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Open Access January 11, 2025

Exploring LiDAR Applications for Urban Feature Detection: Leveraging AI for Enhanced Feature Extraction from LiDAR Data

Abstract The integration of LiDAR and Artificial Intelligence (AI) has revolutionized feature detection in urban environments. LiDAR systems, which utilize pulsed laser emissions and reflection measurements, produce detailed 3D maps of urban landscapes. When combined with AI, this data enables accurate identification of urban features such as buildings, green spaces, and infrastructure. This synergy is [...] Read more.
The integration of LiDAR and Artificial Intelligence (AI) has revolutionized feature detection in urban environments. LiDAR systems, which utilize pulsed laser emissions and reflection measurements, produce detailed 3D maps of urban landscapes. When combined with AI, this data enables accurate identification of urban features such as buildings, green spaces, and infrastructure. This synergy is crucial for enhancing urban development, environmental monitoring, and advancing smart city governance. LiDAR, known for its high-resolution 3D data capture capabilities, paired with AI, particularly deep learning algorithms, facilitates advanced analysis and interpretation of urban areas. This combination supports precise mapping, real-time monitoring, and predictive modeling of urban growth and infrastructure. For instance, AI can process LiDAR data to identify patterns and anomalies, aiding in traffic management, environmental oversight, and infrastructure maintenance. These advancements not only improve urban living conditions but also contribute to sustainable development by optimizing resource use and reducing environmental impacts. Furthermore, AI-enhanced LiDAR is pivotal in advancing autonomous navigation and sophisticated spatial analysis, marking a significant step forward in urban management and evaluation. The reviewed paper highlights the geometric properties of LiDAR data, derived from spatial point positioning, and underscores the effectiveness of machine learning algorithms in object extraction from point clouds. The study also covers concepts related to LiDAR imaging, feature selection methods, and the identification of outliers in LiDAR point clouds. Findings demonstrate that AI algorithms, especially deep learning models, excel in analyzing high-resolution 3D LiDAR data for accurate urban feature identification and classification. These models leverage extensive datasets to detect patterns and anomalies, improving the detection of buildings, roads, vegetation, and other elements. Automating feature extraction with AI minimizes the need for manual analysis, thereby enhancing urban planning and management efficiency. Additionally, AI methods continually improve with more data, leading to increasingly precise feature detection. The results indicate that the pulse emitted by continuous wave LiDAR sensors changes when encountering obstacles, causing discrepancies in measured physical parameters.
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Open Access January 10, 2025

Artificial Immune Systems: A Bio-Inspired Paradigm for Computational Intelligence

Abstract Artificial Immune Systems (AIS) are bio-inspired computational frameworks that emulate the adaptive mechanisms of the human immune system, such as self/non-self discrimination, clonal selection, and immune memory. These systems have demonstrated significant potential in addressing complex challenges across optimization, anomaly detection, and adaptive system control. This paper provides a [...] Read more.
Artificial Immune Systems (AIS) are bio-inspired computational frameworks that emulate the adaptive mechanisms of the human immune system, such as self/non-self discrimination, clonal selection, and immune memory. These systems have demonstrated significant potential in addressing complex challenges across optimization, anomaly detection, and adaptive system control. This paper provides a comprehensive exploration of AIS applications in domains such as cybersecurity, resource allocation, and autonomous systems, highlighting the growing importance of hybrid AIS models. Recent advancements, including integrations with machine learning, quantum computing, and bioinformatics, are discussed as solutions to scalability, high-dimensional data processing, and efficiency challenges. Core algorithms, such as the Negative Selection Algorithm (NSA) and Clonal Selection Algorithm (CSA), are examined, along with limitations in interpretability and compatibility with emerging AI paradigms. The paper concludes by proposing future research directions, emphasizing scalable hybrid frameworks, quantum-inspired approaches, and real-time adaptive systems, underscoring AIS's transformative potential across diverse computational fields.
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Article
Open Access November 26, 2024

Impact of Classroom from the Primary Level of the Acquisition of English as a Second Language in Bangladesh

Abstract This paper examines the impact of primary level classroom environments on the acquisition of English as a second language (L2) in Bangladesh, comparing English-medium and Bangla-medium schools. The study investigates how different instructional approaches and early exposure to English influence language proficiency among students. Through a mixed-methods approach, including surveys, interviews, [...] Read more.
This paper examines the impact of primary level classroom environments on the acquisition of English as a second language (L2) in Bangladesh, comparing English-medium and Bangla-medium schools. The study investigates how different instructional approaches and early exposure to English influence language proficiency among students. Through a mixed-methods approach, including surveys, interviews, and proficiency tests, the research reveals significant differences in language acquisition outcomes between the two educational settings. Findings indicate that students in English-medium schools, who are exposed to Natural approach methods of language learning and immersive English-speaking environments, demonstrate higher proficiency in speaking and listening skills compared to their Bangla-medium counterparts, who primarily receive grammar-focused instruction. The study highlights the critical role of early exposure to English, with students who begin learning the language at a younger age showing better phonological and syntactic development. Additionally, the integration of technology in language teaching emerges as a valuable tool for enhancing language learning, particularly in contexts with limited classroom exposure. The research suggests that Bangla-medium schools could benefit from adopting more interactive, student-centered teaching methods and integrating digital tools to support practical language use. The study's findings have significant implications for educational policy, advocating for a shift towards more immersive and communicative teaching practices to improve English language acquisition in Bangladesh. This research contributes to the broader understanding of SLA and offers practical recommendations for enhancing language education in similar contexts.
Article
Open Access July 24, 2023

Role of Oncology Nurse Navigators: An Integrative Review

Abstract Background: Oncology nurse navigators (ONNs) are becoming even more vital as healthcare continues to develop into a more complicated, confusing maze for patients. When many specialists on the treatment team have divergent points of view due to the nature of their respective professions or other factors, the patient may experience feelings of confusion. In the end, this can cause delays in [...] Read more.
Background: Oncology nurse navigators (ONNs) are becoming even more vital as healthcare continues to develop into a more complicated, confusing maze for patients. When many specialists on the treatment team have divergent points of view due to the nature of their respective professions or other factors, the patient may experience feelings of confusion. In the end, this can cause delays in treatment, pose a threat to the established standard of care, and lead to a decrease in patient satisfaction. Aim: To enumerate various ways in which ONNs may help improve the quality of life of cancer patients. Design: An integrative review. Results: A total of 19 studies related to the topic are evaluated. Four main themes namely: provider of psychological support, facilitator of timely care, oncology nurse navigators perception of their role and patient’s perception of oncology nurse navigators and 3 sub themes which are: information giver, source of emotional support and coordinator, were identified to be the roles of the ONNs. The findings showed that oncology nurse navigators help reduce patients anxiety and distress, increase patient satisfaction, shorten the time from diagnosis to treatment, provide necessary information, support them emotionally and coordinate their care with the different members of the healthcare team and resources. Conclusion: The main function of the ONNs is to address any barrier that may hinder the patient’s cancer treatment, survivorship and even palliative care. ONNs make sure that each patient has individualized nursing care according to the patients and their families' needs. Implications for Practice: ONNs have the potential to significantly contribute not only to the quality of life of cancer patients but also to the process of achieving better service integration. The result of this integrative review contributes to the growth of the healthcare system by improving accessibility, fairness, efficiency, effectiveness, and the ability to maintain health services throughout time brought about by ONNs.
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Review Article
Open Access December 22, 2025

Reimagining Mathematical Modeling for a Responsive and Integrated Future in Infectious Disease Epidemiology

Abstract Mathematical modeling plays a central role in infectious disease epidemiology, shaping outbreak response strategies and informing public health policy. The COVID-19 pandemic demonstrated the value of these models but also exposed persistent limitations related to data fragility, lack of transparency, limited stakeholder engagement, and insufficient consideration of social and political contexts. [...] Read more.
Mathematical modeling plays a central role in infectious disease epidemiology, shaping outbreak response strategies and informing public health policy. The COVID-19 pandemic demonstrated the value of these models but also exposed persistent limitations related to data fragility, lack of transparency, limited stakeholder engagement, and insufficient consideration of social and political contexts. Rather than critiquing modeling as a discipline, this perspective argues for a reorientation of infectious disease modeling toward a more responsive, equity-centered, and participatory paradigm. We propose a conceptual framework built on three interrelated principles: adaptability through real-time data integration, transparency via open-source and reproducible practices, and relevance through interdisciplinary and co-produced model design. Drawing on illustrative examples from COVID-19 and dengue control efforts, we highlight how integrating behavioral dynamics, local knowledge, and policy feedback can improve model usefulness and public trust. Reconceptualizing models as dynamic systems of inquiry rather than static forecasting tools can enhance decision-making and promote more equitable and effective responses to future public health emergencies.
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Brief Review
Open Access October 06, 2025

The symbolism and cultural significance of “Tuei” beverage among the Fantes in Ghana

Abstract Background: Traditional foods, once carriers of cultural identity and heritage, are being quietly replaced as globalization and modern ideals redefine the choices of younger generations. This ethnographic study investigated the cultural meaning and symbolism of Tuei, an indigenous maize-based beverage, among the Fante people in the Central Region of Ghana. The study aimed to document how Tuei is rooted in Fante social and ceremonial life, exploring its role as a symbol of identity, continuity, and tradition. Methods: A qualitative approach with semi-structured interviews were done with 7 participants involving one cultural expert, three elders, and three local producers. Results: The findings revealed that Tuei has a significant role in rites of passage such as marriages, funerals, and naming ceremonies, where it functions as a marker of status and social cohesion. It was daily used as a gesture of hospitality and symbol of community unity. Additionally, the study found that the nutritional benefits of Tuei was rich in essential nutrients from maize, which contribute to energy provision and digestion. Some participants also reported its traditional use in promoting digestive health and general well-being. Again, Tuei was influenced by modernization which has reduced its consumption among younger generations and elite groups. Conclusions: The study concluded with recommendations to strengthen these preservation efforts through educational initiatives, the integration of Tuei [...] Read more.
Background: Traditional foods, once carriers of cultural identity and heritage, are being quietly replaced as globalization and modern ideals redefine the choices of younger generations. This ethnographic study investigated the cultural meaning and symbolism of Tuei, an indigenous maize-based beverage, among the Fante people in the Central Region of Ghana. The study aimed to document how Tuei is rooted in Fante social and ceremonial life, exploring its role as a symbol of identity, continuity, and tradition. Methods: A qualitative approach with semi-structured interviews were done with 7 participants involving one cultural expert, three elders, and three local producers. Results: The findings revealed that Tuei has a significant role in rites of passage such as marriages, funerals, and naming ceremonies, where it functions as a marker of status and social cohesion. It was daily used as a gesture of hospitality and symbol of community unity. Additionally, the study found that the nutritional benefits of Tuei was rich in essential nutrients from maize, which contribute to energy provision and digestion. Some participants also reported its traditional use in promoting digestive health and general well-being. Again, Tuei was influenced by modernization which has reduced its consumption among younger generations and elite groups. Conclusions: The study concluded with recommendations to strengthen these preservation efforts through educational initiatives, the integration of Tuei into cultural festivals, and ongoing community engagement to ensure the continuity of this cultural practice.
Article
Open Access June 11, 2025

Biomechanical and Functional Performance of Hip Prosthesis Materials in Total Hip Arthroplasty: A Systematic Review

Abstract This systematic review aimed to evaluate the biomechanical properties, functional performance, and clinical outcomes of different hip prosthesis materials and designs used in total hip arthroplasty (THA). A comprehensive search strategy identified 34 peer-reviewed studies published between 2015 and 2024. The materials investigated included cobalt-chromium-molybdenum (CoCrMo), titanium alloys, [...] Read more.
This systematic review aimed to evaluate the biomechanical properties, functional performance, and clinical outcomes of different hip prosthesis materials and designs used in total hip arthroplasty (THA). A comprehensive search strategy identified 34 peer-reviewed studies published between 2015 and 2024. The materials investigated included cobalt-chromium-molybdenum (CoCrMo), titanium alloys, PEEK, ceramics, and advanced surface coatings such as polycrystalline diamond (PCD). In addition, dual mobility systems, lattice structures, and additively manufactured and patient-specific implants were assessed. The studies utilized clinical trials, finite element analysis, and biomechanical testing to compare outcomes such as wear resistance, stress distribution, osseointegration, and range of motion. The findings demonstrated that titanium alloys and porous lattice structures reduce stress shielding, while ceramics and CoCrMo provide superior wear resistance. Dual mobility implants improved joint stability and range of motion, particularly in high-risk patients. PEEK and PCD showed promising properties but lacked robust long-term data. The integration of advanced manufacturing technologies and material innovations has led to more personalized and biomechanically efficient solutions for THA. Further longitudinal studies are needed to validate these developments. This review provides a critical synthesis of the biomechanical, functional, and clinical implications of contemporary hip prosthetic systems.
Systematic Review
Open Access June 03, 2025

Complexity Leadership Theory Integration into Nursing Leadership and Development in Addressing COVID-19 and Future Pandemics

Abstract Complexity Leadership Theory (CLT) is a new and revolutionary concept in addressing healthcare crises worldwide. Its relevance and applications were tested during the COVID-19 pandemic. However, no definite and encompassing research was done to apply it to nursing leadership. Thus, this study examines CLT integration into nursing leadership to address the challenges posed by the pandemic. Through [...] Read more.
Complexity Leadership Theory (CLT) is a new and revolutionary concept in addressing healthcare crises worldwide. Its relevance and applications were tested during the COVID-19 pandemic. However, no definite and encompassing research was done to apply it to nursing leadership. Thus, this study examines CLT integration into nursing leadership to address the challenges posed by the pandemic. Through a systematic review of literature from PubMed, Scopus, and Web of Science, relevant studies were analyzed to determine how complexity leadership theory was defined, conceptualized, and operationalized within nursing leadership context. The findings reveal that traditional hierarchical leadership models are insufficient in a dynamic crisis environment like the pandemic. Instead, CLT’s framework which encompasses adaptive, administrative, and enabling leadership facilitates innovation, resilience, and effective interprofessional collaboration. Nurse leaders employing these strategies are better positioned to manage resources limitation, foster shared decision-making, and implement technological advancements in rapidly changing healthcare settings. Overall, this study underscores the potential of complexity leadership theory to transform nursing leadership practices by promoting continuous learning and empowerment, thereby enhancing crisis response and preparedness for future pandemics.
Systematic Review
Open Access May 20, 2025

Periprosthetic Joint Infections in Total Hip Arthroplasty: Diagnostic Advances, Treatment Algorithms, and Technological Innovations — A Comprehensive Review

Abstract Objective: This integrative review aims to critically examine the clinical management of periprosthetic joint infections (PJI) in total hip arthroplasty (THA), emphasizing decision-making strategies, diagnostic advancements, and therapeutic innovations. The study focuses on the complexity of infection control, microbial resistance, and individualized treatment planning. Methods: [...] Read more.
Objective: This integrative review aims to critically examine the clinical management of periprosthetic joint infections (PJI) in total hip arthroplasty (THA), emphasizing decision-making strategies, diagnostic advancements, and therapeutic innovations. The study focuses on the complexity of infection control, microbial resistance, and individualized treatment planning. Methods: A systematic review of the literature was conducted using PubMed, Scopus, Web of Science, and Google Scholar, targeting studies published between 2015 and 2025. Articles were selected based on their contribution to understanding the clinical, microbiological, and surgical aspects of PJI in THA. Fifty-five studies met the inclusion criteria and were analyzed descriptively. Results: PJI in THA is influenced by multifactorial risk profiles, including obesity, diabetes, and immunosuppression. Staphylococcus aureus, particularly MRSA, remains the most frequently isolated pathogen, followed by Gram-negative organisms and fungal species. Diagnostic innovations such as next-generation sequencing have enhanced pathogen detection, while two-stage revision remains the gold standard for chronic infections. Emerging strategies—such as antimicrobial coatings, tailored antibiotic protocols, and multidisciplinary care models—demonstrate promise in improving clinical outcomes. Conclusion: Managing PJI in THA necessitates a comprehensive and individualized approach, integrating early and accurate diagnosis, pathogen-specific treatment, and advanced preventive measures. The integration of emerging technologies and personalized care pathways is critical to optimizing outcomes and reducing the clinical and economic burden of PJI.
Review Article
Open Access April 10, 2025

Advancements in Pharmaceutical IT: Transforming the Industry with ERP Systems

Abstract The pharmaceutical industry is undergoing a profound transformation driven by advancements in Information Technology (IT), with Enterprise Resource Planning (ERP) systems playing a pivotal role in reshaping operations. These systems offer integrated solutions that streamline key business processes, such as production, inventory management, supply chain optimization, regulatory compliance, and data [...] Read more.
The pharmaceutical industry is undergoing a profound transformation driven by advancements in Information Technology (IT), with Enterprise Resource Planning (ERP) systems playing a pivotal role in reshaping operations. These systems offer integrated solutions that streamline key business processes, such as production, inventory management, supply chain optimization, regulatory compliance, and data integration, contributing significantly to operational efficiency and organizational agility. This paper explores the evolution and impact of ERP systems within the pharmaceutical sector, highlighting their contributions to overcoming the industry’s inherent challenges, including complex regulatory requirements, the need for accurate and real-time data, and the demand for supply chain resilience. The integration of cloud-based ERP solutions, the incorporation of emerging technologies like Artificial Intelligence (AI), Machine Learning (ML), and the Internet of Things (IoT), and enhanced data analytics capabilities have revolutionized pharmaceutical IT. These advancements not only reduce operational costs, improve forecasting accuracy, and enhance collaboration but also ensure compliance with stringent global regulations, such as Good Manufacturing Practices (GMP) and FDA guidelines. Moreover, ERP systems have been instrumental in managing the pharmaceutical supply chain, ensuring product traceability, and improving inventory control and order fulfillment processes. This manuscript examines how ERP systems enable pharmaceutical companies to maintain high standards of product quality, improve decision-making, and ensure the safety and efficacy of drugs through robust tracking and auditing mechanisms. A case study of a pharmaceutical company that implemented an ERP system demonstrates the tangible benefits, including increased operational efficiency, improved compliance rates, and enhanced customer satisfaction. However, despite the clear advantages, challenges such as customization complexities, data integration issues, and resistance to change remain. As the pharmaceutical industry continues to evolve, ERP systems will remain a cornerstone of digital transformation, facilitating smarter decision-making, better resource management, and enhanced collaboration across global operations. This paper also identifies future trends, including the potential of AI and blockchain technologies in further strengthening ERP systems and transforming the pharmaceutical landscape.
Review Article
Open Access March 29, 2025

Comprehensive Review of Conservative and Surgical Treatment Strategies for Knee Osteoarthritis: Efficacy, Safety, and Emerging Therapies

Abstract Knee osteoarthritis (KOA) is a chronic degenerative joint disorder that significantly impairs mobility and quality of life. While surgical interventions such as total knee arthroplasty (TKA) are effective in severe cases, conservative treatments are critical for early and intermediate disease management. This review evaluates the efficacy, safety, and clinical applications of both conservative and [...] Read more.
Knee osteoarthritis (KOA) is a chronic degenerative joint disorder that significantly impairs mobility and quality of life. While surgical interventions such as total knee arthroplasty (TKA) are effective in severe cases, conservative treatments are critical for early and intermediate disease management. This review evaluates the efficacy, safety, and clinical applications of both conservative and surgical treatment approaches, including lifestyle modifications, physical therapy, pharmacological interventions, regenerative medicine, and surgical procedures. The integration of a multidisciplinary approach is emphasized as a key strategy for optimizing clinical outcomes and tailoring interventions to disease severity.
Review Article
Open Access March 22, 2025

Enhancing Scalability and Performance in Analytics Data Acquisition through Spark Parallelism

Abstract Data acquisition serves as a critical component of modern data architecture, with REST API integration emerging as one of the most common approaches for sourcing external data. This study evaluates the efficiency of various methodologies for collecting data via REST APIs and benchmark their performance. It explores how leveraging the Spark distributed computing platform can optimize large scale [...] Read more.
Data acquisition serves as a critical component of modern data architecture, with REST API integration emerging as one of the most common approaches for sourcing external data. This study evaluates the efficiency of various methodologies for collecting data via REST APIs and benchmark their performance. It explores how leveraging the Spark distributed computing platform can optimize large scale REST API calls, enabling enhanced scalability and improved processing speeds to meet the demands of high volume data workflows.
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Review Article
Open Access February 26, 2025

Innovations and Challenges in Pharmaceutical Supply Chain, Serialization and Regulatory Landscape

Abstract The pharmaceutical supply chain has become increasingly complex and vulnerable to various risks, including counterfeit drugs, diversion, and fraud. As these challenges threaten patient safety and the integrity of global healthcare systems, serialization has emerged as a pivotal innovation in pharmaceutical logistics and regulatory compliance. Serialization involves assigning unique identifiers to [...] Read more.
The pharmaceutical supply chain has become increasingly complex and vulnerable to various risks, including counterfeit drugs, diversion, and fraud. As these challenges threaten patient safety and the integrity of global healthcare systems, serialization has emerged as a pivotal innovation in pharmaceutical logistics and regulatory compliance. Serialization involves assigning unique identifiers to individual drug packages, enabling precise tracking and authentication at every stage of the supply chain. This process provides unprecedented transparency, enhances product security, and facilitates real-time monitoring of pharmaceutical products as they move from manufacturers to end consumers. Despite its potential to revolutionize pharmaceutical traceability, the integration of serialization technologies faces numerous obstacles. These include high implementation costs, regulatory inconsistencies across regions, and the technological challenges of managing vast amounts of data. Moreover, the complex, multi-tiered nature of the global supply chain introduces additional risks related to data integrity, cybersecurity, and interoperability between systems. As pharmaceutical companies seek to navigate these challenges, innovations in serialization technology—such as blockchain, artificial intelligence (AI), the Internet of Things (IoT), and radio frequency identification (RFID)—are providing promising solutions to enhance efficiency, reduce fraud, and increase visibility. This manuscript explores both the innovative advancements and the key challenges associated with the integration of serialization in the pharmaceutical supply chain. It delves into the evolving regulatory landscape, highlighting the need for global harmonization of serialization standards, and examines the impact of serialization on securing pharmaceutical distribution networks. Additionally, the paper emphasizes the importance of collaboration among manufacturers, technology providers, and regulatory bodies in overcoming implementation barriers and realizing the full potential of serialization. As the pharmaceutical industry moves towards a more interconnected and data-driven future, serialization promises to play a central role in shaping the next generation of drug safety and supply chain management. By addressing the hurdles to adoption and leveraging emerging technologies, the pharmaceutical sector can create a more secure, transparent, and efficient supply chain that better serves public health and fosters greater trust among consumers and healthcare professionals alike.
Review Article
Open Access February 09, 2025

The Future of Longevity Medicine from the Lens of Digital Therapeutics

Abstract Digital therapeutics (DTx) are emerging as a pivotal tool in promoting longevity by addressing non-communicable diseases (NCDs) such as diabetes, cardiovascular diseases, and mental health disorders. These software-driven interventions offer personalized, evidence-based treatments that can be accessed via digital devices, making healthcare more accessible and scalable. One of the key advancements [...] Read more.
Digital therapeutics (DTx) are emerging as a pivotal tool in promoting longevity by addressing non-communicable diseases (NCDs) such as diabetes, cardiovascular diseases, and mental health disorders. These software-driven interventions offer personalized, evidence-based treatments that can be accessed via digital devices, making healthcare more accessible and scalable. One of the key advancements in DTx is the integration of artificial intelligence (AI) and machine learning (ML) to tailor interventions based on individual health data. This personalization enhances the effectiveness of treatments and supports preventive care by identifying risk factors early. The need for digital therapeutics is underscored by the rising prevalence of NCDs, which are responsible for a significant portion of global mortality and healthcare costs. Traditional healthcare systems often struggle to provide timely and personalized care, especially in low-resource settings. DTx can bridge this gap by offering cost-effective solutions that are easily scalable. Moreover, digital therapeutics can address health inequities by providing low-cost interventions to underserved populations, thereby reducing the burden of NCDs and improving overall health outcomes. As technology continues to evolve, the potential for DTx to enhance longevity and quality of life becomes increasingly promising. Recent advancements in longevity medicine and technology have focused on extending both lifespan and healthspan, ensuring that people not only live longer but also maintain good health throughout their extended years. This review article highlights these advancements that are contributing to this compelling subject of Longevity.
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Review Article
Open Access January 09, 2025

Advances in the Synthesis and Optimization of Pharmaceutical APIs: Trends and Techniques

Abstract The synthesis and optimization of Active Pharmaceutical Ingredients (APIs) is fundamental to pharmaceutical drug development, directly influencing drug efficacy, safety, and cost-effectiveness. Over recent years, significant advancements in synthetic methodologies and manufacturing technologies have transformed API production. This manuscript provides an overview of the latest innovations in API [...] Read more.
The synthesis and optimization of Active Pharmaceutical Ingredients (APIs) is fundamental to pharmaceutical drug development, directly influencing drug efficacy, safety, and cost-effectiveness. Over recent years, significant advancements in synthetic methodologies and manufacturing technologies have transformed API production. This manuscript provides an overview of the latest innovations in API synthesis, focusing on key techniques such as green chemistry, continuous flow chemistry, biocatalysis, and automation. Green chemistry principles, including solvent substitution and catalytic reactions, have enhanced sustainability by reducing waste and energy consumption. Continuous flow chemistry offers improved reaction control, scalability, and safety, while biocatalysis provides an eco-friendly alternative for synthesizing complex and chiral APIs. Additionally, the integration of automation and advanced process control using machine learning and real-time monitoring has optimized production efficiency and consistency. The manuscript also discusses the challenges associated with regulatory compliance and quality assurance, highlighting the role of advanced analytical techniques such as HPLC, NMR, and mass spectrometry in ensuring API purity. Looking ahead, personalized medicine and smart manufacturing technologies, including blockchain for traceability, are expected to drive further innovation in API production. This review concludes by emphasizing the need for continued advancements in sustainability, efficiency, and scalability to meet the evolving demands of the pharmaceutical industry, ultimately enabling the development of safer, more effective, and environmentally responsible medicines.
Review Article
Open Access November 16, 2024

Digital Therapeutics: A New Dimension to Diabetes Mellitus Management

Abstract Digital therapeutics (DTx) play a transformative role in diabetes management by leveraging technology to provide personalized, data-driven medical interventions. These tools enhance self-management by offering continuous monitoring and real-time feedback on glucose levels, diet, and physical activity. This personalized approach helps patients adhere to treatment plans and make informed lifestyle [...] Read more.
Digital therapeutics (DTx) play a transformative role in diabetes management by leveraging technology to provide personalized, data-driven medical interventions. These tools enhance self-management by offering continuous monitoring and real-time feedback on glucose levels, diet, and physical activity. This personalized approach helps patients adhere to treatment plans and make informed lifestyle changes, leading to improved clinical outcomes such as reduced HbA1c levels and better overall diabetes control. The importance of DTx lies in their ability to make diabetes care more accessible and convenient. Mobile apps and telemedicine platforms enable patients to receive support and guidance from anywhere, reducing the need for frequent in-person visits. Additionally, DTx often include behavioral support features like reminders, educational content, and motivational tools, which are crucial for maintaining healthy habits and managing stress. Currently, the dynamics of DTx in diabetes are rapidly evolving, with increasing integration of artificial intelligence and machine learning to further personalize and optimize care. As the adoption of these technologies grows, they hold the potential to significantly improve patient outcomes and revolutionize diabetes management on a global scale. This article will focus on the benefits of novel digital therapeutics for prevention and management of type II diabetes that are currently available in the market.
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Article
Open Access October 05, 2024

Symbolic Splendour: Integrating Adinkra Symbols in Ghana’s Most Beautiful Set Design

Abstract This study explores the integration of Adinkra symbols into the set design of Ghana’s Most Beautiful (GMB), a popular beauty pageant and reality TV show that has aired on TV3; a private television station in Ghana. GMB showcases beauty, intelligence, cultural knowledge, and traditional values, celebrating Ghana's rich cultural heritage through female contestants representing the country's diverse [...] Read more.
This study explores the integration of Adinkra symbols into the set design of Ghana’s Most Beautiful (GMB), a popular beauty pageant and reality TV show that has aired on TV3; a private television station in Ghana. GMB showcases beauty, intelligence, cultural knowledge, and traditional values, celebrating Ghana's rich cultural heritage through female contestants representing the country's diverse ethnic groups. In response to the lack of coherent Ghanaian artistic elements in previous set designs, this study employed an artistic methodology to incorporate four Adinkra symbols, Okɔdeɛ Mmɔwerɛ, Duafe, Dweninimmɛn, and Mate Masie, into the set design for the show’s eighth season. These symbols, signifying beauty, strength, wisdom, and unity respectively, were creatively integrated into a crown-like set design for the grand finale, harmonizing aesthetic trends with cultural significance. The design process was informed by rigorous research and stakeholder interviews, ensuring that the selected symbols conveyed the intended cultural messages. The results highlight the potential of traditional symbols to enhance both the cultural relevance and visual appeal of television productions. The project enriches the cultural depth of GMB production and offers a blueprint for incorporating indigenous symbols into contemporary set design. The study recommends that future productions continue exploring traditional symbols to deepen the appreciation of Ghanaian heritage and strengthen cultural identity through visual arts.
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Article
Open Access March 16, 2024

Metaverse in Nursing: A Concept Analysis

Abstract Background: Over the past decade, there has been a rapid advancement in technology and virtual reality applications, leading to the emergence of the metaverse - a virtual universe where users interact with each other and their surroundings through immersive experiences. In the nursing profession, the metaverse presents unique opportunities to enhance patient care, education, and collaboration. [...] Read more.
Background: Over the past decade, there has been a rapid advancement in technology and virtual reality applications, leading to the emergence of the metaverse - a virtual universe where users interact with each other and their surroundings through immersive experiences. In the nursing profession, the metaverse presents unique opportunities to enhance patient care, education, and collaboration. Aim: To analyze and identify the attributes of metaverse in nursing, exploring its dimensions, benefits, challenges, and implications. By examining relevant literature, this study will contribute to a better understanding of the metaverse in nursing. Method/Design: Concept analysis by Walker and Avant (2019). Results: Metaverse in nursing involves three defining attributes: use of advanced technologies, better access to education and healthcare, and collaboration and community building. Antecedents of metaverse in nursing require technological advancements, increased digital literacy, demand for innovative education, globalization of healthcare education Conclusion: Metaverse in Nursing suggests that it is a promising technology that has the potential to enhance nursing practice and improve patient outcomes, but further research is needed to fully explore the impact of its integration.
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Article
Open Access December 06, 2023

Success Factors of Adopting Cloud Enterprise Resource Planning

Abstract The technologies for cloud ERP (Enterprise Resource Planning) have revolutionized the field of information technologies. Any kind of business can benefit from their flexibility, affordability, scalability, adaptation, availability, and customizable data. An advancement of classic ERP, cloud enterprise resource planning (C-ERP) provides the benefits of cloud computing (CC), including resource [...] Read more.
The technologies for cloud ERP (Enterprise Resource Planning) have revolutionized the field of information technologies. Any kind of business can benefit from their flexibility, affordability, scalability, adaptation, availability, and customizable data. An advancement of classic ERP, cloud enterprise resource planning (C-ERP) provides the benefits of cloud computing (CC), including resource elasticity and ease of use. The rise of cloud computing affects on-premise ERP systems in terms of architecture and cost. Cloud-based ERP systems make the claim to be appropriate for digital corporate settings. System quality, security, vendor lock-in, and data accessibility are recognized as the technological issues. Industry 4.0 refers to the re-engineering and revitalization of modern factories through the integration of cloud-based operations, industrial internet connectivity, additive manufacturing, and cybersecurity platforms. One of the four main pillars of Industry 4.0, cloud-based Enterprise Resource Planning (Cloud ERP), is a component of cloud operations that aids in achieving greater standards of sustainable performance.
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Review Article
Open Access December 03, 2023

Evolution of Enterprise Applications through Emerging Technologies

Abstract The extensive globalization of services and rapid technological advancements driven by IT have heightened the competitiveness of organizations in introducing innovative products and services. Among the noteworthy innovations is enterprise resource planning (ERP). An integral field in computer science, known as artificial intelligence (AI), is undergoing a transformative integration into various [...] Read more.
The extensive globalization of services and rapid technological advancements driven by IT have heightened the competitiveness of organizations in introducing innovative products and services. Among the noteworthy innovations is enterprise resource planning (ERP). An integral field in computer science, known as artificial intelligence (AI), is undergoing a transformative integration into various industries. Grasping the concept of artificial intelligence and its application in diverse business applications is crucial, given its broad and intricate nature. The primary focus of this paper is to delve into the realm of artificial intelligence and its utilization within enterprise resource planning. The study not only explores artificial intelligence but also delves into related concepts such as machine learning, deep learning, and neural networks in greater detail. Drawing upon existing literature, this research examines various books and online resources discussing the intersection of artificial intelligence and ERP. The findings reveal that the impact of AI is evident as businesses attain heightened levels of analytical efficiency across different ERP domains, thanks to remarkable advancements in AI, machine learning, and deep learning. Artificial intelligence is extensively employed in numerous ERP areas, with a particular emphasis on customer support, predictive analysis, operational planning, and sales projections.
Review Article
Open Access July 26, 2023

Compassion Fatigue in Oncology Nurses: An Integrative Review

Abstract Oncology nurses are more likely to get compassion fatigue (CF) than nurses in other fields because of the emotional stress and poor outlook of cancer patients. Because of this, the care might not be very good, the job might not be very satisfying, and there is a good chance that the patient's pain won't be noticed. Aim. To synthesize empirical evidence on compassion fatigue in order to [...] Read more.
Oncology nurses are more likely to get compassion fatigue (CF) than nurses in other fields because of the emotional stress and poor outlook of cancer patients. Because of this, the care might not be very good, the job might not be very satisfying, and there is a good chance that the patient's pain won't be noticed. Aim. To synthesize empirical evidence on compassion fatigue in order to extract the common, central, and fundamental elements that may improve nursing care. Design. An integrative review Results. Fifteen (15) studies met the eligibility criteria wherein five themes emerged. These are the level of compassion fatigue among oncology nurses, the oncology nurses' perspectives on compassion fatigue, precipitating factors leading to CF with 2 subthemes (work environment and a feeling of lack of support), the influence of compassion fatigue on the personal lives and general well-being of cancer nurses, and the consequences on the quality of oncology nurses' professional lives at work. Conclusion. CF is a significant problem for nurses who work in specialized areas such as cancer units, demonstrated as a basic incapacity to nurture others. The integration of studies provides evidence of clinical practice application which can provide better outcomes and improve nursing care. Implications for Practice. The findings provide understanding into healthcare practice on how to avoid compassion fatigue. Clinical management approaches that can mitigate compassion fatigue and its negative repercussions are presented, as well as the formation of peer support groups that have the ability to ameliorate CF.
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Review Article
Open Access January 27, 2023

Sexual Functioning of Patients with Gynecologic Cancers: A Qualitative Synthesis

Abstract Background: Sexuality is considered to be one of the most significant markers of quality of life. This is due to the fact that sexuality is linked to ideas, feelings, behaviors, social integration, and therefore, a person's physical and mental health and well-being but with patients who have gynecologic cancers, there are significant challenges when it comes to matters of sexuality and [...] Read more.
Background: Sexuality is considered to be one of the most significant markers of quality of life. This is due to the fact that sexuality is linked to ideas, feelings, behaviors, social integration, and therefore, a person's physical and mental health and well-being but with patients who have gynecologic cancers, there are significant challenges when it comes to matters of sexuality and intimacy. Aim: To find out how gynecological cancer affects women's sexual experiences and how they express sexuality in the context of their sickness Design: A qualitative synthesis, thematic approach Result: Nineteen (19) eligible studies centered with gynecologic cancers on sexual functioning were included with two (2) main themes emerged: (1) Issues with Sexual Experiences and (2) Physical and Emotional Burden. Many individuals were found to have one or more sexual dysfunctions, which commonly caused distress. Conclusion: Changes in the women’s quality of life in the sexual aspect due to their disease takes a toll not just on the physical but in other facets as well. Better knowledge and patient-centered approaches would improve gynecologic cancer patients' capacity to cope in terms of sexual functioning. Implications: Healthcare professionals such as oncology nurses and doctors should better understand ways to address the sexual problems of their patients following the myriad of events following their diagnosis and treatment of their gynecologic cancers.
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Article
Open Access September 09, 2022

Internet addiction: A summary towards an Integration of Current Knowledge and broad Perspectives

Abstract The internet originated as a neutral device that was predominantly created to bring ease to the lives of people by making available all the information needed for the growth and prosperity of human beings, but the misuse of this communication medium has created a lot of challenges and the internet addiction is one of them. Internet addiction is a rapidly growing phenomenon exhibiting alarming [...] Read more.
The internet originated as a neutral device that was predominantly created to bring ease to the lives of people by making available all the information needed for the growth and prosperity of human beings, but the misuse of this communication medium has created a lot of challenges and the internet addiction is one of them. Internet addiction is a rapidly growing phenomenon exhibiting alarming prevalence rates and a widely recognized problematic condition around the world. Preliminary findings have shown that the unrestrained availability of this communication medium has unfetteredly increased the rate of various complications including psychological disturbances, neurological problems, and social issues. Moreover, it has accelerated the probability of those having an underlying psychological disorder being at serious risk of becoming addicted to the internet, therefore, it has stirred a hot topic of discussion among the mental health communities. The aim of this paper was to deliberately provide a brief overview of the theoretical considerations and ongoing research on internet addiction. A detailed review analysis was performed addressing the types of internet addiction, epidemiology, comorbidities associated with the excessive use of the internet, and different treatment options. Moreover, future areas of research were highlighted stressing the significance of reaching a consensus on characterizing primary features of internet addiction, and an outlook on the future goals of ongoing research has been demonstrated.
Review Article
Open Access August 27, 2022

Thermal Energy Consumption Assessment in a Fluid Milk Plant

Abstract The main energy conservation opportunities in a dairy plant are in refrigeration, and steam generation. This paper aims to identify potential energy and water savings and opportunities to improve the thermal efficiency of a fluid milk processing plant, using energy analysis and Heat Integration methods. Methodologies for energy analysis and Pinch Analysis with the use of HENSAD and Aspen Energy [...] Read more.
The main energy conservation opportunities in a dairy plant are in refrigeration, and steam generation. This paper aims to identify potential energy and water savings and opportunities to improve the thermal efficiency of a fluid milk processing plant, using energy analysis and Heat Integration methods. Methodologies for energy analysis and Pinch Analysis with the use of HENSAD and Aspen Energy Analyzer are applied. The main specific energy consumptions are defined as indicators of the progress of improved energy efficiency. The determination of energy performance indicators and energy targets of the heat exchanger network, as well as its design, allowed identifying opportunities for improvement to reduce fuel and water consumption through heat recovery in the milk pasteurization process. Current hot and cold utilities duties are satisfied, for a minimum allowable temperature difference of 20 °C. Total annual savings of 60 t of fuel oil and 15,800 m3 of water allow assessing the feasibility of an investment project for improved heat recovery.
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Article
Open Access June 20, 2022

Teachers Knowledge in Integrating Affective Domain in Teaching and Learning of Social Studies

Abstract The purpose of the study was to assess teachers’ knowledge in integrating affective domain in teaching and learning of Social Studies lessons in the junior high schools in Aowin Municipality. A quantitative approach and survey research design used the study. The study population constituted Social Studies teachers in the 40 Junior High Schools in the Aowin Municipality of the Western North Region [...] Read more.
The purpose of the study was to assess teachers’ knowledge in integrating affective domain in teaching and learning of Social Studies lessons in the junior high schools in Aowin Municipality. A quantitative approach and survey research design used the study. The study population constituted Social Studies teachers in the 40 Junior High Schools in the Aowin Municipality of the Western North Region of Ghana. Simple random and convenient sampling techniques were used to sample the respondents of the study. The sampling technique was to ensure the representativeness of the sample. The study used structured questionnaires to collect the data. Descriptive statistics in the form of percentages was used in this study. SPSS was used to analyse the data. The study concluded that the Social Studies teachers have some level of knowledge of the principles of developing affective test items. The study also indicated that Social Studies teachers in the study area can define affective objectives in behavioural terms and have some level of knowledge of the principles of developing affective test items, they do not teach the affective domain. It is recommended that, Coordinators for junior high schools and the headmasters (academic) should ensure that affective objectives are inculcated in the general lesson objectives of Social Studies teachers. Intensive in-service training should be ran for Social Studies teachers to equip them on the formulation of affective objectives. It is also recommended that in service training should be organised by the education directorate in the municipality to train teachers in the teaching of lessons involving the affective domain. The headmasters, as well as the coordinators for junior high schools, should monitor whether teacher’s qualification reflect in the teaching of the social studies lessons that involve the affective domain.
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Article
Open Access May 18, 2022

Teachers’ Technological, Pedagogical and Content Knowledge in the Junior High School Social Studies Curriculum

Abstract Knowledge of the content alone is no guarantee for effective teaching and learning, there is the need for teachers to demonstrate high level of technological and pedagogical power. The study examined the technological pedagogical content knowledge of Social Studies teachers’ in Junior High Schools in Aowin municipality in the Western North Region of Ghana. The descriptive survey design was used [...] Read more.
Knowledge of the content alone is no guarantee for effective teaching and learning, there is the need for teachers to demonstrate high level of technological and pedagogical power. The study examined the technological pedagogical content knowledge of Social Studies teachers’ in Junior High Schools in Aowin municipality in the Western North Region of Ghana. The descriptive survey design was used for the study. The population for the study included all Social Studies teachers in the public Junior High Schools in the Aowin Municipality. Simple random and purposive sampling techniques were used to select the Seventy-four (74) Junior High Schools and Seventy-four (74) the Social Studies teachers for the study. The main instrument for data collection was questionnaire. The study revealed that, teachers have adequate content knowledge to teach Social Studies but there are doubts as to whether their knowledge is current. The study also concluded that, teachers were not confident about their technological, pedagogical and content knowledge in Social Studies and this resulted in their negative attitude towards the integration of technology in classroom activities. It is recommended that, the Ghana Education Service should organize In-Service Training and refresher courses for teachers to keep them current and up-to-date their content knowledge in Social Studies. It is also recommended that, teachers should adopt positive attitudes towards learning and using technology in their day-to-day activities.
Article
Open Access February 23, 2022

Implementation of One Key Question? at an Urban Teaching Hospital: Challenges and Lessons Learned

Abstract Introduction: One Key Question® is a patient-centered tool that seeks to understand patient pregnancy intention and counseling. This pilot study aimed to assess implementation of OKQ at an urban healthcare facility and improve understanding of short interpregnancy intervals (IPI). Methods: We describe the implementation of OKQ in our setting using the Diffusion of Innovation Theory [...] Read more.
Introduction: One Key Question® is a patient-centered tool that seeks to understand patient pregnancy intention and counseling. This pilot study aimed to assess implementation of OKQ at an urban healthcare facility and improve understanding of short interpregnancy intervals (IPI). Methods: We describe the implementation of OKQ in our setting using the Diffusion of Innovation Theory as a framework. We broke this up into two phases – the first to assess provider acceptance of the OKQ integration into the clinic workflow and the second to assess how well documentation of OKQ answers occurred in our EMR. Results: Most providers in the first phase reported awareness of the inclusion of OKQ in the EHR, yet most physician providers reported only using OKQ at “some visits” (n=5) compared to the MAs, who reported using OKQ at “every visit” (n=8). Most providers felt that OKQ was an effective method of providing preconception and contraception care for women of reproductive age (n=10). Sixty-four patients completed a survey on OKQ after their visit who identified as young (mean age 28.7), either Black (46.9%) or Hispanic (51.6%) and pregnant (61%). Of those, 83% reported that they were not asked OKQ and 42% reported receiving counseling on optimal IPI. In those patients, 78% had documentation of usage of OKQ in the medical record. Discussion: The implementation of OKQ provided an opportunity to provide standardized preconception and contraception care to our patient population and improve information regarding short IPI. However, challenges existed in implementation which much be overcome to benefit from OKQ. Significance: OKQ has been used successfully in primary care and other settings to assess pregnancy intentions. This article adds to the literature by investigating the implementation of OKQ in a low-resource setting during prenatal and gynecology care. It shares struggles of implementing OKQ in an electronic medical record and how to roll out this program in a setting where pregnancy intention already is including in various forms by our providers.
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Open Access November 16, 2021

Determination of Deflection of the Vertical Components: Implications on Terrestrial Geodetic Measurement

Abstract The deflection of the vertical is an important parameter that combines both physical (astronomic) and geometric (geodetic) quantities. It is critical in such areas as datum transformation, reduction of astronomic observation to the geodetic reference surface, geoid modelling and geophysical prospecting. Although the deflection of the vertical is a physical property of the gravitational field of [...] Read more.
The deflection of the vertical is an important parameter that combines both physical (astronomic) and geometric (geodetic) quantities. It is critical in such areas as datum transformation, reduction of astronomic observation to the geodetic reference surface, geoid modelling and geophysical prospecting. Although the deflection of the vertical is a physical property of the gravitational field of the earth; which almost all terrestrial survey measurements, with the exception of spatial distances, made on the earth surface are with respect to the Earth’s gravity vector, because a spirit bubble is usually used to align survey instruments. It has been ignored in most geodetic computation and adjustment. This research work is therefore aimed at computing the component of the deflection of the vertical component for part of Rivers State using a geometric method. This method involves the integration of Global Positioning System (GPS) to obtain the geodetic coordinate of points, precisely levelling to obtain the orthometric height of this point located within the study area. By least square using MATLAB program, the estimated deflections of vertical component parameters for the test station SVG/GPS-002 were; -0.0473” and 0.0393” arc seconds for the north-south and east-west components respectively. The associated standard errors of the North-south and East-west components were ±0.0093” and ±0.0060” arc seconds, respectively. The deflection of the vertical was also computed independently from gravimetric models of the earth as: ξ = 0.0204” ±0.0008814”, η = -0.0345” ±0.0014”; ξ =0.0157” ±0.000755”, η = -0.0246” ±0.0012”; ξ = -0.0546±0.0006014, η = -0.0208±0.0006014 for EGM 2008, EGM 1996 and EGM 1984 respectively. The two-tailed hypothesis test reveals that the estimated deflection component is statistically correct at 95% confidence interval. It was observed that the effect of the deflection of the vertical is directly proportional to the distance of the geodetic baseline. Therefore, including the derived component of deflection of the vertical to the ellipsoidal model will yield high observational accuracy since an ellipsoidal model is not tenable due to its far observational error in the determination of high-quality job. It is important to include the determined deflection of the vertical component for Rivers State, Nigeria.
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Article
Open Access November 16, 2023

Innovations in Agricultural Machinery: Assessing the Impact of Advanced Technologies on Farm Efficiency

Abstract Progress in the development and adoption of technological innovations is instrumental in enhancing the efficiency of production systems across the globe. Through the introduction of cost-efficient and high-performing technologies, countries can both reduce the resource use intensity of their economies and boost the global supply of essential products. The focus of this study is to analyze the [...] Read more.
Progress in the development and adoption of technological innovations is instrumental in enhancing the efficiency of production systems across the globe. Through the introduction of cost-efficient and high-performing technologies, countries can both reduce the resource use intensity of their economies and boost the global supply of essential products. The focus of this study is to analyze the application of advanced machinery and mechanisms within the agricultural sector, a primary industry that acts as a major contributor to the gross domestic product (GDP) of many nations. Specifically, this paper provides an in-depth review of the latest impact assessments based on analytical and modeling tools conducted on agricultural machinery and production technologies. Our findings highlight the positive role played by scientific progress and innovation in driving the competitiveness, growth and improved sustainability of the agricultural sector. Over the years, advanced technologies have accelerated the development and modernization of machinery, equipment, and processes in farming. Typically, modern machinery and equipment have enabled large-scale production on farms, enhancing the cost-efficient use of both land and labor, as well as the capacity and timeliness in performing essential agricultural operations. The rapid diffusion of technical advancements has further contributed to resource savings, productivity growth, and the overall transformation of agricultural value chains. Accordingly, the implementation of appropriate enabling conditions is of vital importance in encouraging the widespread integration of technologies in agriculture, not only boosting productivity along the agri-food chain but also yielding widespread social, economic, and environmental benefits.
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Review Article
Open Access October 30, 2022

Towards Autonomous Analytics: The Evolution of Self-Service BI Platforms with Machine Learning Integration

Abstract Self-service business intelligence (BI) platforms have become essential applications for exploring, analyzing, and visualizing business data in various domains. Here, we envisage that the business intelligence platform will perform automatic and autonomous data analytics with minimal to no user interaction. We aim to offer a data-driven, intelligent, and scalable infrastructure that amplifies the [...] Read more.
Self-service business intelligence (BI) platforms have become essential applications for exploring, analyzing, and visualizing business data in various domains. Here, we envisage that the business intelligence platform will perform automatic and autonomous data analytics with minimal to no user interaction. We aim to offer a data-driven, intelligent, and scalable infrastructure that amplifies the advantages of BI systems and discovers hidden and complex insights from very large business datasets, which a business analyst can miss during manual exploratory data analysis. Towards our future vision of autonomous analytics, we propose a collective machine learning model repository with an integration layer for user-defined analytical goals within the BI platform. The proposed architecture can effectively reduce the cognitive load on users for repetitive tasks, democratizing data science expertise across data workers and facilitating a less experienced user community to develop and use advanced machine learning and statistical algorithms.
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Review Article
Open Access December 27, 2020

Enhancing Pharmaceutical Supply Chain Efficiency with Deep Learning-Driven Insights

Abstract The growing complexity of the operating environment urges pharmaceutical innovation. This essay addresses the need for the integration of advanced technologies in the pharmaceutical supply chain. It justifies the value proposition and presents a concrete use case for the integration of deep learning insights to make data-driven decisions. The supply chain has always been a priority for the [...] Read more.
The growing complexity of the operating environment urges pharmaceutical innovation. This essay addresses the need for the integration of advanced technologies in the pharmaceutical supply chain. It justifies the value proposition and presents a concrete use case for the integration of deep learning insights to make data-driven decisions. The supply chain has always been a priority for the pharmaceutical industry; research and development recognizes companies' increasing investment in big data strategies, with plans for a CAGR in big data tool adoption. The work presented herein has a preliminary explorative character to recuperate and integrate evidence from partly overlooked practical experience and know-how. The practical relevance of the essay is directed toward practitioners in pharmaceutical production, supply chain management, logistics, and regulatory agencies. The literature has shown a long-term concern for enhanced performance in the pharmaceutical supply chain network. This essay demonstrates the application of deep learning-driven insights to reveal non-evident flow dependencies. The main aim is to present a comprehensive insight into deep learning-driven decision support. The supply chain is portrayed in a holistic manner, seeking end-to-end visibility. Implications for public policy are discussed, such as data equity: many countries are protecting their populations and economic growth by building resilience and efficiency to ensure the capacity to move goods across supply chains. The implementation strategy is covered. The combined reduction of variability, efficiency as matured richness, reliability (on stochastic flows and their understanding through deep learning and data), and system noise (increased dampening through the inclusiveness of all stakeholders) results in increased responsiveness of supply chains for pharmaceutical products. Future work involves the integration of external data, closing the loop between planning and its application in reality.
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Open Access December 27, 2022

Advancing Pain Medicine with AI and Neural Networks: Predictive Analytics and Personalized Treatment Plans for Chronic and Acute Pain Managements

Abstract There is a growing body of evidence that the number of individuals suffering from chronic and acute pain is under-reported and the burden of the veteran, aging, athletic, and working populations is rising. Current pain management is limited by our capacity to collaborate with individuals continuing normal daily functions and self-administration of pain treatments outside of traditional healthcare [...] Read more.
There is a growing body of evidence that the number of individuals suffering from chronic and acute pain is under-reported and the burden of the veteran, aging, athletic, and working populations is rising. Current pain management is limited by our capacity to collaborate with individuals continuing normal daily functions and self-administration of pain treatments outside of traditional healthcare appointments and hospital settings. In this review, the current gap in clinical care for real-time feedback and guidance with pain management decision-making for chronic and post-operative pain treatment is defined. We examine the recent and future applications for predictive analytics of opioid use after surgery and implementing real-time neural networks for personalized pain management goal setting for particular individuals on the path to discharge to normal function. Integration of personalized neural networks with longitudinal data may enable the development of future treatment personalizations paired with electrical simulations.
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Review Article
Open Access December 27, 2023

Leveraging Artificial Intelligence to Enhance Supply Chain Resilience: A Study of Predictive Analytics and Risk Mitigation Strategies

Abstract The management of supply chains is increasingly complex. This study provides a comparative analysis of the cost-benefit analysis for managing various risks. It identifies the financial implications of leveraging artificial intelligence in supply chains to better address risk. Empirical results show a business case for managing some sources of risk more proactively facilitated through predictive [...] Read more.
The management of supply chains is increasingly complex. This study provides a comparative analysis of the cost-benefit analysis for managing various risks. It identifies the financial implications of leveraging artificial intelligence in supply chains to better address risk. Empirical results show a business case for managing some sources of risk more proactively facilitated through predictive modeling techniques offered by AI. Across investigation streams, the use of AI results in an average total cost saving ranging from 41,254 to 4,099,617. Findings from our research can be used to inform managers and theorists about the implications of integrating AI technologies to manage risks in the supply chain. Our work also highlights areas for future research. Given the growing interest in studying sub-second forecasting, our research could be a point of departure for future investigations aimed at considering the impact of forecasting horizons such as an intra-day basis. We formulate a conceptual framework that considers how and to what extent performance evaluation metrics vary according to differences in the fidelity of predictive models and factor importance for identifying risks. We also utilize a mixed-method approach to demonstrate the applicability of our ideas in practice. Our results illustrate the financial implications of integrating AI predictive tools with business processes. Results suggest that real-world companies can circumvent inefficiencies associated with trying to manage many classes of risk via the use of AI-enhanced predictive analytics. As managers need to justify investment to top management, our work supports decision-making by providing a means of conducting a trade-off analysis at the tactical level.
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Review Article
Open Access July 16, 2023

Pharmaceutical Supply Chain Distribution: Mitigating the Risk of Counterfeit Drugs

Abstract The global pharmaceutical supply chain plays a crucial role in ensuring the timely and safe delivery of medicines to patients worldwide. However, the increasing presence of counterfeit drugs within this supply chain poses a significant and growing risk to public health, patient safety, and the integrity of the pharmaceutical industry. Counterfeit drugs—medications that are fraudulently [...] Read more.
The global pharmaceutical supply chain plays a crucial role in ensuring the timely and safe delivery of medicines to patients worldwide. However, the increasing presence of counterfeit drugs within this supply chain poses a significant and growing risk to public health, patient safety, and the integrity of the pharmaceutical industry. Counterfeit drugs—medications that are fraudulently manufactured, mislabeled, or contain incorrect or harmful ingredients—are a major concern as they can lead to ineffective treatments, adverse health effects, and even death. Despite stringent regulatory frameworks and advanced technological solutions, counterfeit drugs continue to infiltrate legitimate supply chains due to factors such as the complexity of the distribution system, global trade practices, and inadequate enforcement in certain regions. This manuscript explores the primary causes behind the proliferation of counterfeit drugs in pharmaceutical distribution, the associated risks, and the multifaceted approaches required to address this growing threat. It discusses the importance of regulatory measures, including international cooperation and stronger compliance frameworks, as well as the role of emerging technologies like serialization, blockchain, and RFID in ensuring traceability and product authenticity. By focusing on the integration of these technologies, the paper also highlights the potential of innovative solutions to enhance transparency, reduce vulnerabilities, and protect the integrity of pharmaceutical supply chains. Additionally, it emphasizes the importance of public awareness campaigns and collaboration between key stakeholders, including pharmaceutical manufacturers, distributors, regulators, and healthcare providers, in creating a more secure and trustworthy pharmaceutical distribution ecosystem. Through a comprehensive exploration of these strategies, this manuscript aims to provide a roadmap for mitigating the risks posed by counterfeit drugs and ensuring the safety and efficacy of medicines for consumers worldwide.
Review Article
Open Access December 27, 2023

Leveraging Machine Learning Techniques for Predictive Analysis in Merger and Acquisition (M&A)

Abstract M&A is a strategic concept of business growth through consolidation, gaining market access, increasing strategic positions, and increasing operational efficiency. To understand the dynamics of M&A, this paper looks at aspects such as targeted firm identification, evaluation, bidding for the target firm, and post-acquisition integration. All forms of M&A, including horizontal, [...] Read more.
M&A is a strategic concept of business growth through consolidation, gaining market access, increasing strategic positions, and increasing operational efficiency. To understand the dynamics of M&A, this paper looks at aspects such as targeted firm identification, evaluation, bidding for the target firm, and post-acquisition integration. All forms of M&A, including horizontal, vertical, conglomerate, and acquisitions, are discussed in terms of goals and values, including synergy, cost reduction, competitive advantages, and access to better technology. However, issues such as cultural assimilation, adhesion to regulations, and calculating an inaccurate value are also resolved. The paper then goes deeper to provide insight into how predictive analytics applies to M&A, using ML to improve decision-making with forecasting benefits. Including healthcare, education, and construction industries, the presented predictive models using regression analysis, neural networks, and ensemble techniques help to make decisions. Through time series and real-time data, PDA enables sound M&A strategies, effective risk management and smooth integration.
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Open Access December 27, 2023

Understanding the Fundamentals of Digital Transformation in Financial Services: Drivers and Strategic Insights

Abstract The current financial services sector is realising considerable changes in its operations due to development in technology and embracing of digital platforms. This evolution is changing the established concepts of business, consumers and channels of delivery of services. Financial services firms are changing the way they work through digital transformation due to developments in technology, [...] Read more.
The current financial services sector is realising considerable changes in its operations due to development in technology and embracing of digital platforms. This evolution is changing the established concepts of business, consumers and channels of delivery of services. Financial services firms are changing the way they work through digital transformation due to developments in technology, changes in customer needs, and an increase in emphasis on sustainability. Understanding the opportunities, risks, and new trends in digital transformation is the focus of this paper. Opportunities include efficient real-time decision-making processes, increased transparency and better process controls, which are balanced by the threats of change management, dubious organization-technology fit, and high implementation costs. The study also examines recent advancements, including the application of machine learning and artificial intelligence, developments in mobile and online banking, integration of blockchain, and increasing focus on security and personalised banking. A literature review yields some findings from different studies on rural financial services, the evolution of the blockchain, drivers of digital transformation, cloud-based learning approaches, and emerging sustainability practices. All of these results suggest that more strategic planning, analytics, and more focus on ensuring that organisational objectives are met with transformations should be pursued. Hence, this research findings add to the existing literature in determining how innovative and digital technologies are likely to transform the financial services sector and advance sustainability.
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Open Access December 27, 2019

Revolutionizing Patient Care and Digital Infrastructure: Integrating Cloud Computing and Advanced Data Engineering for Industry Innovation

Abstract This work details how the integration of cloud computing and advanced data engineering can innovate and reshape patient care and digital infrastructure. In the healthcare sector, cloud services offer the necessary support to generate digitally-oriented services and service kits. These services can contain high levels of availability, low levels of latency, and on-demand scaling capabilities, while [...] Read more.
This work details how the integration of cloud computing and advanced data engineering can innovate and reshape patient care and digital infrastructure. In the healthcare sector, cloud services offer the necessary support to generate digitally-oriented services and service kits. These services can contain high levels of availability, low levels of latency, and on-demand scaling capabilities, while following the strictest data protection laws and regulations. On the other hand, these services can be combined with data engineering techniques to construct an ecosystem that enhances and adds an optimized data layer on any cloud environment. This ecosystem includes technologies to acquire, process, and manage healthcare data while respecting all regulatory obligations and institutions and can be part of a comprehensive digitalization strategy. The objective is to augment the healthcare services that the industry offers by leveraging healthcare data and AI technologies. Designed services, processes, and technologies can be described either as industry-agnostic services or healthcare-specific services that process and manage electronic healthcare records (EHR). Industry-agnostic services offer a set of tools and methodologies to conduct optimized data experiments. The goal is to exploit any variety, velocity, volume, and veracity of medical data. Healthcare-specific services offer a set of tools and methodologies to connect to any common EHR vendor in a privacy-preserving manner. Participating companies are thus able to hold, share, and make use of healthcare data in real-time. The proposed architecture can be transformative for the healthcare industry, opening up and facilitating experimentation on new and scalable service models. The transition to a more digital health approach would help overcome the limits encountered in traditional settings. Limitations in the availability of healthcare facilities and healthcare professionals have underpinned the increasing share of telemedicine in the care process. However, the record-keeping of the patients that undergo care outside of traditional healthcare facilities is often missing and can severely influence the continuity of treatment. Identifying new methods to implement disease prevention and early intervention processes is crucial to avoid more extensive treatment and to support those on multiple line therapies. For chronic patients, having a service available that monitors the state of health and intervenes when parameters go off the wanted range is crucial. However, the same patients are the most under the influence of the decision of care providers; a second opinion might be given remotely which the patient can access at any time on-demand. To address these different kinds of services, an ecosystem composed of a dictionary's worth data layer is outlined, able to live and operate seamlessly in any cloud environment. This future work's envisioned outcome is the rapid evolution and re-definition of the European healthcare landscape.
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Review Article
Open Access December 27, 2019

Data Engineering Frameworks for Optimizing Community Health Surveillance Systems

Abstract A Changing World Demands Optimized Health Surveillance Systems – and How Data Engineering Can Help There is a growing urgency to manage the public health and emergency response practices effectively today, in light of complex and emerging health threats. Fortunately, a host of new tools, including big and streaming data sources, methods such as machine learning, new types of hardware like [...] Read more.
A Changing World Demands Optimized Health Surveillance Systems – and How Data Engineering Can Help There is a growing urgency to manage the public health and emergency response practices effectively today, in light of complex and emerging health threats. Fortunately, a host of new tools, including big and streaming data sources, methods such as machine learning, new types of hardware like blockchain or secure enclaves, and means of data storage and retrieval, have emerged. But, with these innovations comes a grand challenge: how to blend with, and adapt them to, the traditional public health practices. The long-in-place infrastructures and protocols to protect and ensure the welfare of communities are in need of change, or at least update, to enhance their marked longevity of impact directly on the health outcomes and community wellbeing they were designed to fortify. It is in this vein that the essay is written and composed. The investigation in this essay is to query what, particularly, might be the aspects and influences of the emerging veritable cornucopia of new data engineering frameworks that are either being developed specifically for health surveillance and wellness, or are available to be co opted from devices and services already thriving in the current market and research milieu. Knowing what these ways may be could well aid in molding their uptake and spread, ensuring their beneficial impacts on those communities who stand to gain the most. The essay is divided into several key segments. After this introduction, section two details the research methods. In the section that follows, the maximum health outcome potentials of these novel frameworks are reviewed. Part four of the essay takes a more critical approach, addressing how the success of these methods may be hindered and future research avenues. Lastly, the concluding information suggests some actions to take to aid best suit the implementation of these ways, and suggests some thoughts for further research after the completion of these inquiriestrand [1].
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Case Report
Open Access December 27, 2022

Advanced Optical Proximity Correction (OPC) Techniques in Computational Lithography: Addressing the Challenges of Pattern Fidelity and Edge Placement Error

Abstract The complexity of manufacturing photolithography has increased significantly. The increase in the level of integration has driven smaller feature-sized integrated circuits (ICs). The evolution in stepper technologies has been geometric. This has enabled the printing of printed ICs with a 45 nm feature size. Improvement in lithographic technology is moving towards 32 nm. This feature-size roadmap [...] Read more.
The complexity of manufacturing photolithography has increased significantly. The increase in the level of integration has driven smaller feature-sized integrated circuits (ICs). The evolution in stepper technologies has been geometric. This has enabled the printing of printed ICs with a 45 nm feature size. Improvement in lithographic technology is moving towards 32 nm. This feature-size roadmap poses many challenges to semiconductor manufacturing technology. Advanced photomask synthesis, high-NA steppers, and computational lithography are some examples of the solution space. Optical proximity correction (OPC) and model-based optical proximity correction (MBOPC) are subsets of this solution space. OPC has matured significantly and is the de facto solution for manufacturing photomasks up to the 65 nm node. The OPC technique has been further refined as model-based OPC and has been applied to advanced printing technology of 45 nm. The OPC solution for 45 nm technology has limitations of mask rule check (MRC) and manufacturability restrictions. These restrictions are inevitable in OPC and MBOPC solutions because of the limits in lithographic technology. The technology evolution towards 32 nm has equally challenged the non-linear treatment of wafer-level problems in OPC solutions. PBOPC has limitations in reducing the wafer optical proximity error of the granny's issue, edge placement, mask rule check, etc. PBOPC also has limitations in reducing the mask error enhancement factor. With all these challenges, it is still a formidable solution methodology to address the wafer and mask level issues. Such a formidable solution architecture can result in a limited number of PBOPC solutions. This text looks at the performance of advanced PBOPC features on exposure tuning and the effects of higher-order wafer and aerial image effects. This text also discusses the performance of continuous process correction of masks, lenses, and scanners.
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Case Report
Open Access December 27, 2021

Advancements in Smart Medical and Industrial Devices: Enhancing Efficiency and Connectivity with High-Speed Telecom Networks

Abstract Emerging smart medical instruments combined with advanced smart industrial equipment facilitate the collection of vast volumes of critical data. This data not only enables significantly more accurate and cost-effective diagnosis and maintenance but also enriches the datasets available for AI algorithms, leading to improved insights and outcomes. The integration of high-speed and ultra-reliable [...] Read more.
Emerging smart medical instruments combined with advanced smart industrial equipment facilitate the collection of vast volumes of critical data. This data not only enables significantly more accurate and cost-effective diagnosis and maintenance but also enriches the datasets available for AI algorithms, leading to improved insights and outcomes. The integration of high-speed and ultra-reliable telecommunications infrastructure is crucial, as it supports the cloud model. This model allows for off-device aggregation in the cloud, which effectively offloads infrastructure demands and provides an extended runway for future technological improvements before the deployment of the next generation of devices. However, in certain scenarios, latency and bandwidth limitations present significant challenges. These limitations require that a substantial amount of AI and machine learning processing is conducted directly on the transmitted data, which places rigorous demands on both the processing subsystems and the communications links themselves. The current project directly addresses the accelerator side of this multifaceted issue. It will carry out comprehensive end-to-end demonstrations leveraging pilot 5G networks and telemedicine facilities, collaborating closely with major industry participants to showcase the capabilities and potential of this innovative technology. This collaborative effort is essential to pushing the boundaries of what is possible in smart medical instruments and industrial applications [1].
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Open Access December 27, 2021

Advanced Computational Technologies in Vehicle Production, Digital Connectivity, and Sustainable Transportation: Innovations in Intelligent Systems, Eco-Friendly Manufacturing, and Financial Optimization

Abstract This paper includes the impacts of the Internet of Things (IoT), Big Data, and other emerging technologies in the vehicle production sector, digital connectivity, and sustainable transport system. Automated and intelligent transportation for safe, efficient, and sustainable transport systems will be stressed. Key factors to promote automated or connected vehicles including connected environment, [...] Read more.
This paper includes the impacts of the Internet of Things (IoT), Big Data, and other emerging technologies in the vehicle production sector, digital connectivity, and sustainable transport system. Automated and intelligent transportation for safe, efficient, and sustainable transport systems will be stressed. Key factors to promote automated or connected vehicles including connected environment, integration of all transport modes, advanced cooperative systems, and policy enforcement will be discussed. This paper contains the Axiomatic Categorisation Framework (AFS) for the dynamic alignment in a collection of disparate functions in cyber-physical systems (CPS). Developed system is enhanced for breaking the rules within autonomous vehicles (AV). It means the human personal injury is inevitable while the vehicle does not do any rules. Especially in complicated traffic situations, many of the constraints are mutually exclusive, and there is no way to obey all of them at a time. Also, there is no way to ensure that the self-driving vehicle has priority in all situations [1]. Public distrust in AV systems has to be increased and the investment in this technology has to slow down. Instead, a human driver should be partially responsible for operation. The development of a driver-behavior assistant (DBA) system is proposed, which should be able to break the rules for the distances of such slow development. It is intended to be effective in non-deterministic situations while maintaining the safety of the AV and those involved in the event. A driver's actions would not only be acceptable as a driving strategy but also would be predictable, and therefore other road users could unambiguously react.
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Open Access December 27, 2022

Integrating generative AI into financial reporting systems for automated insights and decision support

Abstract Generative AI refers to deep learning technology that can automatically produce original text, images, audio, video, and other outputs. With its emerging capabilities, Generative AI can radically change the dynamics of key operational processes in most industries. In this document, we illustrate how it is possible to integrate Generative AI technologies into the Financial Reporting System (FRS) of [...] Read more.
Generative AI refers to deep learning technology that can automatically produce original text, images, audio, video, and other outputs. With its emerging capabilities, Generative AI can radically change the dynamics of key operational processes in most industries. In this document, we illustrate how it is possible to integrate Generative AI technologies into the Financial Reporting System (FRS) of a corporation. The integration will allow the FRS to deliver on demand concise and lucid insights to its associated users on what is happening in the corporation and different aspects of the corporation performance assessment, such as its liquidity, solvency, profitability, organizational structure, and share buy back decision. The integration will also facilitate the delivery of what-if analyses associated with different strategic and tactical decisions taken by the corporation management, such as capital budgeting and profit distribution decisions. The unique added value of several attributes of these insightful analytics is automating the responses to ongoing requests of the FRS users on the corporation. Generative AI capabilities are rapidly expanding. The integration can be applied not only for the corporate FRS but any FRS at the national or global levels delivered by a central bank or an accounting standards setter. Any of these FRS can be made into a unique “hub” for the integrated Generative AI technologies. An equally innovative possible generalized integration could put any corporate process at the center and its supporting FRS tasks and deliverables in its periphery.
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Open Access December 27, 2019

Transforming the Retail Landscape: Srinivas’s Vision for Integrating Advanced Technologies in Supply Chain Efficiency and Customer Experience

Abstract Technological advances have had a transformative impact on the retail landscape. Challenges arise with guaranteeing technological changes lead to, rather than detract from, increased efficiency and positive experiences. First, integrating technology into the supply chain in an aggressive way is costly. It requires vast changes to existing systems and developments of cross-industry communication [...] Read more.
Technological advances have had a transformative impact on the retail landscape. Challenges arise with guaranteeing technological changes lead to, rather than detract from, increased efficiency and positive experiences. First, integrating technology into the supply chain in an aggressive way is costly. It requires vast changes to existing systems and developments of cross-industry communication protocols. Secondly, the public is often quick to reject technological changes or slow to become users. Finally, ensuring that technological advancements do not only benefit the top few retailers and are accessible to those of any size poses a challenge, as has been seen in the fate of only a handful of radical changes in retail technology. On the other hand, an integral aspect of technology, particularly that used for big data collection and processing, is that it can account for these and other variables. It can predict the success of ventures into modernizing or developing new systems and can identify more effective and efficient ways to do so. Of course, the concerns of job loss or technological monopoly still loom. But, it would seem, the continued advancement of technology in the retail landscape is inevitable.
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Open Access December 27, 2020

Optimizing Unclaimed Property Management through Cloud-Enabled AI and Integrated IT Infrastructures

Abstract With unclaimed property assets reaching record levels, businesses have become, in some cases, overwhelmed and hamstrung by stagnant, unoptimized processes. That sentiment is compounded by ever-evolving regulatory changes, resulting in organizations struggling to hit compliance deadlines while delivering an optimal claimant experience. Often, early systems had periods of short-term success but are [...] Read more.
With unclaimed property assets reaching record levels, businesses have become, in some cases, overwhelmed and hamstrung by stagnant, unoptimized processes. That sentiment is compounded by ever-evolving regulatory changes, resulting in organizations struggling to hit compliance deadlines while delivering an optimal claimant experience. Often, early systems had periods of short-term success but are on the verge of obsolescence, resulting in stressed workflows and cumbersome integrations. Deploying an integrated IT infrastructure, supported by cloud-enabled AI, represents the quickest path to modernizing unclaimed property management. A fully integrated IT infrastructure is crucial to optimize the management of unclaimed property [1]. When lone solutions exist across an organization, companies miss out on automation opportunities generated through the interconnectedness of systems and data. AI presents organizations with the opportunity to traverse these gaps, enabling a vast library of applications to improve the perturbed workflows of unclaimed property teams. Automated data extraction, document comparison, fraudulent claim detection, and workflow completion analysis are just a few popular applications well suited for the unclaimed property space. In addition to the lagging technology currently deployed by many organizations, the unclaimed property landscape itself is evolving. Compliance issuance, asset availability, rates, the ability to collect fraudulently posted claims, and the claimant experience have all become hot-button items that are now front of mind for regulation agencies and businesses alike. Issuing duplication letters in a compliant manner, accommodating claimant inquiries regarding held assets, and managing, processing, and understanding the operational impact of rate changes are vexing problems many organizations now find themselves playing catch-up to address. The opportunity posed by cloud-enabled AI is furthered by economic, regulatory, and report cycle pressures on unclaimed property teams to do more with the same size or fewer resources. It’s now no longer simply a case of hitting the audit date deadline and checking off a box but an emerging priority for businesses at all sides of the market, from Fortune 500 to mid-market firms. In-house shared service teams are comfortable in areas of monitoring and curating business data; however, unclaimed property is an unknown territory with a learning curve, compliance gaps, and operational holes that, if ignored, stand to scale up exponentially. The combined fallout from regulatory changes and the recent pandemic have only made the situation riskier, with increased volatility in balancing time-sensitive tasks against stringent regulatory deadlines and growing claimant outreach.
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Open Access December 29, 2020

Enhancing Government Fiscal Impact Analysis with Integrated Big Data and Cloud-Based Analytics Platforms

Abstract While several application domains are exploiting the added-value of analytics over various datasets to obtain actionable insights and drive decision making, the public policy management domain has not yet taken advantage of the full potential of the aforementioned analytics and data models. To this end, in this paper authors present an overall architecture of a cloud-based environment that [...] Read more.
While several application domains are exploiting the added-value of analytics over various datasets to obtain actionable insights and drive decision making, the public policy management domain has not yet taken advantage of the full potential of the aforementioned analytics and data models. To this end, in this paper authors present an overall architecture of a cloud-based environment that facilitates data retrieval and analytics, as well as policy modelling, creation and optimization. The environment enables data collection from heterogeneous sources, linking and aggregation, complemented with data cleaning and interoperability techniques. An innovative approach for analytics as a service is introduced and linked with a policy development toolkit, which is an integrated web-based environment to fulfil the requirements of the public policy ecosystem stakeholders [1]. Large information databases on various public issues exist, but their usage for public policy formulation and impact analysis has been limited so far, as no cloud-based service ecosystem exists to facilitate their efficient exploitation. With the increasing availability and importance of both public big and traditional data, the need to extract, link and utilize such information efficiently has arisen. Current data-driven web technologies and models are not aligned with the needs of this domain, and therefore, potential candidates for big data, cloud-based and service-oriented public policy analysis solutions should be investigated, piloted and demonstrated [2]. This paper presents the conceptual architecture of such an ecosystem based on the capabilities of state-of-the-art cloud and web technologies, as well as the requirements of its users.
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Open Access December 27, 2020

Building Foundational Data Products for Financial Services: A MDM-Based Approach to Customer, and Product Data Integration

Abstract Imagine a consumer financial services company with 20 million customers. Its sales and marketing organizations collaborate across product lines, deploying hundreds of marketing campaigns each quarter that aim to increase customer product usage and/or cross-buying of products. Each campaign is based on forecasts of customer responses derived from predictive models updated every quarter. The goals [...] Read more.
Imagine a consumer financial services company with 20 million customers. Its sales and marketing organizations collaborate across product lines, deploying hundreds of marketing campaigns each quarter that aim to increase customer product usage and/or cross-buying of products. Each campaign is based on forecasts of customer responses derived from predictive models updated every quarter. The goals of these models are to achieve large return on investment ratios and to maximize contribution to local profit centers. What’s important is that their modeling is based only on data created, curated and maintained by these marketing organizations. The difference today is that the modeling is no longer based solely on a small number of response-determined variables that are constantly assessed in terms of importance. A quarterly campaign update generates hundreds of statistical models — involving campaign responses, purchase-lag time, the relative magnitude of the direct effect, and the cross-buying effects — using thousands of variables, including customer demographics, life stage, product transactions, household composition, and customer service history. It’s a network of models, not just a table of variable-by-residual importance values. But that’s only part of the story of data products. The predictive modeling utilized by these campaign plans is based on analytics and data preparation, which are data products in their most diminutive form. These products would be even more elementary were they not crafted quarterly by highly skilled, experienced modelers using advanced software and processes. Most companies have enough data to create models that contain not simply hundreds of variables, but thousands, so that the focus can return to information instead of data reduction. These models largely replace the internal econometric models previously used to produce advanced forecasts in the absence of campaign modeling. People used these forecasts to simulate ROI and contribution forecasts for the planned campaigns. In the old days, reliance on econometrically forecast ROI-guideline contribution values reduced the reliance on the marketing campaign modelers because of a lack of trust in their predictive ability.
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Open Access December 18, 2020

Intelligent Supply Chain Ecosystems: Cloud-Native Architectures and Big Data Integration in Retail and Manufacturing Operations

Abstract The supply chain ecosystem plays a very important role in the success or failure of organizations, markets, and economies. Supply chain ecosystems are broadly defined as supply chain organizations and their collaborators. Today's combined challenges of pandemic shutdowns, rising internet usage, and skyrocketing climate change concerns demand that the supply chain ecosystem better connect with [...] Read more.
The supply chain ecosystem plays a very important role in the success or failure of organizations, markets, and economies. Supply chain ecosystems are broadly defined as supply chain organizations and their collaborators. Today's combined challenges of pandemic shutdowns, rising internet usage, and skyrocketing climate change concerns demand that the supply chain ecosystem better connect with customers, when and how they want, to provide products and services with high levels of availability and zero defects, yet collaboratively do this to reduce transportation and production risks, often at the same time reducing operational costs and carbon footprints. Addressing these challenges, this work explores the cloud delivery capabilities of cloud-native architectures to enable the big data integrations and analytics that are needed to grow smarter supply chain ecosystems. This work describes what smart supply chain ecosystems are and how they are planning to grow their technology and integration capabilities. Discussing the industry-leading advanced and manufacturing technology producer ecosystems, it is explained how their technology collaboration and investment plans are driven by climate change and job creation goals. With these background models, the work examines the new digital reality of customer-driven experiences and economies that are demanding cloud-native and intelligent technology partnerships to deliver climate objectives, operational responsiveness, and compatibility to avoid trading economies of scale for economies of integration. The final objectives of this paper are to share key ideas about the need to balance the growing customer service direct-to-consumer business models with those for collaborative investment by market and industry. In doing this, it hopes to promote an intelligent supply chain ecosystem foundation for helping its different participating countries survive and thrive in the digital economy.
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Open Access December 24, 2022

Web-Centric Cloud Framework for Real-Time Monitoring and Risk Prediction in Clinical Trials Using Machine Learning

Abstract Advances in web-centric cloud computing have facilitated the establishment of an integrated cloud environment connecting a wide variety of clinical trial stakeholders. A web-centric cloud framework is proposed for real-time monitoring and risk prediction during clinical trials. The framework focuses on identifying relevant datasets, developing a data-management interface, and implementing [...] Read more.
Advances in web-centric cloud computing have facilitated the establishment of an integrated cloud environment connecting a wide variety of clinical trial stakeholders. A web-centric cloud framework is proposed for real-time monitoring and risk prediction during clinical trials. The framework focuses on identifying relevant datasets, developing a data-management interface, and implementing machine-learning algorithms for data analysis. Detailed descriptions of the data-management interface and the machine-learning processes are provided, targeting active clinical trials with therapeutic uses in cancer. Demonstrations utilize publicly available clinical-trial data from the ClinicalTrials.gov repository. The real-time monitoring and risk prediction systems were assessed by developing five supervised-classification-machine-learning models for trial-status prediction and six unsupervised models for patient-safety-profile assessment, each representing a different phase of the clinical-trial process. All supervised models yielded high accuracy and area-under-the-curve values at the testing stage, while the unsupervised models demonstrated practical applicability. The results underscore the advantages of using the trial-status algorithm, the patient-safety-profile model, and the proposed framework for performing real-time monitoring and risk prediction of clinical trials.
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Open Access December 24, 2022

Cloud Native ETL Pipelines for Real Time Claims Processing in Large Scale Insurers

Abstract Cloud native ETL pipelines support the extract and transform phases of real time claims processing in large scale insurers. The cloud native approach offers dramatic improvements in scalability, reliability, resiliency and agility as well as seamless integration with the diverse set of data sources, destinations and technologies characteristic of large scale insurers. The ETL process extracts data [...] Read more.
Cloud native ETL pipelines support the extract and transform phases of real time claims processing in large scale insurers. The cloud native approach offers dramatic improvements in scalability, reliability, resiliency and agility as well as seamless integration with the diverse set of data sources, destinations and technologies characteristic of large scale insurers. The ETL process extracts data from source systems such as core transaction, fraud, customer and accounting processes, transforms the data to create a usable format for analytics and other applications, and loads the resulting tables into business intelligence or data lake systems for subsequent storage and analysis. By addressing these two phases of the overall ETL process, cloud native ETL pipelines can provide timely, reliable and consistent data to data scientists, actuaries, underwriters and other analysts. Real time processing represents a key priority within the overall claims process: faster, more accurate claim approvals reduce insurer costs, improve customer service and enhance premium pricing. As a result, a variety of claims related use cases are moving from batch to real time.
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