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Open Access January 02, 2025

A review of Opuntia ficus-indica (L.) Mill. ethnobotany in Italy and North Africa

Abstract Opuntia ficus-indica (L.) Mill., commonly known as prickly pear, is a versatile plant widely used for food, medicinal, and cosmetic purposes in various regions of the Mediterranean and North Africa. This study provides a comparative ethnobotanical review of prickly pear uses in Algeria, Morocco, Tunisia, and Italy. In total, 74 articles were selected from ethnobotanical uses in Italy, Algeria, Morocco and Tunisia. In the Maghreb, the plant is used for fruit production and processed products, such as jams, oils, and flours, as well as for traditional medicinal purposes. In Algeria and Morocco, the fruits and cladodes are used to treat digestive disorders, diabetes, and skin diseases. In Tunisia, products derived from O. ficus-indica are also applied in the cosmetic industry and for erosion control. In Italy, particularly in Sicily and Calabria, the prickly pear is a vital resource, used for both food consumption and for medicinal purposes. The cladodes, rich in mucilage, are applied as topical remedies for skin problems, while the fruits are a key ingredient in the preparation of traditional desserts. Furthermore, O. ficus-indica [...] Read more.
Opuntia ficus-indica (L.) Mill., commonly known as prickly pear, is a versatile plant widely used for food, medicinal, and cosmetic purposes in various regions of the Mediterranean and North Africa. This study provides a comparative ethnobotanical review of prickly pear uses in Algeria, Morocco, Tunisia, and Italy. In total, 74 articles were selected from ethnobotanical uses in Italy, Algeria, Morocco and Tunisia. In the Maghreb, the plant is used for fruit production and processed products, such as jams, oils, and flours, as well as for traditional medicinal purposes. In Algeria and Morocco, the fruits and cladodes are used to treat digestive disorders, diabetes, and skin diseases. In Tunisia, products derived from O. ficus-indica are also applied in the cosmetic industry and for erosion control. In Italy, particularly in Sicily and Calabria, the prickly pear is a vital resource, used for both food consumption and for medicinal purposes. The cladodes, rich in mucilage, are applied as topical remedies for skin problems, while the fruits are a key ingredient in the preparation of traditional desserts. Furthermore, O. ficus-indica has historically been used as forage and to produce natural dyes. Results indicate that the versatility of this species, combined with its ability to adapt to extreme climates, makes it a valuable resource for the development of new nutraceutical and cosmetic products. However, further scientific research is necessary to explore the bio-functional potential of this plant and to promote its broader and more sustainable use, especially in arid and semi-arid regions.
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Review Article
Open Access October 13, 2023

A Report of Three Cases with Moderate Psoriasis Treated with New Topical Treatment

Abstract Practice guidelines recommend fixed combinations of calcipotriol, a topical vitamin D analogue, and betamethasone dipropionate, a high potency corticosteroid, as first line topical treatment for mild to moderate plaque psoriasis of the body and scalp. A new foaming lotion for treatment of Psoriasis was developed and patented by the Spanish Ministry of Industry, Trade and Tourism (Invention patent [...] Read more.
Practice guidelines recommend fixed combinations of calcipotriol, a topical vitamin D analogue, and betamethasone dipropionate, a high potency corticosteroid, as first line topical treatment for mild to moderate plaque psoriasis of the body and scalp. A new foaming lotion for treatment of Psoriasis was developed and patented by the Spanish Ministry of Industry, Trade and Tourism (Invention patent reference number 202030824). The foaming lotion is composed of clobetasol, papaverine hydrochloride, spironolactone, milk-peptide-complex and propylene glycol. Three cases with moderate Psoriasis aged 34, 36 and 66 years old were treated with our new foaming lotion for 7-8 days. The three patients reported important improvement in the itching sensations and remission of the scaled lesions. Before and after application of the new foaming lotion, Psoriasis Area Severity Index (PASI) scores improved in the first patient from 24.3 to 1.8, in the second patient from 26.1 to 1.8, and in the third patient from 27 to 1.8. Our results show the short-term effectiveness of the new foaming lotion in treating moderate and extensive Psoriasis. Long follow-up is needed to evaluate the remission period of Psoriasis and possible side effects of the new topical treatment.
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Case Report
Open Access October 03, 2023

Pharmaceutical Drug Serialization: A Comprehensive Review

Abstract A persistent problem in the pharmaceutical industry that has existed for centuries is the prevalence of counterfeit drugs, and the World Health Organization (WHO) estimates that millions of people are affected by this issue each year. In particular, 4 out of 10 drugs in poor or underdeveloped countries may be adulterated, which can lead to severe adverse events. To address this problem, many [...] Read more.
A persistent problem in the pharmaceutical industry that has existed for centuries is the prevalence of counterfeit drugs, and the World Health Organization (WHO) estimates that millions of people are affected by this issue each year. In particular, 4 out of 10 drugs in poor or underdeveloped countries may be adulterated, which can lead to severe adverse events. To address this problem, many countries have implemented regulatory compliance measures such as pharmaceutical drug serialization, which requires the unique identification of every drug package manufactured. This enables tracking and tracing of individual packages throughout the supply chain and helps to prevent counterfeit drugs from entering the market. In this paper, we conduct a systematic review of the serialization process evaluation and its impact on the pharmaceutical industry. We discuss the benefits of pharmaceutical drug serialization, including its ability to improve drug security and reduce adverse events and investigations. We also examine the challenges associated with implementing serialization processes and the regulatory requirements necessary for compliance. Finally, we explore the various tracking and tracing technologies used in serialization processes and their effectiveness in preventing the distribution of counterfeit drugs. Overall, this paper highlights the importance of pharmaceutical drug serialization in ensuring the safety and efficacy of drugs in the healthcare industry, particularly in poor or underdeveloped countries where the problem of adulterated drugs is especially prevalent.
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Review Article
Open Access September 20, 2023

Group-specific Differences in Blood Lead Levels among Occupationally Exposed Workers in Greater Banjul Area, The Gambia

Abstract Occupational lead (Pb) exposure continues to be an important public health problem globally, yet data is lacking on the associated risks and resources available for the prevention of Pb related diseases in low middle income countries (LMICs) like The Gambia. In this study, we used a case-control design to compare blood lead levels (BLLs) between the exposed (auto repair workers) and unexposed [...] Read more.
Occupational lead (Pb) exposure continues to be an important public health problem globally, yet data is lacking on the associated risks and resources available for the prevention of Pb related diseases in low middle income countries (LMICs) like The Gambia. In this study, we used a case-control design to compare blood lead levels (BLLs) between the exposed (auto repair workers) and unexposed (healthcare workers) populations in The Greater Banjul Area. The data was analyzed using Chi square test of independence to determine the characteristic factors associated with BLL. Multivariate logistic regression was used to test the relationship between BLLs for auto repair and healthcare workers and their experiences. The results of this study indicated 82.1% of cases had higher BLLs compared to 52.9% of controls. Also, the proportion of workers with elevated BLLs was higher for certain factors including more than 80% of those with greater than 10 of years job experience, more than 70% of those who worked greater than 5 days a week, worked more than 8 hours per day, did not use personal protective equipment (PPE), were illiterate or had no formal education, and smoked or ate at work. The study results have implications for policies and practice in the auto repair industry and related workplaces in The Gambia and other LMICs with similar settings. Based on the findings of this study, it is essential to initiate discussions to establish national occupational health policies in The Gambia aimed at protecting workers and the general population.
Article
Open Access February 04, 2023

A framework for evaluation of improvement opportunities for environmental impacts on construction works using life cycle assessment and value stream mapping concepts: offsite and onsite building construction

Abstract There have been various concerns about the environmental impact of construction works. This generates a need to take a more proactive approach in evaluating the environmental impacts of construction operations and further explore ways to reduce the environmental impacts. Enormous opportunities exist within the building industry to achieve a reduction in greenhouse gas emissions. The aim of the [...] Read more.
There have been various concerns about the environmental impact of construction works. This generates a need to take a more proactive approach in evaluating the environmental impacts of construction operations and further explore ways to reduce the environmental impacts. Enormous opportunities exist within the building industry to achieve a reduction in greenhouse gas emissions. The aim of the study is to develop a framework for the evaluation of improvement opportunities for environmental impact for onsite and offsite building construction works using life cycle assessment (LCA) and value-stream-mapping concepts. Various tools for LCA exist; however, there is a need for the development of an LCA framework and improvement opportunities that can be localized to various communities to evaluate improvement opportunities for building construction. This study conducts a review of methods to evaluate the LCA of buildings on local construction sites. A procedure for establishing improvement opportunities is also developed. Based on the author’s knowledge and experience, including site visits, using value stream mapping (VSM) techniques, a conceptual framework of the present state map and future state map of residential construction works was developed. The study presents a procedure for the evaluation of improvement opportunities for the environmental impacts of construction operations.
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Article
Open Access December 16, 2022

A Framework for the Application of Optimization Techniques in the Achievement of Global Emission Targets in the Housing Sector

Abstract The building construction industry holds a crucial role in the reduction of greenhouse gas emissions globally. The targets for greenhouse gas emissions may not be achieved without a defined strategic plan to meet up with the set targets from various sectors of the economy. Recognizing the enormous potential that the building industry holds in contributing to global greenhouse gas GHG emission [...] Read more.
The building construction industry holds a crucial role in the reduction of greenhouse gas emissions globally. The targets for greenhouse gas emissions may not be achieved without a defined strategic plan to meet up with the set targets from various sectors of the economy. Recognizing the enormous potential that the building industry holds in contributing to global greenhouse gas GHG emission reduction, this study describes a framework on how optimization techniques can be used as a guide for emission reduction targets for the housing sector using illustrations of the onsite and offsite building construction industry. Given that some of the GHG gases are also sources of air pollution, this study includes a discussion on how the effort to address air pollution can be used to find a consensus towards addressing the concern about GHG emissions. This study presents procedures for simplified methods of estimation of GHG emissions that various municipalities around the globe can use to estimate and report the emissions from the building construction industry. The study presents a unifying strategy for emission management. The study also demonstrates how programming methods can be applied to GHG emissions management. The approach used in this study is transferable to other industries. The study recommends a unifying strategy for the management and control of emissions in the building construction industry. The study also recommends a coordinated effort in sharing best practices for emission control and management from all jurisdictions globally. In the effort to reduce global emission targets, further studies like this and its expansion is recommended for all sectors of the global economy. It is recommended that these studies should be followed by a concrete effort to achieve good implementation of sustainable emission reduction targets globally.
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Article
Open Access January 16, 2026

Evaluating the Effectiveness of Occupational Health and Safety Management Practices in Improving Workplace Safety in Nigerian Construction Sites

Abstract The construction industry remains one of the most hazardous sectors globally, with Nigeria experiencing a high incidence of workplace accidents despite the adoption of Occupational Health and Safety Management (OHSM) frameworks. This study evaluated the effectiveness of OHSM practices in improving workplace safety across construction companies in Nigeria’s coastal cities. A cross-sectional design [...] Read more.
The construction industry remains one of the most hazardous sectors globally, with Nigeria experiencing a high incidence of workplace accidents despite the adoption of Occupational Health and Safety Management (OHSM) frameworks. This study evaluated the effectiveness of OHSM practices in improving workplace safety across construction companies in Nigeria’s coastal cities. A cross-sectional design was employed, combining quantitative surveys of construction workers (n = 1,400) with qualitative interviews of 35 managers and supervisors. Quantitative data were analyzed using SPSS version 28, while thematic analysis was applied to qualitative responses. Findings revealed a generally positive perception of OHSM, with 54.4% of workers rating OHS policy effectiveness as “Good” and 52.0% rating health outcomes as “Good.” However, accident frequency remained a concern, with 46.4% reporting accidents occurred “Occasionally” and 31.9% acknowledging them as “Frequent” or “Very Frequent.” Comparative analysis showed indigenous firms were rated higher in policy effectiveness and health outcomes but also reported slightly higher accident frequencies than international firms. Thematic analysis identified five key monitoring and evaluation strategies including routine inspections, regular training, audits, behavioural reinforcement, and access control, Also, five measures of OHSM effectiveness, including compliance observation, incident tracking, KPIs, employee feedback, and benchmarking. OHSM was found to positively influence project outcomes by reducing compensation costs, enhancing reputation, and improving supervision and quality of work. OHSM practices in Nigeria’s construction sector are perceived as effective in policy and health outcomes, yet accident rates remain a critical challenge. The study underscores the importance of continuous training, stricter enforcement, behavioural reinforcement, and systematic performance evaluation.
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Article
Open Access November 09, 2025

Application of Building Information Modelling (BIM) for Enhancing Safety and Environmental Performance on Construction Sites in Nigeria

Abstract Background: Building Information Modelling (BIM) improves safety planning in construction by enabling visualization and simulation to identify and reduce risks. However, its adoption in Nigeria is limited. This study examines the application of BIM in enhancing safety and environmental performance on construction sites in Nigeria. Methodology: A quantitative cross-sectional survey [...] Read more.
Background: Building Information Modelling (BIM) improves safety planning in construction by enabling visualization and simulation to identify and reduce risks. However, its adoption in Nigeria is limited. This study examines the application of BIM in enhancing safety and environmental performance on construction sites in Nigeria. Methodology: A quantitative cross-sectional survey was conducted using a structured online questionnaire distributed to professionals in Nigeria’s construction industry. A purposive sampling method was employed to target respondents with relevant BIM experience. Data were analysed using SPSS version 28, applying descriptive statistics, chi-square tests, and logistic regression at a 5% significance level. Result: Findings show that BIM was fully adopted by 7.0% of organizations, with only 19.8% of respondents using it to identify safety hazards during planning. While 76.8% reported no notable safety benefit, 19.5% identified improved risk management as the key benefit. Most respondents (80.2%) reported no noticeable environmental benefits. Among those who did, improved energy efficiency was the most cited benefit (16.4%). Respondents with 10 or more years of experience were significantly more likely to report enhanced safety and environmental outcomes (AOR = 4.555; p = 0.003) and adequate BIM utilization (AOR = 3.255; p = 0.023). Those with intermediate BIM experience were also more likely to report high enhancement (AOR = 2.857; p = 0.039) and effective tool use (AOR = 2.881; p = 0.050). Conclusion: This study revealed that BIM has the potential to improve construction outcomes in Nigeria if supported by training, experience, and structured implementation.
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Article
Open Access October 21, 2025

Trends in Smoking and Flavored Tobacco Use in California: Black–White Disparities, 2003–2023

Abstract Background: Tobacco control policies nationwide have contributed to a substantial decline in cigarette and tobacco use, with particularly sharp reductions observed in states such as California that have implemented restrictive bans, strong prevention measures, and high excise taxes. While these policies have led to overall decreases in tobacco use, progress has not necessarily been [...] Read more.
Background: Tobacco control policies nationwide have contributed to a substantial decline in cigarette and tobacco use, with particularly sharp reductions observed in states such as California that have implemented restrictive bans, strong prevention measures, and high excise taxes. While these policies have led to overall decreases in tobacco use, progress has not necessarily been distributed equally across racial groups. Understanding long-term trends by race is critical for addressing equity gaps in tobacco prevention and control. Evidence suggests that some racialized groups may experience slower or delayed declines, raising concerns about equity in public health gains. Methods: We analyzed data from the California Health Interview Survey (CHIS) spanning 2003–2023. Trends in current smoking were examined separately for non-Latino Black and non-Latino White adults. We also assessed current use of flavored tobacco products, given California’s statewide ban enacted in 2021. Changes were evaluated in both absolute terms (percentage point declines) and relative terms (percent reduction from baseline). Results: Smoking prevalence declined from 17.2% in 2003 to 5.2% in 2023 among White adults and from 19.9% to 9.0% among Black adults. This represents a 12.0 percentage point (69.8%) decline for Whites compared with a 10.9 percentage point (54.8%) decline for Blacks. For flavored tobacco use, prevalence decreased from 8.0% to 4.7% among White adults but only from 11.9% to 10.8% among Black adults. This corresponds to a 3.3 percentage point (41.3%) decline for Whites compared with a 1.1 percentage point (9.2%) decline for Blacks. Conclusions: Although both Black and White adults in California experienced reductions in smoking over the past two decades, White adults showed larger declines in both absolute and relative terms. Disparities were even more pronounced for flavored tobacco use, where declines were minimal among Black adults despite the statewide ban. These findings suggest that Black populations in California may have been left behind by tobacco control progress, especially regarding flavored products. Given the history of targeted marketing by the tobacco industry, the role of flavors in increasing dependence, and reduced access to cessation resources in Black communities, targeted policies and culturally tailored interventions are needed to ensure equitable reductions in tobacco use. Greater attention to flavored tobacco in Black communities may help narrow these disparities and advance California’s tobacco endgame goals.
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Article
Open Access September 14, 2025

Lifecycle Management as a Roadmap to the Tobacco Endgame

Abstract Background: Tobacco endgame, defined as elimination of commercial tobacco sales The U.S. tobacco control landscape is a complex, adaptive system shaped by diverse stakeholders, evolving products and regulations, shifting social norms, and the strategic countermeasures of a powerful industry. Managing such complexity requires more than isolated interventions—it demands a coordinated, [...] Read more.
Background: Tobacco endgame, defined as elimination of commercial tobacco sales The U.S. tobacco control landscape is a complex, adaptive system shaped by diverse stakeholders, evolving products and regulations, shifting social norms, and the strategic countermeasures of a powerful industry. Managing such complexity requires more than isolated interventions—it demands a coordinated, enterprise-wide approach that accounts for dynamic interactions, feedback loops, and emergent risks. Objective: Drawing on complex systems thinking, Zachman enterprise architecture model, and public health best practices, we conceptualize tobacco control as an evolving enterprise progressing through six interconnected phases: (1) Conception & Initiation, (2) Policy & System Design, (3) Implementation & Operation, (4) Evaluation & Adaptation, (5) Consolidation & Endgame Transition, and (6) Sustainment or Sunset. Each phase incorporates governance structures, performance benchmarks, and transition criteria designed to manage interdependence and reduce systemic vulnerabilities. Results: The lifecycle framing emphasizes how tobacco control in the U.S. can evolve as a complex, adaptive enterprise—integrating public health objectives with legal, operational, and cultural change processes. This model supports strategic sequencing, cross-sector alignment, and risk mitigation against emergent industry tactics, enabling a resilient and measurable pathway to the endgame. Conclusions: Seeing tobacco control as a complex enterprise that operates under a lifecycle model may offer a roadmap for achieving and sustaining the tobacco endgame. Using this approach may enhance policy coherence, resource efficiency, and adaptability, ensuring tobacco endgame is achieved.
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Article
Open Access April 10, 2025

Advancements in Pharmaceutical IT: Transforming the Industry with ERP Systems

Abstract The pharmaceutical industry is undergoing a profound transformation driven by advancements in Information Technology (IT), with Enterprise Resource Planning (ERP) systems playing a pivotal role in reshaping operations. These systems offer integrated solutions that streamline key business processes, such as production, inventory management, supply chain optimization, regulatory compliance, and data [...] Read more.
The pharmaceutical industry is undergoing a profound transformation driven by advancements in Information Technology (IT), with Enterprise Resource Planning (ERP) systems playing a pivotal role in reshaping operations. These systems offer integrated solutions that streamline key business processes, such as production, inventory management, supply chain optimization, regulatory compliance, and data integration, contributing significantly to operational efficiency and organizational agility. This paper explores the evolution and impact of ERP systems within the pharmaceutical sector, highlighting their contributions to overcoming the industry’s inherent challenges, including complex regulatory requirements, the need for accurate and real-time data, and the demand for supply chain resilience. The integration of cloud-based ERP solutions, the incorporation of emerging technologies like Artificial Intelligence (AI), Machine Learning (ML), and the Internet of Things (IoT), and enhanced data analytics capabilities have revolutionized pharmaceutical IT. These advancements not only reduce operational costs, improve forecasting accuracy, and enhance collaboration but also ensure compliance with stringent global regulations, such as Good Manufacturing Practices (GMP) and FDA guidelines. Moreover, ERP systems have been instrumental in managing the pharmaceutical supply chain, ensuring product traceability, and improving inventory control and order fulfillment processes. This manuscript examines how ERP systems enable pharmaceutical companies to maintain high standards of product quality, improve decision-making, and ensure the safety and efficacy of drugs through robust tracking and auditing mechanisms. A case study of a pharmaceutical company that implemented an ERP system demonstrates the tangible benefits, including increased operational efficiency, improved compliance rates, and enhanced customer satisfaction. However, despite the clear advantages, challenges such as customization complexities, data integration issues, and resistance to change remain. As the pharmaceutical industry continues to evolve, ERP systems will remain a cornerstone of digital transformation, facilitating smarter decision-making, better resource management, and enhanced collaboration across global operations. This paper also identifies future trends, including the potential of AI and blockchain technologies in further strengthening ERP systems and transforming the pharmaceutical landscape.
Review Article
Open Access March 11, 2025

Why High Income Fails to Reduce E-Cigarette Use: The Knowledge-Attitude Paradox in the SMOKES Study

Abstract Background: Electronic cigarette (e-cigarette) use and vaping tobacco have increased rapidly worldwide, raising concerns about their health effects, social acceptability, and regulatory challenges. In many countries, e-cigarettes are more commonly used by individuals from higher socioeconomic status (SES) backgrounds, who, in theory, should have greater knowledge about e-cigarettes and [...] Read more.
Background: Electronic cigarette (e-cigarette) use and vaping tobacco have increased rapidly worldwide, raising concerns about their health effects, social acceptability, and regulatory challenges. In many countries, e-cigarettes are more commonly used by individuals from higher socioeconomic status (SES) backgrounds, who, in theory, should have greater knowledge about e-cigarettes and their associated risks. However, it remains unclear why a group with more knowledge about e-cigarette risks would also hold more positive attitudes toward vaping and exhibit higher usage rates — a phenomenon that may represent a knowledge-behavior paradox. Understanding this paradox, along with the complex relationships between e-cigarette knowledge, attitudes, and behaviors, is critical for informing effective public health interventions, campaigns, social media messaging, and regulatory policies. Objectives: This study aimed to evaluate the complex relationship between SES, e-cigarette knowledge, pro-vaping attitudes, and e-cigarette use. Methods: The SMOKES Study (Study of Measurement of Knowledge and Examination of Support for Tobacco Control Policies) used a multi-center, cross-sectional design, collecting data from 2,403 college and university students across 15 provinces in Iran (covering nearly half of the country's provinces). The survey measured family income, age, sex, ethnicity, e-cigarette use, knowledge, and attitudes. Structural Equation Modeling (SEM) was employed to examine the interrelations between SES, knowledge, attitudes, and behavior, while adjusting for age, sex, and ethnic minority status. Results: SEM analysis confirmed the hypothesized paradox. Although greater knowledge about e-cigarettes was linked to less favorable attitudes toward vaping and lower use, pro-vaping attitudes emerged as the strongest predictor of vaping behavior, while knowledge played a weaker protective role. Notably, individuals with higher SES simultaneously showed higher knowledge and, paradoxically, more pro-e-cigarette attitudes and greater usage. Female students and ethnic minority students reported higher correct knowledge and lower pro-vaping attitudes and use. Although age and higher family income were associated with more favorable attitudes, they did not directly predict vaping behavior. These results suggest that for higher SES individuals, poor knowledge is not the main driver of e-cigarette use; rather, their pro-e-cigarette attitudes, which seem to outweigh the influence of knowledge, play a key role. Conclusions: Although individuals from higher SES backgrounds report greater correct knowledge about e-cigarettes, this knowledge does not necessarily translate into reduced positive attitudes or lower usage. This study highlights the complexity of these paradoxical effects and suggests that public health strategies need to go beyond simple education and knowledge-based interventions. Targeted approaches should address industry messaging, challenge misconceptions, and strengthen regulatory efforts to reduce e-cigarette use among young adults, including those from higher SES backgrounds.
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Original Article
Open Access February 26, 2025

Innovations and Challenges in Pharmaceutical Supply Chain, Serialization and Regulatory Landscape

Abstract The pharmaceutical supply chain has become increasingly complex and vulnerable to various risks, including counterfeit drugs, diversion, and fraud. As these challenges threaten patient safety and the integrity of global healthcare systems, serialization has emerged as a pivotal innovation in pharmaceutical logistics and regulatory compliance. Serialization involves assigning unique identifiers to [...] Read more.
The pharmaceutical supply chain has become increasingly complex and vulnerable to various risks, including counterfeit drugs, diversion, and fraud. As these challenges threaten patient safety and the integrity of global healthcare systems, serialization has emerged as a pivotal innovation in pharmaceutical logistics and regulatory compliance. Serialization involves assigning unique identifiers to individual drug packages, enabling precise tracking and authentication at every stage of the supply chain. This process provides unprecedented transparency, enhances product security, and facilitates real-time monitoring of pharmaceutical products as they move from manufacturers to end consumers. Despite its potential to revolutionize pharmaceutical traceability, the integration of serialization technologies faces numerous obstacles. These include high implementation costs, regulatory inconsistencies across regions, and the technological challenges of managing vast amounts of data. Moreover, the complex, multi-tiered nature of the global supply chain introduces additional risks related to data integrity, cybersecurity, and interoperability between systems. As pharmaceutical companies seek to navigate these challenges, innovations in serialization technology—such as blockchain, artificial intelligence (AI), the Internet of Things (IoT), and radio frequency identification (RFID)—are providing promising solutions to enhance efficiency, reduce fraud, and increase visibility. This manuscript explores both the innovative advancements and the key challenges associated with the integration of serialization in the pharmaceutical supply chain. It delves into the evolving regulatory landscape, highlighting the need for global harmonization of serialization standards, and examines the impact of serialization on securing pharmaceutical distribution networks. Additionally, the paper emphasizes the importance of collaboration among manufacturers, technology providers, and regulatory bodies in overcoming implementation barriers and realizing the full potential of serialization. As the pharmaceutical industry moves towards a more interconnected and data-driven future, serialization promises to play a central role in shaping the next generation of drug safety and supply chain management. By addressing the hurdles to adoption and leveraging emerging technologies, the pharmaceutical sector can create a more secure, transparent, and efficient supply chain that better serves public health and fosters greater trust among consumers and healthcare professionals alike.
Review Article
Open Access January 09, 2025

Advances in the Synthesis and Optimization of Pharmaceutical APIs: Trends and Techniques

Abstract The synthesis and optimization of Active Pharmaceutical Ingredients (APIs) is fundamental to pharmaceutical drug development, directly influencing drug efficacy, safety, and cost-effectiveness. Over recent years, significant advancements in synthetic methodologies and manufacturing technologies have transformed API production. This manuscript provides an overview of the latest innovations in API [...] Read more.
The synthesis and optimization of Active Pharmaceutical Ingredients (APIs) is fundamental to pharmaceutical drug development, directly influencing drug efficacy, safety, and cost-effectiveness. Over recent years, significant advancements in synthetic methodologies and manufacturing technologies have transformed API production. This manuscript provides an overview of the latest innovations in API synthesis, focusing on key techniques such as green chemistry, continuous flow chemistry, biocatalysis, and automation. Green chemistry principles, including solvent substitution and catalytic reactions, have enhanced sustainability by reducing waste and energy consumption. Continuous flow chemistry offers improved reaction control, scalability, and safety, while biocatalysis provides an eco-friendly alternative for synthesizing complex and chiral APIs. Additionally, the integration of automation and advanced process control using machine learning and real-time monitoring has optimized production efficiency and consistency. The manuscript also discusses the challenges associated with regulatory compliance and quality assurance, highlighting the role of advanced analytical techniques such as HPLC, NMR, and mass spectrometry in ensuring API purity. Looking ahead, personalized medicine and smart manufacturing technologies, including blockchain for traceability, are expected to drive further innovation in API production. This review concludes by emphasizing the need for continued advancements in sustainability, efficiency, and scalability to meet the evolving demands of the pharmaceutical industry, ultimately enabling the development of safer, more effective, and environmentally responsible medicines.
Review Article
Open Access November 27, 2024

Bead Jewellery Industry in Ghana: Problems and Solutions

Abstract Bead jewellery is common in all Ghanaian communities. Bead jewellers are well-known for their important bead jewellery production and have advanced to the Master craft level. The industry can be utilized if the industry's difficulties are discovered and remedied. The study area for the research includes Ghana's Eastern, Ashanti, and Greater Accra Regions. The study's population included bead [...] Read more.
Bead jewellery is common in all Ghanaian communities. Bead jewellers are well-known for their important bead jewellery production and have advanced to the Master craft level. The industry can be utilized if the industry's difficulties are discovered and remedied. The study area for the research includes Ghana's Eastern, Ashanti, and Greater Accra Regions. The study's population included bead jewellers, bead jewellery firms, bead dealers, bead aficionados, clients, and bead makers. With a sample size of 30, data was gathered mostly through direct observations, interviews, and document reviews. The study went over the procedure for securing land for a bead jewellery workshop. According to a survey conducted by the Ghanaian Chamber of Commerce and Industry (GCCII), Ghanaian bead jewellers should use qualified designers. Cost pooling in legal services, accounting, and consulting is likely to save money.
Case Study
Open Access November 07, 2024

Optimizing Pharmaceutical Supply Chain: Key Challenges and Strategic Solutions

Abstract Pharmaceutical supply chains are critical to ensuring the availability of safe and effective medications, yet they face numerous challenges that can jeopardize public health. This article provides a comprehensive analysis of the key issues impacting pharmaceutical supply chains, including regulatory compliance, demand forecasting, supply chain visibility, quality assurance, and geopolitical risks. [...] Read more.
Pharmaceutical supply chains are critical to ensuring the availability of safe and effective medications, yet they face numerous challenges that can jeopardize public health. This article provides a comprehensive analysis of the key issues impacting pharmaceutical supply chains, including regulatory compliance, demand forecasting, supply chain visibility, quality assurance, and geopolitical risks. Regulatory compliance remains a significant concern due to the stringent guidelines imposed by authorities such as the FDA and EMA, which can lead to increased operational costs and time delays. Additionally, traditional demand forecasting methods often fail to accurately predict fluctuations in drug demand, resulting in stockouts or excess inventory. Limited supply chain visibility further complicates these challenges, hindering timely decision-making and operational efficiency. Quality assurance is paramount, as maintaining the integrity of pharmaceutical products throughout the supply chain is crucial to preventing costly recalls and ensuring patient safety. Moreover, the globalization of supply chains introduces vulnerabilities to geopolitical risks, trade disputes, and natural disasters. In response to these issues, this article outlines strategic recommendations for optimizing pharmaceutical supply chains. These include leveraging advanced analytics and IoT technologies to enhance demand forecasting and visibility, strengthening compliance through automated systems and training, fostering collaboration among stakeholders, implementing robust risk management frameworks, and investing in quality management systems. By adopting these strategies, pharmaceutical companies can enhance the efficiency and resilience of their supply chains, ultimately ensuring the continuous availability of essential medications for patients worldwide. This analysis serves as a critical resource for industry professionals seeking to navigate the complexities of pharmaceutical supply chains in an increasingly dynamic global environment.
Review Article
Open Access November 01, 2024

Impacts of Drug Shortages in the Pharmaceutical Supply Chain

Abstract Drug shortages represent a significant and growing challenge within the pharmaceutical supply chain, with profound implications for patient care, public health, and healthcare costs. This manuscript provides a comprehensive examination of the causes and impacts of drug shortages, highlighting the multifaceted nature of this issue. Key factors contributing to shortages include manufacturing [...] Read more.
Drug shortages represent a significant and growing challenge within the pharmaceutical supply chain, with profound implications for patient care, public health, and healthcare costs. This manuscript provides a comprehensive examination of the causes and impacts of drug shortages, highlighting the multifaceted nature of this issue. Key factors contributing to shortages include manufacturing complications, limited availability of active pharmaceutical ingredients (APIs), market dynamics that discourage the production of less profitable medications, and regulatory challenges that slow down the approval process for new manufacturing capacities. The consequences of these shortages are far-reaching. Patients often face treatment delays, which can lead to adverse health outcomes, increased hospitalization rates, and even mortality. Healthcare providers experience heightened operational costs as they seek alternative therapies and manage complications resulting from inadequate treatment. Furthermore, the frequent occurrence of drug shortages erodes public trust in both the healthcare system and the pharmaceutical industry, leading to decreased patient adherence to prescribed therapies. To mitigate the impacts of drug shortages, this manuscript proposes several strategic solutions, including enhanced communication among stakeholders, diversification of supply sources, increased regulatory flexibility, and collaborative approaches between public and private sectors. Additionally, raising awareness among healthcare providers and patients regarding the causes and potential alternatives can empower stakeholders to navigate shortages effectively. Ultimately, addressing drug shortages necessitates a proactive and coordinated effort from all participants in the pharmaceutical supply chain. By implementing these strategies, stakeholders can enhance the resilience of the supply chain, ensuring that essential medications remain accessible and that patient care is not compromised. The findings of this manuscript underscore the urgent need for ongoing vigilance and collaborative action to tackle the challenges posed by drug shortages, safeguarding public health and improving healthcare outcomes globally.
Review Article
Open Access July 21, 2024

Securing Pharmaceutical Supply chain to Combat Active Pharmaceutical Ingredient Counterfeiting

Abstract Pharmaceutical Product serialization aims to assign distinct serial numbers to items within a pharmaceutical supply chain. However, this process faces several security challenges like Theft of valid serial numbers may occur, enabling the labelling of counterfeit products. Therefore, it's essential to ensure the uniqueness of serial numbers can be verified at any point in the product's lifecycle [...] Read more.
Pharmaceutical Product serialization aims to assign distinct serial numbers to items within a pharmaceutical supply chain. However, this process faces several security challenges like Theft of valid serial numbers may occur, enabling the labelling of counterfeit products. Therefore, it's essential to ensure the uniqueness of serial numbers can be verified at any point in the product's lifecycle within the supply chain. Intimidatory nodes along the distribution network could corrupt planned changes of custody for products. Ensuring verifiability of compliance with these changes is crucial. Manufacturers and consumers need assurance that perishable goods with expired shelf lives are appropriately discarded. In this paper, we review a product serialization method leveraging blockchain technology to address these security concerns within a multi-party perishable goods supply chain. Blockchains offer potential solutions by providing a secure platform for data sharing in multi-party environments, enhancing security and transparency. Within Blockchain technology, each distribution partner is registered to uphold transparency regarding drug information. The system facilitates real-time transfer of ownership changes, recording them as blocks with date and time stamps. This ensures visibility to all partners in real time, maintaining the authenticity of drugs. This article aims to outline how Blockchain technology benefits the pharmaceutical industry by enhancing traceability and trackability of drugs throughout the entire pharmaceutical supply chain.
Review Article
Open Access May 12, 2024

Socio-Demographic Factors Influencing Work-Family Conflict Among Hotel Managers

Abstract This study examines the influence of socio-demographic factors on work-family conflict among management staff in star-rated hotels in the Accra Metropolis. The research aims to explore how variables such as gender, age, marital status, and educational background impact the experiences of work-family conflict among hotel managers. A quantitative research design was employed, and data were collected [...] Read more.
This study examines the influence of socio-demographic factors on work-family conflict among management staff in star-rated hotels in the Accra Metropolis. The research aims to explore how variables such as gender, age, marital status, and educational background impact the experiences of work-family conflict among hotel managers. A quantitative research design was employed, and data were collected through structured questionnaires distributed to a purposive sample of hotel managers. The findings reveal significant associations between socio-demographic characteristics and work-family conflict, highlighting the complexities of balancing work responsibilities with family obligations in the hospitality industry. The implications of the study underscore the importance of tailored interventions to support the well-being of hotel managers, while the recommendations emphasise the implementation of work-life balance programs, support for family obligations, promotion of diversity and inclusion, and continuous training and development. It is recommended that hotel organisations create a supportive work environment that enhances the job satisfaction and productivity of their management staff. This study contributes valuable insights to the existing literature on work-family conflict in the hospitality sector and provides a foundation for future research endeavours in this area.
Article
Open Access April 16, 2024

Revolutionizing Automotive Supply Chain: Enhancing Inventory Management with AI and Machine Learning

Abstract Consumer behavior is evolving, demanding a wide range of products with fast shipping and reliable service. The automotive aftermarket industry, worth billions, requires efficient distribution systems to stay competitive. Manufacturers strive to balance growth with product and service excellence. Distributors and retailers face the challenge of maintaining competitive pricing while keeping [...] Read more.
Consumer behavior is evolving, demanding a wide range of products with fast shipping and reliable service. The automotive aftermarket industry, worth billions, requires efficient distribution systems to stay competitive. Manufacturers strive to balance growth with product and service excellence. Distributors and retailers face the challenge of maintaining competitive pricing while keeping inventory levels low. An adequate supply chain and accurate product data are crucial for product availability and reducing stock issues. This ultimately increases profits and customer satisfaction.
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Article
Open Access November 15, 2023

Predictive Failure Analytics in Critical Automotive Applications: Enhancing Reliability and Safety through Advanced AI Techniques

Abstract Failure prediction can be achieved through prognostics, which provides timely warnings before failure. Failure prediction is crucial in an effective prognostic system, allowing preventive maintenance actions to avoid downtime. The prognostics problem involves estimating the remaining useful life (RUL) of a system or component at any given time. The RUL is defined as the time from the current time [...] Read more.
Failure prediction can be achieved through prognostics, which provides timely warnings before failure. Failure prediction is crucial in an effective prognostic system, allowing preventive maintenance actions to avoid downtime. The prognostics problem involves estimating the remaining useful life (RUL) of a system or component at any given time. The RUL is defined as the time from the current time to the time of failure. The goal is to make accurate predictions close to the failure time to provide early warnings. J S Grewal and J. Grewal provide a comprehensive definition of RUL in their paper "The Kalman Filter approach to RUL estimation." A process is a quadruple (XU f P), where X is the state space, U is the control space, P is the set of possible paths, and f represents the transition between states. The process involves applying control values to change the system's state over time.
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Article
Open Access December 06, 2023

Success Factors of Adopting Cloud Enterprise Resource Planning

Abstract The technologies for cloud ERP (Enterprise Resource Planning) have revolutionized the field of information technologies. Any kind of business can benefit from their flexibility, affordability, scalability, adaptation, availability, and customizable data. An advancement of classic ERP, cloud enterprise resource planning (C-ERP) provides the benefits of cloud computing (CC), including resource [...] Read more.
The technologies for cloud ERP (Enterprise Resource Planning) have revolutionized the field of information technologies. Any kind of business can benefit from their flexibility, affordability, scalability, adaptation, availability, and customizable data. An advancement of classic ERP, cloud enterprise resource planning (C-ERP) provides the benefits of cloud computing (CC), including resource elasticity and ease of use. The rise of cloud computing affects on-premise ERP systems in terms of architecture and cost. Cloud-based ERP systems make the claim to be appropriate for digital corporate settings. System quality, security, vendor lock-in, and data accessibility are recognized as the technological issues. Industry 4.0 refers to the re-engineering and revitalization of modern factories through the integration of cloud-based operations, industrial internet connectivity, additive manufacturing, and cybersecurity platforms. One of the four main pillars of Industry 4.0, cloud-based Enterprise Resource Planning (Cloud ERP), is a component of cloud operations that aids in achieving greater standards of sustainable performance.
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Review Article
Open Access November 01, 2023

Serialized Drug Traceability in the Supply Chain Using Distributed Ledger Technology

Abstract Currently, Drug Counterfeiting is the biggest challenge facing the pharmaceutical industry. They are encountering this threat due to high market demand for the drugs and their profit margin. The lack of data transparency and traceability also lured criminals into the counterfeiting of drugs which, is impacting people’s health and put their life in danger. Through the drug supply chain, a [...] Read more.
Currently, Drug Counterfeiting is the biggest challenge facing the pharmaceutical industry. They are encountering this threat due to high market demand for the drugs and their profit margin. The lack of data transparency and traceability also lured criminals into the counterfeiting of drugs which, is impacting people’s health and put their life in danger. Through the drug supply chain, a substantial portion of counterfeit drugs are injected and distributed through the healthcare supply chain network, so the supply chain plays a vital role in drug distribution and impacts patient lives. Through digitalization in the healthcare sector, Distributed Ledger Technology (DLT) provides a platform with ground-breaking results by providing a system for drug traceability with consideration of the critical requirements of transparency, privacy, and authenticity without involving any third party. In DLT, each distribution partner is registered to maintain transparency with the drug information. Real-time transfer of information about the change of ownership with date and time in the form of blocks gives visibility to all the partners in real time about the authenticity of drugs. This article will give information about the benefits of Distributed Ledger Technology to the pharmaceutical industry and the traceability of drugs from end-to-end of the pharmaceutical supply chain.
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Review Article
Open Access November 01, 2023

Role of Enterprise Applications for Pharmaceutical Drug Traceability

Abstract The role of enterprise applications in pharmaceutical industries is driving the digital transformation of various critical processes, and one process benefiting from this innovation is pharmaceutical drug traceability. This industry grapples with challenges like a lack of transparency, difficulties in tracking products, a deficit of trust, and issues related to shipping expired products. To [...] Read more.
The role of enterprise applications in pharmaceutical industries is driving the digital transformation of various critical processes, and one process benefiting from this innovation is pharmaceutical drug traceability. This industry grapples with challenges like a lack of transparency, difficulties in tracking products, a deficit of trust, and issues related to shipping expired products. To address these concerns, blockchain technology as an enterprise application has been harnessed as a solution. Notably, counterfeit drug prevention emerged as the most prevalent category, aligning with the pharmaceutical industry's primary objective. Blockchain technology is an emerging innovation that is finding enterprise applications in various industries, including healthcare. In the healthcare sector, Blockchain networks are being utilized to securely store and exchange patient data across hospitals, diagnostic laboratories, pharmacies, and medical practitioners. These enterprise applications can effectively identify and mitigate critical errors, including potentially hazardous ones within the realm of healthcare. Consequently, this enterprise technology holds the promise of enhancing the efficiency, security, and transparency of medical data sharing within the healthcare system. Moreover, it offers valuable tools for medical institutions to gain insights and improve the analysis of medical records. It visually represents the diverse capabilities, enablers, and the unified workflow process of Blockchain technology in supporting healthcare on a global scale. Additionally, the paper presents a thorough discussion of fourteen significant applications of Blockchain in healthcare, underscoring its pivotal role in addressing issues like deception in clinical trials.
Review Article
Open Access August 16, 2023

Pharmaceutical Drug Traceability by Blockchain and IoT in Enterprise Systems

Abstract Pharmaceutical drug traceability is a regulatory compliance adopted by most nations in the world. A comprehensive analysis was carried out to explain the benefits of adopting enterprise system for pharmaceutical drug traceability. Counterfeit drugs are medicines that are fake and have been produced using incorrect potency, or incorrect ingredients used to manufacture these drugs. Solving the drug [...] Read more.
Pharmaceutical drug traceability is a regulatory compliance adopted by most nations in the world. A comprehensive analysis was carried out to explain the benefits of adopting enterprise system for pharmaceutical drug traceability. Counterfeit drugs are medicines that are fake and have been produced using incorrect potency, or incorrect ingredients used to manufacture these drugs. Solving the drug counterfeiting problems by identifying the most effective and innovative technologies for protecting people's health is of essence these days for the world. Drug serialization is essential concept for drug traceability in the pharmaceutical supply chain. Blockchain is the latest stringent technology that makes drug distribution more secure in the supply chain. The blockchain-based drug traceability is a distributed shared data platform that shares information that is irreversible, reliable, responsible, and transparent in the PSC. Blockchain uses two powerful module, Hyperledger Fabric and Besu to satisfy important criteria for medication traceability, such as privacy, trust, transparency, security, authorization and authentication, and scalability. Researchers in Health informatics can use blockchain designs as a useful road map to develop and implement end-to-end pharmaceutical drug traceability in the supply chain to prevent drug counterfeiting. Industrial IoT is also a key component for the pharmaceutical industry. IoT systems in pharmaceutical drug traceability can be beneficial as they are based on automation and computational methodologies.
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Review Article
Open Access July 29, 2023

Critical Success Factors of Adopting an Enterprise System for Pharmaceutical Drug Traceability

Abstract For conducting advanced analytics initiatives to acquire in-depth data into usage habits, regional access, sales, and promotional success, etc., unique identification of packaged pharmaceuticals will be a fantastic enabler. The main objective of this study is to prevent and reduce the production of erroneous and counterfeit drugs using the enterprise system, which has become a serious threat [...] Read more.
For conducting advanced analytics initiatives to acquire in-depth data into usage habits, regional access, sales, and promotional success, etc., unique identification of packaged pharmaceuticals will be a fantastic enabler. The main objective of this study is to prevent and reduce the production of erroneous and counterfeit drugs using the enterprise system, which has become a serious threat because it damages the reputation of legitimate drug manufacturers by trying to produce and market placebo medications that are identical to the real thing. Due to federal government procedures and priorities that frequently change over time, the majority of implementation takes time. To achieve compliance with numerous federal regulatory authorities, including drug traceability for patient safety, the pharmaceutical industry must implement a systematic procedure in an ERP environment. The goals would be to guarantee medical drug traceability and provide real-time warnings to supply chain stakeholders and regulatory bodies to maximize the benefit of integrating a drug traceability system into an ERP environment. Additionally, manufacturers are compelled to maintain product costs on the higher side due to a heavy burden of unchecked manufacturing cost spikes. As a result, innovative marketing schemes must be introduced in order to increase the reach to consumers by putting into practice successful strategies.
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Review Article
Open Access February 03, 2023

Structural Vector Autoregressive Analysis of Crude Oil Price Shocks on Ghana’s Economy

Abstract The paper analyses the extent to which crude oil price shocks impact GDP growth, exchange rate, interest rate and inflation of an emerging oil exporting economy, Ghana. The Structural Vector Autoregressive model is used to analyse the quarterly data from 2009q1 – 2020q4. The results showed that exchange rate and GDP growth respond positively but temporal to the impulse of crude oil price. In [...] Read more.
The paper analyses the extent to which crude oil price shocks impact GDP growth, exchange rate, interest rate and inflation of an emerging oil exporting economy, Ghana. The Structural Vector Autoregressive model is used to analyse the quarterly data from 2009q1 – 2020q4. The results showed that exchange rate and GDP growth respond positively but temporal to the impulse of crude oil price. In contrast, inflation and interest rate respond negatively to crude oil price shock. Specifically, the exchange rate appreciates in the initial quarter and begins to depreciate, whereas GDP growth experiences an increase in the first two quarters and also reduces afterwards. Crude oil price shocks to the Ghanaian economy follow the conventional behaviour of the impact of crude oil on macroeconomic indicators. The positive impact of the price shock on GDP growth and exchange rate is not much reflecting the fact that Ghana is an emerging oil-producing country with low production and export level. Ghana’s prospects in the oil and gas sector should not just be a mere hoax. Policies should be directed toward petroleum exploration and production efforts since the energy transition endanger benefits for future exploitation. Policies should be implemented to attract competitive players locally and internationally in the oil industry. The shock of crude oil prices is beginning to show evidence based on this study. Therefore government must consider recognising the importance of other economic sectors in order not be become heavily dependent on oil.
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Article
Open Access December 23, 2022

Climate Change's Impact on Agriculture and Food Security: An Opportunity to Showcase African Animal Genetic Resources

Abstract One of the current issues facing humanity is ensuring sustained global food security in the face of devastating effects of climate change; this challenge is particularly pressing on the African continent. Here, I present an opinion piece identifying local animal genetic resources as "African leverage point" that provide the highest chances to cushion rural fork to climate change, enhance [...] Read more.
One of the current issues facing humanity is ensuring sustained global food security in the face of devastating effects of climate change; this challenge is particularly pressing on the African continent. Here, I present an opinion piece identifying local animal genetic resources as "African leverage point" that provide the highest chances to cushion rural fork to climate change, enhance environmental sustainability and food security in Africa. When it comes to boosting food production, coping with climate change, or bolstering the delivery of a wide range of ecosystem services, I believe that African animal genetic resources are essential alternatives for the sustainable growth of the livestock industry and its contribution to food security. Africa needs to address the support and development of indigenous animal genetic resources in order to meet the basic food needs of more than 1 billion people, address numerous environmental issues with continental implications, and focus on more effective and resilient food systems with the greatest impact on food security. The indigenous animal resources diversity and support actions to this unique group could provide a boost in protein that is lacking to constitute healthy diets in Africa. The priorities of nonprofit organizations, foundations, governments, citizens' groups, and companies can be influenced by this leverage point in the African food system. Due to continuous food insecurity, which appears to be becoming worse with climate change and makes it even harder to accomplish the SDGs on the continent, Africa has paid a hefty price for being misled about the worth of its own animal genetic resources. To the contrary, it is highly improbable that a strategy to improve food security and rural livelihoods that undermines the utilization of indigenous animal genetic resources will be viable in long-term. If Africa makes an effort, is committed, and fully commits resources to putting indigenous animal genetic resources at the forefront of combating food insecurity and accelerating the achievement of SDGs, it can achieve more under the adverse prevailing climate change induce environmental conditions. Our personal opinion is that we would not have had the ongoing food problems, even in the face of climate change, if Africa had over the years implemented the necessary mechanisms to develop and promote local animal genetic resources. What lies ahead in terms of climate change effect on food security in Africa is anyone's guess – but whatever it is, promoting continental adapted indigenous animal genetic resources portfolio is ready to handle it. Development and promotion of African animal genetic resources should be part of a continental strategy to transform smallholder animal production by 2050, in line with the goals of achieving the SGDs, to improve rural household food security, and bringing rural economy prosperity, resilience, sustainability, and all other desired animal related food outcomes for rural healthy diets. African animal genetic resources are the most important but underutilized resource to address the issue of ongoing food insecurity. The responsible use of local animal genetic resources through climate smart animal husbandry practices also contributes to food security, rural development and increased employment opportunities. African genetic improvement programs involving indigenous animal genetic resources must be considered as regards to local agriculture and livestock development aspirations, appropriateness to local reality and livelihood security, as well as environmental friendliness. Animal agriculture will fill in the enormous gaps in the continent's food supply if this animal group receives adequate attention and is used integrated properly in crop and livestock systems which characterize smallholder farming sector in Africa. Because they have evolved over time to accommodate the various climatic conditions and environmental pressures on the continent, Africa's native animal genetic resources are particularly resilient. Indirectly, the impact of climate change offers a chance to use native animal genetics from Africa. The use of local animal genetic diversity has the potential to substantially improve Africa's food security landscape hence should be given special consideration for sociocultural, environmental, and economic aspects, and with regard for smallholder farmer-specific factors of interest. African animal genetic resources have contributed significantly to the food and nutrition security aspects of the millions of people in their communities of origin and custody in Africa. The purpose of the perception piece is to educate the reader about the fundamental mechanisms that control the use of continental animal genetic resources and how the outlook for these mechanisms can be manipulated in the future for the benefit of improving food security in Africa. The discussion provides in-depth insight into the pertinent literature in understanding the significance of local animal genetic resources in terms of their contribution to food security in Africa.
Perspective
Open Access November 02, 2022

Using the Concept of Precedence as an Approach to Explain the Logical Interaction and Interrelationships among Corporate Social Responsibilities: Battal's CSR Train VS. Carroll ′s CSR Pyramid

Abstract Purpose: The model of CSR devised by the American scientist ″Archie B. Carroll in 1991″ - which became well- known in academic circles as Carroll′s CSR pyramid, has been criticized by academics and researchers. The researcher firmly believes that one of the most important reasons that led to the emergence of these criticisms was Carroll's adoption of the idea of the pyramid as a form to [...] Read more.
Purpose: The model of CSR devised by the American scientist ″Archie B. Carroll in 1991″ - which became well- known in academic circles as Carroll′s CSR pyramid, has been criticized by academics and researchers. The researcher firmly believes that one of the most important reasons that led to the emergence of these criticisms was Carroll's adoption of the idea of the pyramid as a form to illustrate his idea of CSR. The content of the pyramid does not match the accompanying explanations given by Carroll. Carroll's CSR pyramid does not reflect the concept of simultaneous CSRs. Also, Carroll's CSR pyramid does not reflect the logical interaction and interrelationships among CSRs. It is also noted that, Carroll's pyramid reflects the expectations of stakeholders and does not reflect the expectations of companies from their commitment to their social responsibilities. This study aimed to design a model for CSR, in which the content of its figure matches the explanations attached to it, and reflects the concept of simultaneous CSRs, in addition to the logical interaction and the interrelationship among those responsibilities. Method: The researcher used the concept of precedence as an approach to explain the logical interaction and interrelationships among CSRs. The idea of precedence is clearly found only in the railway industry. The interaction of CSRs with each other can be likened to the interaction of the components of a classic train (a cockpit and coaches). Therefore, the researcher adopted the idea of the classic train as an innovative model to address some of the shortcomings of Carroll ′s pyramid. Battal's CSR train as an innovative model- in this study, can reflect the notion of simultaneous CSRs, the logical interaction and interrelationships among CSRs, and expectations and aspirations of both stakeholders and companies. Result: By adopting the idea of the classic train work and its components, this study was able to produce a model of CSR as an alternative model for Carroll′s pyramid (1991). Originality/Value: Battal ′s CSR train is an educational model that is designed to address some of the shortcomings of Carroll's CSR pyramid "as a figure and content." The content of Battal′s CSR train matches the attached explanation, and this will help to understand how CSRs interact with each other, as well as the concept of simultaneous CSRs. It is an enrichment of the thought of CSR.
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Open Access October 05, 2022

Blockchain Technology - A Algorithm for Drug Serialization

Abstract The Blockchain technology uses different type of database that transact data in blocks and then chained each data blocks. When data fills one block, it is chained the same data onto previous block therefore, all the data blocks are stored in chronological order. The blockchain technology can help to ensure that data in supply chain is reliable, accurate and can be shared with all stakeholders [...] Read more.
The Blockchain technology uses different type of database that transact data in blocks and then chained each data blocks. When data fills one block, it is chained the same data onto previous block therefore, all the data blocks are stored in chronological order. The blockchain technology can help to ensure that data in supply chain is reliable, accurate and can be shared with all stakeholders without any manipulation. It makes supply chain more transparent and end-to-end digital visibility of data source. Blockchain is stringent technology which fill the gap between stakeholders by providing transparent unmanipulated and truthful data in supply chain. There are many initiatives has been taken by multiple regulatory bodies with partnering with supply chain stakeholders including pharmaceutical manufacturer, distributors and dispensers. In USA, Food and Drug Administration’s regulatory body Drug Supply Chain Security Act (DSCSA) initi-ated pilot program in 2019 with the partnership of leading pharmaceuticals distributors to au-thenticating saleable returns to distributor from supply chain partners. DSCSA used MediLedger blockchain interoperable technology for process evaluation and it robustness for mitigating risk of drug counterfeiting possibilities in supply chain. The DSCSA found that pilot project was suc-cessful and results were astonishing. Later it was declared that blockchain technology can also be used for meeting DSCSA’s 2023 Act for unit level traceability.
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Review Article
Open Access September 01, 2022

Dynamics of Pharmaceutical Drugs Serialization

Abstract The healthcare access is fundamental rights for every human being. It is Governments responsibility to provide good healthcare services and infrastructure to its citizen. Since last few decades, Government and healthcare industries are struggling to minimize the adverse events impacting people health due to fake medicine. The world health organization also predicted that 4 out of 10 medicines in [...] Read more.
The healthcare access is fundamental rights for every human being. It is Governments responsibility to provide good healthcare services and infrastructure to its citizen. Since last few decades, Government and healthcare industries are struggling to minimize the adverse events impacting people health due to fake medicine. The world health organization also predicted that 4 out of 10 medicines in developing and poor countries are either fake or potentially adulterated. Counterfeit drugs cost billions of dollars deficit to world economy and reduce research and development (R&D) funds allocation from organizations. Stopping counterfeit medicine into supply chain is main challenge for Government and regulatory authorities. The Government and regulatory authorities are now making stringent guidelines to prohibit criminals and counterfeiters to supply fake medicine in markets. Healthcare industry need stringent regulations and secure technologies provide sage and authentic drugs to patients. The FDA has published the 10 years roadmap to implement the drug traceability in United States. The Healthcare Distribution Alliance (HDA) has also mandated to print several barcodes and human readable data in product packaging hierarchy. The FDA is participating in pilot project with leading pharmaceutical drug manufacturer and wholesales to use blockchain technology in interoperable digital network for securing digital traceability data transfer between authorized trading partners.
Review Article
Open Access August 08, 2022

Motives of Tourists': Socio-Economic and Challenges of Kwahu Easter Festival (KEF) in Ghana

Abstract The purpose of the study was to examine the Motives of Tourists; Socio-Economic and Challenges of tourism in Kwahu in the Eastern Region of Ghana The study adopted a descriptive survey research design. The population of the study comprised six (6) communities (Mpraeso, Atibie, Obomeng, Obo Oworobong, and Nketepa in Kwahu South District Assembly (KSDA) in the Eastern Region of Ghana. Purposive and [...] Read more.
The purpose of the study was to examine the Motives of Tourists; Socio-Economic and Challenges of tourism in Kwahu in the Eastern Region of Ghana The study adopted a descriptive survey research design. The population of the study comprised six (6) communities (Mpraeso, Atibie, Obomeng, Obo Oworobong, and Nketepa in Kwahu South District Assembly (KSDA) in the Eastern Region of Ghana. Purposive and convenient sampling techniques were employed to select two hundred (200) respondents for the study. The main instrument used for data collection was questionnaires. The study employed the statistical package for social sciences (SPSS) to code and process the collected data. Descriptive and relational statistical techniques involving frequencies, percentages, summations, diagrams, and tables were employed in analysing the data. The Chi-square test analysis was used to explore the relationships and differences in perceptions. The study indicated that every tourist, whether local (Ghanaian) or foreign, had at least one of the following motives in mind for participating in the festival; To socialize; For relaxation; For education to participate and witness the paragliding festivals; To take photographs of festival scenes; Other motives like to sell items, especially souvenirs. The study also revealed that the KEF has had some positive socio-economic impact or implications on the area. These among others include: job creation, income generation for locals of the area, infrastructural development, and projection of the image of the area as the festival has become one of the biggest gatherings of revellers in the country, drawing people from all walks of life, nationally and internationally as a result of the introduction of paragliding since 2005, socialization enhancement, medium for cultural exchange and education, and finally serves as a medium for portraying the cultural identity of the people of Kwahu. The study also indicated that the major challenges encountered by tourists during the event were listed in order of degree of intensity: High cost of living, poor road network in the area, intermitted electricity and water supply, poor sanitary conditions in the area, poor health facilities, and unwelcoming attitude of some local residents of the festival area. It is recommended that, residents must be educated about the potential benefits of tourism as an industry helping to achieve sustainable community development. It is also recommended that Ghana tourism authority and Kwahu District Assembly should collaborate to improve on social amenities in the municipality to attract more foreign and local tourists during the festivity.
Article
Open Access June 26, 2022

Role of Electronic Components in Computing

Abstract Electronics and computer engineering is a scientific and technical field in which electronic and computer systems are studied and their use. They are related to the technical professions within which electronic devices, systems, and computer programs are realized. The past half-century has been greatly marked by the development of electronics, computing, and their application in communications, [...] Read more.
Electronics and computer engineering is a scientific and technical field in which electronic and computer systems are studied and their use. They are related to the technical professions within which electronic devices, systems, and computer programs are realized. The past half-century has been greatly marked by the development of electronics, computing, and their application in communications, medicine, and industry. This field has become the fundamental technical infrastructure of modern society. Today, there is almost no electronic device that does not use an electronic computer, and there is also not a single computer that is almost exclusively made of electronic components. This article explores the need for electronic components in digital computing.
Tutorial
Open Access May 09, 2022

Study for Some Body Weight and Egg Traits in Domyati and Khaki-Campbell Ducks

Abstract The duck industry makes an important contribution to the availability of animal protein sources in Egypt, little known about the genetic parameters, particularly the heritability and genetic correlations of body weight and egg production in ducks. Body weight is the most essential feature for genetic improvement due to its ease of selection, high heredity, and large impact on meat production [...] Read more.
The duck industry makes an important contribution to the availability of animal protein sources in Egypt, little known about the genetic parameters, particularly the heritability and genetic correlations of body weight and egg production in ducks. Body weight is the most essential feature for genetic improvement due to its ease of selection, high heredity, and large impact on meat production costs. The target of this study was to evaluate and explain genetic parameters such as the heritability, the genetic and phenotypic correlations, and sire breeding value in Domyati (local) and Khaki-Campbell (foreign) ducks in order to improve body weight and egg traits. A total of 160 (80 Domyati and 80 Khaki-Campbell ducks utilized to measure body weight at 16 and 20 weeks g), as well as 7000 eggs (2500 Domyati and 4500 Khaki-Campbell) to measure egg traits (the egg number, egg weight, and egg mass are all measured throughout the first 90 days of laying). In Domyati and Khaki-Campbell ducks, the heritability estimated for body weight was moderate to high, ranged from 0.35 to 0.40, and 0.21 to 0.30 for egg production. The genetic correlations among body weight and egg traits were all positive and had high values, also among BW16 and BW20 were stronger (0.90); (0.99). So the genetic improvement in BW16 could be followed by an increase in BW20 weeks. It concluded that, the relatively high value of genetic heritability for body weights and egg traits in Domyati and Khaki-Campbell ducks, indicates that it is possible to genetically increase body weight and egg traits through selection and subsequently inbreeding to divide the herd into groups that are selected among themselves to keep their sons.
Article
Open Access April 18, 2022

Preliminary Survey Analysis on Food Choices among Randomly Selected Social Media Users amidst COVID-19 Pandemic in Nigeria

Abstract A survey on food choices with a randomized sample population of individuals using various social media in Nigeria was conducted during the COVID1-19 pandemic. The data generated was subjected to basic standard statistical analysis. The parameters indicated that 94% of the population is young adults, 58.9 % percent are city dwellers, 63.6% are students, 23.4 % are into business, 86.9% are [...] Read more.
A survey on food choices with a randomized sample population of individuals using various social media in Nigeria was conducted during the COVID1-19 pandemic. The data generated was subjected to basic standard statistical analysis. The parameters indicated that 94% of the population is young adults, 58.9 % percent are city dwellers, 63.6% are students, 23.4 % are into business, 86.9% are graduates; 73.8% consume various diets, 23.4% are vegetarians and only 2.8% fed only on proteins, 30.8% of them go on two meals per day. The most choices on influence on food purchases decision are hunger (26.2%), mood (26.2%), past experience (45.8%), quality of the food products (66.7%), cost of the food products (50.5%) and government approval (28%). Also,other most preferred choices are for self-prepared food (40.21%), enhanced local diets (36 %), and a blend of foreign and local diets purchases (24%). Other highest choices include: easy preparation (37.4%), shelf life (29%); cute packaging (23.4%), swelling property preference (20.6%), minimal cooking time and energy preference (37.4%). The weighted sum, index and rank on factors influencing food choices showed that the influence of quality of food product ranked highest, followed by influence on cost. Also preference for enhanced local healthy diets to foreign ranked highest, minimal cooking time and energy costs ranked highest. These nutritional adaptations have implications to individuals, food scientists, manufacturers in the food industry, food regulatory agencies, government and other decision bodies.
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Open Access October 19, 2021

A Ligthweight Wayfinding Assistance System for IoT Applications

Abstract In this paper, we propose to design an indoor sign detection system for industry 4.0. In order to implement the proposed system, we proposed a lightweight deep learning-based architecture based on MobileNet which can be run on embedded devices used to detect and recognize indoor landmarks signs in order to assist blind and sighted during indoor navigation. We apply various operations in order to [...] Read more.
In this paper, we propose to design an indoor sign detection system for industry 4.0. In order to implement the proposed system, we proposed a lightweight deep learning-based architecture based on MobileNet which can be run on embedded devices used to detect and recognize indoor landmarks signs in order to assist blind and sighted during indoor navigation. We apply various operations in order to minimize the network size as well as computation complexity. Internet of things (IoT) presents a connection between internet and the surroundings objects. IoT is characterized to connect physical objects with their numerical identities and enables them to connect with each other. This technique creates a kind of bridge between the physical world and the virtual world. The paper provides a comprehensive overview of a new method for a set of landmark indoor sign objects based on deep convolutional neural network (DCNN) for internet of things applications.
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Open Access September 24, 2021

Hydrogen Industry: A Technical, Economic, and Market Analysis Overview

Abstract Like electricity, hydrogen is an excellent energy carrier, as it can be produced from many different and abundant precursors, such as natural gas, coal, water, and renewable energy. The use of hydrogen in fuel cells, particularly in the transport sector, will make it possible to diversify the energy supply, take advantage of domestic resources, and reduce oil imports dependence. Unlike other [...] Read more.
Like electricity, hydrogen is an excellent energy carrier, as it can be produced from many different and abundant precursors, such as natural gas, coal, water, and renewable energy. The use of hydrogen in fuel cells, particularly in the transport sector, will make it possible to diversify the energy supply, take advantage of domestic resources, and reduce oil imports dependence. Unlike other fuels, hydrogen (H2) can be generated and consumed without emitting carbon dioxide (CO2). This results in great ecological benefits and fundamental challenges. Hydrogen can operate in a closed and inexhaustible cycle based on the cleanest, most abundant, and elemental substances: water, oxygen, and hydrogen. If hydrogen is generated using light, heat, and electricity produced from solar, wind, or nuclear energy, hydrogen becomes a versatile and universal means of storing and transporting energy and a necessary element for future energy systems that operate without environmental pollution, CO2, and other gases that contribute to the greenhouse effect. Hydrogen is necessary to eliminate environmental pollution and stabilize the composition of the planet’s atmosphere and climate. This paper investigates different methods of hydrogen production in the term of their technological and economic aspects. This paper shows that thermochemical methods dominate the hydrogen market while emerging electroreduction methods are developing fast, which might turn the tide in the future.
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Open Access August 14, 2021

Complex Energy Conversion System Analysis: An Overview

Abstract This article describes the optimization models recently applied to the design and operation of power systems towards forming smart grids and identifies trends, barriers, and possible gaps in this area. Models are described to optimize the design and operation of power systems considering renewable energies, distributed generation, microgrids, demand management, and energy storage systems. It was [...] Read more.
This article describes the optimization models recently applied to the design and operation of power systems towards forming smart grids and identifies trends, barriers, and possible gaps in this area. Models are described to optimize the design and operation of power systems considering renewable energies, distributed generation, microgrids, demand management, and energy storage systems. It was concluded that it is necessary to validate many of the models formulated recently to optimize the operation through tests with real data and on a large scale. Furthermore, demand management and microgrids are aspects in which it is necessary to develop models for optimal power flow. Finally, it is necessary to predict stochastic variables with greater precision so that these models adapt to the real behavior of the system.
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Open Access August 14, 2021

An Economic Evaluation of the use of Wind Farms in Iran, Taking into Account the Effect of Energy Price Liberalization Policy

Abstract In this study, the effect of energy cost liberalization policies on the cost-effectiveness of wind farms compared to gas power plants has been investigated. To calculate the cost of electricity generation from various sources, including wind energy and fossil fuels, the “levelized cost” method has been used as the most acceptable economic method to compare different types of electricity generation [...] Read more.
In this study, the effect of energy cost liberalization policies on the cost-effectiveness of wind farms compared to gas power plants has been investigated. To calculate the cost of electricity generation from various sources, including wind energy and fossil fuels, the “levelized cost” method has been used as the most acceptable economic method to compare different types of electricity generation technologies. In addition, calculations related to the cost of electricity, different fuel prices, different technologies of wind farms, and different prices of different types of fuel are considered. Based on the results of this research, it was found that by targeting fuel prices in the country, wind farms are quite cost-effective, and considering the cost of the opportunity to use diesel in the country, the construction of these power plants can provide the possibility of exporting this fuel. This cost also increases with the production of valuable equipment in the country. The important point is that the macro policy should localize the wind turbine industry with priority to its valuable parts and components due to fuel price changes. This policy will continue to make this type of power plant cost-effective in the country and the employment of specialists in the country.
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Open Access July 30, 2021

Air of Uncertainty from Pollution Profiteers: Status of Ambient Air Quality of Sawmill Industry in Ilorin Metropolis, Kwara State, Nigeria

Abstract We can’t stop breathing, but we can do something about the quality of air that we breathe. Clean fresh air is indispensable ingredient for a good life quality. Individuals poses the right towards expecting that the breathed air will not harm people. Thus, fighting air pollution will not only improve health outcomes, productivity, and well-being, it’s also essential toward reducing the emissions of [...] Read more.
We can’t stop breathing, but we can do something about the quality of air that we breathe. Clean fresh air is indispensable ingredient for a good life quality. Individuals poses the right towards expecting that the breathed air will not harm people. Thus, fighting air pollution will not only improve health outcomes, productivity, and well-being, it’s also essential toward reducing the emissions of greenhouse gas as well as fighting climate change. For examples, a third of the global population is at risk from unhealthy of ambient air pollutants concentrations, with the loss of approximately 6.4 million healthy-life-years attributed specifically to chronic exposure to ambient particulate matter. Expert panels have consistently rated air pollution as a greater health hazard than water pollution. Pollution of air is the leading source of unexplained and undiagnosed diseases, besides have remained associated with a variety of serious human health risks, and in fact, a threshold has not been established under which these pollutants exert no adverse effects. This study evaluates ambient air quality at major sawmill sites in Ilorin Metropolis, Kwara State, Nigeria. “Measurements of Air pollution were accurately carried out using direct reading, automatic in situ gas monitors; Hand held mobile multi-gas monitor with model AS8900 [Combustible (LEL), and Oxygen (O2)], BLATN with model BR – Smart Series air quality monitor (PM10, Formaldehyde) and air quality multimeter with model B SIDE EET100 (Dust (PM2.5), VOC, Temperature and Relative Humidity)”. The outcomes disclosed among others, the average concentrations of CO, O2 as well as other measured parameters for instance formaldehyde (HcHo) etc., they are also consistently low as well as within acceptable range in terms of National as well as Global monitoring standards for air quality indices. However, there are few exceptions for instance the average volatile organic compounds (VOCs) concentrations, PM2.5, PM10 as well as Combustible (LEL) respectively, which are higher when compared to National and Global standards. This high figure is due to pollutant amount existing in the sawmills air environment resulting from input of influents from activities of the sawmill. However, as a result, air pollution in the city of Ilorin is found to be increasingly polluted and are of major health concern because of their synergistic action. Due to the high evidences and values, it can lead to a remarkable rise in over-all figure of hospital visits/ patients’ admissions with acute respiratory illnesses as soon as air pollutants level remained high. Hence, there is the need for an aggressive control of ambient air pollution.
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Open Access December 27, 2021

Leveraging AI and ML for Enhanced Efficiency and Innovation in Manufacturing: A Comparative Analysis

Abstract The manufacturing industry has embraced modern technologies such as big data, machine learning, and artificial intelligence. This paper examines AI and machine learning developments in the manufacturing industry, comparing current practices and data-driven projects. It aims better to understand these technologies and their potential benefits and challenges. The research identifies opportunities [...] Read more.
The manufacturing industry has embraced modern technologies such as big data, machine learning, and artificial intelligence. This paper examines AI and machine learning developments in the manufacturing industry, comparing current practices and data-driven projects. It aims better to understand these technologies and their potential benefits and challenges. The research identifies opportunities for innovative business solutions and explores industry practices and research results. The paper focuses on implementation rather than technical aspects, aiming to enhance knowledge in this area.
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Open Access August 29, 2022

From Deterministic to Data-Driven: AI and Machine Learning for Next-Generation Production Line Optimization

Abstract The advancement of modern manufacturing is synonymous with the growth of automation. Automation replaces human operators, improves productivity and quality, and reduces costs. However, the initial financial cost and knowledge requirements can be barriers to embracing automation. Manufacturers are now seeking smart manufacturing, known as the fourth industrial revolution. Smart manufacturing goes [...] Read more.
The advancement of modern manufacturing is synonymous with the growth of automation. Automation replaces human operators, improves productivity and quality, and reduces costs. However, the initial financial cost and knowledge requirements can be barriers to embracing automation. Manufacturers are now seeking smart manufacturing, known as the fourth industrial revolution. Smart manufacturing goes beyond automation and utilizes IoT, AI, and big data for optimized production. In a smart factory, production can be linked and controlled innovatively, leading to increased performance, agility, and reduced costs.
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Open Access October 15, 2022

Big Data and AI/ML in Threat Detection: A New Era of Cybersecurity

Abstract The unrelenting proliferation of data, entwined with the prevalence of mobile devices, has given birth to an unprecedented growth of information obscured by noise. With the Internet of Things and myriad endpoint devices generating vast volumes of sensitive and critical data, organizations are tasked with extracting actionable intelligence from this deluge. Governments and enterprises alike, even [...] Read more.
The unrelenting proliferation of data, entwined with the prevalence of mobile devices, has given birth to an unprecedented growth of information obscured by noise. With the Internet of Things and myriad endpoint devices generating vast volumes of sensitive and critical data, organizations are tasked with extracting actionable intelligence from this deluge. Governments and enterprises alike, even under pressure from regulatory boards, have strived to harness the power of data and leverage it to enhance safety and security, maximize performance, and mitigate risks. However, the adversaries themselves have capitalized on the unequal battle of big data and artificial intelligence to inflict widespread chaos. Therefore, the demand for big data analytics and AI/ML for high-fidelity intelligence, surveillance, and reconnaissance is at its highest. Today, in the cybersecurity realm, the detection of adverse incidents poses substantial challenges due to the sheer variety, volume, and velocity of deep packet inspection data. State-of-the-art detection techniques have fallen short of detecting the latest attacks after a big data breach incident. On the other hand, computational intelligence techniques such as machine learning have reignited the search for solutions for diverse monitoring problems. Recent advancements in AI/ML frameworks have the potential to analyze IoT/edge-generated big data in near real-time and assist risk assessment and mitigation through automated threat detection and modeling in the big data and AI/ML domain. Industry best practices and case studies are examined that endeavor to showcase how big data coupled with AI/ML unlocks new dimensions and capabilities in improved vigilance and monitoring, prediction of adverse incidents, intelligent modeling, and future uncertainty quantification by data resampling correction. All of these avenues lead to enhanced robustness, security, safety, and performance of industrial processes, computing, and infrastructures. A view of the future and how the potential threats due to the misuse of new technologies from bandwidth to IoT/edge, blockchain, AI, quantum, and autonomous fields is discussed. Cybersecurity is again playing out at a pace set by adversaries with low entry barriers and debilitating tools. The need for innovative solutions for defense from the emerging threat landscape, harnessing the power of new technologies and collaboration, is emphasized.
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Open Access December 27, 2021

Sustainability in Construction: Exploring the Development of Eco-Friendly Equipment

Abstract The equipment used in the construction industry is usually associated with a high impact on the environment. Although sustainable design has shown to be a main player among the initiatives focused on reducing environmental impact, it has been driven by the workers and processes, leaving the equipment endeavors in more restrictive and later stages. The equipment industry has been a constant target [...] Read more.
The equipment used in the construction industry is usually associated with a high impact on the environment. Although sustainable design has shown to be a main player among the initiatives focused on reducing environmental impact, it has been driven by the workers and processes, leaving the equipment endeavors in more restrictive and later stages. The equipment industry has been a constant target of environmental standards and economic pressure, but the increasing technological development allows it to respond to sustainability and safety expectations while enhancing its performance. However, there are still several limitations that lead this sector to be one of the last to reach upgrading levels in terms of development. A study identified some gaps in the equipment design that require a greater effort to effectively support the workers and companies towards sustainable construction. This chapter is based on a study aiming to understand the consolidated knowledge of technologically sustainable equipment design and to identify the challenges left for its full development. The findings support the development of innovative eco-friendly equipment, taking into consideration sustainable materials and product guidelines, as well as green economy initiatives. It also supports complex system approaches and safety by design specificities to establish a corporate knowledge of sustainable equipment and align it with the new regulations of the construction industry. The chapter introduces the context of construction equipment in terms of new challenges when faced with the need to provide construction work with a greater capacity for safety, from an environmental and energy efficiency perspective, and within the paradigm of sustainability. Then, it presents the concept of sustainable equipment considering its principles, followed by a characterization of the agents involved in its life cycle.
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Open Access December 27, 2021

Financial Implications of Predictive Analytics in Vehicle Manufacturing: Insights for Budget Optimization and Resource Allocation

Abstract Factory owners and vehicle manufacturers increasingly opt for predictive analytics to inform their decisions. While predictive analytics have been proven to provide insights into the initiation of maintenance measures before a machine actually fails, the right models and features could have a significant impact on the budget spent and resources allocated. This means that financially oriented [...] Read more.
Factory owners and vehicle manufacturers increasingly opt for predictive analytics to inform their decisions. While predictive analytics have been proven to provide insights into the initiation of maintenance measures before a machine actually fails, the right models and features could have a significant impact on the budget spent and resources allocated. This means that financially oriented questions need to at least partially guide the decisions in the planning phase of data science projects. Data-driven approaches will play an increasingly important role, but only a few of the firms that were confident performed logistic regression models for predictive maintenance. Also, from the available knowledge, data-driven classification models connecting vehicle component failures and the occurrence of delays at the assembly line have not been published. This paper utilizes a real-world data-driven approach using classification models in predictive analytics by vehicle manufacturers and thereby links the financial implications of such data science projects to their results. We expand the existing literature on predictive maintenance and possess a unique dataset of newly launched series of vehicles, presented as-is. Our research context is of interest to researchers and practitioners in the automotive industry that manage and plan the final vehicle assembly with just-in-time principles, factoring the consequences of component failures on the assembly process. Key findings of this paper highlight that while minor tweaking of the models is possible, their potential input in decision-making processes for budget optimization is limited.
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Open Access November 16, 2023

Innovations in Agricultural Machinery: Assessing the Impact of Advanced Technologies on Farm Efficiency

Abstract Progress in the development and adoption of technological innovations is instrumental in enhancing the efficiency of production systems across the globe. Through the introduction of cost-efficient and high-performing technologies, countries can both reduce the resource use intensity of their economies and boost the global supply of essential products. The focus of this study is to analyze the [...] Read more.
Progress in the development and adoption of technological innovations is instrumental in enhancing the efficiency of production systems across the globe. Through the introduction of cost-efficient and high-performing technologies, countries can both reduce the resource use intensity of their economies and boost the global supply of essential products. The focus of this study is to analyze the application of advanced machinery and mechanisms within the agricultural sector, a primary industry that acts as a major contributor to the gross domestic product (GDP) of many nations. Specifically, this paper provides an in-depth review of the latest impact assessments based on analytical and modeling tools conducted on agricultural machinery and production technologies. Our findings highlight the positive role played by scientific progress and innovation in driving the competitiveness, growth and improved sustainability of the agricultural sector. Over the years, advanced technologies have accelerated the development and modernization of machinery, equipment, and processes in farming. Typically, modern machinery and equipment have enabled large-scale production on farms, enhancing the cost-efficient use of both land and labor, as well as the capacity and timeliness in performing essential agricultural operations. The rapid diffusion of technical advancements has further contributed to resource savings, productivity growth, and the overall transformation of agricultural value chains. Accordingly, the implementation of appropriate enabling conditions is of vital importance in encouraging the widespread integration of technologies in agriculture, not only boosting productivity along the agri-food chain but also yielding widespread social, economic, and environmental benefits.
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Open Access November 16, 2023

Zero Carbon Manufacturing in the Automotive Industry: Integrating Predictive Analytics to Achieve Sustainable Production

Abstract This charge-ahead paper suggests that transitioning the automotive industry towards a zero-carbon ecosystem from material to end-of-life can be accomplished through disruptive zero-carbon manufacturing in the broad area of all-electric vehicle production technology. To accomplish zero carbon emission automotive manufacturing in the vehicle assembly domain, future paradigms must converge on the [...] Read more.
This charge-ahead paper suggests that transitioning the automotive industry towards a zero-carbon ecosystem from material to end-of-life can be accomplished through disruptive zero-carbon manufacturing in the broad area of all-electric vehicle production technology. To accomplish zero carbon emission automotive manufacturing in the vehicle assembly domain, future paradigms must converge on the decoupling of carbon dioxide emissions from automobile manufacturing and use the design, processing, and manufacturing conditions. The envisioned zero carbon emission vehicle manufacturing domain consists of two complementary components: (a) making more efficient use of energy and (b) reducing carbon in energy use. This paper presents the status of key scientific and technological advancements to bring the manufacturing model of today to a zero-carbon ecosystem for the entire automotive industry of tomorrow. This paper suggests the groundbreaking application of dynamic and distributed predictive scheduling algorithms and open sensing and visualization technology to meet the zero carbon emission vehicle manufacturing goals. Power-aware high-performance computing clusters have recently become a viable solution for sustainable production. Advances in scalable and self-adaptive monitoring, predictive analytics, timeline-based machine learning, and digital replica of cyber-physical systems are also seen co-evolving in the zero carbon manufacturing future. These methods are inspired by initiatives to decouple gross domestic product growth and energy-related carbon dioxide emissions. Stakeholders could co-design and implement shared roadmaps to transition the automotive manufacturing sector with relevant societal and environmental benefits. The automated mobility sector offers a program, an industry-leading example of transforming an automotive production facility to carbon neutrality status. The conclusions from this paper challenge automotive manufacturers to engage in industry offsetting and carbon tax programs to drive continuous improvement and circular vehicle flows via a multi-directional zero-carbon smart grid.
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Open Access December 27, 2020

Enhancing Pharmaceutical Supply Chain Efficiency with Deep Learning-Driven Insights

Abstract The growing complexity of the operating environment urges pharmaceutical innovation. This essay addresses the need for the integration of advanced technologies in the pharmaceutical supply chain. It justifies the value proposition and presents a concrete use case for the integration of deep learning insights to make data-driven decisions. The supply chain has always been a priority for the [...] Read more.
The growing complexity of the operating environment urges pharmaceutical innovation. This essay addresses the need for the integration of advanced technologies in the pharmaceutical supply chain. It justifies the value proposition and presents a concrete use case for the integration of deep learning insights to make data-driven decisions. The supply chain has always been a priority for the pharmaceutical industry; research and development recognizes companies' increasing investment in big data strategies, with plans for a CAGR in big data tool adoption. The work presented herein has a preliminary explorative character to recuperate and integrate evidence from partly overlooked practical experience and know-how. The practical relevance of the essay is directed toward practitioners in pharmaceutical production, supply chain management, logistics, and regulatory agencies. The literature has shown a long-term concern for enhanced performance in the pharmaceutical supply chain network. This essay demonstrates the application of deep learning-driven insights to reveal non-evident flow dependencies. The main aim is to present a comprehensive insight into deep learning-driven decision support. The supply chain is portrayed in a holistic manner, seeking end-to-end visibility. Implications for public policy are discussed, such as data equity: many countries are protecting their populations and economic growth by building resilience and efficiency to ensure the capacity to move goods across supply chains. The implementation strategy is covered. The combined reduction of variability, efficiency as matured richness, reliability (on stochastic flows and their understanding through deep learning and data), and system noise (increased dampening through the inclusiveness of all stakeholders) results in increased responsiveness of supply chains for pharmaceutical products. Future work involves the integration of external data, closing the loop between planning and its application in reality.
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Open Access December 27, 2021

Predictive Analytics and Deep Learning for Logistics Optimization in Supply Chain Management

Abstract Managing supply chains efficiently has become a major concern for organizations. One of the important factors to optimize in supply chain management is logistics. The advent of technology and the increase in data availability allow for the enhancement of the efficiency of logistics in a supply chain. This discussion focuses on the blending of analytics with innovation in logistics to improve the [...] Read more.
Managing supply chains efficiently has become a major concern for organizations. One of the important factors to optimize in supply chain management is logistics. The advent of technology and the increase in data availability allow for the enhancement of the efficiency of logistics in a supply chain. This discussion focuses on the blending of analytics with innovation in logistics to improve the operations of a supply chain. An approach is presented on how predictive analytics can be used to improve logistics operations. In order to analyze big data in logistics effectively, an artificial intelligence computational technique, specifically deep learning, is employed. Two case studies are illustrated to demonstrate the practical employability of the proposed technique. This reveals the power and potential of using predictive analytics in logistics to project various KPI values ahead in the future based on the contemporary data from the logistics operations; sheds light on the innovative technique of employing deep learning through deep learning-based predictive analytics in logistics; suggests incorporating innovative techniques like deep learning with predictive analytics to develop an accurate forecasting technique in logistics and optimize operations and prevent disruption in the supply chain. The network of supply chains has become more complex, necessitating the need for the latest technological advancements. The sectors that have gained a fair amount of attention for the application of technology to optimize their operations are manufacturing, healthcare, aerospace, and the automotive industry. A little attention has been diverted to the logistics sector; many describe how analytics and artificial intelligence can be used in the logistics sector to achieve higher optimization. Currently, significant research has been done in optimizing logistics operations. Nevertheless, with the explosive volume of historical data being produced by the logistics operations of an organization, there is a great opportunity to learn valuable insights from the data accumulated over time for more long-term strategic planning. To develop the logistics operations in an organization, the use of historical data is essential to understand the trends in the operations. For example, regular maintenance planning and resource allocation based on trends are long-term activities that will not affect logistics operations immediately but can affect the business’s strategic planning in the long run. A predictive analysis technique employed on historical data of logistics can narrow down conclusions based on the future trends of logistics operations. Thus, the technique can be used to prevent the disruption of the supply chain.
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