focus in scope. Evidence synthesized specifically for osteoporosis care during the pandemic is needed but lacking. Methods: We systematically searched PubMed, MEDLINE, EMBASE, PsycINFO, Web of Science, and CINAHL for studies on telehealth for osteoporosis published between January 2021 and March 2023. Five studies met the inclusion criteria of: osteoporosis population, telehealth intervention, and COVID-19 pandemic timeframe. Data was extracted on study characteristics, COVID-19 outcomes, osteoporosis status, telehealth purpose, patient satisfaction, and clinical outcomes. Result: The five studies showed telehealth was used for monitoring data, delivering test results, adjusting medications, and assessments. Osteoporosis prevalence among telehealth users ranged 30-100%. High patient satisfaction was reported with telehealth versus in-person care. No major differences occurred in medication delays or fractures between telehealth and in-person groups. Conclusion: This review found telehealth enables effective osteoporosis care and monitoring during the pandemic, with high patient and provider satisfaction. However, more robust randomized controlled trials are needed to establish stronger evidence around telehealth's impacts on clinical osteoporosis outcomes. Implications: Though promising, further high-quality studies will help clarify telehealth's role in improving osteoporosis care and outcomes. Findings inform guidelines on integrating telehealth into routine management. Evidence on user perspectives optimizes telehealth implementation policies.

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Systematic Review

Open Access February 04, 2023

A framework for evaluation of improvement opportunities for environmental impacts on construction works using life cycle assessment and value stream mapping concepts: offsite and onsite building construction

Adekunle Mofolasayo

World Journal of Civil Engineering and Architecture 2023, 2(1), 32-57. DOI: 10.31586/wjcea.2023.562

Abstract There have been various concerns about the environmental impact of construction works. This generates a need to take a more proactive approach in evaluating the environmental impacts of construction operations and further explore ways to reduce the environmental impacts. Enormous opportunities exist within the building industry to achieve a reduction in greenhouse gas emissions. The aim of the [...] Read more.

There have been various concerns about the environmental impact of construction works. This generates a need to take a more proactive approach in evaluating the environmental impacts of construction operations and further explore ways to reduce the environmental impacts. Enormous opportunities exist within the building industry to achieve a reduction in greenhouse gas emissions. The aim of the study is to develop a framework for the evaluation of improvement opportunities for environmental impact for onsite and offsite building construction works using life cycle assessment (LCA) and value-stream-mapping concepts. Various tools for LCA exist; however, there is a need for the development of an LCA framework and improvement opportunities that can be localized to various communities to evaluate improvement opportunities for building construction. This study conducts a review of methods to evaluate the LCA of buildings on local construction sites. A procedure for establishing improvement opportunities is also developed. Based on the author’s knowledge and experience, including site visits, using value stream mapping (VSM) techniques, a conceptual framework of the present state map and future state map of residential construction works was developed. The study presents a procedure for the evaluation of improvement opportunities for the environmental impacts of construction operations.

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Article

Open Access January 28, 2023

A framework for the evaluation of the decision between onsite and offsite construction using life cycle analysis (LCA) concepts and system dynamics modeling

Adekunle Mofolasayo

World Journal of Civil Engineering and Architecture 2023, 2(1), 1-31. DOI: 10.31586/wjcea.2023.569

Abstract The decision to choose between onsite and offsite construction is important in the effort toward sustainable construction. Offsite construction is often promoted as an environmentally friendly approach to construction operations. However, previous studies have shown that there is a lack of clarity on the environmental trade-offs between onsite and offsite construction. Factors that can affect the [...] Read more.

The decision to choose between onsite and offsite construction is important in the effort toward sustainable construction. Offsite construction is often promoted as an environmentally friendly approach to construction operations. However, previous studies have shown that there is a lack of clarity on the environmental trade-offs between onsite and offsite construction. Factors that can affect the decision to build onsite or offsite include the availability of a local offsite manufacturing facility, the distance of the offsite factory to the final place of use, the proximity of the site to the local supply of material and labor, etc. This study provides a framework to apply the system dynamic modeling technique to evaluate how various factors can affect the environmental impact of the building construction phase (for onsite or offsite construction methods). The system dynamic model (using Vensim software) that was developed provides a platform that allows users to input variables such as the distance that is expected for transportation of labor, material, and equipment to both the onsite facility and the offsite construction location, factors associated with the use of equipment for construction, the distance needed for transportation of building panels or modules from the offsite facility to the final site, etc. Among other things, the model showed that an increase in the distance from the offsite yard to the final construction site increases the total impacts of transportation of completed modules. An increase in the number of trips for the transportation of material to the onsite construction location increases the total impact of onsite construction. In terms of the environmental impact of construction, none of the two methods of construction gives an absolute superiority over the other. The environmental performance of offsite and onsite depends on various associated factors. It is recommended that building practitioners review various factors that are peculiar to their projects to make an informed decision on the best construction methods.

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Open Access January 06, 2023

False Beliefs about Contracting Avian (Bird) Flu from Processed Poultry Products

Verlin B. Hinsz

Current Research in Public Health 2023, 3(1), 1-9. DOI: 10.31586/crph.2023.535

Abstract Avian influenza (bird flu) occurs sporadically in American poultry flocks, decimating these flocks and causing substantial economic losses. Avian influenza also impacts the beliefs of food handlers and preparers in the home (home cooks). Although those who properly handle and prepare processed poultry products cannot succumb to avian influenza, there is a widespread belief that one can contract [...] Read more.

Avian influenza (bird flu) occurs sporadically in American poultry flocks, decimating these flocks and causing substantial economic losses. Avian influenza also impacts the beliefs of food handlers and preparers in the home (home cooks). Although those who properly handle and prepare processed poultry products cannot succumb to avian influenza, there is a widespread belief that one can contract the bird flu from these foods. Beliefs about getting avian influenza from poultry products and intentions to avoid consuming poultry products are the focus of this study of 285 home cooks. False beliefs about getting avian influenza from handling, preparing, and consuming poultry products are apparent in this sample. Correlational analysis also shows that those holding the false beliefs intend to act upon those beliefs by planning not to consume poultry products. Moreover, the false beliefs about contracting avian influenza from poultry products are correlated with a bias to see oneself as less likely to produce food that contains foodborne diseases. These findings are consistent with, and contribute to, the research literatures on belief formation and change, behavioral intentions, and with research showing how guilt by association thought processes underlie false beliefs related to food safety. This research has important implications for poultry and other food processing industries, and for campaigns to persuade the public about real and imaginary risks associated with particular food products.

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Open Access November 29, 2022

The Application of Machine Learning in the Corona Era, With an Emphasis on Economic Concepts and Sustainable Development Goals

Milad Shahvaroughi Farahani, Amirhossein Esfahani, Fardin Alipoor

International Journal of Mathematical, Engineering, Biological and Applied Computing 2022, 1(2), 95-149. DOI: 10.31586/ijmebac.2022.519

Abstract The aim of this article is to examine the impacts of Coronavirus Disease -19 (Covid-19) vaccines on economic condition and sustainable development goals. In other words, we are going to study the economic condition during Covid19. We have studied the economic costs of pandemic, benefits in terms of gross domestic product (GDP), public finances and employment, investment on vaccines around the [...] Read more.

The aim of this article is to examine the impacts of Coronavirus Disease -19 (Covid-19) vaccines on economic condition and sustainable development goals. In other words, we are going to study the economic condition during Covid19. We have studied the economic costs of pandemic, benefits in terms of gross domestic product (GDP), public finances and employment, investment on vaccines around the world, progress and totally the economic impacts of vaccines and the impacts of emerging markets (EM) on achieving sustainable development goals (SDGs), including no poverty, good health and well-being, zero hunger, reduced inequality etc. The importance of emerging economies in reducing the harmful effects of the Corona has also been noted. We have tried to do experimental results and forecast daily new death cases from Feb-2020 to Aug-2021 in Iran using Artificial Neural Network (ANN) and Beetle Antennae Search (BAS) algorithm as a case study with econometric models and regression analysis. The findings show that Covid19 has had devastating economic and health effects on the world, and the vaccine can be very helpful in eliminating these effects specially in long-term. We observed that there is inequality in the distribution of Corona vaccines in rich countries compared to poor which EM can decrease the gap between them. The results show that both models (i.e., Artificial intelligence (AI) and econometric models) almost have the same results but AI optimization models can robust the model and prediction. The main contribution of this article is that we have surveyed the impacts of vaccination from socio-economic viewpoint not just report some facts and truth. We have surveyed the impacts of vaccines on sustainable development goals and the role of EM in achieving SDGs. In addition to using the theoretical framework, we have also used quantitative and empirical results that have rarely been seen in other articles.

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Open Access November 14, 2022

A Comparison of Life Cycle Impact of Mass Timber and Concrete in Building Construction

Adekunle Mofolasayo

World Journal of Civil Engineering and Architecture 2022, 1(1), 47-72. DOI: 10.31586/wjcea.2022.449

Abstract Life cycle assessment, LCA is one of the tools that is used to measure the environmental impacts of a process or an operation. Various studies have mentioned the benefits of mass timber in building construction. This study presents an evaluation of the LCA of certain mass timber in relation to concrete-based materials. Using Athena impact estimator for buildings, the study compared the results of [...] Read more.

Life cycle assessment, LCA is one of the tools that is used to measure the environmental impacts of a process or an operation. Various studies have mentioned the benefits of mass timber in building construction. This study presents an evaluation of the LCA of certain mass timber in relation to concrete-based materials. Using Athena impact estimator for buildings, the study compared the results of an LCA study for a house that is designed with concrete beams, concrete columns, and concrete walls with brick in the envelope category (Material group 1) with those that are made with glulam beams, glulam columns, CLT walls with spruce wood bevel siding (Material group 2), and another building with LVL columns, LVL beams, CLT walls with spruce wood bevel siding (Material group 3). The results are in line with those that were reported by the majority of previous researchers. For the location that is being reviewed (Calgary, Alberta), the designs showed that construction with wood materials having mass timber components will have a better environmental performance than that for a building design with more concrete-based materials. The building design with more concrete-based material (group 1) showed 242% and 60% higher global warming and acidification potential respectively than the building with glulam beams and columns (material group 2). Except for ozone depletion potential, material group 2 (with glulam beams and columns) has a lower impact than material group 3 (with LVL/PSL beams and columns). The differences in impacts are more pronounced when the comparison is with design with more concrete-based products. This report further shows that LCA can be helpful during the preliminary design to evaluate the expected environmental impacts of the choice of different materials. This study recommends that material manufacturers and building contractors pay attention to LCA results to evaluate areas for continuous improvement.

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Article

Open Access September 01, 2022

Public Perspective on the Negative Impacts of Substance Use-Related Social Media Content on Adolescents: A Survey

Stevie A. Burke, Alayne Mahoney, Ammara Akhtar, Allen Hammer

Open Journal of Psychology 2022, 2(2), 77-83. DOI: 10.31586/ojp.2022.378

Abstract Despite the pervasive nature of internet use among adolescents and young adults, there is not enough knowledge about whether and how involvement in social media influences substance use patterns and the risk of drug use-related problems. This study was conducted to examine the complex relationship between substance use-related social media engagement (viewing, liking, commenting, and posting the [...] Read more.

Despite the pervasive nature of internet use among adolescents and young adults, there is not enough knowledge about whether and how involvement in social media influences substance use patterns and the risk of drug use-related problems. This study was conducted to examine the complex relationship between substance use-related social media engagement (viewing, liking, commenting, and posting the substance use-related social media content) and the drug use-related problem in adolescents from public perception. We surveyed to determine the perception of social media users regarding the association between substance use-related social media content and substance/drug abuse problems. An anonymous online questionnaire was conducted to collect the response from each participant. The response was generated after collecting the data from 126 users of mixed ages. The data was stringently analyzed, and the response was displayed in the form of bar charts. The primary findings indicated a significant relationship between drug/alcohol-related social media engagement and drug/alcohol-related problems. From public perception, a positive correlation was found between the engagement in the drug use-related content and drug use associated problems. However, further research is needed to determine the right direction of these associations that can provide substantiative solutions for numerous interventions aiming to prevent drug use-related adverse consequences.

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Discussion

Open Access June 16, 2021

Impact of Pandemic Covid-19 on Higher Education-Indian Context

Pradip Kumar Das

Universal Journal of Business and Management 2021, 1(1), 13-21. DOI: 10.31586/ujbm.2021.010102

Abstract Education stratum of India as well as world are worst-hit by Covid-19 and has imposed lockdown originating deleterious effect on academic life. A sheer number of learners ceased moving educational institutions and all pedagogies halted in India. Catastrophe has behaved as a stimulant for the educational institutions to cultivate and choose for platforms with technologies which were previously [...] Read more.

Education stratum of India as well as world are worst-hit by Covid-19 and has imposed lockdown originating deleterious effect on academic life. A sheer number of learners ceased moving educational institutions and all pedagogies halted in India. Catastrophe has behaved as a stimulant for the educational institutions to cultivate and choose for platforms with technologies which were previously noviced. Education sector has been challenging to weather the crux with alternative strategy and digitizing the challenges to hoover the menaces of the pandemic. Hypothesis of digital study has prognosis to impact the ventures of higher education for eon. Findings evince that despite digital learning is a nice adventure for little skills, varying illiberalities partake. Learners are crunched and academy also exclusively in unstable job. It has yet to be established the scope whereupon digital study would climactically cover for conventional study. Covid-19 conundrum has divulged prefacing dilemma and disparities clamoring synergetic attempt to contemplate even so pandemic’s approach. This deliberate paper illuminates sparse impeccable education in India and has discussed the positive and negative impacts of Covid-19. The paper also contributes a methodical substantiation of the experience and lessons digested from the impact of the pandemic on the transitional education panorama, and the dissemination and acceptance of e-learning in education. To end, few suggestions along with policy recommendations have been made to meet didactics during the pandemic contingency.

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Open Access June 26, 2025

The Intersection of Climate Change Adaptation and Smallholder Farmer Food Security: A Review of Strategies and Barriers

Eric Strandt

Universal Journal of Food Security 2025, 2(1), 13-29. DOI: 10.31586/ujfs.2025.6126

Abstract Smallholder farmers play a pivotal role in global food security; however, they remain exceptionally vulnerable to the impacts of climate change due to their reliance on natural resources and limited adaptive capacities. This narrative review synthesizes a wide range of global sources to explore the intersection of smallholder agriculture and climate adaptation strategies. The review examines [...] Read more.

Smallholder farmers play a pivotal role in global food security; however, they remain exceptionally vulnerable to the impacts of climate change due to their reliance on natural resources and limited adaptive capacities. This narrative review synthesizes a wide range of global sources to explore the intersection of smallholder agriculture and climate adaptation strategies. The review examines adaptation practices, agroecological methods, and the adoption of climate-resilient crop varieties. It reveals that the implementation of these strategies is frequently hindered by systemic barriers such as financial constraints, limited technological access, and institutional inefficiencies. Recognizing that previous studies have addressed isolated aspects of adaptation or relied on secondary data, this review highlights research gaps and offers a comprehensive synthesis of relevant literature. This review uses a narrative synthesis model suitable for integrating evidence from agronomy, economics, and social science to capture the complex challenges faced by smallholder farmers. The review emphasizes the importance of policy frameworks and participatory approaches that empower smallholder communities. This review synthesizes current evidence to inform potential directions for targeted interventions and future field-based studies, while recognizing the limitations of relying on secondary data. These recommendations aim to facilitate integrated policy reforms and drive research initiatives, ultimately strengthening the resilience and adaptability of smallholder agriculture in the face of ongoing climate change.

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Review Article

Open Access February 10, 2025

Higher-than Expected Social Security Reliance Among Educated Black Americans: Minorities' Diminished Returns in National Health Interview Survey (NHIS) 2023

Shervin Assari, Amanda Sonnega, Babak Najand, Hossein Zare

Journal of Biomedical and Life Sciences 2025, 5(1), 14-29. DOI: 10.31586/jbls.2025.1145

Abstract Background: While educational attainment is generally associated with reduced reliance on Social Security and disability benefits, Minorities' Diminished Returns (MDRs) theory suggests that the socioeconomic benefits of educational attainment are not equally distributed across racial groups and are weaker for minoritized populations. This study explores the association between educational [...] Read more.

Background: While educational attainment is generally associated with reduced reliance on Social Security and disability benefits, Minorities' Diminished Returns (MDRs) theory suggests that the socioeconomic benefits of educational attainment are not equally distributed across racial groups and are weaker for minoritized populations. This study explores the association between educational attainment and reliance on Social Security and disability benefits among Black and White adults in the United States. Objective: Building on the MDRs framework, we analyzed data from the National Health Interview Survey (NHIS) 2023 to examine how educational attainment impacts reliance on Social Security disability income, disability benefits, and public assistance for Black and White adults. Methods: We used a nationally representative sample of Black and White adults from the NHIS 2023 dataset. The outcomes assessed were reliance on three income sources: (1) Social Security disability income, (2) disability benefit income, and (3) public assistance disability income. Educational attainment was classified into three levels: less than high school (reference), high school diploma to some college, and college graduate or more. Logistic regression models assessed the relationship between educational attainment and reliance on each income source, with separate analyses for Black and White adults to evaluate differential effects. Results: Higher levels of educational attainment (high school diploma to some college and college graduate or more) were associated with lower odds of relying on Social Security disability, disability benefits, and public assistance. However, the protective effects of educational attainment were notably stronger for White adults than for Black adults. Among Black adults, even high educational attainment showed limited effectiveness in reducing reliance on these income sources, underscoring the Minorities' Diminished Returns (MDRs) phenomenon. Conclusions: Although educational attainment reduces reliance on Social Security and disability-related income sources, these protective effects are less pronounced for Black adults compared to White adults. The findings reveal persistent racial disparities in the economic returns of education, suggesting that structural factors may undermine the socioeconomic and health benefits of educational achievement for Black Americans. Targeted policy interventions may be needed to improve economic stability for Black adults, including those with higher educational credentials.

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Open Access February 10, 2025

Diminished Returns of Educational Attainment on Welfare Receipt of American Indian/Alaska Native People: National Health Interview Survey (NHIS) 2023

Shervin Assari, Amanda Sonnega, Hossein Zare

Open Journal of Psychology 2025, 5(1), 12-23. DOI: 10.31586/ojp.2025.1149

Abstract Background: Educational attainment is generally associated with reduced reliance on Social Security and disability benefits; however, the Minorities' Diminished Returns (MDRs) theory suggests that the socioeconomic benefits of education are weaker for minoritized populations. This study investigates the relationship between educational attainment and welfare receipt among American [...] Read more.

Background: Educational attainment is generally associated with reduced reliance on Social Security and disability benefits; however, the Minorities' Diminished Returns (MDRs) theory suggests that the socioeconomic benefits of education are weaker for minoritized populations. This study investigates the relationship between educational attainment and welfare receipt among American Indian/Alaska Native (AIAN) and White adults in the United States. Objective: Using the MDRs framework, we analyzed data from the National Health Interview Survey (NHIS) 2023 to examine how educational attainment impacts welfare receipt among AIAN and White adults. Methods: We analyzed a nationally representative sample of AIAN and White adults from the NHIS 2023 dataset. Welfare receipt was assessed as the receipt of any public assistance or welfare payments from state or local welfare offices. Educational attainment was categorized into three levels: less than high school (reference), high school diploma to some college, and college degree or higher. Logistic regression models were used to assess the relationship between educational attainment and welfare receipt, with separate analyses for AIAN and White adults to evaluate differential effects. Results: Higher educational attainment (high school diploma to some college and college degree or higher) was associated with lower odds of welfare receipt across both groups. However, the protective effect of a college degree was significantly weaker for AIAN adults compared to White adults. Consequently, AIAN adults remain at a higher risk of welfare reliance even with higher education, consistent with the Minorities' Diminished Returns (MDRs) framework. Conclusions: Although educational attainment generally reduces welfare reliance, this protection is less pronounced for AIAN adults than for White adults. This discrepancy suggests that structural factors, segregation, and social stratification may undermine the economic and health benefits of education for racialized groups in the U.S. Addressing these disparities requires policy interventions that extend beyond education, emphasizing quality job opportunities, healthcare access, and reduced labor market discrimination for individuals with advanced educational credentials, regardless of race.

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Open Access November 21, 2024

Financial Strain Partially Explains Diminished Returns of Parental Education in the ABCD Study

Shervin Assari, Hossein Zare

Open Journal of Neuroscience 2024, 2(1), 25-34. DOI: 10.31586/ojn.2024.1129

Abstract Background: Previous research shows that socioeconomic status (SES) positively impacts children's development, yet the benefits are not equally distributed across racial groups. According to the Minorities’ Diminished Returns (MDRs) framework, Black children tend to experience smaller gains from parental education compared to White children. Objective: Building on the MDRs framework, [...] Read more.

Background: Previous research shows that socioeconomic status (SES) positively impacts children's development, yet the benefits are not equally distributed across racial groups. According to the Minorities’ Diminished Returns (MDRs) framework, Black children tend to experience smaller gains from parental education compared to White children. Objective: Building on the MDRs framework, this study examines whether high financial strain contributes to the diminished returns of parental education for Black children, using data from the Adolescent Brain Cognitive Development (ABCD) Study. We hypothesized that: (1) there would be a positive effect of parental education on total cortical volume, (2) this effect would be weaker for Black than White children, and (3) higher household financial strain in Black families would mediate the diminished returns of parental education on total cortical volume for Black children. Methods: Data were drawn from the baseline ABCD Study, focusing on 7,936 9- and 10-year-old children identified as either Black (n = 1,775) or White (n = 6,161). Parental education was the key independent variable, covariates included age, sex, household income, and marital status, race was the moderator, financial strain was the mediator, and total cortical volume was the outcome. Structural Equation Models (SEMs) were employed to examine the associations between parental education and cortical volume, with financial strain as a mediator and race as a moderator. Results: Higher parental education was associated with greater cortical volume in the pooled sample. However, this effect was significantly weaker for Black children. Financial strain partially mediated the observed diminished returns of parental education. Conclusion: High financial strain experienced by middle-class Black families partially explains why the association between parental education and child development is weaker in Black than White families. Interventions aimed at enhancing educational quality, increasing employability, expanding access to higher-paying jobs, and reducing labor market discrimination against Black individuals may help address racial inequities in child development in the U.S. Efforts to reduce financial strain should extend beyond low-income populations to also support higher-educated minority families.

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Open Access November 01, 2024

Impacts of Drug Shortages in the Pharmaceutical Supply Chain

Sourav Adak

Universal Journal of Pharmacy and Pharmacology 2024, 3(1), 22-26. DOI: 10.31586/ujpp.2024.1136

Abstract Drug shortages represent a significant and growing challenge within the pharmaceutical supply chain, with profound implications for patient care, public health, and healthcare costs. This manuscript provides a comprehensive examination of the causes and impacts of drug shortages, highlighting the multifaceted nature of this issue. Key factors contributing to shortages include manufacturing [...] Read more.

Drug shortages represent a significant and growing challenge within the pharmaceutical supply chain, with profound implications for patient care, public health, and healthcare costs. This manuscript provides a comprehensive examination of the causes and impacts of drug shortages, highlighting the multifaceted nature of this issue. Key factors contributing to shortages include manufacturing complications, limited availability of active pharmaceutical ingredients (APIs), market dynamics that discourage the production of less profitable medications, and regulatory challenges that slow down the approval process for new manufacturing capacities. The consequences of these shortages are far-reaching. Patients often face treatment delays, which can lead to adverse health outcomes, increased hospitalization rates, and even mortality. Healthcare providers experience heightened operational costs as they seek alternative therapies and manage complications resulting from inadequate treatment. Furthermore, the frequent occurrence of drug shortages erodes public trust in both the healthcare system and the pharmaceutical industry, leading to decreased patient adherence to prescribed therapies. To mitigate the impacts of drug shortages, this manuscript proposes several strategic solutions, including enhanced communication among stakeholders, diversification of supply sources, increased regulatory flexibility, and collaborative approaches between public and private sectors. Additionally, raising awareness among healthcare providers and patients regarding the causes and potential alternatives can empower stakeholders to navigate shortages effectively. Ultimately, addressing drug shortages necessitates a proactive and coordinated effort from all participants in the pharmaceutical supply chain. By implementing these strategies, stakeholders can enhance the resilience of the supply chain, ensuring that essential medications remain accessible and that patient care is not compromised. The findings of this manuscript underscore the urgent need for ongoing vigilance and collaborative action to tackle the challenges posed by drug shortages, safeguarding public health and improving healthcare outcomes globally.

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Open Access October 19, 2024

Quantitative Intersectionality Scoring System (QISS): Opportunities for Enhancing Predictive Modeling, Comparative Analysis, Health Needs Assessment, and Policy Evaluation

Shervin Assari, Hossein Zare

Journal of Social Mathematical & Human Engineering Sciences 2024, 3(1), 49-61. DOI: 10.31586/jsmhes.2024.1066

Abstract Intersectionality has significantly enhanced our understanding of how overlapping social identities—such as race, ethnicity, gender, sex, class, and sexual orientation—interact to shape individual experiences. However, despite its theoretical importance, much of the existing literature has relied on qualitative approaches to define and study intersectionality, limiting its application in [...] Read more.

Intersectionality has significantly enhanced our understanding of how overlapping social identities—such as race, ethnicity, gender, sex, class, and sexual orientation—interact to shape individual experiences. However, despite its theoretical importance, much of the existing literature has relied on qualitative approaches to define and study intersectionality, limiting its application in predictive modeling, comparative analysis, and policy development. This paper introduces the concept of Quantitative Intersectionality Scoring System (QISS), a novel approach that assigns numerical scores to intersecting identities, thereby enabling a more systematic and data-driven analysis of intersectional effects. We argue that QISS can substantially enhance the utility and predictive validity of quantitative models by capturing the complexities of multiple, overlapping social determinants. By presenting concrete examples, such as the varying impacts of socioeconomic mobility on life expectancy among different intersectional groups, we demonstrate how QISS can yield more precise and reliable forecasts. Such a shift would allow policymakers and service providers to dynamically assess economic and health needs, as well as the uncertainties around them, as individuals move through different social and economic contexts. QISS-based models could be more responsive to the complexities of intersecting identities, allowing for a more quantified and nuanced evaluation of policy interventions. We conclude by discussing the challenges of implementing QISS and emphasizing the need for further research to validate these quantifications using robust quantitative methods. Ultimately, adopting QISS has the potential to improve the accuracy of predictive models and the effectiveness of policies aimed at promoting social justice and health equity.

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Open Access August 18, 2024

Extreme Heat Exposure Is Associated with Higher Socioeconomic Disadvantage and Elevated Youth Delinquency

Shervin Assari, Hossein Zare

Journal of Social Mathematical & Human Engineering Sciences 2024, 3(1), 15-28. DOI: 10.31586/jsmhes.2024.1044

Abstract Background: Climate change has led to an increase in the frequency and intensity of extreme heat events, a trend expected to continue. This poses significant health risks, particularly for vulnerable populations like children. While previous research has largely concentrated on the physical health impacts of extreme heat, less attention has been given to behavioral outcomes, such as [...] Read more.

Background: Climate change has led to an increase in the frequency and intensity of extreme heat events, a trend expected to continue. This poses significant health risks, particularly for vulnerable populations like children. While previous research has largely concentrated on the physical health impacts of extreme heat, less attention has been given to behavioral outcomes, such as delinquency. Objectives: This study investigates the association between extreme heat exposure and delinquency among children, utilizing data from the Adolescent Brain Cognitive Development (ABCD) study. It also explores the potential mediating roles of neighborhood socioeconomic status (SES; measured by median home value), puberty, peer deviance, and financial difficulties. Methods: Data from the national ABCD study were analyzed to assess the relationship between extreme heat exposure (exposure) and delinquency (outcome). Covariates included race/ethnicity, sex, and age. Mediators examined were neighborhood SES, puberty, peer deviance, and financial difficulties. Structural equation modeling (SEM) was employed for data analysis. Results: Overall, 11,878 children entered our analysis. The analysis revealed a significant association between extreme heat exposure and higher levels of delinquency among children. Children more exposed to extreme heat were more likely to be Black, reside in lower SES neighborhoods, experience greater financial difficulties, and have more advanced puberty status. The group facing the highest heat exposure was also economically disadvantaged. Conclusions: The findings suggest that children already disadvantaged by socio-economic factors are disproportionately affected by extreme heat, leading to increased delinquency. This highlights the need for targeted interventions to protect these vulnerable populations and address the mediators of extreme heat exposure. Future research should focus on longitudinal studies and evaluate the effectiveness of various mitigation strategies to address these disparities.

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Open Access June 01, 2024

An Assessment of Off-Season Vegetable Farming on Farmers in Savelugu Municipality in the Northern Region

Yakubu Jacob Fuseini

Open Journal of Agricultural Research 2024, 4(1), 1-11. DOI: 10.31586/ojar.2024.933

Abstract The study aimed to assess the impact of off-season vegetable farming on farmers in the Savelugu Municipality in the Northern Region. The study population consisted of all respondents to off-season vegetable farming in the Savelugu Municipality in the five selected communities in the Northern Region. A purposive sampling technique was used for a sample size of fifty (50) off-season farmers in the [...] Read more.

The study aimed to assess the impact of off-season vegetable farming on farmers in the Savelugu Municipality in the Northern Region. The study population consisted of all respondents to off-season vegetable farming in the Savelugu Municipality in the five selected communities in the Northern Region. A purposive sampling technique was used for a sample size of fifty (50) off-season farmers in the selected communities. An interview guide and questionnaire were used to solicit data to conclude the findings. The data derived from the questionnaire were analysed in a step-by-step thematic analysis that included reading the transcriptions several times, coding, generating codes, and reviewing and naming themes. Afterwards, the questionnaire and interview guide responses were transferred into Microsoft Excel under assigned variable names. Descriptive statistics, namely frequency, means, and percentages, were used to analyse the data. Off-season vegetable production technology can be gained by using different agro-climatic regions, maintaining or adjusting planting time, selecting varieties, and creating artificial and controlled environments through tunnels, polytene houses, glass houses, hotbeds, etc. Moreover, Off-Season vegetables helped earn income and ranked highest with an overall mean score of 1. Nearly all the trained farmers said their primary constraint was the high incidence of pests and diseases. It is evident that off-season cultivation is profitable and significantly impacts the farmers' consumption expenditure and food security status. Therefore, providing improved and modern agricultural inputs to off-season farmers is essential for rural agricultural development.

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Review Article

Open Access May 30, 2024

Assessing the Socio-Economic Implications of Free Senior High School (SHS) Policy on Tertiary Institutions in Ghana: A Case Study of the Western Region

Bernice Worlanyo Nyadzi, Dominic Achari, Jacob Tawiah, Michael Kwegyir Koomson, Ronald Osei Mensah

Open Journal of Educational Research 2024, 4(3), 100-111. DOI: 10.31586/ojer.2024.950

Abstract Ghana's Free Senior High School (SHS) policy has been touted as one of the most significant educational reforms in recent years, fueling the nation's achievement of Goal 4 [...] Read more.

Ghana's Free Senior High School (SHS) policy has been touted as one of the most significant educational reforms in recent years, fueling the nation's achievement of Goal 4 of the United Nations Sustainable Development Goals (SDGs). While many studies have been conducted on the policy’s impact on beneficiaries, little is known about its impact on tertiary institutions. The purpose of this study is to evaluate the socioeconomic effects of the Free SHS policy on tertiary institutions in Ghana's Western Region. We also provide suggestions on how to improve the policy's efficacy and lessen any obstacles to its incorporation into higher education. Methodologically, 103 employees of Takoradi Technical University and the University of Mines and Technology were sampled using a purposive sampling technique. According to the report, despite the lack of adequate facilities such as lecture halls, dorms, and residence halls on campus, the Free SHS policy has increased enrollment at the postsecondary level. This has resulted in a high student-to-lecturer ratio, increased utility bills, a high cost of living on campus, and a rise in the opening of businesses on campus. To address some of these socioeconomic impacts, respondents proposed that the government should improve infrastructure in the country's higher institutions, hire more lecturers, boost incentives for lecturers, and foster partnerships with private institutions to support infrastructure development.

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Open Access March 13, 2024

Current Risk in the Supply Chain for the Active Pharmaceutical Ingredients Business

Sourav Adak

Universal Journal of Pharmacy and Pharmacology 2024, 3(1), 1-5. DOI: 10.31586/ujpp.2024.906

Abstract The active pharmaceutical ingredients (API) are very critical substances for generic drugs. Any issue in the global supply chain for sourcing APIs heavily impacts generic drugs demands in the market. It is imperative to keep a close eye on the API supply in order to spot possible priorities for domestic manufacturing as well as bottlenecks in the US pharmaceutical supply chain. Most of the API's [...] Read more.

The active pharmaceutical ingredients (API) are very critical substances for generic drugs. Any issue in the global supply chain for sourcing APIs heavily impacts generic drugs demands in the market. It is imperative to keep a close eye on the API supply in order to spot possible priorities for domestic manufacturing as well as bottlenecks in the US pharmaceutical supply chain. Most of the API's are manufactured in countries like India and China, and any issue in the manufacturing or supply of the API's may critically impact generic drug production globally. The Government and regulatory agencies must take initiatives to mitigate the risk of supply chain interruptions in the API business.

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Open Access November 01, 2023

Serialized Drug Traceability in the Supply Chain Using Distributed Ledger Technology

Shivankar Patra

Universal Journal of Pharmacy and Pharmacology 2023, 2(1), 47-53. DOI: 10.31586/ujpp.2023.815

Abstract Currently, Drug Counterfeiting is the biggest challenge facing the pharmaceutical industry. They are encountering this threat due to high market demand for the drugs and their profit margin. The lack of data transparency and traceability also lured criminals into the counterfeiting of drugs which, is impacting people’s health and put their life in danger. Through the drug supply chain, a [...] Read more.

Currently, Drug Counterfeiting is the biggest challenge facing the pharmaceutical industry. They are encountering this threat due to high market demand for the drugs and their profit margin. The lack of data transparency and traceability also lured criminals into the counterfeiting of drugs which, is impacting people’s health and put their life in danger. Through the drug supply chain, a substantial portion of counterfeit drugs are injected and distributed through the healthcare supply chain network, so the supply chain plays a vital role in drug distribution and impacts patient lives. Through digitalization in the healthcare sector, Distributed Ledger Technology (DLT) provides a platform with ground-breaking results by providing a system for drug traceability with consideration of the critical requirements of transparency, privacy, and authenticity without involving any third party. In DLT, each distribution partner is registered to maintain transparency with the drug information. Real-time transfer of information about the change of ownership with date and time in the form of blocks gives visibility to all the partners in real time about the authenticity of drugs. This article will give information about the benefits of Distributed Ledger Technology to the pharmaceutical industry and the traceability of drugs from end-to-end of the pharmaceutical supply chain.

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Open Access December 22, 2022

Climate Change Impact on Small-Scale Animal Agriculture: Livestock Water & Food Security in Africa

Never Assan

Universal Journal of Food Security 2022, 1(1), 13-39. DOI: 10.31586/ujfs.2022.541

Abstract Water is essential for food security and animal agricultural productivity, but it is becoming more scarce due to climate change. The interaction between climate change and livestock water resources has received little attention from researchers, despite the significance of small-scale animal husbandry for the rural poor in Africa and the size of the changes that are anticipated to have an impact [...] Read more.

Water is essential for food security and animal agricultural productivity, but it is becoming more scarce due to climate change. The interaction between climate change and livestock water resources has received little attention from researchers, despite the significance of small-scale animal husbandry for the rural poor in Africa and the size of the changes that are anticipated to have an impact on smallholder livestock systems. Threats to livestock water are undoubtedly one of the most significant environmental issues that have impacted food security on the continent, given their links to small-scale animal husbandry and the detrimental impacts on productivity. In order to balance the negative effects of climate change scenarios for sustainable animal productivity and contribute to food security through small-scale animal agriculture, the most climate-smart and resilient agricultural water practices and technologies must be used. Changes in rainfall and a decline in the biomass available for grazing and rangelands as a result of water stress brought on by the climate would have the most severe effects. This is due to the rain-fed nature of small-scale livestock farming. The local animal genetic resources are essential for animal productivity and food security in Africa, particularly in areas where livestock water is becoming scarce owing to climate change. Research and development goals on the effects of climate change on livestock water, animal productivity, and food security may need to be reviewed if demands of vulnerable small-scale animal producers are to be successfully addressed in the future decades. It is best to use an interdisciplinary approach to comprehend the relationships between small-scale animal husbandry, food security, and climate change. By navigating the complexities of climate adaptation, small-scale livestock farmers can manage livestock water scarcity by taking adaptation measures that are in line with evolving climate impacts and associated means of implementation based on pertinent and useful knowledge that takes into account a blend of traditional and modern water science. In this paper, an effort is made to close some significant information gaps and shed light on how water-induced stress impacts small-scale animal production, which has an effect on food security.

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Review Article

Open Access November 13, 2022

Effects of Impacted Third Molars Extraction on Periodontal Status of Second Molar and Oral Health-Related Quality of Life

Tie-lou Chen, Pei Wang, Shi-feng Wang, Yan-en Wang, Xin-hai Zhang, Wen-jing Chen, An-xin Yue, Dao Xiang, Xu Feng

Universal Journal of Stomatology 2022, 1(1), 1-11. DOI: 10.31586/ujs.2022.473

Abstract Objective: The study investigated the impacts of third molar (M3) extraction on periodontal status of adjacent second molar (M2) and oral health-related Quality of life (QoL). Methods: 272 cases with M3 were randomly divided into treatment group and control group, each of 136 cases. Questionnaire survey evaluated demographic features of the subjects. Gingival index (GI), [...] Read more.

Objective: The study investigated the impacts of third molar (M3) extraction on periodontal status of adjacent second molar (M2) and oral health-related Quality of life (QoL). Methods: 272 cases with M3 were randomly divided into treatment group and control group, each of 136 cases. Questionnaire survey evaluated demographic features of the subjects. Gingival index (GI), plaque index (PLI) and conscious symptoms of adjacent teeth of the M3 were detected in both groups at baseline (T0), 1 week (T1), 1 month (T2) and 6 months (T3) after treatment. The impacts of QoL were evaluated using OHIP-14 to measure total scores and various items of OHIP-14 at different observation point. Results: The percentage of swelling and toothache in the treatment group was significantly lower than that in the control group at T1, T2 and T3. Significant differences could be seen in GI and PLI between the treatment and control groups at T2 and T3. The total score of OHIP-14 in T2 and T3 was significantly lower than that in T0 and T1 in the treatment group. The 14 items scores and the percentage of positive reaction in the treatment group were significantly lower than those in the control group at T2 and T3. Conclusion: M3 extraction had significant impacts on the periodontal status of the second molar and quality of life. This study would provide an important basis for the prophylactic removal of M3 in clinical work.

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Open Access November 09, 2022

Economic Consequences of Covid-19 in Western Ethiopia: Challenges and Opportunities

Isubalew Daba Ayana, Firdisa Birru Goshu, Desalegn Eticha Deressa, Melkamu Wolde Geleta, Tarekegn Tariku Ebissa, Tesfaye Eresso Gofe, Dugasa Rafisa Olana

Universal Journal of Finance and Economics 2022, 2(1), 52-70. DOI: 10.31586/ujfe.2022.502

Abstract This research is conducted with main aim of assessing the economic consequences of Covid-19 pandemic in Western Ethiopia. Primary data is collected through questionnaire and interview from 320 respondents living in three zones of Western Ethiopia. The study areas (zones) are selected purposively from Oromia region; however, the respondents are sampled by employing random sampling technique. The [...] Read more.

This research is conducted with main aim of assessing the economic consequences of Covid-19 pandemic in Western Ethiopia. Primary data is collected through questionnaire and interview from 320 respondents living in three zones of Western Ethiopia. The study areas (zones) are selected purposively from Oromia region; however, the respondents are sampled by employing random sampling technique. The respondents were stratified as community members, daily laborer, business owners, government sector and NGOs employees. Exploratory research design was adopted to achieve the research objectives. Simple descriptive statistics and ordinary least square regression model are used to analyze and interpret the collected data. The study results disclose that majority of community have good awareness about the pandemic and social interaction is reduced due to social distancing. Majority of respondents realize the negative impact of Covid-19 on their economy; reduction of office services; and reduced access to market; and absence of strong support from the government. The great severity of Covid-19 impacts is failed on daily laborers. The regression result shows that sales, experience in business, education level in years, employment status of the respondent, number of workers in the business and work hours per week are positively and significantly influencing daily income of business owner before and after the pandemic outbreak. It is advised the stakeholders to give frequent follow-up and support particularly for daily laborers and small business holders to reduce the future socio-economic impacts of Covid-19 pandemic.

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Open Access October 24, 2022

Probiotics and Intestinal Microbiome: A Review of Literature

Hadeer Abdel-Aleem Hassan Mohamed Tawfik, Mohamed Nazmy Farris, Rasha Samir, Mohamed Nabil Badawy Al Ashram, Mina Mikhail Nessim, Mohamed Farouk Allam

World Journal of Medical Microbiology 2022, 1(1), 25-29. DOI: 10.31586/wjmm.2022.479

Abstract Probiotics, prebiotics, and synbiotics modify various aspects of local and systemic immune function in multiple experimental models. However, their impact and mechanisms of action are not known across all products or noticed in every population studied, and impacts on in vitro, ex vivo, or other measures of immune function do not necessarily result in an impact on infection and illness in vivo [...] Read more.

Probiotics, prebiotics, and synbiotics modify various aspects of local and systemic immune function in multiple experimental models. However, their impact and mechanisms of action are not known across all products or noticed in every population studied, and impacts on in vitro, ex vivo, or other measures of immune function do not necessarily result in an impact on infection and illness in vivo. Studies have discussed that intestinal microbiota has an essential role in enhancing the immune system against viruses. The regulatory impact of the intestinal microbiota on viral infection is connected with local and systemic immune responses and plays a part in congenital and adaptive immune responses. The microbiota composition critically modulates the production of virus-specific CD4 and CD8 T cells and antibody responses following influenza virus infection. The intestinal microbiota has an important role in the stabilizing of immune homeostasis by augmenting the integrity of the barrier functions of the gut mucosa, which is a crucial aspect of systemic immunity. In conclusion, the intestinal microbiota can influence organismal immunity locally and systemically, proximally, and distally. Studying the possible mechanism by which the intestinal microbiota maintains host immunity can provide a clearer understanding of the occurrence and development of diseases.

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Open Access October 15, 2022

Cyclophosphamide Induces Hepatorenal Toxicity and Attenuation by 5-fluorouracil in Male Albino Rats

Rabia A M Yahya, Ahmed M. Attia, Mona A. Yehia, Azab Elsayed Azab, Karema El.M.Shkal

World Journal of Clinical Medicine Research 2022, 2(1), 8-21. DOI: 10.31586/wjcmr.2022.455

Abstract Background: Cyclophosphamide (CPA) induces acute inflammation of the urinary bladder, renal damage, and liver damage, thereby limiting its therapeutic use. Objectives: The present study aimed to evaluate the hepatorenal toxicity induced by cyclophosphamide and amelioration by 5-fluorouracil in male albino rats. Materials and Methods: Twenty-eight male adult rats were [...] Read more.

Background: Cyclophosphamide (CPA) induces acute inflammation of the urinary bladder, renal damage, and liver damage, thereby limiting its therapeutic use. Objectives: The present study aimed to evaluate the hepatorenal toxicity induced by cyclophosphamide and amelioration by 5-fluorouracil in male albino rats. Materials and Methods: Twenty-eight male adult rats were grouped randomly into four groups (n=5 for each group). Group I (control): Rats were injected with saline intraperitoneally and at a dose of 1.0 ml/kg b.w. for 14 days. Group II cyclophosphamide (CPA): Cyclophosphamide at a dose of 10 mg/kg day by day through i.p. to rats for 14 days. Group III Fluorouracil (5-FU): 5-Fluorouracil at a dose of 10 mg/kg day by day in saline was given through i.p. to rats for 14 days. Group IV (CPA+5-FU): Rats were given CPA followed by 5-FU at a dose of 10 mg/kg per day (day by day) through i.p. to rats for 14 days. At the end of the experimental period, rats were anesthetized using light ether. Blood samples were taken and prepared for biochemical measurements. Results: Serum total protein, albumin, and globulin concentration significantly reduced in animal groups that received cyclophosphamide. 5-FU and CPA combination reduced the changes in total protein, albumin, and globulin compared to CPA treated group. A significant increase in LDH serum concentration was found in CPA, 5-FU, and their combination-treated animals. The mean values of the combination of chemotherapy were above that in CPA followed by 5-FU treatment. Administration of CPA, 5-FU resulted in a significant increase in serum AST, ALT, ALP, and bilirubin compared to the control. Co-treatment 5-FU with CPA significantly attenuated the increase in serum AST, ALT, ALP, and bilirubin when compared to CPA – treated rats. Compared to controls, urea and creatinine levels were increased in CPA-treated rats, while uric acid was reduced in CPA, 5-FU, and their combination. The changes in urea and creatinine produced by the chemotherapy were restored when rats received CPA in combination with 5-FU. Conclusion: It could be concluded that the treatment of mammals with chemotherapy is associated with the production of free radicals that lead to hazardous alterations in biochemical parameters. However, 5-FU and CPA combination could produce a significant amelioration in most cases for these changes, and it may be considered as a potentially useful candidate in the combination chemotherapy with CPA to combat oxidative stress-mediated non-target organ injury even if it was not complete protection. Future work should consider combined chemotherapy regimens, as two or more mechanisms of action of chemotherapeutic drugs could be more powerful than one mechanism. Toxicological studies must be performed before using drugs as a combination before application. Further research is required on the toxicological impacts of drugs and pollutants mixtures.

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Open Access July 05, 2022

Farmers’ Perceptions on the Impacts of Climate Change (CC) on Crops Output

Isaac Verberk Mensah, Samuel Kingsford Twene, Eric Kofi Adjei

Universal Journal of Social Sciences and Humanities 2022, 2(3), 119-132. DOI: 10.31586/ujssh.2022.355

Abstract The study aimed at examining farmers’ perceptions on the impacts of climate change on food crops and the farming practices that contribute to climate change (CC) in Bibiani – Ahwiaso – Bekwai municipality of Western North Region of Ghana. Qualitative and quantitative methods were used for this study. The population of the study consisted of the number of households in six communities (Hwenampori, [...] Read more.

The study aimed at examining farmers’ perceptions on the impacts of climate change on food crops and the farming practices that contribute to climate change (CC) in Bibiani – Ahwiaso – Bekwai municipality of Western North Region of Ghana. Qualitative and quantitative methods were used for this study. The population of the study consisted of the number of households in six communities (Hwenampori, Wenchi, Tanoso, Awaso-Asempanaye, Kunkumso, and Sefwi Bekwai), officials from MoFA, GMA, and heads of households who are food crop farmers from the study area. Simple random and purposive sampling techniques were used to select respondents for the study. 231 respondents were selected and contacted for information to aid them in the study. The main instruments for data collection were the administration of questionnaires to farmers, organization of focus group discussions with key informants, the use of structured interview guides on MoFA directorates and direct observation of some farms. The primary and secondary data were sourced mainly from household heads from the study communities who are in the production of maize, cassava, and plantain. Pearson Chi-Square and Cross-tabulation of the IBM SPSS Version 20 were also used in performing descriptive statistical analysis. The study revealed that the output of maize, cassava, and plantain have all proved to be negatively impacted by changes in rainfall and temperature patterns with a more significant impact observed from maize responses to temperature. The study also indicated that the impact of climate change may affect the crops at any stage of the production process right from the land preparation to the maturity stage of crops but the more profound effect is observed at fruit development and maturation stages. The study indicated that changes in temperature affect crop yield, especially during the fruit/seed development stage. The study revealed that most farmers (about 92.2%) have observed climate change in the study area and indicated events like unpredictable rainfall patterns, excessively high temperatures and strong winds. It is recommended that capacity building and awareness creation should be enhanced by GMA and MoFA through the media to ensure that communication about climate change and food security is meaningful. This means that education on diversification of farming methods has not been enough if there is any at all in the area. Awareness creation, therefore, allows people to make informed and responsible decisions toward sustainable farming practices which will lead to food security and also environmental sustainability.

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Abstract Emotional regulation of children and adolescents is a very important process for their development. Emotional self-regulation encouraged the children and adolescents to control aggressive emotional outbursts. This study purpose is to exam the effect of emotional self-regulation on the life quality of children and adolescents with traumatic experiences. A systematic review was conducted to examine [...] Read more.

Emotional regulation of children and adolescents is a very important process for their development. Emotional self-regulation encouraged the children and adolescents to control aggressive emotional outbursts. This study purpose is to exam the effect of emotional self-regulation on the life quality of children and adolescents with traumatic experiences. A systematic review was conducted to examine research on effect of low emotional self-regulation on the life quality among children and adolescents with traumatic experiences. The initial search generated 1.245 research articles, 170 of which were reviewed for detailed evaluation; ultimately, 11 research articles published in the period 2012-2021 were included. Children and adolescents with traumatic experiences all over the world samples were the most represented in research articles. It used thematic synthesis to combine the research articles of low emotional self-regulation on the life quality among children and adolescents with traumatic experiences and identified key themes to explore in the impact studies. Across 11 articles, regardless of the traumatic type of event, it was found that children and adolescents’ low self-regulation affects their ability to express themselves in a functional and productive way. Negative accumulated emotions, which do not externalize sexually and physically abused children and adolescents with low emotional self-regulation gradually lead to some type of emotional disconnection. In conclusion, sexual, physical abuse and war-refugee situations in childhood are more associated with the onset of post - traumatic stress disorder, emotional disorders and difficulties in self - regulation of emotions.

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