A phytosociological review is carried out of the pine forest formations on the islands of Cuba and Hispaniola (Caribbean), due to the diversity of soils and environments. We collected 10 plant associations belonging to the class Byrsonimo-Pinetea caribaea growing on siliceous, calcareous and sandy substrates and 21 associations on special, serpentine and ophite substrates and on ultramafic rocks belonging to the class Caseario crassinervis-Pinetea cubensis, exclusive to Cuba; while the association of pine forests on serpentines in Hispaniola is included in the class Phyllantho orbicularis-Neobracetea valenzuelanae with a Caribbean distribution. The comparative phytosociological and statistical study reveals phytosociological anomalies in the inclusion of various syntaxa, and in the description of other syntaxa according to the International Code of Phytosociological Nomenclature (ICPN). We therefore propose a change in status for several of the subassociations described: subass. ilicetosum repandae: syn. var. con Ilex repanda; subass. schmidtottietosum shaferi: syn. var. with Schmidtottia shaferi; subass. acrosynanthetosum trachyphylli: syn. var. with Acrosynanthus trachyphyllus; subass. psychotrietosum grandis: var. con Psychotria grandis; subass. notodonetosum roigii: syn. var. with Notodon roigii. We also propose a nomen novum: jaquinietosum oxhyphyllae Reyes & Acosta 2012 ex Cano et al. hoc loco.

The purpose of this study was to assess safety conditions of learners in Kindergarten schools in Komenda Edina Eguafo Abirem (K.E.E.A) Municipality in the Central Region of Ghana. The qualitative research approach and the Instrumental Case Study Design were adopted for the study. The population of the study comprised public kindergarten teachers and schools in Komenda Edina Eguafo Abirem municipality in the Central Region of Ghana. Convenient and purposive sampling techniques were used to select sixteen (16) public kindergarten teachers and eight (8) kindergarten schools for the study. The semi-structured interview and observation checklist were the instruments utilized in the data collection for this study. The data were analysed and interpreted thematically using online qualitative software, Taguette version 1.3. The study indicated that, most kindergarten school buildings in the KEEA municipality pose threats to both learners and teachers as result of over-aged or poorly constructed buildings and isolated and bushy environment which attracts animals like lizards, wall geckos and poisonous snakes and psychological and emotional threat to both teachers and learners. It is recommended that, the Ministry of Education in collaboration with the Ghana Education Service should set up a School Supervision for Safety Department (SSSD) to control and oversee safety issues in the kindergarten schools in Ghana. The School Supervision for Safety Department should create awareness advocacy for school safety so that school safety becomes a nationwide concern. It is also recommended that, the School Supervision for Safety Department must liaise with other stakeholders to enforce frequent assessment of school buildings, infrastructure and materials for safety.

Knowledge about the glycaemic load of a food is very important in minimizing the prevalence of diabetes and other Non-Communicable Diseases. The purpose of this study was to determine the glycaemic load of the different varieties of fufu in the Wenchi municipality in Ghana. Quantitatively, the study adopted a crossover experimental research design. The research was carried out in Wenchi, the capital of the Wenchi Municipal Assembly, in the Bono Region. Convenience and purposive sampling techniques were used to select ten (10) healthy adults for blood glucose tests in this study. Materials used for the study were Fresh cassava, plantain, yam, and cocoyam. Descriptive analysis was used in analysing and interpretation of the data. Values were analyzed by one-way analysis of variance (ANOVA). Statistical significance was set at p<0.05. Statistical analysis was performed using Statistical Package for Social Science (SPSS) 20.0. Proximate analysis of the study concluded that, plantain fufu contained the least carbohydrate content among the three fufu mixtures. The study also revealed that all fufu combinations had a high glycaemic load and this is as a result of the large portion size of fufu that is eaten at a serving. The glycaemic load of fufu combinations showed no significant difference, however, looking at the actual values, there are differences in them which should not be overlooked. It is recommended that consumers of fufu can eat any of the three mixtures of fufu, but there will be the need to take a smaller portion size of the fufu since a larger size can have adverse effects on their blood glucose level. It is also recommended that in other for fufu to be digested well and glucose to be absorbed easily, especially yam fufu, consumers should make sure to eat fufu at least about five hours before going to bed. It is recommended that nutritionists, dieticians, and diet therapists can as well recommend yam fufu and cocoyam fufu for diabetics and prediabetics, to bring about varieties in their diet.

The tensile strength is an imperative properties and essential indications consumers’ look out for in purchasing a quality fabric. The objective of this study was to examine key soap on tensile strength in three washing cycles of selected Printex fabrics in Ghana. Quantitatively, the study adopted both experimental and factorial research designs. Materials for the study consisted of three fabrics with black prints and white as base colour were purchased from the market. These three fabrics had the same designs but two had different fabric finishes and the third one had no finish (plain, embossed and plisse). Six yards each of the Printex black and white fabrics with embossed, plisse and a third one which did not have any special fabric finish were used for the study. Key soap purchased from the Ghanaian market, and standard soap from Ghana Standard Authority was used for the study. Purposive and simple random techniques were used to select materials for the study. The main research instrument for the testing tensile strength was Universal tensile testing machine. Data were analysed with both descriptive and inferential statistics. The one-way analysis of variance (ANOVA) was used to test the hypothesis formulated to guide the study. The study revealed that continuous washing had degrading effects on the tensile strength. The implication is that continuous washing weakens the internal strengths of fabrics which cause them to fail or weakens their resistance to stress test. The study also found that continuous washing had degrading effects on the tensile strength of the selected fabrics. It is recommended that the Ghana Standards Authority should encourage soap producers to get their chemical compositions as close to those of the standardised soap as possible.

Background: Multiple epiphyseal dysplasia (MED) a rare form of skeletal dysplasia with early-onset osteoarthritis affecting the hip and knee joints. There is paucity of evidence regarding the long term outcomes of arthroplasty in this patient cohort. This is the first study to describe the outcomes of bilateral arthroplasty of the hip and knee in patients with MED. Methods: A prospective study of patients with MED who underwent bilateral staged total hip arthroplasty (THA) and bilateral simultaneous total knee arthroplasty (TKA) between July 2013 to April 2014. Preoperative and postoperative clinical and radiographic assessment including functional outcomes namely Merle d’aubigne score, Harris hip score (HHS), Knee society score (KSS) and numeric rating scale (NRS) for pain were recorded in prospective database and evaluated. Results: 3 patients (female - 1 / male - 2) with MED who underwent bilateral lower limb arthroplasty of the hip and knee were reviewed periodically with an average followup of 7.31 years. Mean preoperative Merle d'Aubigné score (6.33 ± 0.58), HHS (31.83 ± 5.31) and KSS (28.67 ± 7.97) increased following bilateral lower limb arthroplasty with mean postoperative Merle d'Aubigné score (16.33 ± 0.58), HHS (84.33 ± 5.99) and KSS (86.33 ± 7.09) (P<0.001). Mean NRS decreased from 7.33 ± 0.58 in the preoperative period to 0.67 ± 0.58 at the most recent followup (P<0.001). One patient had heterotrophic ossification following THA. There were no revisions. Conclusions: Bilateral lower limb arthroplasty of the hip and knee is a good treatment option to restore function and mobility in MED patients with advanced degenerative arthritis. Careful preoperative planning, meticulous surgical techniques, patient focussed postoperative rehabilitation with multidisciplinary team approach are vital to ensure good functional outcomes and implant survivorship.

The therapeutic effect of Cyclophosphamide (CPA) is thus attributed to phosphoramide mustard and acrolein leads to the formation of high levels of reactive oxygen species (ROS), which results in decreased antioxidant activity. Excessive production of ROS could also culminate in oxidative stress. Objectives: This study aims to evaluate the effect of sub-lethal dose of the cyclophosphamide, 5-FU, combination of 5-FU, and CPA on testicular antioxidant status, and oxidative stress in male albino rats. Materials and Methods: Twenty-eight male adult rats were grouped randomly into four groups (n=5 each group). Group I (control): Rats were injected with saline intraperitoneally and at a dose of 1.0 ml/kg b.w. for 14 days. Group II cyclophosphamide (CPA): Cyclophosphamide at a dose of 10 mg/kg day by day through i.p. to rats for 14 days. Group III Fluorouracil (5-FU): 5-Fluorouracil at a dose of 10 mg/kg day by day in saline was given through i.p. to rats for 14 days. Group IV (CPA+5-FU): Rats were given CPA followed by 5-FU at a dose of 10 mg/kg per day (day by day) through i.p. to rats for 14 days. At the end of the experimental period, rats were anesthetized using light ether. Blood and testes tissue samples were taken and prepared for biochemical measurements. Biochemical parameters in rat serum and tissues were evaluated. Results: Individual injection of CPA and 5-FU to rats were reduced testes TAC, GSH concentration, GR, and CAT activities compared to control. However, the combination treatment of rats with 5-FU and CPA increased the levels of these non-enzymatic and enzymatic antioxidant compared with those treated with CPA alone. Also, results showed significantly increased TBARS and NO concentration in the testes of CPA treated rats when compared to normal ones, while 5-FU increased NO only compared with the control. Conclusion: It can be concluded that treatment of rats with CPA is associated with the production of free radicals that leads to hazardous alterations in certain non-enzymatic, and enzymatic functions. The increase in lipid peroxidation probably leads to the intracellular accumulation of ROS with the subsequent development of testes tissue injury. However, 5-FU and CPA combination could produce a significant amelioration in most cases for these changes, and it may be considered as a potentially useful candidate in the combination chemotherapy with CPA to combat oxidative stress mediated non target organs injury even if it was not a complete protection. Future work should consider combined chemotherapy regimens, as two or more mechanisms of action of chemotherapeutic drugs could be more powerful than one mechanism.

Giant cell arteritis (GCA) with ocular involvement is an emergency condition, and treatment with glucocorticoids should be provided immediately upon clinical suspicion of GCA to prevent potential blindness. In this case report, we discuss a case of a 70-years-old Caucasian male presented to the emergency department with one day sudden onset of double vision. This is a teaching case report aimed to discuss the management options, potential complications and visual prognosis of this particular case.

Background: Cyclophosphamide (CPA) induces acute inflammation of the urinary bladder, renal damage, and liver damage, thereby limiting its therapeutic use. Objectives: The present study aimed to evaluate the hepatorenal toxicity induced by cyclophosphamide and amelioration by 5-fluorouracil in male albino rats. Materials and Methods: Twenty-eight male adult rats were grouped randomly into four groups (n=5 for each group). Group I (control): Rats were injected with saline intraperitoneally and at a dose of 1.0 ml/kg b.w. for 14 days. Group II cyclophosphamide (CPA): Cyclophosphamide at a dose of 10 mg/kg day by day through i.p. to rats for 14 days. Group III Fluorouracil (5-FU): 5-Fluorouracil at a dose of 10 mg/kg day by day in saline was given through i.p. to rats for 14 days. Group IV (CPA+5-FU): Rats were given CPA followed by 5-FU at a dose of 10 mg/kg per day (day by day) through i.p. to rats for 14 days. At the end of the experimental period, rats were anesthetized using light ether. Blood samples were taken and prepared for biochemical measurements. Results: Serum total protein, albumin, and globulin concentration significantly reduced in animal groups that received cyclophosphamide. 5-FU and CPA combination reduced the changes in total protein, albumin, and globulin compared to CPA treated group. A significant increase in LDH serum concentration was found in CPA, 5-FU, and their combination-treated animals. The mean values of the combination of chemotherapy were above that in CPA followed by 5-FU treatment. Administration of CPA, 5-FU resulted in a significant increase in serum AST, ALT, ALP, and bilirubin compared to the control. Co-treatment 5-FU with CPA significantly attenuated the increase in serum AST, ALT, ALP, and bilirubin when compared to CPA – treated rats. Compared to controls, urea and creatinine levels were increased in CPA-treated rats, while uric acid was reduced in CPA, 5-FU, and their combination. The changes in urea and creatinine produced by the chemotherapy were restored when rats received CPA in combination with 5-FU. Conclusion: It could be concluded that the treatment of mammals with chemotherapy is associated with the production of free radicals that lead to hazardous alterations in biochemical parameters. However, 5-FU and CPA combination could produce a significant amelioration in most cases for these changes, and it may be considered as a potentially useful candidate in the combination chemotherapy with CPA to combat oxidative stress-mediated non-target organ injury even if it was not complete protection. Future work should consider combined chemotherapy regimens, as two or more mechanisms of action of chemotherapeutic drugs could be more powerful than one mechanism. Toxicological studies must be performed before using drugs as a combination before application. Further research is required on the toxicological impacts of drugs and pollutants mixtures.

Groundwater geochemistry refers to the general chemical properties of water, particularly groundwater. Precipitation, volatilization, oxidation/reduction, sorption/partition, and complexation are processes involved in the distribution and fate of organic molecules in water. Determining hydrogeochemical facies is a great help for determining relationships and similarities among the chemistry of waters in an aquifer. This study focused on the coastal aquifer of Tripoli (Lebanon) with Mio-Quaternary age. It is considered as a confined aquifer and an important hydraulic reserve for domestic water use in the region. Recently, it underwent an urban development that leads to an increase in water demand causing a decrease in the piezometric level and a high-risk of deterioration to water quality through seawater intrusion and anthropic pollution. To understand the origin of mineralization and the mechanism of water hydro-chemistry variation and to provide a vision to underground water recharge, this study aims to analyze the hydrodynamic, piezometric, and geochemical characteristics of the coastal aquifer. The fluctuation of physicochemical parameters for cool and warm seasons has been studied and monitored for 16 coastal wells during April, May, and June 2020. Results were interpreted by using a statistical analysis called Principal Components Analysis (PCA). Cartographic of groundwater levels and concentrations for nitrate, chloride, sulphate ions, the ratio sulphate/chloride were determined by using SUFFER8 software. It can be noticed that the Mio-Quaternary formation at Tripoli consists of thick sedimentary sandstones and conglomerates with argillaceous roots, which provide significantly high permeability characteristics. It is mainly recharged from precipitations through karstic formations. Chemical analysis shows that bicarbonate ions (HCO₃^-), characterized by dissolution of carbonate rocks from geological upstream formations of Tripoli, means that the aquifer is subjected to intensive recharge of fresh water and snow melting making a hydrostatic equilibrium facing marine intrusion [1]. High contents of chloride and Sodium are due to anthropic contamination or seawater intrusion. However, Magnesium ion concentration assures this intrusion. Meanwhile, nitrates, sulfates and phosphorus high concentrations are related to wastewater leakage or agricultural activities [2].

The purpose of the study was to examine technological pedagogical content knowledge of teachers and their formative assessment practices in Social Studies lessons in the Junior High Schools in the Komenda Edina Eguafo Abirem (K.E.E.A) Municipality of Ghana. With a mixed method approach, the study adopted a descriptive survey research design. The population for the study included all Social Studies teachers at the public junior high schools in the in the Komenda Edina Eguafo Abirem Municipality. Purposive sampling technique was used to select all the seventy-four (74) public Junior High Schools and the Social Studies teachers for the study. The purposive sampling technique was used to sample the respondents because they constitute expert knowledge in the subject area and having the same characteristics. The two main instruments used to gather data for the study were questionnaire and observation. Data was analysed using descriptive and inferential statistics. The study indicated that the assessment practices of teachers during Social Studies lessons were on the average. There was disparity between theory and practice as far as the dictates of the profile dimensions are concerned. Teachers mostly assess the cognitive aspect of the child with little attention to the affective domain. The study also concluded that there was a significant positive relationship between TPACK of teachers and their formative assessment practices at 0.05 level of significance. It is recommended that Ministry of Education, National Teaching Council, Ghana Education Service should organize professional development workshop for teachers on their formative classroom assessment practices in Social Studies lessons. It is also recommended that, in order to ensure effective formative assessment practices, Ghana Education Service should collaborate with Colleges of Education and Universities training teachers to develop appropriate TPACK for teachers to improve on their formative assessment practices in the classroom.

The Blockchain technology uses different type of database that transact data in blocks and then chained each data blocks. When data fills one block, it is chained the same data onto previous block therefore, all the data blocks are stored in chronological order. The blockchain technology can help to ensure that data in supply chain is reliable, accurate and can be shared with all stakeholders without any manipulation. It makes supply chain more transparent and end-to-end digital visibility of data source. Blockchain is stringent technology which fill the gap between stakeholders by providing transparent unmanipulated and truthful data in supply chain. There are many initiatives has been taken by multiple regulatory bodies with partnering with supply chain stakeholders including pharmaceutical manufacturer, distributors and dispensers. In USA, Food and Drug Administration’s regulatory body Drug Supply Chain Security Act (DSCSA) initi-ated pilot program in 2019 with the partnership of leading pharmaceuticals distributors to au-thenticating saleable returns to distributor from supply chain partners. DSCSA used MediLedger blockchain interoperable technology for process evaluation and it robustness for mitigating risk of drug counterfeiting possibilities in supply chain. The DSCSA found that pilot project was suc-cessful and results were astonishing. Later it was declared that blockchain technology can also be used for meeting DSCSA’s 2023 Act for unit level traceability.

Streptococcus pneumoniae is an important pathogenic bacteria causing pneumonia and invasive pneumococcal diseases, and the vaccination for pneumococcal vaccination is recommended in patients with RA and other autoimmune disorders. Compared with the immunocompetent individuals, frequency and the mortality rate were higher in the RA patients. The effect of pneumococcal vaccination may not be weakened in people using corticosteroid and biological disease-modifying anti-rheumatic drug (DMARD) currently being used, but mild to relatively inhibition of immunogenicity was suggested in patients using either methotrexate or rituximab. Administration of 13-valent pneumococcal conjugate vaccine (PCV13), rather than 23-valent Pneumococcal polysaccharide vaccine (PPSV23) may be desirable in preventing pneumonia in people with autoimmune disease and sequential administration of PCV13 in people aged ≤64 years and PPSV23 from age ≥65 years may be useful for preventing pneumonia in people with autoimmune disease according to the insurance system. In addition, PCV15 and PCV 20 will be available soon and expected for more clinical efficiency rather than current PCV13 and PPSV23.

Coronavirus infection (COVID-19) has quickly emerged as a global pandemic leading to critical health complications. The possibility and risk of vertical transmission of this virus is still unclear, particularly as it relates to pregnant women and their fetuses. Regarding scientific data, there is insufficient research focused on COVID-19 infection complicated with hydrops fetalis and intrauterine fetal demise. In this study, we report an intra uterus fetal death due to hydrops fetalis and twin-to-twin transfusion syndrome (TTTS) in monochorionic–monoamniotic (MCMA) twin pregnancy associated with mild COVID-19 infection in a 33-week-pregnant woman.

Background: Cyclophosphamide (CPA) is a drug with a wide spectrum of clinical uses. Its effectiveness in the treatment of cancer (acute and chronic leukemias, lymphoma, and multiple myeloma) and non-malignant diseases such as rheumatoid arthritis and vasculitis has been well established. Objectives: The present investigation aimed to study the effect of a sub-lethal dose of the cyclophosphamide, 5-FU combination of 5-FU, and CPA on haematological parameters in the albino rats. Materials and Methods: Twenty-eight male adults were grouped randomly into four groups (n=5 in each group). Group I (control): Rats were injected with saline intraperitoneally at a dose of 1.0 ml/kg b.w. for 14 days. Group II cyclophosphamide (CPA): Cyclophosphamide at a dose of 10 mg/kg day by day through i.p. to rats for 14 days. Group III Fluorouracil (5-FU): 5-Fluorouracil at a dose of 10 mg/kg day by day in saline was given through i.p. to rats for 14 days. Group IV (CPA+5-FU): Rats were given CPA followed by 5-FU at a dose of 10 mg/kg per day (day by day) through i.p. to rats for 14 days. At the end of the experimental period, rats were anesthetized using light ether. Blood samples were taken for hematological evaluation. Results: White blood cells, hemoglobin content and red blood cell counts were significantly decline in rats treated with individual treatment with CPA and 5-FU in comparison to the control group, while the Combination antagonize the changes produced by CPA in hemoglobin and red blood cell counts. Intraperitoneal individual treatment with CPA and 5-FU in rats caused a significant reduction in the hematocrit and platelet. The reductions in these measured hematological parameters were also significantly and slightly ameliorated when the animals were given a combination of CPA and 5-FU. Cyclophosphamide and 5-FU individually reduced lymphocytes, neutrophils, eosinophils, and monocytes; while the combination of CPA and 5-FU antagonized these changes compared to CPA treated group. Conclusion: It could be concluded that the treatment of mammals with chemotherapy is associated with the production of free radicals that lead to hazardous alterations in hematological parameters. However, 5-FU and CPA combination could produce a significant amelioration in most cases for these changes. Future work should consider combined chemotherapy regimens, as two or more mechanisms of action of chemotherapeutic drugs could be more powerful than one mechanism. Using cyclophosphamide and 5-fluorouracil in combination may reduce cyclophosphamide’s side effects when given individually.

The healthcare access is fundamental rights for every human being. It is Governments responsibility to provide good healthcare services and infrastructure to its citizen. Since last few decades, Government and healthcare industries are struggling to minimize the adverse events impacting people health due to fake medicine. The world health organization also predicted that 4 out of 10 medicines in developing and poor countries are either fake or potentially adulterated. Counterfeit drugs cost billions of dollars deficit to world economy and reduce research and development (R&D) funds allocation from organizations. Stopping counterfeit medicine into supply chain is main challenge for Government and regulatory authorities. The Government and regulatory authorities are now making stringent guidelines to prohibit criminals and counterfeiters to supply fake medicine in markets. Healthcare industry need stringent regulations and secure technologies provide sage and authentic drugs to patients. The FDA has published the 10 years roadmap to implement the drug traceability in United States. The Healthcare Distribution Alliance (HDA) has also mandated to print several barcodes and human readable data in product packaging hierarchy. The FDA is participating in pilot project with leading pharmaceutical drug manufacturer and wholesales to use blockchain technology in interoperable digital network for securing digital traceability data transfer between authorized trading partners.

The purpose of the study was to examine the Motives of Tourists; Socio-Economic and Challenges of tourism in Kwahu in the Eastern Region of Ghana The study adopted a descriptive survey research design. The population of the study comprised six (6) communities (Mpraeso, Atibie, Obomeng, Obo Oworobong, and Nketepa in Kwahu South District Assembly (KSDA) in the Eastern Region of Ghana. Purposive and convenient sampling techniques were employed to select two hundred (200) respondents for the study. The main instrument used for data collection was questionnaires. The study employed the statistical package for social sciences (SPSS) to code and process the collected data. Descriptive and relational statistical techniques involving frequencies, percentages, summations, diagrams, and tables were employed in analysing the data. The Chi-square test analysis was used to explore the relationships and differences in perceptions. The study indicated that every tourist, whether local (Ghanaian) or foreign, had at least one of the following motives in mind for participating in the festival; To socialize; For relaxation; For education to participate and witness the paragliding festivals; To take photographs of festival scenes; Other motives like to sell items, especially souvenirs. The study also revealed that the KEF has had some positive socio-economic impact or implications on the area. These among others include: job creation, income generation for locals of the area, infrastructural development, and projection of the image of the area as the festival has become one of the biggest gatherings of revellers in the country, drawing people from all walks of life, nationally and internationally as a result of the introduction of paragliding since 2005, socialization enhancement, medium for cultural exchange and education, and finally serves as a medium for portraying the cultural identity of the people of Kwahu. The study also indicated that the major challenges encountered by tourists during the event were listed in order of degree of intensity: High cost of living, poor road network in the area, intermitted electricity and water supply, poor sanitary conditions in the area, poor health facilities, and unwelcoming attitude of some local residents of the festival area. It is recommended that, residents must be educated about the potential benefits of tourism as an industry helping to achieve sustainable community development. It is also recommended that Ghana tourism authority and Kwahu District Assembly should collaborate to improve on social amenities in the municipality to attract more foreign and local tourists during the festivity.

The purpose of the study was to examine the knowledge base of students in the Assin Manso Senior High School in the central region of Ghana. A qualitative method was used in this study. The population of the study comprised students from Assin Manso senior high school in the Central Region of Ghana. Purposive sampling technique was employed to select forty (40) respondents for this study. The forty (40) respondents consisted of all Students Representative Councils (SRC) members in the school. Each class has a representation in the study. The main instrument for data collection was interview guide. The data collection was done using Interpretative Phenomenological Analysis (IPA). The qualitative data was analysed by the use of the interpretative technique based on the themes arrived at during the interview. The themes were related to the research question. The study revealed that honesty is being loyal to a colleague, covering them up and standing by them as well. The study also indicated that honesty depict “we feeling” or “solidarity”, so to them any students who does the opposite is considered to be dishonest. It is recommended that, Students who obey the school rules and regulations should be motivated by the school authorities in order to encourage the other students to do same. It is also recommended that parents and educators, should all advocate the teaching of moral values in our schools to instil in students the benefits that honest brings to them, the school, the family, community and the country as a whole.

The purpose of the study was to examine the perceptions and effective implementation of peace education in Senior High Schools in Ekumfi District in the Central Region of Ghana. The study was underpinned by the Integrative Theory of Peace Education (ITPE) [1]. The study adopted the mixed methods approach where the exploratory sequential mixed method design was employed. The convenience and stratified random sampling techniques were used to select 20 and 350 participants for the qualitative and quantitative stages of the study respectively. Semi-structured interview guide and questionnaire were the main tools used to collect data for the study. The qualitative data were analyzed through the thematic approach with the help of NVivo 12 Plus while the quantitative data were analyzed using descriptive statistics like mean, frequency, and standard deviation with the aid of SPSS version 20. The study indicated that peace education in the schools is relevant in mentoring students who would be advocates of peace in their respective communities, preparing future leaders who are required to uphold peace and espouse peaceful attributes in their dealings with the publics as well as championing the path of national development. The study also revealed that teachers needed to be trained on the principles, knowledge, and skills required to effectively deliver peace education in the schools. The point is made that when these challenges are tackled, it will pave the way for the smooth implementation of peace education in the schools. It is recommended that peace education should be accorded the needed importance in the school curriculum. It is also recommended that the management of the schools should design and implement co-curricular programmes that are tailored towards the delivery of peace education to the students. It is further recommended that the National Council for Curriculum and Assessment (NaCCA) of the Ghana Education Service should incorporate peace education as a topic in the Social Studies curriculum as part of the curriculum reforms for the Senior High Schools in Ghana.

In this Research work, Silver Nanoparticles were green synthesized from Psidium guajava leaves and different Characterization techniques including UV-Visible, FT-IR, SEM and XRD were all employed to ascertain the absorption peaks, functional group, surface morphology and crystalline size of the nanoparticles respectively. These nanoparticles green synthesized were applied against four different pathogens namely, S. aureus (gram- positive bacteria), E. coli (gram- negative bacteria), C. albicans (gram- positive fungus) and Aspergillus niger and the investigation showed that the Silver nanoparticles synthesized were potent against the selected pathogens. From the UV-Vis spectral analysis, it was observed that highest absorption peaks appeared at 400nm and 500nm reflecting the surface plasmon resonance of silver Nanoparticles from guava leaves which is characteristic of Silver Nanoparticles. From the FT-IR spectrum of the sample under studied, the peaks 3416.85 cm^-1, 2923.51 cm^-1, 1618.95 cm^-1, 1384.49 cm^-1 and 1033.63 cm^-1 were observed where the absorption band at 3416.85 cm^-1 corresponds to the stretching due to N-H, while the band at 2923.51 cm^-1 is associated with C-H stretch of alkane and O-H stretching. The peak at 1618.95 cm^-1 shows C=C stretching, 1384.49 cm^-1 reveals the existence of C-H bending and 1033.63 cm^-1 depicted C-O stretching. The SEM analysis revealed the shape of the nanoparticles as being spherical while XRD result admits that the average size of the green synthesized Ag NPs was 45.5 nm using the Scherer’s formula. Augmentin was used as control at concentration of 300μg/L throughout antimicrobial studies. Different concentrations of 100, 200, 300, 400 and 500μg/L of Silver Nanoparticles were tested against each pathogen. It was discovered that with increase in concentrations of Silver Nanoparticles of all the pathogens, there generally appeared to be increase in inhibition zone. At higher concentration of 500μg/L, the zones of inhibition were in the following order; 22.50 mm, 17.00mm, 15.44mm, and 13.23mm for E. Coli, S. aureus, C. albicans and Aspergillus niger respectively. For each concentration investigated, E. coli, demonstrated higher zone of inhibition as opposed to all other pathogens investigated in this research.