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Open Access February 06, 2026

Predictive Modeling of Public Sentiment Using Social Media Data and Natural Language Processing Techniques

Abstract Social media platforms like X (formerly Twitter) generate vast volumes of user-generated content that provide real-time insights into public sentiment. Despite the widespread use of traditional machine learning methods, their limitations in capturing contextual nuances in noisy social media text remain a challenge. This study leverages the Sentiment140 dataset, comprising 1.6 million labeled [...] Read more.
Social media platforms like X (formerly Twitter) generate vast volumes of user-generated content that provide real-time insights into public sentiment. Despite the widespread use of traditional machine learning methods, their limitations in capturing contextual nuances in noisy social media text remain a challenge. This study leverages the Sentiment140 dataset, comprising 1.6 million labeled tweets, and develops predictive models for binary sentiment classification using Naive Bayes, Logistic Regression, and the transformer-based BERT model. Experiments were conducted on a balanced subset of 12,000 tweets after comprehensive NLP preprocessing. Evaluation using accuracy, F1-score, and confusion matrices revealed that BERT significantly outperforms traditional models, achieving an accuracy of 89.5% and an F1-score of 0.89 by effectively modeling contextual and semantic nuances. In contrast, Naive Bayes and Logistic Regression demonstrated reasonable but consistently lower performance. To support practical deployment, we introduce SentiFeel, an interactive tool enabling real-time sentiment analysis. While resource constraints limited the dataset size and training epochs, future work will explore full corpus utilization and the inclusion of neutral sentiment classes. These findings underscore the potential of transformer models for enhanced public opinion monitoring, marketing analytics, and policy forecasting.
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Open Access August 26, 2025

The association between serum α1-AGP and chronic kidney disease among US female ages 20 to 49 years: Results from the 2015-2018 National Health and Nutrition Survey

Abstract Background: Chronic kidney disease (CKD) affects over 35.5 million US adults. Serum α1-acid glycoprotein (α1-AGP), an acute-phase protein, exhibits anti-inflammatory properties in animal models, but its association with CKD in younger women remains underexplored. This study investigated the relationship between serum α1-AGP and CKD risk in US women aged 20–49 years. Methods: This [...] Read more.
Background: Chronic kidney disease (CKD) affects over 35.5 million US adults. Serum α1-acid glycoprotein (α1-AGP), an acute-phase protein, exhibits anti-inflammatory properties in animal models, but its association with CKD in younger women remains underexplored. This study investigated the relationship between serum α1-AGP and CKD risk in US women aged 20–49 years. Methods: This nationally representative cross-sectional study used data on female adults in the US aged 20–49 years from the National Health and Nutrition Examination Survey 2015–2018 cycles. 2,137 individuals were included in the study after excluding individuals without serum α1-AGP, urine albumin, and creatinine data. Multivariate logistic regression models evaluated the association between serum α1-AGP and CKD. Moreover, we performed stratified and interaction analyses to see if the relationship was stable in different subgroups. Results: Among 2,137 participants (mean age 34.6 years, mean eGFR 111.7 mL/min/1.73 m²), CKD prevalence was 8.8% (n=188). Higher serum α1-AGP levels were associated with lower CKD risk in the fully adjusted model (OR 0.37, 95% CI 0.16–0.84, P = 0.017), with a dose-response trend across quartiles (P = 0.041). The association was stronger in women aged 40–49 years (OR 0.20, 95% CI 0.05–0.76) and Mexican Americans (OR 0.07, 95% CI 0.01–0.56), though interaction terms were not significant (P > 0.05). Conclusions: Higher serum α1-AGP levels are associated with lower CKD prevalence in young women, suggesting a protective role. Longitudinal studies are needed to confirm causality and explore α1-AGP as a biomarker for CKD risk stratification.
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Open Access March 03, 2025

Effectiveness and Safety of Acupuncture Combined with Bloodletting Cupping Therapy in the Treatment of Scapulohumeral Periarthritis: A Systematic Review and Meta-Analysis

Abstract Background: Scapulohumeral periarthritis commonly afflicts individuals in their middle age. Its etiology is multifaceted, and treatment presents a challenge with a high risk of recurrence. The main symptoms include shoulder pain and limited joint mobility, seriously affect the quality of life of the patients. Recent research indicate that acupuncture combined with bloodletting cupping can [...] Read more.
Background: Scapulohumeral periarthritis commonly afflicts individuals in their middle age. Its etiology is multifaceted, and treatment presents a challenge with a high risk of recurrence. The main symptoms include shoulder pain and limited joint mobility, seriously affect the quality of life of the patients. Recent research indicate that acupuncture combined with bloodletting cupping can significantly improve the function of activity of shoulder joint and the pain in individuals with scapulohumeral periarthritis. However, these studies have typically been limited in scope, therefore additional research to substantiate the efficacy and safety of these intervention. Methods: To evaluate the efficacy of acupuncture combined with bloodletting cupping for treating patients with scapulohumeral periarthritis. We conducted an online search of databases in both Chinese and English, including PubMed, the Cochrane Library, Embase, Web of Science, CNKI, Wangfang Data, China Science and Technology Journal Database (VIP) and Chinese BioMedical Literature Database (CBM), to collect randomized controlled trials (RCTs) concerning the use of acupuncture combined with bloodletting cupping in scapulohumeral periarthritis patients. We also examined the references within the identified literature. Search utilised subject headings and free-text terms in both languages, without racial restrictions, for records up to April 3, 2024. Two researchers independently screened the literature, extracted data, and evaluated their qualities. RevMan 5.3 software was used for meta-analysis of the included studies. The protocol of this review was recorded in the International Platform of Registered Systematic Review and Meta-analysis Protocols (PROSPERO). Its registration number is CRD42023454614. Results: This review incorporated 22 RCTs involving a total of 1,774 patients. The results of meta-analysis showed that the clinical effective rate (RR=1.25, 95%CI [1.20, 1.30], P<0.00001) of treating scapulohumeral periarthritis with acupuncture combined with bloodletting cupping was higher in the experimental group than in the control group. The all of Visual Analogue Scale (VAS) score (MD=-1.70, 95% CI [-2.17, -1.22], P<0.00001). Melle score (SMD=-2.45, 95% CI [-2.55, -2.34], P=0.007]) and recurrence rate (RR=0.23, 95% CI [0.07, 0.77], P=0.02) were lower in the experimental group than in the control group with statistical significance (P<0.05). Conclusion: The acupuncture combined with bloodletting cupping for the treatment of shoulder impingement syndrome demonstrates definite efficacy and safety, with superior clinical effectiveness, pain relief, improvement in shoulder joint mobility, and reduction in recurrence compared to acupuncture alone. Therefore, it is worthy of being promoted and applied clinically.
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Meta-Analysis
Open Access January 04, 2025

Knowledge Level of Street Fruit Vendors on Food Hygiene in the Tamale Metropolis

Abstract This study aimed to assess the knowledge level of street food vendors on hygiene in the Tamale metropolis in the Northern Region of Ghana. The study employed the health belief model as the theoretical basis. Quantitatively, the study employed a descriptive cross-sectional study design to examine the microbial load of street-cut fruits and assess the knowledge and practice of vendors of cut fruits [...] Read more.
This study aimed to assess the knowledge level of street food vendors on hygiene in the Tamale metropolis in the Northern Region of Ghana. The study employed the health belief model as the theoretical basis. Quantitatively, the study employed a descriptive cross-sectional study design to examine the microbial load of street-cut fruits and assess the knowledge and practice of vendors of cut fruits on personal and food hygiene in the study setting. The population consists of cut and vented pawpaw, watermelon, and street fruit vendors registered with the health directorate in the Tamale Metropolis. A convenient sampling technique was used to select 113 respondents for the study. The Yamane formula was used to determine the sample size to select one hundred and thirteen participants (113) out of one hundred and fifty-eight street fruit vendors in the Tamale Metropolis. The main instrument for data collection was a questionnaire. A questionnaire had close-ended questions which were developed using a 'Yes' and 'No' response, and a four-point Likert-type scale ranging from 1=Strongly Disagree (SD), 2=Disagree (D), 3=Agree (A) and 4= Strongly Agree (SA). The data were analysed using descriptive statistics (frequency, percentages, means and standard deviation). The findings revealed that the overall knowledge level of respondents is low. The findings also indicate that vendors do not control the rate at which their customers touch their vended fruits. It is recommended that Street fruit vendors and handlers be educated on fruit hygiene practices through engagement by the Health Directorate Unit of Tamale Metropolis and the Ministry of Health. To keep consumers safe, the Tamale Metropolitan Assembly must strictly enforce compliance with regulations on operation permits and health clearance certificates. Metropolitan sanitation officers must regularly monitor fruit vendors to ensure compliance with goods.
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Open Access October 31, 2023

Effectiveness of Probiotics for Treatment of COVID-19: A Systematic Review and Meta-analysis

Abstract Background: Recently specific interactions and crosslinks between the gut microbiota and the lungs have been recognized, particularly with regard to respiratory immune and anti-microbial reactions. This is often known as the “gut-lung axis” or “a common mucosal immunological system”. Objective: The aim of the current systematic review was to evaluate evidence, from published clinical trials and cohort studies, if probiotics may have an effect in improving and managing COVID-19 symptoms. Materials and methods: The available studies were searched through a comprehensive search of electronic databases that included PubMed, Science Direct, Scirus, ISI Web of Knowledge, Google Scholar and CENTRAL (Cochrane Central Register of Controlled Trials), using a combination of the following keywords: “COVID-19" OR [...] Read more.
Background: Recently specific interactions and crosslinks between the gut microbiota and the lungs have been recognized, particularly with regard to respiratory immune and anti-microbial reactions. This is often known as the “gut-lung axis” or “a common mucosal immunological system”. Objective: The aim of the current systematic review was to evaluate evidence, from published clinical trials and cohort studies, if probiotics may have an effect in improving and managing COVID-19 symptoms. Materials and methods: The available studies were searched through a comprehensive search of electronic databases that included PubMed, Science Direct, Scirus, ISI Web of Knowledge, Google Scholar and CENTRAL (Cochrane Central Register of Controlled Trials), using a combination of the following keywords: “COVID-19" OR "SARS-CoV-2" AND "Microbiota" OR "Probiotics” OR “Gut Lung Axis”. The literature was reviewed until August 31, 2022. Results: Only 3 studies were included. One of them evaluated the efficacy of probiotics in COVID-19 patients to obtain complete remission of all signs and symptoms. The clinical trial proves that probiotics have a significant effect on complete remission of all signs and symptoms of COVID-19 patients with statistical significant difference. Only one clinical trial out of the 3 included studies had evaluated the need for O2 therapy during the study between the probiotics and control groups, but without statistical significant difference. No statistical significant difference between the probiotics group and placebo group was observed regarding fatal prognosis during the only clinical trial that measured death as an outcome. Conclusion: We couldn’t judge on these results as they are insufficient data for pooling and meta-analysis. However, what we can say is “Most probably Probiotics have no role in treatment of COVID-19 infection”.
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Meta-Analysis
Open Access September 20, 2023

Group-specific Differences in Blood Lead Levels among Occupationally Exposed Workers in Greater Banjul Area, The Gambia

Abstract Occupational lead (Pb) exposure continues to be an important public health problem globally, yet data is lacking on the associated risks and resources available for the prevention of Pb related diseases in low middle income countries (LMICs) like The Gambia. In this study, we used a case-control design to compare blood lead levels (BLLs) between the exposed (auto repair workers) and unexposed [...] Read more.
Occupational lead (Pb) exposure continues to be an important public health problem globally, yet data is lacking on the associated risks and resources available for the prevention of Pb related diseases in low middle income countries (LMICs) like The Gambia. In this study, we used a case-control design to compare blood lead levels (BLLs) between the exposed (auto repair workers) and unexposed (healthcare workers) populations in The Greater Banjul Area. The data was analyzed using Chi square test of independence to determine the characteristic factors associated with BLL. Multivariate logistic regression was used to test the relationship between BLLs for auto repair and healthcare workers and their experiences. The results of this study indicated 82.1% of cases had higher BLLs compared to 52.9% of controls. Also, the proportion of workers with elevated BLLs was higher for certain factors including more than 80% of those with greater than 10 of years job experience, more than 70% of those who worked greater than 5 days a week, worked more than 8 hours per day, did not use personal protective equipment (PPE), were illiterate or had no formal education, and smoked or ate at work. The study results have implications for policies and practice in the auto repair industry and related workplaces in The Gambia and other LMICs with similar settings. Based on the findings of this study, it is essential to initiate discussions to establish national occupational health policies in The Gambia aimed at protecting workers and the general population.
Article
Open Access September 17, 2023

Knowledge and practice of diabetic foot prevention among diabetic patients attending Edward Francis Small Teaching Hospital, Banjul, The Gambia: an institutional-based cross-sectional study

Abstract Background: The increasing prevalence of Diabetes Mellitus (DM) is closely tied to complications, particularly diabetic foot ulcers, which significantly raise the risk of lower extremity amputations due to infected, non-healing ulcers. This study aimed to assess diabetic foot prevention knowledge, practices and associated factors among patients at the Edward Francis Small Teaching Hospital [...] Read more.
Background: The increasing prevalence of Diabetes Mellitus (DM) is closely tied to complications, particularly diabetic foot ulcers, which significantly raise the risk of lower extremity amputations due to infected, non-healing ulcers. This study aimed to assess diabetic foot prevention knowledge, practices and associated factors among patients at the Edward Francis Small Teaching Hospital (EFSTH), Banjul. Methods: In this cross-sectional study, we employed a convenience sampling technique to enroll 357 diabetic patients, both inpatients and outpatients, who were under the care of EFSTH. Data on diabetic foot prevention were collected through semi-structured interviews conducted by trained interviewers. Statistical analyses were carried out using SPSS, encompassing descriptive analysis, chi-square, Fisher exact tests, and logistic regression. Statistical significance was set at p<0.05, with a 95% confidence interval. Results: The mean age of the respondents was 47.3 years (±10.5), with women comprising 55.2% of the study population and 94.4% were married. About 73% demonstrated good knowledge of diabetic foot care and prevention, while 25.8% exhibited fair knowledge. A significant association was observed in bivariate analysis with patients’ educational level (P = 0.032). Specifically, patients with Madarasa (Arabic) education had a 68% lower likelihood 【aOR: 0.320, 95% CI: (0.103, 0.992), p = 0.048】 of practicing diabetic foot care and prevention compared to those with tertiary education. Conclusion: The study revealed that participants’ knowledge of preventing diabetic foot was high. However, the practice was poor. Therefore, there is a need for more health education on the practices that would emphasize diabetes management among diabetes patients.
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Open Access May 06, 2023

Socioeconomic Drivers of Conservation Commitment: Residents’ Willingness to Pay for Ecosystem Services Provided by Beaches in Lagos State, Nigeria

Abstract Beaches are known for their ability to provide people with several services – these are generally referred to as ‘ecosystem services’ and they have been identified as one of the ways through which nature relates to humans. However, beaches in Nigeria are challenged by mismanagement caused by anthropogenic factors. It is expected that people will demonstrate a certain amount of dedication to [...] Read more.
Beaches are known for their ability to provide people with several services – these are generally referred to as ‘ecosystem services’ and they have been identified as one of the ways through which nature relates to humans. However, beaches in Nigeria are challenged by mismanagement caused by anthropogenic factors. It is expected that people will demonstrate a certain amount of dedication to protecting this ecosystem to address this issue. Sometimes, a person's commitment to conservation is based on the advantages they anticipate or are currently experiencing from the ecosystem, which are a result of their socioeconomic traits. Against this backdrop, this study captured individuals’ commitment as their Willingness to Pay (WTP) for these ecosystem services, assessed their level of awareness of the various ecosystem services provided by beaches and investigated the impact of socioeconomic factors on participants’ willingness to pay. Data were collected using a structured questionnaire and a total of 221 responses were analyzed using descriptive statistics, logistic regression and content analysis. The results revealed that the cultural service provided by beaches was the most common ecosystem service identified by the participants. Furthermore, most of the participants were willing to pay less than $3 for beach maintenance while the major determinants of WTP were age, household size and education. This study recommended that the government should work with other stakeholders to set up programs that would boost people’s awareness of ecosystem services provided by beaches as well as reiterate the need to maintain this ecosystem to ensure continued enjoyment of the services provided.
Article
Open Access April 27, 2023

Evaluation of the Critical risk factors in PPP - procured Mass Housing Projects in Abuja Nigeria - A fuzzy synthetic evaluation (FSE) approach

Abstract The study accessed the critical risk factors in public-private partnership (PPP)-procured mass housing project (MHP) delivery in Nigeria. The research design adopts a quantitative approach, using well-structured questionnaires distributed to stakeholders involved in PPP-MHPs i.e. consultants, in-house professionals, contractors, and the organized private sector (OPS) registered with PPP [...] Read more.
The study accessed the critical risk factors in public-private partnership (PPP)-procured mass housing project (MHP) delivery in Nigeria. The research design adopts a quantitative approach, using well-structured questionnaires distributed to stakeholders involved in PPP-MHPs i.e. consultants, in-house professionals, contractors, and the organized private sector (OPS) registered with PPP departments in the Federal Capital Territory Development Authority (FCDA) Abuja, Nigeria. The instrument relates to the background information of respondents and the risk peculiar to PPP-MHP. Sixty-three (63) risk factors were submitted for the respondents to rank using Mean Item score (MIS) for risk occurrence and its severity, while risk significance index (RI) was used to determine the risk impact. Fuzzy Synthetic Evaluation (FSE) method was subsequently applied to determine the risk criticality groups and the overall risk level in the sector. The fuzzy set theory deals with ambiguous, subjective and imprecise judgments peculiar to decision making in construction project risk assessment. It aims to provide a synthetic evaluation of an object relative to a fuzzy decision environment with multiple criteria that requires qualitative linguistic terms. The findings show that thirty-one (31) risk factors were critical in the sector while financial and micro-economic risk group is contributing most significantly to the overall risk level in PPP-MHPs in Nigeria. The top 10 risk factors in the sector include availability of finance, high finance cost, the unstable value of the local currency, lack of creditworthiness, influential economic events (boom/recession), high bidding cost, poor financial market, financial attraction to project investors, interest rate volatility, inflation rate volatility, corruption and lack of respect for the law, non-involvement of the host community and poor execution of housing policies. The implication for practice is that having known the risk group contributing most significantly to the overall risk level in PPP-MHPs, adequate financial and budgetary allocation should be made available before embarking on such venture so as to sustain the scheme in the country. The study is one of the recent researches conducted on housing, since the procurement option is novel in the sector. The study is of immense value to PPP actors in providing necessary information required to formulate risk response methods in minimize the identified risk impact sector.
Article
Open Access January 14, 2023

Searching for What You Can’t See - Evaluation of Pesticide Residues in Grain Sold at Selected Markets of Southwest Nigeria

Abstract Studies on the use of pesticides in southwest Nigeria have revealed a substantial rise in a variety of pesticide-related illnesses, including mental impairment and reproductive problems. Those who work in agriculture and are regularly exposed to pesticides are the most impacted. The World Health Organization (WHO) predicts that three million severe pesticide poisoning episodes occur globally each [...] Read more.
Studies on the use of pesticides in southwest Nigeria have revealed a substantial rise in a variety of pesticide-related illnesses, including mental impairment and reproductive problems. Those who work in agriculture and are regularly exposed to pesticides are the most impacted. The World Health Organization (WHO) predicts that three million severe pesticide poisoning episodes occur globally each year, with at least 300.000 deaths and 99% of cases occurring in low- and middle-income nations. The effects of longer-term exposure to pesticides on health are not yet precisely estimated. Objectives: To this end, the objective of this study is to assess the knowledge of pesticide residues and common pesticides in grain-based food (brown and white beans, yellow and white maize, brown millet and rice) about pesticide use in selected markets of Southwest Nigeria. Methods: A total of 240 respondents were selected from four states (Ado-Ekiti, Ibadan, Osun and Ondo) with the aid of structured questionnaire and interview guide using purposive sampling technique. The markets were Oja-titun (market) Ile-Ife, Osun; Alesinloye Market Ibadan, Oyo; Oja Oba, Ado-Ekiti, Ekiti; and Oja Oba, Akure Ondo State. The identification and quantification of pesticide residues was done using a Varian 3800/4000 gas chromatograph mass spectrometer while 60 structured questionnaires were administered to respondents including food merchants, buyers/consumers as well as food vendors. Data were analysed using descriptive statistics. Results: The experiment was conducted from November 2020 to November 2021. Up to 50.4% never read instructions on pesticide application while a shared 24.8% read them always and occasionally. The number of respondents who never read the instructions were particularly high in Ekiti and Ondo, up to 52.5% of the respondents in Ekiti do not know whether or not they are exposed to pesticides during application. Also, majority of the respondents never attended any professional training on pesticide application, this amounted to 79.3%. Most people were not aware that unsafe pesticide application is harmful to human health. Similarly, a wide variety of symptoms were reported by respondents following pesticide application or consumption of grains, these included headaches and dizziness, itching and redness of the eyes, skin allergy, diarrhea, and stomach disorder, vomiting and loss of appetite, weakness of the body, asthma, permanent skin patches, shortness of breath, excessive sweating. Millet recorded the highest number of OCP residues while maize had the lowest. On the contrary, maize had the highest number of OPP and carbamate residues while millet had the lowest number of OPP residues. Meanwhile, maize, rice and beans had only one carbamate pesticide residue. Conclusions: According to the study's conclusions, farmers who can only get information from agricultural extension officials should receive urgent and immediate attention for raising awareness. Additionally, extensive IPM training programs must be created with the intention of disseminating precautions for protecting human health and a healthy agro-ecosystem. In order to find more effective pest management methods that utilize less pesticides, it is crucial to reevaluate the pesticide residues and common pesticides found in grains in the targeted markets. To reduce farmers' exposure to pesticides, it is also required to establish personal protective measures, special educational initiatives, and legislation promoting the use of safer pesticides. Significance and novelty: This study gives policymakers a comprehensive understanding of the ways that may be utilized to close the significant knowledge gap on pesticide residues in grains and provides an insight into the knowledge of pesticide residues and common pesticides in grains.
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Open Access November 30, 2022

A Review of Application of LiDAR and Geospatial Modeling for Detection of Buildings Using Artificial Intelligence Approaches

Abstract Today, the presentation of a three-dimensional model of real-world features is very important and widely used and has attracted the attention of researchers in various fields, including surveying and spatial information systems, and those interested in the three-dimensional reconstruction of buildings. The building is the key part of the information in a three-dimensional city model, so extracting [...] Read more.
Today, the presentation of a three-dimensional model of real-world features is very important and widely used and has attracted the attention of researchers in various fields, including surveying and spatial information systems, and those interested in the three-dimensional reconstruction of buildings. The building is the key part of the information in a three-dimensional city model, so extracting and modeling buildings from remote sensing data is an important step in building a digital model of a city. LiDAR technology due to its ability to map in all three modes of one-dimensional, two-dimensional, and three-dimensional is a suitable solution to provide hyperspectral and comprehensive images of the building in an urban environment. In this review article, a comprehensive review of the methods used in identifying buildings from the past to the present and appropriate solutions for the future is discussed.
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Review Article
Open Access October 29, 2022

Patient Perspectives on Factors Influencing Initiation of Gynecologic Care

Abstract Addressing adolescent and sexual reproductive healthcare is essential to providing young patients with the resources they need to navigate and empower themselves with. However, there is limited data about how often this occurs. Several studies have previously indicated that there is a large gap in accessing this gap in low-income neighborhoods. Our study aims to identify the establishment of [...] Read more.
Addressing adolescent and sexual reproductive healthcare is essential to providing young patients with the resources they need to navigate and empower themselves with. However, there is limited data about how often this occurs. Several studies have previously indicated that there is a large gap in accessing this gap in low-income neighborhoods. Our study aims to identify the establishment of gynecologic care among adolescent cisgender women and elucidate potential reasons for seeking or not seeking out care. We approached women in the pediatric emergency room that matched the inclusion criteria set out. Qualitative surveys were conducted until thematic saturation was reached and a cross-section study design was employed. Interviews were analyzed through modified ground theory. The study was conducted at the pediatric emergency department at University Hospital located in Newark, NJ. In 2018 estimates, the Newark population consists of 47.0% Black and 39.2% Hispanic or Latinos. Semi-structured interviews were conducted with 27 cisgendered, English-speaking females between ages 18 to 25 presenting to the pediatric emergency room who may or may not have previously established primary care with a gynecologist. Transcriptions were analyzed using modified grounded theory and themes were identified using inductive coding of patient interviews.
Article
Open Access February 13, 2026

Integrated GIS and geotechnical assessment of the stability of the Oued Ayda dike (Kesra Siliana, Tunisia)

Abstract This study proposes an integrated approach combining geographic information systems (GIS) and geotechnical analyses to assess the stability of the Oued Ayda mountain lake dam, located in the Siliana Governorate, northwestern Tunisia. The mechanical properties of the embankment and foundation materials were integrated into a Mohr-Coulomb geomechanical model, while the pore water pressure [...] Read more.
This study proposes an integrated approach combining geographic information systems (GIS) and geotechnical analyses to assess the stability of the Oued Ayda mountain lake dam, located in the Siliana Governorate, northwestern Tunisia. The mechanical properties of the embankment and foundation materials were integrated into a Mohr-Coulomb geomechanical model, while the pore water pressure distribution was simulated for various representative hydromechanical scenarios: end of construction, normal operation, rapid drainage, and short- and long-term empty reservoir conditions. The stability analysis, performed using the Morgenstern-Price method with the SLOPE/W software (GeoStudio), reveals high safety factors on the upstream side (SF > 3 in the short term and SF ≥ 2 in the long term), indicating good resistance of this slope to hydraulic and mechanical stresses. Conversely, the results show that the downstream slope exhibits significantly lower safety factors, ranging from 1.335 to 1.338 under long-term conditions, particularly during normal operating and rapid drainage scenarios. These reduced values indicate a high vulnerability of this slope to persistent saturation and adverse hydraulic gradients. In conclusion, although the dam exhibits satisfactory overall stability, the downstream slope remains the most vulnerable area of the structure. The results underscore the need for rigorous management of water level fluctuations and suggest reinforcing the drainage system or implementing targeted stabilization measures to ensure the long-term safety and durability of the structure.
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Open Access January 19, 2026

Mature Cataract, A Veil Concealing, A Pachychoroid Spectrum: About Two Cases

Abstract The pachychoroid spectrum is a new entity grouping pathologies with common choroidal features. First described in 2013 by American ophthalmologist Bailey Freund and his team [1]. It is defined by a diffuse or focal increase in choroidal thickness with dilatation of choroidal vessels adjacent to Bruch's membrane, associated with retinal pigment epithelial dysfunction, loss of the choriocapillaris [...] Read more.
The pachychoroid spectrum is a new entity grouping pathologies with common choroidal features. First described in 2013 by American ophthalmologist Bailey Freund and his team [1]. It is defined by a diffuse or focal increase in choroidal thickness with dilatation of choroidal vessels adjacent to Bruch's membrane, associated with retinal pigment epithelial dysfunction, loss of the choriocapillaris and thinning of Sattler's layer [1, 2]. At present, the pachychoroid spectrum includes well-known pathologies such as central serous chorioretinitis (CSCR) and polypoidal choroidal vasculopathy (PCV), as well as pathologies of more recent description such as epitheliopathy or type 1 neovessels secondary to pachychoroid, pachydrusen, choroidal excavation and peripapillary pachychoroid. The morphological changes of the lens which is a cataract can be unilateral or bilateral and occur symmetrically or not over variable durations. A cataract is said to be mature when the opacification occupies the entire lens, it induces a complete loss of vision. It makes the visualization of the fundus reflection impossible, which explains the impossibility of visualizing hemorrhages and other lesions of the eye with the possibility of concealing a pachychoroid spectrum during the ocular examination in patients. The aim of our study is to describe the symptomatology and therapeutic approach of SPC.
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Case Report
Open Access November 09, 2025

Application of Building Information Modelling (BIM) for Enhancing Safety and Environmental Performance on Construction Sites in Nigeria

Abstract Background: Building Information Modelling (BIM) improves safety planning in construction by enabling visualization and simulation to identify and reduce risks. However, its adoption in Nigeria is limited. This study examines the application of BIM in enhancing safety and environmental performance on construction sites in Nigeria. Methodology: A quantitative cross-sectional survey [...] Read more.
Background: Building Information Modelling (BIM) improves safety planning in construction by enabling visualization and simulation to identify and reduce risks. However, its adoption in Nigeria is limited. This study examines the application of BIM in enhancing safety and environmental performance on construction sites in Nigeria. Methodology: A quantitative cross-sectional survey was conducted using a structured online questionnaire distributed to professionals in Nigeria’s construction industry. A purposive sampling method was employed to target respondents with relevant BIM experience. Data were analysed using SPSS version 28, applying descriptive statistics, chi-square tests, and logistic regression at a 5% significance level. Result: Findings show that BIM was fully adopted by 7.0% of organizations, with only 19.8% of respondents using it to identify safety hazards during planning. While 76.8% reported no notable safety benefit, 19.5% identified improved risk management as the key benefit. Most respondents (80.2%) reported no noticeable environmental benefits. Among those who did, improved energy efficiency was the most cited benefit (16.4%). Respondents with 10 or more years of experience were significantly more likely to report enhanced safety and environmental outcomes (AOR = 4.555; p = 0.003) and adequate BIM utilization (AOR = 3.255; p = 0.023). Those with intermediate BIM experience were also more likely to report high enhancement (AOR = 2.857; p = 0.039) and effective tool use (AOR = 2.881; p = 0.050). Conclusion: This study revealed that BIM has the potential to improve construction outcomes in Nigeria if supported by training, experience, and structured implementation.
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Open Access November 06, 2025

Ventral Attention Network Resting State Functional Connectivity: Psychosocial Correlates among US Adolescents

Abstract Background: Resting-state functional MRI (rsfMRI) provides insights into large-scale brain network organization associated with cognitive control, emotion regulation, and attentional processes. The ventral attention network (VAN) is a key salience-driven network that supports attentional re-orienting to behaviorally relevant stimuli. However, little is known about how VAN [...] Read more.
Background: Resting-state functional MRI (rsfMRI) provides insights into large-scale brain network organization associated with cognitive control, emotion regulation, and attentional processes. The ventral attention network (VAN) is a key salience-driven network that supports attentional re-orienting to behaviorally relevant stimuli. However, little is known about how VAN resting state functional connectivity varies by demographic, socioeconomic, psychosocial, and behavioral factors during early adolescence. Objective: To examine associations between VAN rsfMRI connectivity and multiple demographic, socioeconomic, psychosocial, and behavioral characteristics. Methods: Data came from the baseline and early follow-up waves of the Adolescent Brain Cognitive Development (ABCD) Study. The analytic sample included youth with high-quality baseline rsfMRI data and complete socioeconomic and psychosocial measures. The primary outcome was mean resting-state functional connectivity within the VAN across subcortical and cortical regions of interest (ROIs). Bivariate correlations were computed between VAN connectivity and demographic (age, sex, puberty, race/ethnicity), socioeconomic (income, parental education, marital status, neighborhood income), psychosocial (trauma, discrimination, financial difficulty), trait (impulsivity), and behavioral variables (body mass index, depression, suicide, prodromal symptoms, and substance use). Unadjusted bivariate correlations and adjusted logistic regressions were used for data analysis. Results: VAN connectivity showed small but significant correlations with multiple contextual factors. Higher household income, parental education, and neighborhood affluence were associated with greater connectivity, whereas Black race and Hispanic ethnicity were related to lower connectivity. Youth reporting higher discrimination and financial difficulty exhibited weaker VAN connectivity. Greater VAN connectivity was negatively associated with impulsive reward-driven trait (drive), prodromal symptoms, BMI, and marijuana and alcohol use. Associations between VAN connectivity and suicide, depression, marijuana use, and alcohol use remained significant in age and sex adjusted models. Conclusions: VAN connectivity reflects subtle neural correlates of socioeconomic and psychosocial context in early adolescence. Our results underscore the importance of integrating structural and contextual factors in interpreting brain-behavior associations across diverse populations. These findings are suggestive of stable socioeconomic and psychosocial correlates of network efficiency.
Article
Open Access October 29, 2025

Mean Diffusivity of the Left Caudal Anterior Cingulate Cortex and Past Major Depressive Disorder in Adolescents: Evidence from the ABCD Study

Abstract Background: Adolescence is a critical developmental stage for the emergence of major depressive disorder (MDD). Structural and diffusion neuroimaging studies have highlighted the anterior cingulate cortex (ACC) as a key region implicated in emotion regulation, stress reactivity, and mood processing. However, few studies have examined whether microstructural characteristics of the ACC, [...] Read more.
Background: Adolescence is a critical developmental stage for the emergence of major depressive disorder (MDD). Structural and diffusion neuroimaging studies have highlighted the anterior cingulate cortex (ACC) as a key region implicated in emotion regulation, stress reactivity, and mood processing. However, few studies have examined whether microstructural characteristics of the ACC, reflected by mean diffusivity (MD) within gray matter–white matter (GM–WM) contrast regions, are associated with depression in early adolescence. Objective: To examine whether mean diffusivity (MD) within the GM–WM contrast of the left caudal anterior cingulate cortex (ACC) is associated with a past diagnosis of MDD among adolescents in the Adolescent Brain Cognitive Development (ABCD) Study, after accounting for demographic, socioeconomic, and adversity-related factors. Methods: Data were drawn from adolescents with diffusion MRI–derived mean diffusivity measures and diagnostics. The independent variable was mean diffusivity (MD) of the GM–WM contrast in the left caudal ACC. The primary outcome was past MDD diagnosis based on structured psychiatric assessments. Covariates included age, sex, socioeconomic status (SES), and exposure to adverse childhood experiences (ACEs). Logistic regression models tested the association between ACC MD and past MDD. A secondary model evaluated the relationship between ACC MD and past suicide attempt. Results: Mean diffusivity of the left caudal ACC was associated with the odds of past MDD, independent of age, sex, SES, and adversity exposure. In contrast, ACC mean diffusivity was not associated with a history of suicide attempt. Conclusions: Increased mean diffusivity in the caudal ACC may indicate microstructural alterations associated with depressive vulnerability in adolescence. ACC tissue integrity may serve as a sensitive neural correlate of early-onset depression.
Article
Open Access October 04, 2025

Unequal Burden of Loss of a Loved One in Non-Hispanic Black and White Californians

Abstract Purpose: Although the effect of loss of a loved one on depression is well established, very limited knowledge exists on racial differences in this effect. Aim: In the current study we compared Non-Hispanic White (NHW) and Non-Hispanic Black (NHB) Californians for the effects of loss of a loved one on depression in a representative sample of adults in California. Methods: This cross-sectional study used data from the Survey of California Adults on Serious Illness and End-of-Life 2019. Overall, 1603 people entered our study. We compared 901 (56.2%) NHB and 702 (43.8%) NHW adults (age 18 and older). Race/ethnicity, demographics (age and gender), socio-economic factors (education, income, employment, and marital status), religiosity, and health (self-rated health and number of chronic medical conditions), and depression were measured. To perform data analysis, we used logistic regression models. Results: In the pooled sample, loss of a loved one was not associated with self-reported depression, net of all covariates. Race, however, interacted with loss of a loved one on depression, suggesting a larger association for NHBs compared to NHWs. In race-specific models, loss of a loved one predicted depression for NHBs (OR = 1.54) but not NHWs (OR [...] Read more.
Purpose: Although the effect of loss of a loved one on depression is well established, very limited knowledge exists on racial differences in this effect. Aim: In the current study we compared Non-Hispanic White (NHW) and Non-Hispanic Black (NHB) Californians for the effects of loss of a loved one on depression in a representative sample of adults in California. Methods: This cross-sectional study used data from the Survey of California Adults on Serious Illness and End-of-Life 2019. Overall, 1603 people entered our study. We compared 901 (56.2%) NHB and 702 (43.8%) NHW adults (age 18 and older). Race/ethnicity, demographics (age and gender), socio-economic factors (education, income, employment, and marital status), religiosity, and health (self-rated health and number of chronic medical conditions), and depression were measured. To perform data analysis, we used logistic regression models. Results: In the pooled sample, loss of a loved one was not associated with self-reported depression, net of all covariates. Race, however, interacted with loss of a loved one on depression, suggesting a larger association for NHBs compared to NHWs. In race-specific models, loss of a loved one predicted depression for NHBs (OR = 1.54) but not NHWs (OR = 0.99). Conclusion: There are differences between NHBs and NHWs in the effect of loss of a loved one on depression. NHBs show a stronger association between loss of a loved one and depression than NHWs. This result is not in line with the NHB mental health paradox or with NHB resilience but is consistent with the notion that social relations may be more salient for NHBs than for NHWs.
Article
Open Access May 04, 2025

Educational Attainment Better Protects Non-Latino than Latino People Against Diabetes Mellitus

Abstract Background: High educational attainment is a well-recognized protective factor against health problems such as diabetes. However, the theory of Minorities' Diminished Returns (MDRs) suggests that this protective effect is weaker for ethnic minorities compared to non-Latino Whites. This diminished effect is thought to result from structural inequalities, such as lower-quality [...] Read more.
Background: High educational attainment is a well-recognized protective factor against health problems such as diabetes. However, the theory of Minorities' Diminished Returns (MDRs) suggests that this protective effect is weaker for ethnic minorities compared to non-Latino Whites. This diminished effect is thought to result from structural inequalities, such as lower-quality education and fewer occupational opportunities, faced by ethnic minorities. Objective: This study examined the protective effect of years of schooling—used as a proxy for educational attainment—on diabetes mellitus (DM), overall and by ethnicity. Based on the MDRs framework, we hypothesized that the protective effect of education would be weaker for Latino individuals compared to non-Latinos. Methods: Data were drawn from the 2012 wave of the Understanding America Study (UAS), a nationally representative, internet-based panel. The outcome of interest was self-reported doctor diagnosis of DM. Logistic regression models were used to assess the association between educational attainment and DM, with an interaction term to explore differences between Latino and non-Latino individuals. Models were adjusted for age, sex, employment, immigration status, and marital status. Findings were presented as adjusted odds ratios (OR), p-values, and 95% confidence intervals (CIs). Results: Higher educational attainment was associated with lower odds of DM in both Latino and non-Latino individuals (p < 0.001). An interaction between education and ethnicity (p < 0.05) indicated that the protective effect of education was weaker for Latino individuals compared to non-Latinos. Conclusion: The findings align with the MDRs framework, which suggests that the health benefits of education are not equally distributed across ethnic groups. For Latino individuals, structural barriers such as lower educational quality and labor market discrimination may limit the protective effect of education against DM. While education is a key determinant of health, its unequal returns contribute to ethnic health disparities. Policymakers must address structural inequalities in education and employment that disproportionately affect ethnic minorities. Tackling these disparities through multi-sector policy interventions will require bipartisan political support.
Article
Open Access March 09, 2025

Place-Based Diminished Returns of Parental Education on Adolescents’ Inhalant Use in Rural Areas

Abstract Background Adolescent substance use is often influenced by socioeconomic and geographical factors. While higher parental education is typically associated with lower substance use, these protective effects may be weaker for marginalized groups facing structural disadvantages that limit the utility and returns of their economic and social resources. Rural areas, characterized by fewer [...] Read more.
Background Adolescent substance use is often influenced by socioeconomic and geographical factors. While higher parental education is typically associated with lower substance use, these protective effects may be weaker for marginalized groups facing structural disadvantages that limit the utility and returns of their economic and social resources. Rural areas, characterized by fewer employment opportunities and limited recreational activities, may contribute to marginalization-related diminished returns (MDRs) of parental education on adolescent substance use, including inhalant use. Objectives This study applies the MDRs framework to examine whether the protective effect of higher parental education on current inhalant use (past 30 days) among 12th-grade American adolescents varies by geographic location. Specifically, we assess whether youth from highly educated families in rural areas are at a disproportionate risk of inhalant use compared to their urban and suburban peers. Methods Using data from the 2024 Monitoring the Future (MTF) study, a nationally representative survey of 12th-grade adolescents in the U.S., we tested main effects and statistical interactions between parental education and residence (rural vs. urban/suburban) in predicting the odds of inhalant use over the past 30 days. Logistic regression models, both with and without interaction terms, were applied to evaluate whether the protective effects of parental education varied by residence location, controlling for relevant demographic and socioeconomic factors. Results Findings indicate a significant interaction between parental education and rural residence. While higher parental education was associated with lower odds of inhalant use in urban and suburban areas, this protective effect was substantially weaker in rural settings. Adolescents from highly educated families in rural areas exhibited a higher-than-expected risk of inhalant use, suggesting that geographic marginalization attenuates the benefits of parental socioeconomic resources. Conclusions These results highlight the role of place-based marginalization in shaping adolescent substance use disparities, demonstrating that MDRs extend beyond race and ethnicity to location-based disadvantages. Rural youths from highly educated families may face unique structural and social challenges that counteract the protective effects of parental education. Public health efforts should consider place-based interventions that address the economic, recreational, and social limitations of rural environments to reduce substance use risk among high-SES adolescents residing in rural areas.
Article
Open Access February 27, 2025

Hopelessness and Smoking among Black Adults

Abstract Background: While the link between depression and smoking is known, less is known about the relationship between hopelessness and smoking in large national community-based sample of Black people. Aims: This study investigates the association between hopelessness and smoking status, using data from the National Survey of American Life (NSAL), which is the only ethnically [...] Read more.
Background: While the link between depression and smoking is known, less is known about the relationship between hopelessness and smoking in large national community-based sample of Black people. Aims: This study investigates the association between hopelessness and smoking status, using data from the National Survey of American Life (NSAL), which is the only ethnically diverse nationally representative sample of Black adults. Methods: Data from the NSAL were analyzed. Hopelessness and smoking status were assessed using structured interviews. Logistic regression was employed to assess the link between hopelessness and smoking status, controlling for potential confounders such as demographic factors and socioeconomic indicators as well as depression. Results: 4,939 participants entered our analysis. Hopelessness was significantly associated with higher odds of smoking status. This association remained robust after adjusting for confounders such as demographic factors, socioeconomic status, and depression. Conclusions: Hopelessness may be a critical risk factor for smoking in Black adults. Promoting hope as a component of targeted tobacco cessation programs may help reduce tobacco use of Black populations.
Article
Open Access February 26, 2025

Innovations and Challenges in Pharmaceutical Supply Chain, Serialization and Regulatory Landscape

Abstract The pharmaceutical supply chain has become increasingly complex and vulnerable to various risks, including counterfeit drugs, diversion, and fraud. As these challenges threaten patient safety and the integrity of global healthcare systems, serialization has emerged as a pivotal innovation in pharmaceutical logistics and regulatory compliance. Serialization involves assigning unique identifiers to [...] Read more.
The pharmaceutical supply chain has become increasingly complex and vulnerable to various risks, including counterfeit drugs, diversion, and fraud. As these challenges threaten patient safety and the integrity of global healthcare systems, serialization has emerged as a pivotal innovation in pharmaceutical logistics and regulatory compliance. Serialization involves assigning unique identifiers to individual drug packages, enabling precise tracking and authentication at every stage of the supply chain. This process provides unprecedented transparency, enhances product security, and facilitates real-time monitoring of pharmaceutical products as they move from manufacturers to end consumers. Despite its potential to revolutionize pharmaceutical traceability, the integration of serialization technologies faces numerous obstacles. These include high implementation costs, regulatory inconsistencies across regions, and the technological challenges of managing vast amounts of data. Moreover, the complex, multi-tiered nature of the global supply chain introduces additional risks related to data integrity, cybersecurity, and interoperability between systems. As pharmaceutical companies seek to navigate these challenges, innovations in serialization technology—such as blockchain, artificial intelligence (AI), the Internet of Things (IoT), and radio frequency identification (RFID)—are providing promising solutions to enhance efficiency, reduce fraud, and increase visibility. This manuscript explores both the innovative advancements and the key challenges associated with the integration of serialization in the pharmaceutical supply chain. It delves into the evolving regulatory landscape, highlighting the need for global harmonization of serialization standards, and examines the impact of serialization on securing pharmaceutical distribution networks. Additionally, the paper emphasizes the importance of collaboration among manufacturers, technology providers, and regulatory bodies in overcoming implementation barriers and realizing the full potential of serialization. As the pharmaceutical industry moves towards a more interconnected and data-driven future, serialization promises to play a central role in shaping the next generation of drug safety and supply chain management. By addressing the hurdles to adoption and leveraging emerging technologies, the pharmaceutical sector can create a more secure, transparent, and efficient supply chain that better serves public health and fosters greater trust among consumers and healthcare professionals alike.
Review Article
Open Access February 19, 2025

The CEASE Tobacco Cessation Controlled Trial for Low-Income Racial and Ethnic Minority Participants: Key Predictors of Success

Abstract Background: Tobacco use remains disproportionately high among low-income and racial-ethnic minority populations. The CEASE program, with its self-help, hybrid/online, and in-person modalities, has demonstrated efficacy in promoting tobacco cessation. However, predictors of successful cessation among participants in these groups remain unclear. Objective: To identify baseline predictors of successful tobacco cessation among low-income and racial-ethnic minority participants in the CEASE program, with a focus on demographic, socioeconomic, behavioral, and psychosocial factors. Methods: Participants were allocated into three intervention arms: self-help, CEASE hybrid/online, and CEASE in-person. Baseline characteristics, including demographics (e.g., age, gender), socioeconomic status (e.g., education, employment), substance use profiles (e.g., cigarette packs per week, use of other tobacco products, menthol tobacco use), physical health (e.g., general health, number of cardiometabolic risk conditions), mental health (e.g., depressive symptoms, perceived stress), perceived social support, and nicotine dependence, were analyzed as potential predictors of cessation success. Multivariable logistic regression models were used to identify factors associated with successful quitting, controlling for the study arm. Results: In addition to the study arm, gender, baseline depression, cardiometabolic conditions, tobacco flavor, and the use of other tobacco products were significant predictors of quit success. Individuals receiving in-person interventions had significantly higher odds of quitting (AOR = 3.79, p < 0.05). Women were significantly less likely to quit compared to men (AOR = 0.24, p < 0.01). Participants with a greater number of cardiometabolic risk conditions were more likely to quit (AOR = 1.93, p < 0.05), while those with higher levels of depression had lower odds of quitting (AOR = 0.61, p < 0.05). Menthol tobacco users were also less likely to quit (AOR = 0.10, p < 0.05). Interestingly, individuals who used other forms of tobacco in addition to cigarettes had increased odds of quitting (AOR = 2.86, p [...] Read more.
Background: Tobacco use remains disproportionately high among low-income and racial-ethnic minority populations. The CEASE program, with its self-help, hybrid/online, and in-person modalities, has demonstrated efficacy in promoting tobacco cessation. However, predictors of successful cessation among participants in these groups remain unclear. Objective: To identify baseline predictors of successful tobacco cessation among low-income and racial-ethnic minority participants in the CEASE program, with a focus on demographic, socioeconomic, behavioral, and psychosocial factors. Methods: Participants were allocated into three intervention arms: self-help, CEASE hybrid/online, and CEASE in-person. Baseline characteristics, including demographics (e.g., age, gender), socioeconomic status (e.g., education, employment), substance use profiles (e.g., cigarette packs per week, use of other tobacco products, menthol tobacco use), physical health (e.g., general health, number of cardiometabolic risk conditions), mental health (e.g., depressive symptoms, perceived stress), perceived social support, and nicotine dependence, were analyzed as potential predictors of cessation success. Multivariable logistic regression models were used to identify factors associated with successful quitting, controlling for the study arm. Results: In addition to the study arm, gender, baseline depression, cardiometabolic conditions, tobacco flavor, and the use of other tobacco products were significant predictors of quit success. Individuals receiving in-person interventions had significantly higher odds of quitting (AOR = 3.79, p < 0.05). Women were significantly less likely to quit compared to men (AOR = 0.24, p < 0.01). Participants with a greater number of cardiometabolic risk conditions were more likely to quit (AOR = 1.93, p < 0.05), while those with higher levels of depression had lower odds of quitting (AOR = 0.61, p < 0.05). Menthol tobacco users were also less likely to quit (AOR = 0.10, p < 0.05). Interestingly, individuals who used other forms of tobacco in addition to cigarettes had increased odds of quitting (AOR = 2.86, p < 0.05). No other factors, including demographic variables (e.g., age), socioeconomic status (e.g., education, marital status), substance use profiles (e.g., cigarette packs per week, NRT use), or nicotine dependence, were significant predictors of cessation success. Conclusion: Baseline self-reported anxiety/depression and depressive symptoms play a critical role in reducing the likelihood of successful tobacco cessation among low-income and racial-ethnic minority participants in the CEASE program. These findings underscore the importance of addressing mental health challenges as part of tobacco cessation interventions to enhance their efficacy. Future research should explore targeted strategies for integrating mental health support into cessation programs to improve outcomes for underserved populations.
Article
Open Access February 10, 2025

Higher-than Expected Social Security Reliance Among Educated Black Americans: Minorities' Diminished Returns in National Health Interview Survey (NHIS) 2023

Abstract Background: While educational attainment is generally associated with reduced reliance on Social Security and disability benefits, Minorities' Diminished Returns (MDRs) theory suggests that the socioeconomic benefits of educational attainment are not equally distributed across racial groups and are weaker for minoritized populations. This study explores the association between educational [...] Read more.
Background: While educational attainment is generally associated with reduced reliance on Social Security and disability benefits, Minorities' Diminished Returns (MDRs) theory suggests that the socioeconomic benefits of educational attainment are not equally distributed across racial groups and are weaker for minoritized populations. This study explores the association between educational attainment and reliance on Social Security and disability benefits among Black and White adults in the United States. Objective: Building on the MDRs framework, we analyzed data from the National Health Interview Survey (NHIS) 2023 to examine how educational attainment impacts reliance on Social Security disability income, disability benefits, and public assistance for Black and White adults. Methods: We used a nationally representative sample of Black and White adults from the NHIS 2023 dataset. The outcomes assessed were reliance on three income sources: (1) Social Security disability income, (2) disability benefit income, and (3) public assistance disability income. Educational attainment was classified into three levels: less than high school (reference), high school diploma to some college, and college graduate or more. Logistic regression models assessed the relationship between educational attainment and reliance on each income source, with separate analyses for Black and White adults to evaluate differential effects. Results: Higher levels of educational attainment (high school diploma to some college and college graduate or more) were associated with lower odds of relying on Social Security disability, disability benefits, and public assistance. However, the protective effects of educational attainment were notably stronger for White adults than for Black adults. Among Black adults, even high educational attainment showed limited effectiveness in reducing reliance on these income sources, underscoring the Minorities' Diminished Returns (MDRs) phenomenon. Conclusions: Although educational attainment reduces reliance on Social Security and disability-related income sources, these protective effects are less pronounced for Black adults compared to White adults. The findings reveal persistent racial disparities in the economic returns of education, suggesting that structural factors may undermine the socioeconomic and health benefits of educational achievement for Black Americans. Targeted policy interventions may be needed to improve economic stability for Black adults, including those with higher educational credentials.
Article
Open Access February 10, 2025

Diminished Returns of Educational Attainment on Welfare Receipt of American Indian/Alaska Native People: National Health Interview Survey (NHIS) 2023

Abstract Background: Educational attainment is generally associated with reduced reliance on Social Security and disability benefits; however, the Minorities' Diminished Returns (MDRs) theory suggests that the socioeconomic benefits of education are weaker for minoritized populations. This study investigates the relationship between educational attainment and welfare receipt among American [...] Read more.
Background: Educational attainment is generally associated with reduced reliance on Social Security and disability benefits; however, the Minorities' Diminished Returns (MDRs) theory suggests that the socioeconomic benefits of education are weaker for minoritized populations. This study investigates the relationship between educational attainment and welfare receipt among American Indian/Alaska Native (AIAN) and White adults in the United States. Objective: Using the MDRs framework, we analyzed data from the National Health Interview Survey (NHIS) 2023 to examine how educational attainment impacts welfare receipt among AIAN and White adults. Methods: We analyzed a nationally representative sample of AIAN and White adults from the NHIS 2023 dataset. Welfare receipt was assessed as the receipt of any public assistance or welfare payments from state or local welfare offices. Educational attainment was categorized into three levels: less than high school (reference), high school diploma to some college, and college degree or higher. Logistic regression models were used to assess the relationship between educational attainment and welfare receipt, with separate analyses for AIAN and White adults to evaluate differential effects. Results: Higher educational attainment (high school diploma to some college and college degree or higher) was associated with lower odds of welfare receipt across both groups. However, the protective effect of a college degree was significantly weaker for AIAN adults compared to White adults. Consequently, AIAN adults remain at a higher risk of welfare reliance even with higher education, consistent with the Minorities' Diminished Returns (MDRs) framework. Conclusions: Although educational attainment generally reduces welfare reliance, this protection is less pronounced for AIAN adults than for White adults. This discrepancy suggests that structural factors, segregation, and social stratification may undermine the economic and health benefits of education for racialized groups in the U.S. Addressing these disparities requires policy interventions that extend beyond education, emphasizing quality job opportunities, healthcare access, and reduced labor market discrimination for individuals with advanced educational credentials, regardless of race.
Article
Open Access January 23, 2025

Weaker Effects of Educational Attainment on Chronic Medical Conditions in American Indian Alaska Native, Black, and Latino Adults: National Health Interview Survey 2023

Abstract Background: Chronic medical conditions are major drivers of healthcare spending, morbidity, and mortality in the United States, as well as critical indicators of health disparities. The disproportionately high rates of chronic medical conditions among Black, Latino, and American Indian and Alaska Native adults compared to non-Latino Whites highlight the urgent need to examine the factors [...] Read more.
Background: Chronic medical conditions are major drivers of healthcare spending, morbidity, and mortality in the United States, as well as critical indicators of health disparities. The disproportionately high rates of chronic medical conditions among Black, Latino, and American Indian and Alaska Native adults compared to non-Latino Whites highlight the urgent need to examine the factors contributing to these disparities. While higher socioeconomic status is generally associated with better health outcomes, this benefit may be diminished for racialized and minoritized populations. Objective: This study investigates the protective effects of educational attainment and income-to-poverty ratio on the prevalence of chronic medical conditions and examines whether these effects vary across racial and ethnic groups, specifically among Black, Latino, and American Indian and Alaska Native adults compared to non-Latino White adults. Methods: Using data from the 2023 National Health Interview Survey (NHIS), this cross-sectional study analyzed the association between educational attainment and chronic medical conditions across racial and ethnic groups. Logistic regression models were employed to assess whether the strength of the relationship between education and chronic medical conditions differed by racial/ethnic group, controlling for key demographic and socioeconomic covariates. Sample size was 29,373 which was reflective of 256,566,689 US population. Results: Consistent with the theory of Minorities' Diminished Returns, findings showed that the protective effects of higher educational attainment on chronic medical conditions were significantly weaker for Black, Latino, and American Indian and Alaska Native adults than for their non-Latino White counterparts. Even among individuals with higher education, Black, Latino, and American Indian and Alaska Native adults faced elevated risks of chronic medical conditions. Conclusion: While educational attainment generally reduces the prevalence of chronic medical conditions, this protective effect is moderated by racial and ethnic background. Structural barriers limit the health benefits of educational attainment. This underscores the need for policies that address structural inequities—such as low-quality education and occupational segregation—that constrain the protective health effects of educational attainment for minoritized groups.
Article
Open Access January 23, 2025

Diminished Returns of Educational Attainment on Hypertension Prevalence among American Indian and Alaska Native Adults: National Health Interview Survey 2023

Abstract Background: Research on Minorities’ Diminished Returns (MDRs) consistently reveals that social determinants of health, especially educational attainment, do not yield equal health benefits across racial and ethnic groups in the United States. MDRs suggest that social stratification, segregation, lower education quality, and labor market discrimination contribute to diminished health returns [...] Read more.
Background: Research on Minorities’ Diminished Returns (MDRs) consistently reveals that social determinants of health, especially educational attainment, do not yield equal health benefits across racial and ethnic groups in the United States. MDRs suggest that social stratification, segregation, lower education quality, and labor market discrimination contribute to diminished health returns of education among minoritized groups. However, few studies have tested the relevance of MDRs in American Indian and Alaska Native (AIAN) populations compared to non-Hispanic White adults. Objectives: This study aimed to examine the strength of the inverse association between educational attainment and hypertension prevalence, hypothesizing that the protective effect of education on hypertension risk is reduced among AIAN adults relative to non-Hispanic Whites. Methods: Using data from the 2023 National Health Interview Survey (NHIS), we analyzed a nationally representative sample of adults aged 18 and older. Logistic regression models examined the association between educational attainment and self-reported hypertension diagnosis, stratified by racial/ethnic group (AIAN vs. non-Hispanic White). Models were adjusted for key covariates, including age, gender, income, and insurance status. Results: Higher educational attainment was associated with a lower prevalence of hypertension in the combined sample of AIAN and non-Hispanic White adults. However, this protective association was significantly weaker among AIAN adults compared to non-Hispanic White adults, as evidenced by a significant interaction between race and education. Conclusion: AIAN adults exhibit a higher prevalence of hypertension even at higher levels of educational attainment compared to non-Hispanic White adults, supporting the relevance of MDRs for AIAN populations. This finding underscores the need for public health interventions that address structural barriers and contextual factors unique to AIAN populations. Policies focused solely on educational access may be insufficient to reduce hypertension risk among AIAN adults without addressing broader social and structural inequities.
Article
Open Access November 19, 2024

Social Epidemiology of Dual Use of Electronic and Combustible Cigarettes Among U.S. Adults: Insights from the Population Assessment of Tobacco and Health (PATH) Study

Abstract Background: The dual use of e-cigarettes and combustible cigarettes poses significant public health concerns due to the compounded risks associated with the use of both products. Understanding the predictors of dual use can inform targeted interventions and tobacco control strategies aimed at reducing nicotine dependence and health risks among adults. Objective: This study [...] Read more.
Background: The dual use of e-cigarettes and combustible cigarettes poses significant public health concerns due to the compounded risks associated with the use of both products. Understanding the predictors of dual use can inform targeted interventions and tobacco control strategies aimed at reducing nicotine dependence and health risks among adults. Objective: This study aims to identify the sociodemographic predictors of dual use of e-cigarettes and combustible cigarettes among U.S. adults using baseline data from the Population Assessment of Tobacco and Health (PATH) Study. Methods: We analyzed baseline data from the PATH Study, focusing on adult participants who reported the use of both e-cigarettes and combustible cigarettes. Logistic regression models were used to identify the associations between dual use and key sociodemographic variables, including age, gender, race/ethnicity, and education level. Results: The analysis revealed that dual use of e-cigarettes and combustible cigarettes was predominantly observed among young, female, non-Latino, White, and highly educated adults. Younger adults were more likely to engage in dual use compared to older age groups. Females showed higher rates of dual use compared to males. Non-Latino White individuals were more likely to be dual users than individuals from other racial/ethnic backgrounds. Additionally, higher educational attainment was associated with increased dual use, contrary to traditional smoking patterns. Conclusion: The findings highlight specific demographic groups that are at higher risk of dual use of e-cigarettes and combustible cigarettes, particularly younger, highly educated, non-Latino White females. These insights suggest the need for tailored public health interventions that address the unique needs and behaviors of these populations. Future research should explore the underlying motivations and contextual factors contributing to dual use to enhance the effectiveness of tobacco control policies and cessation programs.
Article
Open Access November 09, 2024

Educated but on Social Security Disability Insurance: Minorities’ Diminished Returns

Abstract Background: Educational attainment is widely regarded as a key predictor of economic and social outcomes in later life, including the likelihood of receiving Social Security Disability Insurance (SSDI). According to the Minorities' Diminished Returns (MDRs) theory, however, the benefits of education may be less pronounced for racial and ethnic minorities compared to non-Latino [...] Read more.
Background: Educational attainment is widely regarded as a key predictor of economic and social outcomes in later life, including the likelihood of receiving Social Security Disability Insurance (SSDI). According to the Minorities' Diminished Returns (MDRs) theory, however, the benefits of education may be less pronounced for racial and ethnic minorities compared to non-Latino Whites. This study investigates whether the effects of education on the likelihood of receiving SSDI differ by race and ethnicity, focusing on Black and Latino Americans. Objective: The primary aim of this study was to examine the relationship between educational attainment (measured in years of schooling) and the likelihood of receiving SSDI, with a specific focus on exploring how this relationship varies by race and ethnicity, in line with the MDRs framework. Methods: Data were drawn from the Understanding America Study (UAS), a nationally representative, internet-based panel survey. The sample included Black, Latino, and non-Latino White U.S. adults. Our sample size was 12,975 adults over the age of 18. Logistic regression models were used to assess the association between educational attainment and receiving SSDI, adjusting for demographic variables such as age, sex, employment status, and marital status. Interaction terms between race/ethnicity and educational attainment were included to explore whether the returns on education varied across racial and ethnic groups. Results: Higher educational attainment was significantly associated with a lower likelihood of receiving SSDI in the overall sample. However, consistent with the MDRs framework, the protective effect of education was significantly weaker for both Black and Latino individuals compared to non-Latino Whites. Black and Latino participants with similar levels of education as their non-Latino White counterparts were more likely to receive SSDI, reflecting diminished returns on educational attainment for these groups. Conclusion: This study provides strong evidence supporting the MDRs theory, demonstrating that the protective effects of education on the likelihood of receiving SSDI are not equally distributed across racial and ethnic groups. Black and Latino Americans experience weaker returns on their education when it comes to avoiding SSDI, likely due to structural inequalities and systemic barriers. These findings highlight the need for policies that address not only educational disparities but also the broader societal factors that limit the benefits of education for racial and ethnic minorities.
Article
Open Access August 07, 2024

Revolutionizing Active Pharmaceutical Ingredients: From Concept to Compliance

Abstract Active Pharmaceutical Ingredients (APIs) serve as the cornerstone of pharmaceutical development, driving therapeutic efficacy and safety in drug formulations. This article provides a comprehensive overview of the lifecycle of APIs, starting from their discovery and development, through to manufacturing processes and regulatory oversight. The development of APIs begins with intensive research and [...] Read more.
Active Pharmaceutical Ingredients (APIs) serve as the cornerstone of pharmaceutical development, driving therapeutic efficacy and safety in drug formulations. This article provides a comprehensive overview of the lifecycle of APIs, starting from their discovery and development, through to manufacturing processes and regulatory oversight. The development of APIs begins with intensive research and discovery efforts, where medicinal chemists and pharmacologists identify and optimize potential compounds through computational modelling, high-throughput screening, and structure-activity relationship studies. Promising candidates undergo rigorous preclinical testing to assess pharmacological properties, safety profiles, and potential adverse effects in animal models. Upon successful preclinical outcomes, APIs progress to clinical trials, involving phases of testing in human subjects to evaluate efficacy, dosage regimens, and safety profiles under controlled conditions. Clinical trial data are meticulously analyzed to support regulatory submissions, demonstrating the API's therapeutic benefits and safety for eventual patient use. Manufacturing APIs involves complex chemical synthesis or biotechnological methods, ensuring precise control over reaction conditions, purity, and yield. The scale-up from laboratory synthesis to industrial production demands adherence to Good Manufacturing Practices (GMP), where stringent quality control measures verify consistency, potency, and stability throughout production batches. Regulatory oversight by authorities such as the Food and Drug Administration (FDA) in the United States and the European Medicines Agency (EMA) in Europe ensures that APIs meet stringent standards of safety, efficacy, and quality before market approval. Manufacturers must submit comprehensive Chemistry, Manufacturing, and Controls (CMC) data, detailing manufacturing processes, analytical methods, and stability studies to support regulatory filings.
Review Article
Open Access October 30, 2024

Social Determinants of Successful Smoking Cessation: An Eight-Year Analysis of Population Assessment of Tobacco and Health (PATH) Data

Abstract Background: Smoking cessation is a crucial public health goal due to its substantial impact on reducing the morbidity and mortality associated with tobacco use. However, significant disparities in smoking cessation success persist across socioeconomic groups in the United States. Objectives: This study aimed to examine differences in smoking cessation rates among daily smokers [...] Read more.
Background: Smoking cessation is a crucial public health goal due to its substantial impact on reducing the morbidity and mortality associated with tobacco use. However, significant disparities in smoking cessation success persist across socioeconomic groups in the United States. Objectives: This study aimed to examine differences in smoking cessation rates among daily smokers based on race, ethnicity, and socioeconomic status (SES) using data from the Population Assessment of Tobacco and Health (PATH) study, spanning waves 1 to 6 (eight years). Methods: Longitudinal data from PATH were analyzed, focusing on baseline daily cigarette smokers followed over an eight-year period to assess cessation outcomes. SES was measured by education and poverty status. Successful smoking cessation was defined as sustained abstinence from cigarettes for 12 months or more at the final wave. Logistic regression models identified predictors of successful cessation, adjusting for potential confounders, including age, nicotine dependence, and access to cessation resources. Results: The analysis revealed significant disparities in cessation success across racial, ethnic, and SES groups. Smokers living in poverty and those with lower educational attainment were less likely to achieve cessation success than their counterparts. Race (Black) and ethnicity (Latino) were also significantly associated with lower cessation success. Conclusions: This study highlights the social determinants of smoking cessation success among U.S. adult smokers, with lower success rates observed among those in poverty and with less educational attainment. These findings emphasize the need for targeted interventions that address the unique barriers to cessation faced by low-SES groups. Public health strategies should prioritize equitable access to cessation resources and culturally tailored interventions to reduce these disparities and improve cessation outcomes among all smokers.
Article
Open Access October 26, 2024

Exploring the Relationship between Teacher Training and Challenges in Delivering Effective Sex Education

Abstract This study aimed to explore the relationship between teacher training and challenges in delivering effective sex education in the Sagnarigu district in the Northern region of Ghana. The Social-cultural theory underpins the study. A descriptive survey research design was adopted for the study. The population of this study comprises teachers, head teachers and a School Improvement Support Officer [...] Read more.
This study aimed to explore the relationship between teacher training and challenges in delivering effective sex education in the Sagnarigu district in the Northern region of Ghana. The Social-cultural theory underpins the study. A descriptive survey research design was adopted for the study. The population of this study comprises teachers, head teachers and a School Improvement Support Officer (SiSo) in basic schools in the Gumani/Nyanshegu circuit in the Sagnarigu district of the Northern Region. This study adopted multi-sampling methods to select respondents. Random and purposive sampling techniques were used to select the study's 10 basic schools and 83 respondents. The main tools used for the data collection were the questionnaire and interview. The data was analysed using Statistical Package for Social Scientists (SPSS) software version 23 tools. Descriptive Statistical tools such as frequencies were used to gauge the number of occurrences of the studied variables. The qualitative data was also further analysed in line with the research questions to establish patterns of similarities and variations. These were then validated with the quantitative data for any possible contradictions in the findings. The study concludes that people's socio-cultural and religious beliefs and practices affect the teaching of sex education in school. It was observed that sex education could be misconstrued as an encouragement to young people to engage in early sexual promiscuity. Finally, the study concludes that there cannot be effective sex education without the appropriate logistics such as T.L.M.s, syllabus and time allocation for the subject. The study also acknowledges that the availability of these materials must go along with appropriate capacity building for teachers to be well-positioned to teach the subject. It is recommended that Sexuality education should be included in the curricular and academic calendar of basic schools, along with the provision of adequate T.L.M.s and the proper collaboration with appropriate agencies for the effective teaching of the subject. Sex education needs to be given maximum attention, just as any of the life skills subjects, with adequate investment and motivation to both teachers and pupils to ensure a meaningful impact. There should be regular monitoring, supervision, and assessment of the training of teachers and its influence on the teaching of the subject, as well as ensuring that ethical considerations regarding cultural and religious sensitivities and individual privacy issues are upheld.
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Article
Open Access July 21, 2024

Securing Pharmaceutical Supply chain to Combat Active Pharmaceutical Ingredient Counterfeiting

Abstract Pharmaceutical Product serialization aims to assign distinct serial numbers to items within a pharmaceutical supply chain. However, this process faces several security challenges like Theft of valid serial numbers may occur, enabling the labelling of counterfeit products. Therefore, it's essential to ensure the uniqueness of serial numbers can be verified at any point in the product's lifecycle [...] Read more.
Pharmaceutical Product serialization aims to assign distinct serial numbers to items within a pharmaceutical supply chain. However, this process faces several security challenges like Theft of valid serial numbers may occur, enabling the labelling of counterfeit products. Therefore, it's essential to ensure the uniqueness of serial numbers can be verified at any point in the product's lifecycle within the supply chain. Intimidatory nodes along the distribution network could corrupt planned changes of custody for products. Ensuring verifiability of compliance with these changes is crucial. Manufacturers and consumers need assurance that perishable goods with expired shelf lives are appropriately discarded. In this paper, we review a product serialization method leveraging blockchain technology to address these security concerns within a multi-party perishable goods supply chain. Blockchains offer potential solutions by providing a secure platform for data sharing in multi-party environments, enhancing security and transparency. Within Blockchain technology, each distribution partner is registered to uphold transparency regarding drug information. The system facilitates real-time transfer of ownership changes, recording them as blocks with date and time stamps. This ensures visibility to all partners in real time, maintaining the authenticity of drugs. This article aims to outline how Blockchain technology benefits the pharmaceutical industry by enhancing traceability and trackability of drugs throughout the entire pharmaceutical supply chain.
Review Article
Open Access February 15, 2024

Influence of Televangelism on Ghanaian Women

Abstract The purpose of this study was to examine the influence of new religious movements’ televangelism on women in Dunkwa-on-Offin in the central region of Ghana. The study adopted the sequential explanatory mixed-methods approach. The study population was important because they make up a bigger share of individuals who attend mainline churches and are constantly exposed to televangelism in their daily [...] Read more.
The purpose of this study was to examine the influence of new religious movements’ televangelism on women in Dunkwa-on-Offin in the central region of Ghana. The study adopted the sequential explanatory mixed-methods approach. The study population was important because they make up a bigger share of individuals who attend mainline churches and are constantly exposed to televangelism in their daily lives. A multi-stage sampling technique (purposive and simple random sampling techniques) was used to select two hundred (200) women for the study. Krejcie and Morgan's table determined the two women population of 400 (for both churches). The main instruments for data collection were questionnaires and interview guides. Quantitative data was analysed with the use of the IBM SPSS statistics software version 23, to compute frequency distributions, percentages, tables and cross-tabulation. Descriptive statistics and inferential analysis were employed in the analysis of the data. Qualitative data was analyzed thematically by identifying relevant information, coding, classification and summaries. The study revealed that televangelism has influenced women to follow televangelists rather than the teachings of their churches. Also, the activity has influenced the youth and women to follow false teachings, prosperity and vain promises of travelling. The findings of the study revealed that televangelists’ messages are geared towards obtaining money and raising unrealistic hopes. It is recommended that the government should also establish and enforce policies and regulations that encourage genuine televangelism programming and deter televangelists who are driven by fraud and self-gain by registering all the churches and holding them accountable for their actions.
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Article
Open Access February 12, 2024

An Appraisal of PROCESS and REACH Model on Forgiveness, Anger and Depression among Adolescents in Junior High Schools in Nanumba North Municipality, Ghana

Abstract The purpose of the study was to examine the effect of REACH and Process Models on forgiveness, anger and depression among 11- to 19-year-old adolescents in junior high schools in Bimbilla in the Northern Region of Ghana. The study employed a mixed-method design. The population for the study comprised all junior high school students totalling 3632. Of this number, 1,888 (55%) of the students were [...] Read more.
The purpose of the study was to examine the effect of REACH and Process Models on forgiveness, anger and depression among 11- to 19-year-old adolescents in junior high schools in Bimbilla in the Northern Region of Ghana. The study employed a mixed-method design. The population for the study comprised all junior high school students totalling 3632. Of this number, 1,888 (55%) of the students were males, while 1744(45%) were females. The accessible population was 1,636 from eight (8) JHSs with 952(55%) of them being boys and the remaining 684(45%) being girls. The participants were selected based on their low levels of forgiveness and high levels of anger and depression determined by the Depression Mode Scale and Anger Self-Report. Purposive and simple random sampling techniques were used to select 60 participants for the study, with each group having 20 participants. The main instruments used for the study are questionnaires (Enright Forgiveness Inventory (EFI). Anger self-report questionnaire (ASR), and Depressed Mood Scale (DMS) and semi-structured interview guide. One-way Analysis of Covariance (ANCOVA) was used to test the hypotheses. The study indicates that both the REACH model and PROCESS model have the efficacy in enhancing forgiveness among adolescents. The study also revealed that the REACH model and Process model have efficacy in reducing levels of depression among adolescent students. It is recommended that Counselling Centres should be set up by District Education Offices and the District Assemblies in the community so that students can visit the centre anytime they feel hurt. Regular seminars, lectures and symposia should be organized regularly by Counsellors and Psychologists using the efficacy of forgiveness therapies (Process and REACH Therapies) for students to be sensitized on the need to patronise forgiveness interventions. It is also recommended that the Government should provide adequate funds and support to encourage the conduct of research in forgiveness counselling since it is a new concept in Africa and Ghana in particular.
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Article
Open Access January 19, 2024

Modelling Population Growth Prognosis

Abstract Logistic growth model and its variants have been adjudged to be the most appropriate model for forecasting human population. However, in this article, we estimated the carrying capacity of Abuja using the logistic model. Then, we presented the parameters used to ascertain that the logistic model has the best fit in modelling population growth of Abuja over time. Meanwhile, a population growth [...] Read more.
Logistic growth model and its variants have been adjudged to be the most appropriate model for forecasting human population. However, in this article, we estimated the carrying capacity of Abuja using the logistic model. Then, we presented the parameters used to ascertain that the logistic model has the best fit in modelling population growth of Abuja over time. Meanwhile, a population growth sensitivity analysis is presented for the year 1962 to 2200.The result shows that by the year 2050, Abuja population growth rate will be out of control, if nothing substantial is implemented. Similarly, from the year 2150, the results show that stability will return again. Furthermore, the result of the error analysis conducted on the logistic model shows that Abuja has a growing population and that logistic growth model with MAPE and RMSE values of 0.98% and 7,817.07 respectively is the most accurate. The study concludes that logistic growth model with R−squared value of 0.776 has the best fit for population growth projection of Abuja. With approximate growth rate at 9.3% per annum, the projected population of Abuja will hit 30,220,701 million by the year 2039 all things being equal. Therefore, we recommend that the government should invest in massive agricultural reforms to accommodate the growing population, expand Abuja by developing its suburbs, and engage in massive reorientation of the populace on the dangers of uncontrolled births and the education of the girl child.
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Article
Open Access November 01, 2023

Serialized Drug Traceability in the Supply Chain Using Distributed Ledger Technology

Abstract Currently, Drug Counterfeiting is the biggest challenge facing the pharmaceutical industry. They are encountering this threat due to high market demand for the drugs and their profit margin. The lack of data transparency and traceability also lured criminals into the counterfeiting of drugs which, is impacting people’s health and put their life in danger. Through the drug supply chain, a [...] Read more.
Currently, Drug Counterfeiting is the biggest challenge facing the pharmaceutical industry. They are encountering this threat due to high market demand for the drugs and their profit margin. The lack of data transparency and traceability also lured criminals into the counterfeiting of drugs which, is impacting people’s health and put their life in danger. Through the drug supply chain, a substantial portion of counterfeit drugs are injected and distributed through the healthcare supply chain network, so the supply chain plays a vital role in drug distribution and impacts patient lives. Through digitalization in the healthcare sector, Distributed Ledger Technology (DLT) provides a platform with ground-breaking results by providing a system for drug traceability with consideration of the critical requirements of transparency, privacy, and authenticity without involving any third party. In DLT, each distribution partner is registered to maintain transparency with the drug information. Real-time transfer of information about the change of ownership with date and time in the form of blocks gives visibility to all the partners in real time about the authenticity of drugs. This article will give information about the benefits of Distributed Ledger Technology to the pharmaceutical industry and the traceability of drugs from end-to-end of the pharmaceutical supply chain.
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Review Article
Open Access August 18, 2023

Barriers to Effective Solid Waste Management in Ghana: A Case of Komenda-Edina-Eguafo-Abrem Municipality

Abstract The objective of this study was to examine the barriers to effective solid waste management in the Komenda-Edina-Eguafo-Abrem Municipality in the Central Region of Ghana. This study adopted the cross-sectional descriptive survey research design. The population for the study comprised all residents of 18 years or older as well as waste management agencies in the KEEA Municipality. A simple random [...] Read more.
The objective of this study was to examine the barriers to effective solid waste management in the Komenda-Edina-Eguafo-Abrem Municipality in the Central Region of Ghana. This study adopted the cross-sectional descriptive survey research design. The population for the study comprised all residents of 18 years or older as well as waste management agencies in the KEEA Municipality. A simple random sampling technique was used to select 380 residents together with 45 staff of the Zoomlion Company Ltd in the KEEA Municipality for the study. The questionnaire was the main instrument used for the data collection. Frequencies, percentages, means and standard deviations were used to analyse the questionnaire items on the research questions. This was done with the use of the Statistical Package for Service Solutions (SPSS) version 21. There were a number of barriers to effective solid waste management practices. Some of the barriers were inadequate environmental education; inadequate logistics and funds; inadequate depots, skips and dustbins; lack of adequate skilled personnel to manage services efficiently; and apathetic attitude/inertia on the part of some of the residents. Some other barriers included: irregular collection of waste by waste management companies; lack of appropriate sites for waste disposal; unwillingness of some households to pay for the collection and appropriate disposal of solids; and refuse dumps located very far from home. It is recommended that the government through the Ministry of Local Government should provide adequate logistics and funds for the procurement of dustbins in order to ensure proper solid waste management. The Assembly should ensure that Zoomlion collects waste regularly. The Assembly should encourage residents to pay for the collection of waste and sanction recalcitrant residents who do not adhere to appropriate solid waste management practices.
Article
Open Access August 09, 2023

Anti-Cancer and Anti-Fungal Activities of Calotropis procera: a Narrative Review

Abstract Calotropis procera, a medicinally important plant found in Asia, was explored for its anticancer and antibacterial properties in this study. The leaves of C. procera were extracted using methanol and FTIR and UV-VIS spectrophotometry were used to characterize them. Using the MTT assay and the disc diffusion test, the extract was examined for anticancer activity against the MCF7 breast cancer cell [...] Read more.
Calotropis procera, a medicinally important plant found in Asia, was explored for its anticancer and antibacterial properties in this study. The leaves of C. procera were extracted using methanol and FTIR and UV-VIS spectrophotometry were used to characterize them. Using the MTT assay and the disc diffusion test, the extract was examined for anticancer activity against the MCF7 breast cancer cell line and antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). The methanolic fraction of C. procera was found to be efficient against the MCF7 cell line and dramatically suppressed MRSA growth. The metabolic fraction of C. procera leaves is important in suppressing the growth of the MCF7 cell line, and it has the potential to be an effective antibacterial agent, according to our findings. The implications of Calotropis procera for all healthcare professionals including oncologists, physicians, pharmacists, nurses, and nutritional therapists are significant. With the increasing incidence of cancer and antibiotic-resistant bacterial infections, there is a growing need for new, effective, and safer herbal treatments.
Review Article
Open Access May 15, 2023

Social Studies Teachers' Authentic Assessment Practices, Tools and Challenges in Assessing Students' Learning Outcomes

Abstract Assessment is a vital aspect of curriculum practice. The study adopted explanatory mixed-method approach and sequential research design. The population for the study comprised all Social Studies teachers in Junior High Schools in the Ayensuano District. Convenient sampling techniques and census method were used to select the district, and all the one hundred and twenty-seven (127) teachers who [...] Read more.
Assessment is a vital aspect of curriculum practice. The study adopted explanatory mixed-method approach and sequential research design. The population for the study comprised all Social Studies teachers in Junior High Schools in the Ayensuano District. Convenient sampling techniques and census method were used to select the district, and all the one hundred and twenty-seven (127) teachers who teach Social Studies in the junior high schools in the district. The main instruments used for data collection and analysis were questionnaire and interview guide. The quantitative data was analysed both descriptive and inferential statistical tools. The qualitative data was transliterated and coded based on themes. Pre-set themes were used to generate the transcript (text) data based upon the research questions and discussed. The study concluded that authentic assessment practices by Social Studies teachers included the occasional guidance they give to their students about how to interpret topics and situations into relevant tasks with a clearly defined goal, and how to relate their knowledge in practical challenges. The study also revealed that refined essays, oral presentations, interviews, case study discussions, and live performances as authentic assessment strategies or tools Social Studies teachers used in assessing their students' learning outcomes in lessons. The study indicated that large class size, traditional assessment (examination) system, insufficient logistics and infrastructure, a paucity of funds to begin various activities and programs, a lack of motivation from school administrators, time constraints and difficulty in developing some authentic assessment tasks coupled with assessing some lessons using authentic assessment method are some of the criteria that influence the effectiveness of authentic assessment execution in teaching Social Studies courses. It is recommended that educational leaders should provide the resources to motivate Social Studies teachers to use authentic assessments for students’ learning in the classroom situation. It is also recommended that, Colleges of Education, Universities and National Teaching Council should organise professional development workshops and seminars to build the capacity of trained Social Studies teachers on the effective uses of authentic assessment practices.
Article
Open Access March 02, 2023

Social Studies Teacher Trainees’ Knowledge and Training on Disaster Risk Reduction in the Selected Colleges of Education in Ghana

Abstract The objective of this study was to assess the knowledge and training on Disaster Risk Reduction among Social Studies teachers’ trainees’ in the Selected Colleges of Education in Ghana. Embedded mixed method and a cross-sectional design was used for the study. The population of the study comprised Social Studies teacher trainees in St. Monicas, Berekum, Tamale, and John Bosco Colleges of Education. [...] Read more.
The objective of this study was to assess the knowledge and training on Disaster Risk Reduction among Social Studies teachers’ trainees’ in the Selected Colleges of Education in Ghana. Embedded mixed method and a cross-sectional design was used for the study. The population of the study comprised Social Studies teacher trainees in St. Monicas, Berekum, Tamale, and John Bosco Colleges of Education. Homogenous purposive sampling technique was used to the four (4) Colleges of Education, convenient sampling technique was used to sample three hundred and nineteen (319) for the quantitative data while homogenous purposive sampling technique ten participants for the qualitative data. The main instrument used for data collection were close-ended questionnaire and interview guide. Legitimation process was adopted to ensure validity and reliability of the data collection instrument. The findings of the study revealed that Social Studies teacher trainees possessed low level of disaster risk reduction kits in their schools. The study also indicated that there was low level of extracurricular activities through which DRR knowledge could be impacted, such logistics should be provided by the various college authorities to help them mitigate disasters.. It is therefore recommended that clubs and Social Studies associations on disasters should be formed in the colleges by the college authorities. Discussions and programmes to be carried out in such associations will enable teacher trainees acquire the necessary knowledge and training needed for disaster risk reduction. It is also recommended that discussions should be tailored to reflect the types of risks and disasters which are not only common to all the colleges of education, but also peculiar to each of them.
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Open Access February 20, 2023

Mainstreaming Disaster Risk Reduction in the Curricular of Colleges of Education in Ghana

Abstract The purpose of this study was to examine Mainstreaming Disaster Risk Reduction in the Curricular of Colleges of Education in Ghana. Mixed method approach and cross-sectional research design were employed in the study. Population of the study comprised all Social Studies teacher trainees, Principals and tutors of the Colleges of Education, officers of the Ghana Education Service and NADMO [...] Read more.
The purpose of this study was to examine Mainstreaming Disaster Risk Reduction in the Curricular of Colleges of Education in Ghana. Mixed method approach and cross-sectional research design were employed in the study. Population of the study comprised all Social Studies teacher trainees, Principals and tutors of the Colleges of Education, officers of the Ghana Education Service and NADMO officials. Purposive sampling technique was used to select 319 Social Studies teacher trainees (99 students from St. Monicas, 67 from Berekum, 73 from Tamale and 80 from John Bosco) Eight (8 Social Studies tutors, four (4) principals, four (4) personnel from the human resource unit of GES of each district, and four (4) NADMO officials. The main instruments used for data collection were questionnaires and interview guide. The study revealed that the extent of the coverage of DRR issues in the curricula of the colleges of education was low. This development leads to a low level of usage of DRR kits and the organization of extracurricular activities on DRR for students. The study also concluded that both teacher trainees and the officials of the Ghana Education Service appreciate the low level of the coverage of DRR in the teaching curricula and the need to take pragmatic measures to address the gaps. It is recommended that, NaCCa, Universities mentoring the colleges of education in Ghana, the Ministry of Education, through the GES, should consider mainstreaming DRR in the curricula of the colleges of education by developing a full subject on DRR for students. This will give teacher trainees and the pupils they teach an in-depth knowledge about disasters and how they could be mitigated. Emphasis should also be placed on how teacher trainees will impact the knowledge to students through the use of logistics and field work.
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Open Access January 01, 2023

Analysis of D- and L- Isomers of (Meth)amphetamine in Human K2EDTA Plasma

Abstract Methamphetamine and its metabolite amphetamine are frequently abused drugs. Whether obtained legally or from clandestine laboratories it is of relevance to determine the chiral makeup of these drugs for investigative purpose. Although urine and oral fluid matrices are commonly offered, less available to independent laboratories are techniques to verify dextro (D-) or levo (L-) (meth)amphetamine [...] Read more.
Methamphetamine and its metabolite amphetamine are frequently abused drugs. Whether obtained legally or from clandestine laboratories it is of relevance to determine the chiral makeup of these drugs for investigative purpose. Although urine and oral fluid matrices are commonly offered, less available to independent laboratories are techniques to verify dextro (D-) or levo (L-) (meth)amphetamine from human K2EDTA plasma. This paper outlines the development and validation of a method that includes the addition of internal standard and a two-step liquid-liquid extraction to remove the analytes from human K2EDTA plasma by triple quadrupole mass spectrometry (LC-MS/MS). The assay was validated according to the United States Food and Drug Administration and College of American Pathologists guidelines, including assessment of the following parameters in plasma validation samples: linear range, limit of detection, lower limit of quantitation, matrix effects, inter- and intra-day assay precision and accuracy, carry over, linearity of dilution, matrix effects and stability. The outcome is a validated and reliable method for the determination of D- and L- isomer concentration of meth(amphetamine) human plasma samples that can be easily adopted by independent clinical laboratories.
Article
Open Access December 25, 2022

Cancer Risk Assessment Tools in Primary Care Settings: An Integrative Review

Abstract Background: There are currently numerous risk instruments available to aid in predicting the present or future chance of getting a cancer diagnosis. It aids in determining a person's likelihood of developing certain cancers by looking at various risk factors, including environmental, behavioral, and genetic. Aim: To analyze the effectiveness of cancer risk assessment techniques [...] Read more.
Background: There are currently numerous risk instruments available to aid in predicting the present or future chance of getting a cancer diagnosis. It aids in determining a person's likelihood of developing certain cancers by looking at various risk factors, including environmental, behavioral, and genetic. Aim: To analyze the effectiveness of cancer risk assessment techniques utilized in primary care settings. Methods: An integrative review of literature Results: Five (5) studies were met the criteria based on the inclusion and exclusion criteria. These tools demonstrated effectiveness in improving patient outcomes and serving as useful therapeutic tools in the primary care setting. Conclusion: Advantages that may aid clinicians in the primary care setting in validating the diagnosis and assisting patients in determining the early signs and symptoms in the diagnosis of cancer. The role of assessment tools can enhance the reliability and caliber of clinical judgment, which can enhance patient outcomes. Implications: The role of healthcare professionals, such as oncologists, nurses, and the healthcare team, on cancer risk assessment in the primary care setting across the lifespan is crucial to ensure a care plan tailored to each patient’s needs.
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Review Article
Open Access November 08, 2022

An evaluation of Eating Pattern and Nutritional Status of Police Personnel in the Tamale Metropolis in Ghana

Abstract Police work is mentally demanding and stressful, which takes a heavy toll on the health of police personnel. This study was conducted to assess the eating pattern, physical activity and nutritional status of police personnel in the Tamale Metropolis. A cross-sectional research design was adopted for the study. The population of this study involved all the 1590 police personnel with two years [...] Read more.
Police work is mentally demanding and stressful, which takes a heavy toll on the health of police personnel. This study was conducted to assess the eating pattern, physical activity and nutritional status of police personnel in the Tamale Metropolis. A cross-sectional research design was adopted for the study. The population of this study involved all the 1590 police personnel with two years working experience within the Tamale Metropolis in the Northern Region of Ghana. Simple random sampling technique was used to select three hundred and eighty-four (384) respondents for the study. The main instrument for data collection was questionnaire. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 21.0. Chi-square and Fisher’s exact tests were used to test associations. Logistic modeling was used to test the strength of the associations. P<0.05 was used to denote significance. The study revealed that the police eat two main meals, skip breakfast or eat in between meals, consume alcohol, ate foods belonging to the meat, soft drinks, fish, grain and eggs groups and their diet were more moderately diverse. The study also concluded the police personnel had normal BMI while was overweight and obese respectively. It is recommended that the police department should institute health education programs on the benefits of good dietary practices to achieve optimal health, to avoid the practice of police eating two main meals, skipping breakfast, consuming more alcohol but rather consumes diet that is moderately diverse to sustain him or her. It is also recommended that police department should institute a health education and screening exercise policy to examine the personals periodically to warrant their good health in the service.
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Open Access August 04, 2022

Effects of Stress on the Job Performance of Psychiatric Nurses

Abstract The purpose of this study was to examine the effects of stress on the job performance of psychiatric nurses in the Ankaful Psychiatric Hospital in Cape Coast. A descriptive survey design was adopted for the study. A sample of 150 psychiatric nurses were selected from a population of 197 psychiatric nurses using a simple random sampling procedure. Data were collected using the Weiman Occupational [...] Read more.
The purpose of this study was to examine the effects of stress on the job performance of psychiatric nurses in the Ankaful Psychiatric Hospital in Cape Coast. A descriptive survey design was adopted for the study. A sample of 150 psychiatric nurses were selected from a population of 197 psychiatric nurses using a simple random sampling procedure. Data were collected using the Weiman Occupational Stress Scale (WOSS) questionnaire. 143 answered questionnaires were retrieved out of the 150 questionnaires offered, giving a 95% return rate. Data were analysed using both descriptive and inferential statistics. The study revealed that the psychiatric nurses' job performance were negatively affected due to the effects of stress, which include mild to severe headache, loss of concentration, exhaustion, anger, overreaction, finding excuses and absence from work, and forgetfulness. The study recommended that the hospital authorities structure the work schedules of psychiatric nurses so that the nurses can get intermittent periods of leave away from work while providing the logistics to make the work of psychiatric nurses easy.
Article
Open Access June 27, 2022

Perceived Interparental Conflicts Irrational Beliefs and Mental Health among Juvenile Offenders

Abstract The present study examines a sample of 140 juveniles. Study aimed to explore the relationship between interparental conflicts, irrational beliefs and mental health. Sample of the study was taken from borstal jail Faisalabad and district jail Lahore. Perceived interparental conflicts scale (CPIC), Irrational beliefs inventory (IBI) and mental health inventory (MHI) was use Results indicated that [...] Read more.
The present study examines a sample of 140 juveniles. Study aimed to explore the relationship between interparental conflicts, irrational beliefs and mental health. Sample of the study was taken from borstal jail Faisalabad and district jail Lahore. Perceived interparental conflicts scale (CPIC), Irrational beliefs inventory (IBI) and mental health inventory (MHI) was use Results indicated that psychological distress has significant positive relationship with interparental conflicts and mental health. Furthermore, it was found that interparental conflicts significantly predict irrational beliefs. The study will give insights into as what type of interparental conflicts predicts irrational beliefs and different mental health problems in juveniles. It may help clinical psychologists/mental health practitioners to develop appropriate ways to manage interparental conflicts, irrational beliefs and mental health problems. Findings of the study may help mental health practitioners to develop appropriate assessment and treatment programs.
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Open Access June 04, 2022

Women’s socio-demographic and cultural factors influencing unmet need for family planning in rural areas of The Gambia: Evidence from a population-based analytical cross-sectional study

Abstract Background: Reproductive health is a critical component of overall health and development. Unmet contraceptive needs are one of the regularly cited measures of the efficacy of family planning (FP) initiatives. This study set out to determine the magnitude and associated factors of unmet need for FP among women of reproductive-aged (15-49 years) in the provincial areas of The Gambia. [...] Read more.
Background: Reproductive health is a critical component of overall health and development. Unmet contraceptive needs are one of the regularly cited measures of the efficacy of family planning (FP) initiatives. This study set out to determine the magnitude and associated factors of unmet need for FP among women of reproductive-aged (15-49 years) in the provincial areas of The Gambia. Methods: The study used a community-based cross-sectional analytical design. A multistage sampling strategy, comprising simple random and cluster sampling, was utilized to obtain a sample of 643 childbearing women (15-49 years) from rural Gambia's sampled clusters. Data collection was conducted using pre-tested structured interview questionnaires. The association was examined using chi-square/fisher's exact test with a significance level of p<0.05. Binary logistic regression analysis was performed to examine the effect of sociodemographic and cultural determinants on unmet FP need, with corresponding computed adjusted odds ratios (aOR). IBM SPSS version 24 was used for data entry and analysis. Results: The unmet need for FP among the study participants was 25.2%; unmet need for spacing and unmet need for limiting was 17.4% and 7.8%, respectively. The total demand for FP was 59.4%, while the satisfaction of demand for FP was 57.6%. The significant predictors of unmet need for FP were woman’s age at first pregnancy (aOR=0.899, p=0.033), LGA of origin (aOR=0.240, p=0.001) and frequency of using contraceptives (aOR=1.587, p=0.032). Conclusion: The present study demonstrated a high unmet need for FP among rural women in The Gambia, with the most often cited reason for non-use being fear of side effects. Hence, it is necessary to concentrate FP services for rural populations, stressing education regarding contraceptive side effects, service quality, and gender equality. Additionally, the study suggests that male participation and religious leaders' involvement in FP programs be strengthened and mainstreamed, as well as the establishment of a communication program that specifically promotes inter-spousal communication.
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Open Access May 22, 2022

Prevalence and predictors of physical activity among female high school students in The Gambia: an institutional-based cross-sectional study

Abstract Background: Everyone, irrespective of age, sex, colour, ethnicity, or present overall fitness level, can benefit from regular exercise. To improve one's health, one must engage in regular physical activity. People with underlying illnesses like long-term impairment can benefit from regular physical activity at the individual level, especially young women. Thus, the current study aimed to [...] Read more.
Background: Everyone, irrespective of age, sex, colour, ethnicity, or present overall fitness level, can benefit from regular exercise. To improve one's health, one must engage in regular physical activity. People with underlying illnesses like long-term impairment can benefit from regular physical activity at the individual level, especially young women. Thus, the current study aimed to assess the prevalence and determinants of physical activity among female school-aged adolescents in the West Coast Region of The Gambia. Methods: The present study used an institutional-based cross-sectional analytical study to collect quantitative data from 384 female high school students in The Gambia. The study used a content-validated, pretested structured questionnaire that consisted of both open and closed-ended questions on physical activity. The data were processed and analyzed using IBM SPSS version 26.0. Descriptive statistics and Chi-square and/or Fisher exact test were used with a p-value <0.15 for inclusion in the logistic regression model. Adjusted odds ratios (aORs) and 95% confidence intervals were calculated, while p-value <0.05 was considered for statistical significance. Results: The proportion of female students involved in physical activity was 37.5%. The mean age of students was 18.8 years with a standard deviation of 1.7 years. Factors such as female students between 17 – 20 years (aOR:3.05, 95% C.I. (1.807 – 5.138)), father never been to school (aOR: 2.82, 95% C.I. (1.495 – 5.334)), primary education (aOR: 2.15, 95% C.I. (1.027 – 4.493)), upper basic school (aOR: 2.31, 95% C.I. (1.055 – 5.074)) and science major students (aOR: 2.21, 95% C.I. (1.203 – 4.047)) had increased odds of involving in PA. Furthermore, students who knew that exercise would strengthen bones (aOR: 2.62, 95% C.I (1.444 – 4.739)), do a planned brisk walking (aOR: 19.16, 95% C.I. (6.698 – 54.811)), basketball/football (aOR: 29.76, 95% C.I. (10.004 – 88.512)) and skipping with rope (aOR: 29.15, 95% C.I. (9.726 – 87.333)) had increased odds to involved in PA after controlling for confounders. Other factors such as students whose mother never been to school (aOR: 0.31, 95% C.I. (0.140 – 0.674)), primary level (aOR: 0.25, 95% C.I. (0.123 – 0.518)), senior secondary level (aOR: 0.42, 95% C.I. (0.189 – 0.935)), nuclear family (aOR: 0.23, 95% C.I. (0.119 – 0.458)) and extended family (aOR: 0.45, 95% C.I. (0.225 – 0.915)) had reduced odds of involving in PA. Conclusion: There is low physical activity among female adolescents in schools. For this, it is imperative that suitable interventions be implemented to raise the level of physical activity among secondary school students. A future intervention for school-aged adolescents could benefit from these findings.
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Open Access May 22, 2022

Pooled prevalence and contextual determinants of contraceptive utilization among reproductive-age women in The Gambia: Evidence from 2013 – 2020 Demographic Health Surveys

Abstract Background: Family planning (FP) methods have been found as an efficient approach of reducing fertility and are therefore widely supported in order to decrease population growth, particularly in poor nations. Promoting contraception availability among women (15 – 49) age has also been shown to be an efficient public health strategy for improving maternal and newborn health outcomes. This [...] Read more.
Background: Family planning (FP) methods have been found as an efficient approach of reducing fertility and are therefore widely supported in order to decrease population growth, particularly in poor nations. Promoting contraception availability among women (15 – 49) age has also been shown to be an efficient public health strategy for improving maternal and newborn health outcomes. This paper aimed at exploring the pooled prevalence of contraceptive uptake and its contextual determinants among women of childbearing age in The Gambia. Methods: The Gambia Demographic and Health Survey (GDHS) in both 2013 and 2019-20 was used for this study. Data were obtained from a pooled 22,098 women aged 15-49 (10,233 for 2013 and 11,865 for 2019-20) through a stratified two-stage cluster sampling approach. Percentages and chi-square tests were used and variables with p-value <0.05 were included into the model. A multivariable logistic regression model was used to assess the predictors of contraceptive usage at 95% confidence interval (CIs) with computed adjusted odds ratios (aORs). All the study data were analyzed using Stata version 15. Results: The weighted pooled prevalence of modern contraceptive utilization in The Gambia was 10.1%. Younger age, compared with women aged 25-29; 30-34; 35-39; 40-44; primary education (aOR=1.25, 95% CI=1.05-1.49); secondary education (aOR=1.57, 95% CI= 1.32-1.85); Higher education (aOR=1.90, 95% CI=1.34-12.69); living in urban areas (aOR=1.49, 95% CI= 1.25-1.79); parity 2-4 (aOR=1.21, 95% CI= 1.01-1.47); told about FP at health facility (aOR=2.97, 95% CI= 2.61-3.38), and no desire for many children (aOR=1.96, 95% CI= 1.62-2.37) were more like to use modern contraceptives among Gambian women. Conclusion: The programme certainly needs to consider improvements in the quality of care being offered to acceptors. Government agencies should target these programs and campaigns on regional FP demands and provide suitable culturally sensitive and regionally adaptive services to the communities' contexts. The programme should intensify its efforts in rural and urban settings to improve accessibility to and availability of FP services.
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Open Access April 23, 2022

Variables Associated with Low Female Participation in College of Education Sports in Central, Western and Western North Regions of Ghana

Abstract The purpose of the study was to examine factors associated with low female participation in colleges of education sports. The population of the study was made up of female colleges of education athletes from Central, Western and Western North Regions of Ghana. Purposive and simple random techniques were used to the colleges of education and the respondents for the study. All the all the six [...] Read more.
The purpose of the study was to examine factors associated with low female participation in colleges of education sports. The population of the study was made up of female colleges of education athletes from Central, Western and Western North Regions of Ghana. Purposive and simple random techniques were used to the colleges of education and the respondents for the study. All the all the six colleges of education were purposively sampled and sampling technique was used to select the one hundred and eighty (180) participants who participate in the College of Education Sports Association (CoESA) games and in the Central, Western and Western North Regions of Ghana were used for the study. The main instrument for the study was a self-structured questionnaire (r= 0.92) containing items based on a five-point Likert scale was used for data collection. The data was analyzed using frequencies, percentages and Chi-square test to determine the relationship among the factors. The study revealed that there is the need for college authorities and female coaches in the colleges of education to take care of female athletes and make adequate provision for more modern sports facilities and equipment to sustain their interest in sports participation. The study recommended that, that the coaches should be mindful of their approach to prospective sportswomen. It is also recommended that, various colleges of education should make a concerted effort to organize programmes and seminars regularly to educate females in the colleges on the career benefits of sports participation and iron out their misconceptions.
Article
Open Access April 17, 2022

Challenges of Instructional Supervision of Social Studies Lessons in the Public Basic Junior High Schools in Ghana

Abstract The purpose of this study was to examine the challenges faced by School Improvement Support Officers, Headmasters and teachers during the instructional supervision of Social Studies lessons in the public basic junior high schools in the Aowin Municipality of the Western North Region of Ghana. The study adopted sequential explanatory research design. The population of the study included School [...] Read more.
The purpose of this study was to examine the challenges faced by School Improvement Support Officers, Headmasters and teachers during the instructional supervision of Social Studies lessons in the public basic junior high schools in the Aowin Municipality of the Western North Region of Ghana. The study adopted sequential explanatory research design. The population of the study included School Improvement Support Officers (SISOs), Headteachers and teachers of selected from Junior High Schools in Aowin Municipality of the Western North Region of Ghana. Purposive sampling technique was used to select ten (10) SISOs and sixty (60) Headteachers in the Aowin Municipality. Stratified, simple random and quota sampling technique was used to select one hundred and twenty (120) teachers for the study. The two main instruments used for data collection were questionnaire and interview guide. The quantitative data entry and analysis was done by using the SPSS version 22 software package. The data was edited, coded and analysed into frequencies, percentages with interpretations. The qualitative data was analysed by the use of the interpretative method. The study revealed that headteachers and School Improvement Support Officers (SISOs) faced challenges such as ; Poor road networks which affected planned supervision; Inability of district directorate to promptly, firmly and fairly acts upon reports from instructional supervision activities from supervisors; Lack of logistics for regular supervision; Insufficient up-to-date knowledge and skills for organizing instructional supervision; and Financial constraints. To overcome the challenges and poor supervisory techniques by headteachers and SISOs, it is recommended that these personnel should be oriented on modern trends in instructional supervision, provided with adequate and sufficient materials for instructional supervision, sufficient funds provided for organizing instructional supervision, the municipal directorate should fairly and firmly implement reports on instructional supervision activities and there should be good motivation package for supervisors to enable them to effectively perform their duties.
Article
Open Access March 21, 2022

Strength Training Guide for Personal Training Practitioners

Abstract Resistance exercise is the performance of physical exercises designed to improve strength, muscular, endurance, hypertrophy, and neuromuscular efficiency with the use of weights (Braith & Stewart, 2006)[1]. Resistance exercise has long been utilized for its beneficial health qualities and propensity to elicit certain desired physiological changes (Fry, 2004)[2]. There has been a recent, and [...] Read more.
Resistance exercise is the performance of physical exercises designed to improve strength, muscular, endurance, hypertrophy, and neuromuscular efficiency with the use of weights (Braith & Stewart, 2006)[1]. Resistance exercise has long been utilized for its beneficial health qualities and propensity to elicit certain desired physiological changes (Fry, 2004)[2]. There has been a recent, and significant, increase in resistance exercise activity in American adults (NCHS, 2018)[3] attributable to factors such as autonomous compulsion and self fulfilment to extrinsic factors like health and physical appearance (Fisher et al., 2017; Heinrich et al., 2014; Ingledew & Markland, 2008)[4,5,6]. As such, there is an ever-increasing need for educational material regarding resistance exercise, its benefits, purpose, and manner in which it should be conducted. Purpose- to (a) provide resistance exercise-based educational material regarding the background and rationale behind resistance training; (b) to provide a specific resistance-based exercise program to elicit strength gain; (c) to provide individuals with the knowledge to safely and effectively engage in said program; and (d) to provide the participant with expected physiological adaptations to completing the program. Methods- Two 6-week, 5-day per week resistance exercise programs – with a brief nutritional guide accompaniment – are outlined for a hypothetical participant, age 25-40, of moderate experience with fitness training, and with the goal of strength gain and moderate fat loss as a secondary goal. Results- Anticipated benefits of the program include: increased maximal strength caused by training above 85% 1RM for 2-6 sets of 1-6 reps; increased synergistic muscle groups strength which will contribute to improved prime mover strength; hypertrophy of skeletal muscles throughout the body, induced by lifts of 67-85% 1 rep max (RM) for 3-6 sets of 6-12 reps and increased resting energy expenditure (basal metabolic rate) accompanied by improved body composition. Conclusion- Continued progression though this protocol with modifications to resistance include potential improved running speed, explosive power potential, and other anaerobic sport performance factors, as well as enhanced neuromuscular efficiency associated with increased prime mover force production capabilities.
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Open Access February 25, 2022

Prevalence and Determinants of Acute Respiratory Infections among Children under Five Years in Rural Settings of The Gambia: Evidence from a National Survey

Abstract Background: Acute respiratory infections (ARIs) generally describe a group of infections caused by a range of organisms whose site of action includes the nostrils, through the pharynx to the alveoli. ARIs are reportedly key contributing factors to childhood morbidities and deaths, with a higher impact on children less than the age of five years. This paper aimed at exploring the prevalence [...] Read more.
Background: Acute respiratory infections (ARIs) generally describe a group of infections caused by a range of organisms whose site of action includes the nostrils, through the pharynx to the alveoli. ARIs are reportedly key contributing factors to childhood morbidities and deaths, with a higher impact on children less than the age of five years. This paper aimed at exploring the prevalence of ARIs and their contextual determinants among children less than 60 months of age in the rural settings of the Gambia. Method: The Gambia Demographic and Health Survey (GDHS) in 2019-20 was used for this study. Data were obtained from 1364 rural women aged 15-49 with children less than 60 months through a stratified two-stage cluster sampling approach. Percentages and chi-square tests were used and variables with p-value <0.15 were included in the model. A multivariable logistic regression model was used to assess the predictors of acute respiratory infection at 95% confidence interval (CIs) with computed adjusted odds ratios (aORs). All the study data were analyzed using Stata version 17. Results: The weighted prevalence of ARIs among children under 60 months of age in the rural Gambia was 37.1% with 95% CI (34.5% - 39.6%). The magnitude of ARI was higher among children 25-60 months age group (38.6%), male children (38.9%) unvaccinated children (42.9%), and those whose fathers and mothers were not working at 60.5% and 38.7%, respectively. In the adjusted model, children whose mother had primary education (aOR=0.65, 95% CI= 0.46-0.91), currently non-breastfed children (aOR=1.40, 95% CI= 1.09-1.79) and those whose father were not working (aOR=2.65, 95% CI= 1.47-4.17) were found to be associated with ARIs among children less than 60 months in The Gambia. Conclusion: The prevalence of ARI was moderately high across children under 5 years of age in rural Gambia, low mother’s educational levels, and unemployed fathers. The program must consider improvements in the quality of care provided to children in both primary, secondary and tertiary healthcare levels in rural settings. Partner support and adapting community-based supporting systems on child health strategies should be strengthened especially in rural settings.
Article
Open Access February 17, 2022

A Geospatial Analysis Approach for Mapping and Ranking of Tourist Corridors in Mashhad Metropolis Iran

Abstract Mashhad is one of the important metropolitans in the northeast of Iran with over 25 million tourists per year. After evaluating the physical space of Mashhad in terms of semantics and identity with the aim of promoting tourism, 127 valuable places with cultural, historical, and religious values were identified, assessed, and analyzed using a Geographic Information Systems (GIS). Therefore, the [...] Read more.
Mashhad is one of the important metropolitans in the northeast of Iran with over 25 million tourists per year. After evaluating the physical space of Mashhad in terms of semantics and identity with the aim of promoting tourism, 127 valuable places with cultural, historical, and religious values were identified, assessed, and analyzed using a Geographic Information Systems (GIS). Therefore, the appropriate distribution of tourist routes for travelers to visit the city of Mashhad was done and 10 corridors and zones were selected. The basis of this choice was the existence of a valuable place at origin and destination of the routes and the existence of appropriate tourism, commercial, welfare and cultural infrastructure and ability to access various uses. Percentage and number of valuable places in each proposed route necessarily meant percentage of the total, excluding repetition in other routes.
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Open Access February 17, 2022

An Investigation into the Factors Contributing to Domestic Violence in Koforidua in the New Juaben Municipality of Ghana

Abstract The purpose of the study was to investigate the factors contributing to domestic violence in Koforidua in the New Juaben Municipality of Ghana. The population of the study consisted of 340 men selected from four communities in Koforidua. Purposive sampling technique 4 communities. Using the Krejcie and Morgan table, a sample size of 340 men were selected which is appropriate for a population of [...] Read more.
The purpose of the study was to investigate the factors contributing to domestic violence in Koforidua in the New Juaben Municipality of Ghana. The population of the study consisted of 340 men selected from four communities in Koforidua. Purposive sampling technique 4 communities. Using the Krejcie and Morgan table, a sample size of 340 men were selected which is appropriate for a population of 3428 with an alpha level of 5 percent in a quantitative study. The selection was based on the fact that these communities registered the highest cases of domestic violence in the Municipality. The main instrument used for the study was structured questionnaire. Data analysed using SPSS (Statistical Product for Service Solution, version 20). Statistical tools such as frequency distribution tables, percentages, charts and cross tabulation was used. The frequency tables were used to give the summary of the data for easy understanding and comparison. The study revealed that men perceive that factors like show of power, exposure to domestic violence, poor communication in marriage, unemployment and poverty, control of women through discipline and women’s low academic achievement are the triggers of domestic violence in a marital relationship. The study recommended that effort ought to be put in place to unravel the mystery surrounding male supremacy over women at both institutional and community levels by DOVVSU, Gender Advocacy Groups and other institutions to benefit humanity and society at large.
Article
Open Access February 10, 2022

A Retrospective, Cross-sectional Hospital-based Study to Determine the Epidemiological, Clinical and Comorbidity Characteristics in Older Adults with Psoriasis

Abstract Background: Psoriasis is extensively studied among middle-aged adults, but not many have studied psoriasis in older adults(geriatrics). OBJECTIVES: To analyze epidemiological, clinical, comorbidities and therapeutic profile of geriatric psoriasis(GP). METHODS: All consenting clinically diagnosed psoriatic patients ≥60 years were divided into two groups: Elderly psoriatic(EP)(60-75 years) [...] Read more.
Background: Psoriasis is extensively studied among middle-aged adults, but not many have studied psoriasis in older adults(geriatrics). OBJECTIVES: To analyze epidemiological, clinical, comorbidities and therapeutic profile of geriatric psoriasis(GP). METHODS: All consenting clinically diagnosed psoriatic patients ≥60 years were divided into two groups: Elderly psoriatic(EP)(60-75 years) and Ultra elderly psoriatic(UP)(>75 years). The dermatologist filled their clinical characteristics’ standardised questionnaire to determine comorbidities, drug interactions profile and compared with age-matched controls using Chi square test. RESULTS: Prevalence of GP is 14.5%(Average age:68 years; Sex ratio=2.5:1)among geriatrics attending dermatology OPD. Most common(49.9%) as well as initial site affected(39.3%) were Palms±Soles. Nummular plaque (90.2%) was most common type. Superficial fungal infection(26.9%) and pruritus(90.8%) were commonly associated cutaneous disease and symptom(p<0.05) respectively. Hypertension(49.7%),Diabetes Mellitus(22.8%), dyslipidemia(25.8%) and Metabolic syndrome(MS)(17.8%) were associated systemic comorbidities. Dyslipidemia and MS(p<0.0001) were more common among GP(163) than controls(963). Drug aggravated psoriasis could not be linked to polypharmacy. Although, topicals were mainstay, oral Methotrexate was most efficacious systemically. CONCLUSION: Our findings suggest a trimodal age of psoriasis onset at 68 years. As age advances, psoriasis severity decreases, unstable guttate lesions decrease; palms±soles commonly involved; infrequent familial occurrence with Polypharmacy not aggravating psoriasis. Active screening for cardiovascular comorbidities in all geriatric psoriasis patients is highly recommended.
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Open Access December 16, 2021

Hallux Valgus Deformity Correction using Proximal Transverse Derotational Metatarsal Osteotomy: A Report of 3 Cases

Abstract To date, numerous operative techniques for hallux valgus correction have been introduced by several authors. The past decades have seen a surge in minimally invasive techniques partly because of the increasing demand for cosmetic surgery. Undoubtedly, the 2nd generation minimally invasive procedure introduced by Bösch et al. largely has an advantage of minimizing scars; but the result [...] Read more.
To date, numerous operative techniques for hallux valgus correction have been introduced by several authors. The past decades have seen a surge in minimally invasive techniques partly because of the increasing demand for cosmetic surgery. Undoubtedly, the 2nd generation minimally invasive procedure introduced by Bösch et al. largely has an advantage of minimizing scars; but the result can vary in the hands of different surgeons. More recently, the 3rd generation Chevron-Akin procedure has demonstrated good results for mild to moderate deformity correction, however, a special equipment such as Shannon burr is required to perform this procedure. In this study, we report the operative outcome of proximal transverse derotational metatarsal osteotomy followed by cannulated screws or Kirschner’s wires fixation across the osteotomy for three patients with moderate hallux valgus. Satisfactory to excellent correction was achieved by lateral translation and supination of the distal fragment for all three cases.
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Case Report
Open Access December 09, 2021

Rural women's socio-demographic and cultural determinants on contraceptive uptake in The Gambia: community-based cross-sectional study

Abstract Background: Family planning is one of the key cornerstones of safe parenthood and a reproductive rights issue. In underdeveloped nations, women experiencing unmet FP needs formed a considerable proportion of all women of reproductive age and are ongoing public health concerns in The Gambia. The study was set out to explore the influence of socio-demographic and cultural factors on [...] Read more.
Background: Family planning is one of the key cornerstones of safe parenthood and a reproductive rights issue. In underdeveloped nations, women experiencing unmet FP needs formed a considerable proportion of all women of reproductive age and are ongoing public health concerns in The Gambia. The study was set out to explore the influence of socio-demographic and cultural factors on contraceptive uptake among rural women in The Gambia. Methods: The study used a community-based cross-sectional analytical design. A multistage sampling strategy, comprising simple random and cluster sampling, was utilized to obtain a sample of 634 childbearing women (15-49 years) from rural Gambia's sampled clusters. Data collection was conducted using pre-tested structured interview questionnaires. The association was examined using chi-square/fisher's exact test with a significance level set at p<0.05. Binary logistic regression analysis was performed to examine the effect of socio-demographic and cultural determinants on uptake of contraceptives, with corresponding computed adjusted odds ratios (aOR). IBM SPSS version 25 was used for data entry and analysis. Results: The uptake of contraceptives among the study participants was 30.4%. The total demand for FP was 59.4% while the satisfaction of demand for FP was 57.6%. The significant predictors of FP uptake were the age of women (aOR=1.097, p=0.014), reason for using FP (aOR=1.139, p=0.011), use of contraceptives before (aOR=24.416, p<0.001) and reason for not discussing FP with a partner (aOR=1.787, p=0.029). Conclusion: The study showed low contraceptive uptake among women in rural communities. Thus, spousal communications on FP concerns are key intermediate steps towards eventual acceptance and sustained usage of FP services. The program should focus on improving access to and availability of FP services in rural areas. The program should prioritize addressing women's needs through consistent community-based interventions including targeted home visits.
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Open Access November 05, 2021

Cerebral Palsy and Heterotaxy Syndrome: A Case Report

Abstract Background: Cerebral palsy is not only a serious neurodevelopmental disease causing significant morbidity in children, but also a traumatic experience leading to psychosocial trauma to the parents/caregivers of the affected children. It is usually caused by prenatal or early post-natal insults to the newborn brain which may be associated with some congenital syndromes like congenital heart [...] Read more.
Background: Cerebral palsy is not only a serious neurodevelopmental disease causing significant morbidity in children, but also a traumatic experience leading to psychosocial trauma to the parents/caregivers of the affected children. It is usually caused by prenatal or early post-natal insults to the newborn brain which may be associated with some congenital syndromes like congenital heart disease with transposition of the viscera but rarely a heterotaxy syndrome, a condition characterized with congenitally abnormal arrangement of the thoracic and abdominal viscera. Method: We present a case report of a 12-month-old boy with neurodevelopmental delay, recurrent episodes of non-mucoid and non-bloody diarhoea, occasional constipation, bilious vomiting, abdominal distension and fever with associated cough and difficulty in breathing. Results: We discuss an unusual presentation of cerebral palsy and heterotaxy syndrome diagnosed clinically with supporting evidence from both laboratory and radiological tests. Cerebral palsy was diagnosed from the history of birth asphyxia, delayed developmental milestone, limb spasticity and low values for all sub-scores of Bayley-III scale. Heterotaxy syndrome was diagnosed from the radiologic evidence of dextrocardia, left-sided stomach, centrally located liver and malrotation of gut with volvulus. We also provide a brief literature review of the incidence and prevalence, causes and risk factors, classification, clinical presentation and associated co-morbidities of heterotaxy syndrome. Conclusion: Diagnosis of heterotaxy syndrome in a child with background cerebral palsy is a great challenge to both physicians and radiologists. This is more so in developing countries due to poor availability of good diagnostic apparatus, therefore, a high index of suspicion is needed. A clear understanding of the clinical features, comprehensive history taking and thorough physical examination are important in making prompt diagnosis. Timely and appropriate imaging is necessary to prevent delays in diagnosis and treatment which lead to poor outcomes.
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Case Report
Open Access September 30, 2021

An Evaluation of the Anti-Fraud Regime in Saudi Arabia from the Islamic Shariah Perspective

Abstract The purpose of this article was to look into Saudi anti-fraud legislation and regulations in order to see how consistent the Kingdom's legal system, which is predominantly found on Islamic principles, is with a wide range of criminal and economic infractions. The main laws relating to fraud were described, and numerous types of fraud were examined, in order to attain this purpose. The discourse [...] Read more.
The purpose of this article was to look into Saudi anti-fraud legislation and regulations in order to see how consistent the Kingdom's legal system, which is predominantly found on Islamic principles, is with a wide range of criminal and economic infractions. The main laws relating to fraud were described, and numerous types of fraud were examined, in order to attain this purpose. The discourse also necessitated an examination of the Islamic perspective on deception and fraud. The analysis revealed that Shariah law, which is concerned with property protection, incriminates and punishes individuals who obtain wealth by illegal methods, the nature of the sanctions, however, is left to the discretion of rulers and judges. Based on this, Saudi legislators have enacted a set of anti-fraud measures. These laws were examined to see how well they addressed economic crimes in the Kingdom. Anti-fraud legislation establishes a legal and regulatory framework compatible with Islamic Shariah for dealing with fraud and economic crimes, with the goal of protecting the public interest, maintaining integrity, and regulating the Kingdom's economy. The primary goal of this study is to explore the challenges and risks associated with enforcing anti-fraud laws in the context of Islamic justice principles. In this study, a descriptive research design was adopted. The key objective of this study is to determine the nature of the problem and analyze the evidence collected. Because of the lack of secondary data and the rigorous restrictions governing the reporting of fraud incidents in Saudi Arabian financial institutions. The study's hypotheses could not be tested substantively because all assumptions concerning the research findings are far-fetched.
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Review Article
Open Access September 23, 2021

Standards for Digitization in Cases of Maps, Documents, and other Relics in the Service of Cultural Heritage

Abstract This paper discusses the analysis of correct digitization practices to follow for maximum performance of the technique. Although it is written for cases that fall within the broader context of culture and cultural heritage, it is ultimately about writing rules that are not limited to the above-mentioned cases, but can be used in more general situations, particularly printed materials. This paper [...] Read more.
This paper discusses the analysis of correct digitization practices to follow for maximum performance of the technique. Although it is written for cases that fall within the broader context of culture and cultural heritage, it is ultimately about writing rules that are not limited to the above-mentioned cases, but can be used in more general situations, particularly printed materials. This paper will therefore discuss the technical characteristics of the choice of digital imaging devices and distinguish the types of quality calculation in the different cases of digitized text, digitized manuscript, digitized maps, and photographs.
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Open Access September 02, 2021

Criminal Legislative Policy in the Protection of Water Resources with Regard to International Treaties: A case for Iranian Legal System

Abstract Human life and survival on Earth depend on the exploitation of diverse resources, including water. Improper use of environmental resources will lead to pollution and destruction. As one of the most sensitive areas of the environment to which human life depends, water is exposed to a variety of environmental pollutants. The protection of the health of water resources has created the need for [...] Read more.
Human life and survival on Earth depend on the exploitation of diverse resources, including water. Improper use of environmental resources will lead to pollution and destruction. As one of the most sensitive areas of the environment to which human life depends, water is exposed to a variety of environmental pollutants. The protection of the health of water resources has created the need for intervention and the use of legal and criminal solutions in organizing their use. Domestic penal policy in the field of legislation, inspired by the provisions of Sharia law, along with local and national considerations for the protection of water resources, has directly and indirectly affected the requirements of accession to international instruments and has enacted regulations on the protection of small water resources.
Article
Open Access September 01, 2021

Decrease of Electrical Systole of Heart: A Review of more than 300 Patients

Abstract Alterations in the cardiac electrical system are the cause of morbidity and a wide variety of symptoms – from mild to those requiring urgent intervention – because of the risk of sudden cardiac death. The most prevalent of these types of electrical disturbances is atrial fibrillation, the incidence of which is growing as the average age of the human being increases. Among many other electrical [...] Read more.
Alterations in the cardiac electrical system are the cause of morbidity and a wide variety of symptoms – from mild to those requiring urgent intervention – because of the risk of sudden cardiac death. The most prevalent of these types of electrical disturbances is atrial fibrillation, the incidence of which is growing as the average age of the human being increases. Among many other electrical heart alterations is one I describe in this document: "The presence of short PR and QTc intervals together in the same ECG tracing”. Methods: A cardiac calibrator was used by four different cardiologists in blinded fashion to document a distinct ECG pattern, that of a short PR and QTc intervals together in the same ECG tracing from more than 2.500 cases assessed for this condition (more than two thousand five hundred cases evaluated since 2.007 to date). Results: Here we describe the clinical features of 330 patients with a documented short PR and QTc intervals together in the same ECG tracing along with descriptions of their symptoms and ancillary investigations. Conclusions: ECG tracing must be studied carefully in patients with suggestive symptoms before declaring normal an ECG tracing with certain defined characteristics.
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Review Article
Open Access August 25, 2021

Green Victimology View in Iranian Criminology System

Abstract Green or environmental victimology is one of the branches of green criminology that emerged in the 1990s with the criminal justice system’s critical origins instead of conventional victimology. In contrast, green victimology believes that human beings can be green victims alongside nature. By following the rules of Iran’s legislative penal policy, green victims can be divided into living and [...] Read more.
Green or environmental victimology is one of the branches of green criminology that emerged in the 1990s with the criminal justice system’s critical origins instead of conventional victimology. In contrast, green victimology believes that human beings can be green victims alongside nature. By following the rules of Iran’s legislative penal policy, green victims can be divided into living and inanimate categories. Living green victims are people, animals, trees, plants, and inanimate green victims divided into air, water, soil, and earth. Although the Iranian legal system considers both groups as green victims and is therefore influenced by a nature-oriented approach, many challenges support them in these regulations, and portraying them can play a valuable role in identifying and protecting them. Green victims play. Therefore, in this study, the first goal is to identify green victims, and the second goal is to express the extent of the legislator’s support for green victims and the challenges it faces.
Article
Open Access July 30, 2021

Air of Uncertainty from Pollution Profiteers: Status of Ambient Air Quality of Sawmill Industry in Ilorin Metropolis, Kwara State, Nigeria

Abstract We can’t stop breathing, but we can do something about the quality of air that we breathe. Clean fresh air is indispensable ingredient for a good life quality. Individuals poses the right towards expecting that the breathed air will not harm people. Thus, fighting air pollution will not only improve health outcomes, productivity, and well-being, it’s also essential toward reducing the emissions of [...] Read more.
We can’t stop breathing, but we can do something about the quality of air that we breathe. Clean fresh air is indispensable ingredient for a good life quality. Individuals poses the right towards expecting that the breathed air will not harm people. Thus, fighting air pollution will not only improve health outcomes, productivity, and well-being, it’s also essential toward reducing the emissions of greenhouse gas as well as fighting climate change. For examples, a third of the global population is at risk from unhealthy of ambient air pollutants concentrations, with the loss of approximately 6.4 million healthy-life-years attributed specifically to chronic exposure to ambient particulate matter. Expert panels have consistently rated air pollution as a greater health hazard than water pollution. Pollution of air is the leading source of unexplained and undiagnosed diseases, besides have remained associated with a variety of serious human health risks, and in fact, a threshold has not been established under which these pollutants exert no adverse effects. This study evaluates ambient air quality at major sawmill sites in Ilorin Metropolis, Kwara State, Nigeria. “Measurements of Air pollution were accurately carried out using direct reading, automatic in situ gas monitors; Hand held mobile multi-gas monitor with model AS8900 [Combustible (LEL), and Oxygen (O2)], BLATN with model BR – Smart Series air quality monitor (PM10, Formaldehyde) and air quality multimeter with model B SIDE EET100 (Dust (PM2.5), VOC, Temperature and Relative Humidity)”. The outcomes disclosed among others, the average concentrations of CO, O2 as well as other measured parameters for instance formaldehyde (HcHo) etc., they are also consistently low as well as within acceptable range in terms of National as well as Global monitoring standards for air quality indices. However, there are few exceptions for instance the average volatile organic compounds (VOCs) concentrations, PM2.5, PM10 as well as Combustible (LEL) respectively, which are higher when compared to National and Global standards. This high figure is due to pollutant amount existing in the sawmills air environment resulting from input of influents from activities of the sawmill. However, as a result, air pollution in the city of Ilorin is found to be increasingly polluted and are of major health concern because of their synergistic action. Due to the high evidences and values, it can lead to a remarkable rise in over-all figure of hospital visits/ patients’ admissions with acute respiratory illnesses as soon as air pollutants level remained high. Hence, there is the need for an aggressive control of ambient air pollution.
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Open Access July 23, 2021

Environmental Protection Regulations in the Light of Public Law and Social Obligations

Abstract Environmental regulation is one of the most important subsets of social regulation. Regulation is a framework for implementing the rules adopted in society, and legal standards guarantee this framework. Thus, if the legislation prohibits the dumping of waste on public waterways and imposes a penalty for its violation, this prohibition can be interpreted as an expression of society's public [...] Read more.
Environmental regulation is one of the most important subsets of social regulation. Regulation is a framework for implementing the rules adopted in society, and legal standards guarantee this framework. Thus, if the legislation prohibits the dumping of waste on public waterways and imposes a penalty for its violation, this prohibition can be interpreted as an expression of society's public commitment to environmental protection and public condemnation of polluting behaviors. On the other hand, it can be said that the destruction of the environment is morally wrong, and therefore the legal prohibition of these behaviors can be interpreted as an expression of this moral claim. This research is based on library studies and descriptive-analytical methods and has an innovative approach. The purpose of this study is to explain the role of law as a facilitator of the executive structure of environmental regulation inappropriate conditions in line with social interaction. It also seeks to explain the importance of regulation and regulation. Regulation is one of the most important social standards and guarantees the strong implementation of legal obligations in society. This fundamental standard has been established in public law and seems to be an important approach to protecting the environment and citizens' adherence to environmental obligations.
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Open Access July 22, 2021

Mapping Shoreline Changes Over the Years: The Case Study of Navarino Bay, Pylos, Messenia, Greece

Abstract This paper deals with the mapping of shorelines through existing maps. Its main purpose is not to give an accurate change of sea level and shoreline in general, but to give guidelines to a more general mapping of shorelines. Geographic Information System (GIS) and paleoenvironmental analysis are powerful tools for archaeology and environmental researches and contributes in such a direction. [...] Read more.
This paper deals with the mapping of shorelines through existing maps. Its main purpose is not to give an accurate change of sea level and shoreline in general, but to give guidelines to a more general mapping of shorelines. Geographic Information System (GIS) and paleoenvironmental analysis are powerful tools for archaeology and environmental researches and contributes in such a direction. Furthermore, this essay will present an analysis of the shoreline changes and the resultant geomorphologies during the prehistoric eras, especially the Mesolithic, Neolithic, and the Helladic eras of the area. The study area which was selected concerns the west part of Messenia Prefecture in Greece. More specifically it concerns the wider area of Pylos and the Navarino bay. The Navarino bay is located near the ancient city of Pylos and the kingdom and palace of Nestor during the Mycenaean period
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Open Access December 27, 2021

Financial Implications of Predictive Analytics in Vehicle Manufacturing: Insights for Budget Optimization and Resource Allocation

Abstract Factory owners and vehicle manufacturers increasingly opt for predictive analytics to inform their decisions. While predictive analytics have been proven to provide insights into the initiation of maintenance measures before a machine actually fails, the right models and features could have a significant impact on the budget spent and resources allocated. This means that financially oriented [...] Read more.
Factory owners and vehicle manufacturers increasingly opt for predictive analytics to inform their decisions. While predictive analytics have been proven to provide insights into the initiation of maintenance measures before a machine actually fails, the right models and features could have a significant impact on the budget spent and resources allocated. This means that financially oriented questions need to at least partially guide the decisions in the planning phase of data science projects. Data-driven approaches will play an increasingly important role, but only a few of the firms that were confident performed logistic regression models for predictive maintenance. Also, from the available knowledge, data-driven classification models connecting vehicle component failures and the occurrence of delays at the assembly line have not been published. This paper utilizes a real-world data-driven approach using classification models in predictive analytics by vehicle manufacturers and thereby links the financial implications of such data science projects to their results. We expand the existing literature on predictive maintenance and possess a unique dataset of newly launched series of vehicles, presented as-is. Our research context is of interest to researchers and practitioners in the automotive industry that manage and plan the final vehicle assembly with just-in-time principles, factoring the consequences of component failures on the assembly process. Key findings of this paper highlight that while minor tweaking of the models is possible, their potential input in decision-making processes for budget optimization is limited.
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Open Access December 27, 2020

Enhancing Pharmaceutical Supply Chain Efficiency with Deep Learning-Driven Insights

Abstract The growing complexity of the operating environment urges pharmaceutical innovation. This essay addresses the need for the integration of advanced technologies in the pharmaceutical supply chain. It justifies the value proposition and presents a concrete use case for the integration of deep learning insights to make data-driven decisions. The supply chain has always been a priority for the [...] Read more.
The growing complexity of the operating environment urges pharmaceutical innovation. This essay addresses the need for the integration of advanced technologies in the pharmaceutical supply chain. It justifies the value proposition and presents a concrete use case for the integration of deep learning insights to make data-driven decisions. The supply chain has always been a priority for the pharmaceutical industry; research and development recognizes companies' increasing investment in big data strategies, with plans for a CAGR in big data tool adoption. The work presented herein has a preliminary explorative character to recuperate and integrate evidence from partly overlooked practical experience and know-how. The practical relevance of the essay is directed toward practitioners in pharmaceutical production, supply chain management, logistics, and regulatory agencies. The literature has shown a long-term concern for enhanced performance in the pharmaceutical supply chain network. This essay demonstrates the application of deep learning-driven insights to reveal non-evident flow dependencies. The main aim is to present a comprehensive insight into deep learning-driven decision support. The supply chain is portrayed in a holistic manner, seeking end-to-end visibility. Implications for public policy are discussed, such as data equity: many countries are protecting their populations and economic growth by building resilience and efficiency to ensure the capacity to move goods across supply chains. The implementation strategy is covered. The combined reduction of variability, efficiency as matured richness, reliability (on stochastic flows and their understanding through deep learning and data), and system noise (increased dampening through the inclusiveness of all stakeholders) results in increased responsiveness of supply chains for pharmaceutical products. Future work involves the integration of external data, closing the loop between planning and its application in reality.
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Open Access December 27, 2021

Predictive Analytics and Deep Learning for Logistics Optimization in Supply Chain Management

Abstract Managing supply chains efficiently has become a major concern for organizations. One of the important factors to optimize in supply chain management is logistics. The advent of technology and the increase in data availability allow for the enhancement of the efficiency of logistics in a supply chain. This discussion focuses on the blending of analytics with innovation in logistics to improve the [...] Read more.
Managing supply chains efficiently has become a major concern for organizations. One of the important factors to optimize in supply chain management is logistics. The advent of technology and the increase in data availability allow for the enhancement of the efficiency of logistics in a supply chain. This discussion focuses on the blending of analytics with innovation in logistics to improve the operations of a supply chain. An approach is presented on how predictive analytics can be used to improve logistics operations. In order to analyze big data in logistics effectively, an artificial intelligence computational technique, specifically deep learning, is employed. Two case studies are illustrated to demonstrate the practical employability of the proposed technique. This reveals the power and potential of using predictive analytics in logistics to project various KPI values ahead in the future based on the contemporary data from the logistics operations; sheds light on the innovative technique of employing deep learning through deep learning-based predictive analytics in logistics; suggests incorporating innovative techniques like deep learning with predictive analytics to develop an accurate forecasting technique in logistics and optimize operations and prevent disruption in the supply chain. The network of supply chains has become more complex, necessitating the need for the latest technological advancements. The sectors that have gained a fair amount of attention for the application of technology to optimize their operations are manufacturing, healthcare, aerospace, and the automotive industry. A little attention has been diverted to the logistics sector; many describe how analytics and artificial intelligence can be used in the logistics sector to achieve higher optimization. Currently, significant research has been done in optimizing logistics operations. Nevertheless, with the explosive volume of historical data being produced by the logistics operations of an organization, there is a great opportunity to learn valuable insights from the data accumulated over time for more long-term strategic planning. To develop the logistics operations in an organization, the use of historical data is essential to understand the trends in the operations. For example, regular maintenance planning and resource allocation based on trends are long-term activities that will not affect logistics operations immediately but can affect the business’s strategic planning in the long run. A predictive analysis technique employed on historical data of logistics can narrow down conclusions based on the future trends of logistics operations. Thus, the technique can be used to prevent the disruption of the supply chain.
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Open Access February 22, 2023

Navigating the Pharmaceutical Supply Chain: Key Strategies for Balancing Demand and Supply

Abstract The pharmaceutical industry is fundamental to global healthcare, providing essential medicines that improve health outcomes and quality of life. However, the demand and supply dynamics within this sector are highly complex, shaped by various factors including demographic changes, evolving disease burdens, technological advancements, regulatory challenges, and economic pressures. This manuscript [...] Read more.
The pharmaceutical industry is fundamental to global healthcare, providing essential medicines that improve health outcomes and quality of life. However, the demand and supply dynamics within this sector are highly complex, shaped by various factors including demographic changes, evolving disease burdens, technological advancements, regulatory challenges, and economic pressures. This manuscript explores the intricate relationship between pharmaceutical medicine demand and supply, focusing on key strategies that can help companies effectively navigate these challenges. The demand for pharmaceutical products is driven by several factors, such as population growth, the aging population, the rise of chronic diseases, and the emergence of new health threats. Additionally, healthcare accessibility, affordability, and policy changes significantly impact the consumption of medicines, while innovations in medical technologies and therapies create new treatment needs. On the supply side, pharmaceutical companies face challenges related to manufacturing capacity, raw material availability, distribution logistics, and compliance with ever-evolving global regulatory frameworks. To address these challenges, the manuscript discusses strategic approaches to managing both demand and supply in the pharmaceutical sector. Key strategies include advanced demand forecasting through data analytics, optimizing supply chains for efficiency and resilience, implementing just-in-time inventory models, and investing in flexible manufacturing systems. Furthermore, global collaboration and partnerships, as well as effective risk management practices, are highlighted as essential to ensuring the availability of medicines, particularly in times of crisis or global health emergencies. This manuscript also delves into the role of policy advocacy and regulatory harmonization in stabilizing the pharmaceutical market, ensuring that medicines are accessible to all populations. In conclusion, the pharmaceutical industry must continually adapt to meet the evolving challenges of demand and supply, embracing innovation and collaboration while maintaining a focus on patient access and global healthcare equity. Through strategic planning and adaptive solutions, the pharmaceutical sector can ensure the continuous availability of critical medicines worldwide, meeting both current and future health needs.
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Open Access December 27, 2021

Innovative Financial Technologies: Strengthening Compliance, Secure Transactions, and Intelligent Advisory Systems Through AI-Driven Automation and Scalable Data Architectures

Abstract Through a digitally connected ecosystem, the innovative realm of fintech significantly enhances human capabilities across various dimensions. AI-based fintech solutions are increasingly proving to be invaluable by providing effective enforcement of regulations that ensure compliance and protect stakeholders involved. Numerous expert investigations conducted in the arena of high-technology [...] Read more.
Through a digitally connected ecosystem, the innovative realm of fintech significantly enhances human capabilities across various dimensions. AI-based fintech solutions are increasingly proving to be invaluable by providing effective enforcement of regulations that ensure compliance and protect stakeholders involved. Numerous expert investigations conducted in the arena of high-technology litigation have reinforced both the pressing need and the immense value of enforced compliance in today's fast-paced digital landscape. Open banking APIs have boldly pioneered this critical regulatory enforcement role, allowing broader access and improved services for consumers. Predictive AI certainty, facilitated through sophisticated validation systems, represented a fundamental evolution in their rule-based legal formulations that govern many aspects of financial transactions. These advanced products were deployed within global legislative codes, allowing for standardized practices, and consequently, all market sectors quickly adopted them to ensure they remain competitive and compliant. During the latest of these professionals' encouraging comments, it became clear that awareness of the inception of these groundbreaking innovations must be convened into a steadfast commitment to continue launching natural language processing products that can refine consumer interaction. Since this pivotal point, the increasing dependency of the financial expert community on these incisive factors underscores the paramount importance they now hold for their clients and end users alike, shaping the future of finance in profound ways [1].
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Open Access December 27, 2019

Transforming the Retail Landscape: Srinivas’s Vision for Integrating Advanced Technologies in Supply Chain Efficiency and Customer Experience

Abstract Technological advances have had a transformative impact on the retail landscape. Challenges arise with guaranteeing technological changes lead to, rather than detract from, increased efficiency and positive experiences. First, integrating technology into the supply chain in an aggressive way is costly. It requires vast changes to existing systems and developments of cross-industry communication [...] Read more.
Technological advances have had a transformative impact on the retail landscape. Challenges arise with guaranteeing technological changes lead to, rather than detract from, increased efficiency and positive experiences. First, integrating technology into the supply chain in an aggressive way is costly. It requires vast changes to existing systems and developments of cross-industry communication protocols. Secondly, the public is often quick to reject technological changes or slow to become users. Finally, ensuring that technological advancements do not only benefit the top few retailers and are accessible to those of any size poses a challenge, as has been seen in the fate of only a handful of radical changes in retail technology. On the other hand, an integral aspect of technology, particularly that used for big data collection and processing, is that it can account for these and other variables. It can predict the success of ventures into modernizing or developing new systems and can identify more effective and efficient ways to do so. Of course, the concerns of job loss or technological monopoly still loom. But, it would seem, the continued advancement of technology in the retail landscape is inevitable.
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Open Access December 27, 2020

Designing Self-Learning Agentic Systems for Dynamic Retail Supply Networks

Abstract The evolution of supply chains (SC) from a linear to a network structure created an opportunity for new processes, product/service offerings, and provider-business. Rising customer service expectations have led to the need for innovative SC designs to develop and sustain competitive performance globally. Firms are forced to respond and adapt accordingly, thereby leading to design, network, [...] Read more.
The evolution of supply chains (SC) from a linear to a network structure created an opportunity for new processes, product/service offerings, and provider-business. Rising customer service expectations have led to the need for innovative SC designs to develop and sustain competitive performance globally. Firms are forced to respond and adapt accordingly, thereby leading to design, network, operational, and performance dynamics. Traditionally, SCs are treated as static structures, focusing solely on design and/or operational optimization. Such perspectives are not viable options for SC domains, as they address only a portion of the dynamic problem space, use a deterministic assumption of dominant design variables, capitalize on past data to predict future decisions, and offer pre-classified forecasting options complemented with a limited comprehension of systemic SC elasticity. Novel self-learning agentic systems are proposed that blend the sciencematics of SC decisions and dynamics. The designs guide firms seeking to build adaptive SCs using operational decision processes. The designs address the agentic nature of SC, embedding computational interaction models of firm SC networks. The designs contrast the stochastic action-taking and thereby the performance outcomes, discovering opportunities for adaptive operational designs of SC tasks. Fine-tuning and meta-learning are new design capabilities that adapt to evolving dynamic environments. Frameworks for behavioral customization and systematic exploration of the design space are provided as user guides. Exemplar designs are also provided to serve as a translation template for users to express operational models of their own contexts. To account for the dynamics of supply chains (SC), agent-based models are increasingly adopted. Such models exhibit SC structure and/or formulation dynamics. Though existing efforts commence adjacent-only structural changes, dynamism with respect to tasks is crucial for SC design and operational strategy development. Proposed is a process modeling library and workflow for discovering intricate designs of adaptive agentic systems. The library revises Dataflow and Structure, concealing sequencing and context designs of processes. Prompted specifications describe and enact designs. Applications in SC formulation discovery are provided.
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Open Access December 27, 2022

Towards the Efficient Management of Cloud Resource Allocation: A Framework Based on Machine Learning

Abstract In the constantly evolving world of cloud computing, appropriate resource allocation is essential for both keeping costs down and ensuring an ongoing flow of apps and services. Because of its adaptability to specific tasks and human behavior, machine learning (ML) is a desirable choice for fulfilling those needs. This study Efficient cloud resource allocation is critical for optimizing performance [...] Read more.
In the constantly evolving world of cloud computing, appropriate resource allocation is essential for both keeping costs down and ensuring an ongoing flow of apps and services. Because of its adaptability to specific tasks and human behavior, machine learning (ML) is a desirable choice for fulfilling those needs. This study Efficient cloud resource allocation is critical for optimizing performance and cost in cloud computing environments. In order to improve the precision of resource allocation, this study investigates the use of Long Short-Term Memory (LSTM). The LSTM model achieved 97% accuracy, 97.5% precision, 98% recall, and a 97.8% F1-score (F1-score: harmonic mean of precision and recall), according to experimental data. The confusion matrix demonstrates strong classification performance across several resource classes, while the accuracy and loss curves verify steady learning with minimal overfitting. The suggested LSTM model performs better than more conventional ML (machine learning) models like Gradient Boosting (GB) and Logistic Regression (LR), according to a comparative study. These findings underscore the LSTM (Long Short-Term Memory) model’s robustness and suitability for dynamic cloud environments, enabling more accurate forecasting and efficient resource management.
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Open Access December 27, 2021

Digital Transformation in Insurance: Migrating Enterprise Policy Systems to .NET Core

Abstract Migrating enterprise policy systems to .NET Core is a key objective of digital transformation in the Insurance IT ecosystem. This change directly addresses strategic drivers: enabling adoption of cloud-first development, resisting market pressure for more flexible and usable enterprise solutions, and preparing for changing demands from regulation and compliance. Phases of operational benefit [...] Read more.
Migrating enterprise policy systems to .NET Core is a key objective of digital transformation in the Insurance IT ecosystem. This change directly addresses strategic drivers: enabling adoption of cloud-first development, resisting market pressure for more flexible and usable enterprise solutions, and preparing for changing demands from regulation and compliance. Phases of operational benefit aligned with risk mitigation form the basis of the migration roadmap, with a strong focus on engaging all relevant stakeholders. Market pressure for a SEAMLESS user experience across ALL applications is a fundamental driver for Investment in digital transformation. Gaps remain in enterprise Operations, where Legislative and regulatory accountability Demand rigid and complex solutions that Liberty has not yet been able to provide. New risk-based capital requirements, Data-Sovereignty controls, Controls for sensitive Data in the Cloud, and new Audit requirements create a long list of challenges for the ecosystem that can no longer be Deferred. At the same time, Cross-organisational integration is becoming more important and integrating partners from the insurance supply-chain requires a much more flexible approach to development and Deployment. These factors combine to generate a credible case for accelerated digital investment with a focus on Migration to Cloud Platforms, with related Risk mitigation, Quality Improvements, and flexibility benefits that close Industry gaps.
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